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Journal : CERATA

Penetapan Kadar Asam Lemak Bebas (Alb) Pada Minyak Goreng Kemasan Dan Minyak Goreng Curah Dengan Perlakuan Berdasarkan Lama Waktu Pemanasan Khoirul Mahmudah; Vivin Nopiyanti
CERATA Jurnal Ilmu Farmasi Vol 10 No 1 (2019): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v10i1.67

Abstract

Cooking oil is one of the ingredients needed by the community, especially house wives and made from oi lpalm. Free fatty acids are not separated from cooking oil which causes bad effects on humans. This study aims to determine the levels of free fatty acids (FFA) in packagedcookingoilandbulkcookingoilbytreatmentbasedonheatingtime .This study uses the sample used in this study, bulk cooking oil taken from the markets of Mojosongo, Surakarta and 3 samples of packaged cooking oil which are sold in Surakarta Supermarket in January 2019. This research method uses acid base titration. The time used for analysisis 0 ', 15', 30 ', 45', 60 ', 75'at 160 and compares the levels with the Cooking Oil Quality Standards .The results of this study indicate the levels of free fatty acids in cooking oil, sample A heating to 0,1,2,3 was 0,16%; 0,20%; 0,22%; 0,25% according to SNI while heating to 4, 5 was 0,33%; 0,40% did not meet SNI standards. Sample B warmed up to 0,1,2,3,4,5 which were 0,12%; 0,14%; 0,15%; 0,17%; 0,21%; 0,24%, Sample C warmed up to 0,1,2,3,4,5 which were 0,12%; 0,16%; 0,19%; 0,21%; 0,22%; 0,24%; Sample D warms up to 0,1,2, 3,4,5 whichwere 0,12%; 0,14%; 0,16%; 0,18%; 0,21%; 0,24% according to the Cooking Oil Quality Standards.
Formulasi dan Uji Aktivitas Perlindungan Tabir Surya Emulgel Ekstrak Etanol Kulit Bawang Merah (Allium cepa L.) secara In Vitro dan In Vivo Vivin Nopiyanti; Lisa Wulandari; Suhartinah
CERATA Jurnal Ilmu Farmasi Vol 12 No 1 (2021): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v12i1.150

Abstract

Sunscreen is a preparation used on the surface of the skin that works to absorb, scatter, or reflect ultraviolet light. Skin of red onion (Allium cepa L.) is one of the natural ingredients that can be used as sunscreen, especially the. Skin of red onion contains flavonoid and tannin compounds that have the potential as sunscreen. This study aims to find out the ethanol extract skin of red onion in the form of emulgel preparations that have good physical quality and stability, SPF value and sunscreen protection activities. Ethanol extract skin of red onion is obtained by maceration using 50% ethanol solvents. Emulgel ethanol extract skin of red onion is made in 4 formulas with variations in extract concentrations of 0,05% ; 0,1% and 0,2%. Emulgel preparations are carried out physical quality test, stability, determination of SPF value (Sun Protection Factor) in vitro using UV-Vis spectrophotometry. The SPF value is calculated by the Mansyur equation. The in vivo test used a male rabbit (New Zealand) were irradiated with a UV B exoterra lamp for 24 hours to see the resulting effects of erythema. The results showed that the onion peel ethanol extract emulgel had good quality and stability. Sunscreen protection tests in vitro and in vivo showed that the sunscreen protection activity met the requirements for the effectiveness of sunscreen with an SPF value of emulgel with a concentration of 0,05% ; 0,1% and 0,2% of 9,59 classified as protection extra, 21,14 and 35,85 were classified as ultra protected and the erythema score after 24 hours of UV exposure was 0.
PENGARUH METODE PENGGERUSAN TABLET VITAMIN C TERHADAP KADAR AKTIF DENGAN MENGGUNAKAN METODE SPEKTROFOTOMETRI UV-VIS Dyah Putri Santoso, Marryna; Nopiyanti, Vivin
CERATA Jurnal Ilmu Farmasi Vol 13 No 1 (2022): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v13i1.457

Abstract

Meracik sediaan serbuk merupakan salah satu bentuk pelayanan resep. Sediaan pulveres yang biasa disebut puyer biasanya berasal dari sediaan tablet. Teknik penggerusan sediaan pulveres umumnya menggunakan mortir-stamper dan alat blender (pulverization). Penggerusan dengan menggunakan alat blender dapat mempercepat proses penggerusan dan lebih praktis, tetapi panas yang ditimbulkan pada alat blender dikhawatirkan mampu menurunkan kadar aktif pada suatu sediaan yang memiliki bahan aktif tidak stabil terhadap adanya panas. Penelitian ini bertujuan untuk mengetahui kadar aktif pada tablet vitamin C yang telah dilakukan penggerusan dengan metode blender dan mengetahui apakah penggerusan dengan metode blender dapat mempengaruhi kadar aktif terhadap tablet vitamin C. Sampel pada penelitian ini ada 3 macam merek tablet vitamin C yang dijual di salah satu apotek di Surakarta. Ada 2 macam perlakuan yaitu tablet vitamin C yang digerus dengan metode blender dan tablet vitamin C yang tanpa perlakuan. Uji kualitatif dilakukan dengan menggunakan pereaksi KMnO4, Iodium, Fehling A dan Fehling B yang menunjukkan hasil positif. Uji kuantitatif menggunakan metode Spektrofotometri UV-Vis dengan panjang gelombang 266nm. Hasil penelitian ini pada tablet vitamin C dengan metode Spektrofotometri UV-Vis terdapat kadar asam askorbat pada sediaan tablet vitamin C blender (1) 45,11±0,494mg/tablet, tablet vitamin C blender (2) 45,93±0,275, tablet vitamin C blender (3) 44,12±0,684mg/tablet. Berdasarkan penelitian ini penggerusan dengan metode blender dapat menyebabkan penurunan kadar vitamin C dibandingkan dengan hasil tablet vitamin C yang tanpa perlakuan.