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All Journal Jurnal Pendidikan Vokasi Medicina E-Jurnal Medika Udayana Jurnal Kesehatan Andalas MNJ (Malang Neurology Journal) Bali Journal of Anesthesiology Indonesian Journal of Medicine Adimas : Jurnal Pengabdian Kepada Masyarakat Callosum Neurology Journal : Jurnal Berkala Neurologi Bali ISM (Intisari Sains Medis) : Jurnal Kedokteran DIKEMAS (Jurnal Pengabdian Kepada Masyarakat) Majalah Kedokteran Neurosains Kumawula: Jurnal Pengabdian Kepada Masyarakat Bali Anatomy Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Cermin Dunia Kedokteran Jurnal Locus Penelitian dan Pengabdian Hang Tuah Medical Journal Neurona Cermin Dunia Kedokteran Jurnal Teknik Elektro dan Komputasi (ELKOM)
I Putu Eka Widyadharma
Departemen Neurologi, Fakultas Kedokteran Universitas Udayana, Denpasar, Bali
Aerospace Engineering Automotive Engineering Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Pelatihan penggunaan Mesin Automatic Chopper and Dryer for Brown Sugar Untuk Meningkatkan Mutu dan Produktivitas Pada UMKM Kuliner Sate Ayam di Kabupaten Ponorogo Hakim, Aulia El; Sudirman, Dirvi Juliando; Setyawan, Sulfan Bagus; Widyadharma, Andhika Putra; Yudha, R. Gaguk Pratama; Junaedi, Imam; P, Rakhmad Gusta; Saputra, Angga Dwi; Mahmud, Ahmad Ulil Albab
DIKEMAS (Jurnal Pengabdian Kepada Masyarakat) Vol 8 No 1 (2024)
Publisher : Politeknik Negeri Madiun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32486/dikemas.v8i1.718

Abstract

Gula merah dijadikan bahan baku berbagai industri pangan seperti industri kecap, tauco, dan berbagai produk untuk makanan tradisional. Dalam proses pengolahan gula merah menjadi bahan baku industri kuliner, Gula merah harus dirajang (dicacah) dan dikeringkan terlebih dahulu untuk mendapatkan bahan baku yang berkualitas. Proses pencacahan gula merah sebagai bahan baku industri kuliner masih menggunakan peralatan sederhana seperti, pisau yang digerakkan dengan tangan (konvensional) dan proses pengeringan yang masih memanfaatkan sinar matahari. Dari hasil pengamatan secara langsung Pada UMKM kuliner sate ayam Ponorogo Pak Slamet Jl. Raya Ngumpul, Ngumpul, Balong, Ponorogo, belum terdapat alat atau sebuah terobosan untuk mengatasi permasalahan tersebut. terdapat dua permasalahan yang dihadapi, yang pertama adalah saat proses pencacahan gula merah masih menggunakan metode konvensional, dilakukan dengan cara manual dan kurang steril karena dilakukan dengan menggunakan peralatan sederhana seperti pisau dan kayu. Permasalahan yang timbul tersebut tentu sangat tidak efisien dan tidak steril dan menyebabkan kualitas gula merah menurun untuk dijadikan bahan baku kuliner sehingga menyebabkan kerugian dan menghambat aktifitas yang dijalankan. Kegiatan Pengabdian Kepada Masyarakat yang akan dilakukan bertujuan untuk mengatasi permasalahan tersebut. Kegiatan yang dilakukan dimulai dari Proses Validasi Alat pencacah dan pengering gula merah " Automatic Chopper and Dryer Machine " yang sudah dibuat, kemudian Proses Pelatihan penggunaan Alat pencacah dan pengering gula merah " Automatic Chopper and Dryer Machine " sampai proses Hibah alat pencacah dan pengering gula merah yang diberikan UMKM kuliner sate ayam Ponorogo Pak Slamet.
Weaving Activity and High Plasma Levels of Brain-Derived Neurothrophic Factor (BDNF) As A Protective Factors Against Cognitive Dysfunction in Middle-Aged Women Yuniarni, Ruth Sharon; Widyadharma, I Putu Eka; Juhanna, Indira Vidiari; Rumai, I Made Winarsa; Dewi, Ni Nyoman Ayu; Komalasari, Ni Luh Gede Yoni
Jurnal Locus Penelitian dan Pengabdian Vol. 4 No. 8 (2025): JURNAL LOCUS: Penelitian dan Pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v4i8.4671

