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All Journal Prosiding Seminar Biologi Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) AGRIVITA, Journal of Agricultural Science Indonesian Journal of Pharmaceutical Science and Technology Indonesian Journal of Biotechnology Majalah Obat Tradisional INDONESIAN JOURNAL OF PHARMACY Universa Medicina Jurnal Biodjati Majalah Farmaseutik OLDI (Oseanologi dan Limnologi di Indonesia) JSFK (Jurnal Sains Farmasi & Klinis) JFIOnline Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Kefarmasian Indonesia
Subagus Wahyuono
Faculty of Pharmacy, Universitas Gadjah Mada Yogyakarta
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Earth & Planetary Sciences Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Physics Public Health

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KARAKTERISTIK PARAMETER SPESIFIK DAN NON SPESIFIK DAUN KRATOM (Mitragyna speciosa Korh.) ASAL KALIMANTAN SELATAN Febrianti, Dwi Rizki; Wahyuono, Subagus; Fakhrudin, Nanang; Riski, Akhmad; Kumalasari, Eka; Normilawati; Niah, Rakhmadhan; Mar'uf, Muhammad
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 10 No 2 (2025): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v10i2.2786

Abstract

Standardization is a process of fulfilling the requirements for raw materials of traditional medicine, aimed at ensuring and maintaining safety, consistent quality, and efficacy. Kratom leaves (Mitragyna speciosa) are a traditional medicinal plant found in the interior regions of Kalimantan. This plant functions as a source of energy due to its stimulant properties. This study aims to determine the standardization of kratom leaf extract simplicia, including both specific and non-specific parameters. The extraction method used in this study was maceration with ethanol. The results showed that the scientific name of kratom leaves is Mitragyna speciosa. The standardization of kratom leaf simplicia powder includes parameters such as loss on drying, total ash, water-insoluble ash, acid-insoluble ash, total microbial count (ALT), total yeast and mold count (AKK), and heavy metal contamination, with the following results: 9.5%; 5.51%; 3.58%; 0.39%; 6.9 × 10² cfu/g; >3.0 × 10³ cfu/g; <0.001 mg/kg. Meanwhile, the standardization of kratom leaf extract includes ash content and heavy metal contamination, with results of 6.06% and <0.001 mg/kg, respectively. The active compounds contained in the kratom leaf simplicia and extract are alkaloids, flavonoids, and tannins.
Co-Authors . HERNAYANTI Abdul Rohman Aditya Krishar Karim Ag. Yuswanto Ahmad Hamim Sadewa Ali Djamhuri Ambarwati Ari Sartinah, Ari Ariani Hatmanti Arief Nurrochmad Baiq Maylinda Gemantari Bambang Hariono Djoko Santoso Eka Kumalasari Eltivitasari, Andita Endang Lukitaningsih Erna Prawita Setyowati Farisya Nurhaeni Febrianti, Dwi Rizki Galih G, Galih Gani, Andayana Puspitasari Gemini Alam Hadi, Etik Erna Wati Ibnu G Gandjar, Ibnu G Ibnu G. Ganjar, Ibnu G. Ida Ayu Putu Sri Widnyani Imono Argo Donatus, Imono Argo Isnindar Isnindar JAKA WIDADA Kumiko Terada Kusnanto, Chelvin Ari KV Rao, KV L. Hartanto Nugroho LANGKAH SEMBIRING Linus Yhani Chrystomo Mae Sri Hartati Wahyuningsih Mar'uf, Muhammad Marchaban Marchaban, Marchaban Marchaban, . Marchaban, . Mark T Hamann, Mark T Mimiek Murrukmihadi Moch. Saiful Bachri Nanang Fakhrudin, Nanang Niah, Rakhmadhan Normilawati Nunung Yuniarti Peni Susilowati Putri, Peni Susilowati Pratiwi, Sylvia Prihandiwati, Erna Puji Astuti PUSPITA LISDIYANTI Ririn Suharsanti, Ririn Riski, Akhmad Romadhonsyah, Fitra S.M. Widyastuti Samsul Hadi Sofia Mubarika Haryana Sri Sudewi, Sri Sri Wahdaningsih Sudibyo Martono Sugeng Riyanto Sukarti Moeljopawiro Sutomo Sutomo Tanti Azizah S Tatsuo Takeya, Tatsuo Tri Lestari Tri R Nuringtyas, Tri R Triana Hertiani Tsutomu Nohno Widyastuti, SM