Abstract

Cognitive dysfunction is a common problem associated with ageing and affects quality of life. As a repetitive activity, weaving and brain-derived neurotrophic factor (BDNF) levels are believed to be essential in maintaining cognitive function. This study aims to prove the relationship between weaving activity, BDNF levels, and cognitive dysfunction. This study is an observational study with a case-control design. The study subjects were middle-aged women (45–59 years) divided into two groups: CD (cases) and non-CD (controls). CD status was determined using the Mini-Mental State Examination (MMSE) score. Weaving activity was assessed through a questionnaire, with the criterion for active weaving being at least 3–5 times per week (minimum 60 minutes per session), categorised as weaving (+) and non-weaving (–). Plasma BDNF levels were measured using an ELISA kit and categorised as high BDNF (+) and low BDNF (–) based on the mean value. The researchers performed statistical analysis using the Chi-Square test and logistic regression. The Chi-Square test showed a significant association between weaving activity as a protective factor against CD occurrence (p < 0.001; OR: 0.038) and high BDNF levels as a protective factor against CD occurrence (p < 0.001; OR: 0.013). Multivariate analysis using logistic regression indicated that weaving activity (p = 0.001; AOR: 0.028; CI: 0.003–0.247) and high BDNF levels (p < 0.001; AOR: 0.011; CI: 0.001–0.100) were independent protective factors against CD occurrence. This study indicates that weaving activity and high plasma BDNF levels are independent protective factors against CD.
PELATIHAN PERAKITAN DAN PEMROGRAMAN JAM SHOLAT DIGITAL OTOMATIS DI PONDOK PESANTREN AL IHSAN KABUPATEN MADIUN Pribadi, Wahyu; Widyadharma, Andhika Putra; Sutantohadi, Alief; Putra, Rakhmad Gusta; Kusuma, Yohan Intan; Syah Putra, Muhammad Dio; Priandwika, Muhammad Rifki Agung; Yudhiatama, Galang Dafa; Abdullah, Fachrul Rizky; Nadia, Hana Jasmine
ADIMAS Jurnal Pengabdian Kepada Masyarakat Vol 7 No 2 (2023): September
Publisher : Universitas Muhammadiyah Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24269/adi.v7i2.6069

Abstract

Pondok pesantren adalah lembaga pendidikan islam dengan sistem asrama. Pondok Pesantren Al Ihsan merupakan salah satu Lembaga pendidikan islam di Kabupaten Madiun yang mempunyai misi dalam pengembangan keilmuan terutama di bidang teknologi kepada para santri. Kegiatan pengabdian ini mengangkat tema peningkatan keterampilan santri dalam penguasaan teknologi di bidang elektronik dan sistem digital melalui pelatihan perakitan dan pemrograman jam sholat digital otomatis yang dilaksanakan terdiri atas empat tahapan. Tahapan pertama adalah persiapan berupa identifikasi permasalahan dari Pondok Pesantren Al Ihsan sebagai mitra. Tahapan kedua yaitu pelaksanaan sosialisasi dan pemberian materi mengenai program pengabdian masyarakat dan pengetahuan dasar terkait jam sholat digital otomatis kepada para santri Pondok Pesantren Al Ihsan. Tahapan ketiga yaitu pembuatan jam sholat digital otomatis oleh tim pengabdi masyarakat dari Politeknik Negeri Madiun bersama para santri Pondok Pesantren Al Ihsan. Tahapan terakhir yaitu monitoring program untuk mengetahui perkembangan termasuk kendala program dan mencari solusi permasalahan. Target yang diharapkan adalah peningkatan keterampilan dan pemahaman santri terhadap perkembangan teknologi melalui sinergi antara perguruan tinggi dan mitra. Berdasarkan data survei pemahaman santri terhadap program pengabdian menunjukkan bahwa 58% sangat paham, 42% paham, dan 0% tidak paham. Kesimpulan, santri dapat memahami materi pelatihan perakitan dan pemrograman jam sholat digital otomatis.
A Neuroinflammatory Biomarker Profile Associated with Neuropathic Pain in Hansen's Disease: A Systematic Review and Meta-Analysis of S100B, TNF-α, and IL-6 Dian Rizki Fitria; I Putu Eka Widyadharma; Ni Made Susilawathi
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 10 No. 1 (2026): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v10i1.1475

Abstract

Background: Neuropathic pain (NP) is a severe, chronic complication of Hansen's disease (HD), persisting after antimicrobial therapy and profoundly diminishing quality of life. Its pathophysiology is driven by persistent, complex neuroinflammatory processes within the peripheral nervous system. Circulating biomarkers, especially the glial-derived protein S100B, offer a potential objective window into this underlying pathology. This study aimed to meta-analyze the association between circulating S100B, TNF-α, and IL-6 and the presence of NP in patients with HD. Methods: A systematic search of PubMed, Scopus, and Web of Science databases was conducted for observational studies published between January 2015 and December 2025 that compared biomarker levels in HD patients with and without NP, diagnosed using validated screening instruments. Data from eligible studies were extracted independently, and methodological quality was assessed using the Newcastle-Ottawa Scale. A random-effects meta-analysis was performed to compute the pooled standardized mean difference (SMD) with 95% confidence intervals (CIs) for each biomarker. Results: Seven studies, comprising 812 patients (405 with NP, 407 without NP), met the inclusion criteria. The meta-analysis revealed that serum S100B levels were significantly elevated in HD patients with NP compared to those without (SMD = 1.28, 95% CI [0.95, 1.61], p < 0.001). This finding was accompanied by very high statistical heterogeneity (I² = 78%). Concurrently, the analysis demonstrated significantly higher circulating levels of TNF-α (SMD = 0.89, 95% CI [0.62, 1.16]) and IL-6 (SMD = 0.75, 95% CI [0.48, 1.02]) in the NP group. Conclusion: This meta-analysis establishes a strong statistical association between a distinct neuroinflammatory biomarker profile—characterized by elevated circulating S100B, TNF-α, and IL-6—and the presence of neuropathic pain in Hansen's disease. S100B, as a marker of Schwann cell distress, is a particularly relevant component of this profile. These findings underscore the pivotal role of neuroinflammation in HD-related NP, although the high heterogeneity and non-specific nature of these systemic markers necessitate a cautious interpretation regarding their immediate clinical applicability.
KONSEP BARU DALAM BIOLOGI MOLEKULER PADA NEUROPATI DIABETIK PERIFER Widyadharma, I Putu Eka; de Liyis, Bryan Gervais
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 41 No 5: Edisi Suplemen Neurona Bekerjasama dengan JogjaCLAN 2025
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v41i5.859

Abstract

Plasma Serotonin Levels and Depression Scores in Informal Caregivers of Patients with Dementia and without Dementia: A Systematic Review Widyadharma, I Putu Eka; Budaya, I Made Maha Candra; Widyastuti, Ketut
Indonesian Journal of Medicine Vol.11 No.1 (2026)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2026.11.1.913

Abstract

Background: Depression frequently affects informal caregivers, particularly those caring for dementia patients due to greater emotional and caregiving burdens. This study aims to compare depression levels and plasma serotonin concentrations between dementia and non-dementia caregivers. Subjects and Method: A systematic review was conducted using PRISMA guidelines. Articles were searched from PubMed, ScienceDirect, and Google Scholar between 2015–2024 using the keywords: dementia caregiver, non-dementia caregiver, depression, and serotonin. Nine primary observational studies met the inclusion criteria: full-text availability, adult informal caregivers, and quantitative measurement of depression and/or serotonin. Data were synthesized narratively. Results: Most studies demonstrated higher depression levels among dementia caregivers compared to non-dementia caregivers. Emotional distress, patient behavioral symptoms, and caregiving duration were identified as major contributing factors. One study showed lower plasma serotonin associated with higher depressive scores, supporting possible biological involvement. Conclusion: Dementia caregivers exhibit greater depressive symptoms than non-dementia caregivers, potentially linked to caregiving burden and serotonin imbalance. Early psychological screening and targeted support interventions are recommended.
Curriculum and learning management: Integration of creative economy value to improve students' life skill Yes Matheos Lasarus Malaikosa; Andhika Putra Widyadharma; Widya Trio Pangestu
Jurnal Pendidikan Vokasi Vol. 12 No. 1 (2022)
Publisher : ADGVI & Graduate School of Universitas Negeri Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21831/jpv.v12i1.44253

Abstract

The impact of the ASEAN economic community on the development of industry 4.0 is increasingly massive. The education system needs a new buzz to respond to the development of industry 4.0. The Indonesian government continues to make changes and developments in the field of education to prepare learners to become knowledgeable, capable, creative, independent, and responsible human beings. The research uses a qualitative approach, with data collection techniques through observation, interview, and one in the documentation of strengthening life skills with integrase creative economic value. In this study, researchers successfully interviewed the principal, teacher, student, and creative ruler of the alumni element of Grafika Desa Putera Vocational High School (SMK Grafika Desa Putera). The results showed that  SMK Grafika Desa Putera integrates the important value of the creative economy for students in adaptive programs, local content, normative, productive, and self-development to produce productive, creative work. Vocational education aims to prepare graduates to be ready to work and innovate. The main purpose of this research is to know the content of the creative economy in shaping learners' life skills.
Battery Management System Design Using Buck–Boost Converter with PID Control: Desain Sistem Manajemen Baterai Menggunakan Buck–Boost Converter dengan Kendali PID R. Akbar Nur Apriyanto; Mohammad Erik Echsony; Ibra Satriatama; Andhika Putra Widyadharma; Imam Junaedi; Adiratna Ciptaningrum; R. Gaguk Pratama Yudha; Rossanti Dwi Hapsari; Haykal Puguh Pratama
Jurnal Teknik Elektro dan Komputasi (ELKOM) Vol. 8 No. 1 (2026): Jurnal Teknik Elektro dan Komputasi (ELKOM)
Publisher : Universitas Muhammadiyah Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32528/elkom.v8i1.4213

Abstract

Sistem Manajemen Baterai (Battery Management System/BMS) merupakan komponen utama dalam menjaga efisiensi, keamanan, dan umur panjang baterai, khususnya pada aplikasi seperti kendaraan listrik dan sistem penyimpanan energi. Penelitian ini merancang BMS yang dilengkapi dengan Buck–Boost Converter berbasis kontrol Proportional-Integral-Derivative (PID) untuk mengoptimalkan kinerja baterai, dengan tujuan menghasilkan tegangan keluaran yang stabil sesuai dengan nilai referensi yang diinginkan. Konverter dirancang agar dapat beroperasi pada mode penurun tegangan (buck) maupun penaik tegangan (boost) sesuai dengan kondisi masukan, dan sistem dikembangkan menggunakan dua pendekatan kontrol: open-loop dan closed-loop. Hasil pengujian menunjukkan bahwa metode open-loop tidak dapat secara konsisten mencapai tegangan keluaran target sebesar 15 V, sehingga memerlukan penyesuaian duty cycle sebesar 5%, sedangkan metode closed-loop dengan kontrol PID berhasil mencapai error tegangan kurang dari 5%, yang menunjukkan kestabilan yang baik terhadap gangguan dan perubahan beban. Selain itu, penerapan kontrol PID pada konfigurasi Buck Converter berhasil menurunkan tegangan dari 18 V menjadi 15 V dengan error sekitar 3%.
Pelatihan Penggunaan Mesin Hybrid 3D Printer dan Laser Engraving pada CV. Ayyasy Multi Usaha Wicaksono, Rendi Pambudi; Widyadharma, Andhika Putra; Sudirman, Dirvi Eko Juliando; Setyawan, Sulfan Bagus; Shahab, Dahris; Sartika, Dyah Anggun
DIKEMAS (Jurnal Pengabdian Kepada Masyarakat) Vol 9 No 1 (2025)
Publisher : Politeknik Negeri Madiun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32486/dikemas.v9i1.843

Abstract

Industri manufaktur lokal menghadapi tantangan untuk terus berinovasi dan meningkatkan efisiensi guna bersaing dengan produk impor. Teknologi mesin hybrid 3D printer dan laser engraving memiliki potensi besar untuk mendukung upaya ini, dengan kemampuan meningkatkan produktivitas, akurasi, dan fleksibilitas produksi. Program pelatihan ini bertujuan untuk memperkenalkan dan melatih penggunaan mesin hybrid 3D printer dan laser engraving kepada CV. Ayyasy Multi Usaha, sebuah perusahaan manufaktur di Madiun. Melalui pelatihan ini, karyawan diharapkan dapat mengoperasikan mesin secara optimal, meningkatkan efisiensi dan kualitas produk, serta memperkuat daya saing perusahaan di pasar. Metode pelatihan meliputi pengenalan alat, praktik langsung penggunaan mesin, dan perawatan mesin. Hasil pelatihan menunjukkan peningkatan keterampilan teknis peserta dan potensi peningkatan efisiensi produksi di perusahaan. Program ini diharapkan dapat menjadi contoh untuk adopsi teknologi modern oleh usaha kecil dan menengah (UKM) dalam meningkatkan daya saing mereka di era industri 4.0..
Co-Authors A.A Gde Agung Anom Arie W Abdullah, Fachrul Rizky Adhiyoga Santosa Adiratna Ciptaningrum Agung Bagus S. Satyarsa Agung Wiwiek Indrayani Anak Agung Ayu Putri Laksmidewi Anak Agung Ayu Suryapraba Anak Agung Bagus Ngurah Nuartha Angelia Carolin Angga Dwi Saputra Anna Marita Gelgel Aria Wibawa Arimbawa, I Komang Ariswanda, I Gusti Agung Gede Belinda Orline Olivia Singgih Budaya, I Made Maha Candra Candra, Alamanda Clarissa Tertia Daniel Siagian de Liyis, Bryan Gervais Desak Ketut Indrasari Utami Devi, Gusti Ayu Putu Giti Livia Dewa Ngurah Suprapta Dewa Putu Gede Purwa Samatra Dian Rizki Fitria Dirvi Eko Juliando Sudirman Dwijo Anargha Sindhughosa Eric Hartono Tedyanto Eric Hartono Tedyanto ERIC HARTONO TEDYANTO Faldi Yaputra Florence Diana Thomas G, Gayathridayawasi Gitari, Ni Made Haditya, Yogi hakim, aulia el Haykal Puguh Pratama I Gusti Ngurah Ketut Budiarsa I Ketut Sumada I Komang Arimbawa I Made Jawi I Made Oka Adnyana I Made Oka Adnyana I MADE OKA ADNYANA I Made Pramana Dharmatika I Wayan Niryana Ibra Satriatama Ida Ayu Sri Indrayani Ida Ayu Sri Wijayanti Ida Bagus Kusuma Putra IGN Budiarsa Imam Junaedi Indrasari Utami, Desak Ketut Indrayani, I.A. Sri Juhanna, Indira Vidiari Kesanda, I Made Phala Ketut Widyastuti Kusmarini, Putu Elmamira Kusuma, Yohan Intan Laksmidwei, A A A Putri Lim, Demetria Jesica Limalvin, Nicholas Prathama Luh Made Mas Rusyati MADE OKA ADNYANA Made Oka Adnyana Mahadewi, Ni Putu Ayu Putri Mahmud, Ahmad Ulil Albab Nadia, Hana Jasmine Naomi Valencia Simbolon Ni Kadek Mulyantari Ni Ketut Candra Wiratmi Ni Luh Gede Yoni Komalasari, Ni Luh Gede Yoni Ni Made Dwita Pratiwi Ni Made Susilawathi Ni Made Wira Tania Astarini Ni Nyoman Ayu Dewi Ni Putu Sukarini, Ni Putu Nila Wahyuni Nugraha, Boya P, Sukarini Pramana, Nyoman Angga Krishna Pranitha, Putu Diva Pratiwi, Ni Made Dwita Priandwika, Muhammad Rifki Agung Pusaka, Semerdanta Putra IGN, Purna Putri Rossyana Dewi Putu Emilia Dewi Putu Indah Mahardika Putri R. Akbar Nur Apriyanto R. Gaguk Pratama Yudha Raka-Sudewi A. A. Rakhmad Gusta Putra Rendi Pambudi Wicaksono Richard Suherlim Rindha Dwi Sihanto Risky Ilona Saputra Rizaldy Pinzon Rossanti Dwi Hapsari Rumai, I Made Winarsa Sanjaya, Feliani Sartika, Dyah Anggun Setiawan, Okky Yani Shahab, Dahris Sofyan Faridi Sri Wijayanti, Ida Ayu Sudirman, Dirvi Juliando Sulfan Bagus Setyawan Suryamulyawan, Kadek Adi Susilawathi, Ni Made Sutama, I Komang Reno Sutantohadi, Alief Syah Putra, Muhammad Dio Tedyanto, Eric Hartono Tertia, Clarissa Thomas Eko Purwata Tini, Kumara Tresna Erawan, I Gusti Ngurah Agung Trisnawati, Sri Yenni Vania Rau, Chiquita Putri Wahyu Pribadi Widya Trio Pangestu Widyastuti, Ketut Witari, Ni Putu Y, Yudiyanta Yes Matheos Lasarus Malaikosa Yudha, R. Gaguk Pratama Yudhiatama, Galang Dafa Yuniarni, Ruth Sharon