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Journal : Health Notions

Bee Pollen Effect on Blood Glucose Levels in Alloxan-induced Male Wistar Rats Rahayu, Aprilia Nurcahyaning; Wirjatmadi, Bambang; Adriani, Merryana; M., Soenarnatalina; Winarni, Dwi; Hartiningsih, Sri
Health Notions Vol 2 No 1 (2018): January, 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (246.122 KB)

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a
The Effect of Dayak Onion Bulb-Stem (Eleutherine Palmifolia (L.,) Merr.) Extract on Blood Glucose Levels of Mouse Suffered Diabetes Mellitus Arwati, Niluh; Wijatmadi, Bambang; Adriani, Merryana; Meilanani, Soenarnatalina; Winarni, Dwi; Hartiningsih, Sri
Health Notions Vol 2 No 3 (2018): March 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (93.312 KB)

Abstract

Dayak onions (Eleutherine Palmifolia (L.) Merr.) bulb stem contains phtyochemical contents, which act as antidiabetic compounds, such as eleutherol, eleuthocide A, and eleutherinoside B, as well as antioxidant compounds, which include triterpenoid, poliphenol, and flavonoid. Dayak onions was able to be used as the antidiabetic, since it had the ability to lower the blood glucose level and prevent from the free radicals, thus supressing the oxidative stress condition. This research had purpose to analyze the effect of Dayak onions bulb-stem as antioxidant and anti diabetic drugs. The research used experimental method with the population in this research was 25 male white mice strain wistar. The concentration of Dayak onions bulb-stem extracts were 300mg.kgBW-1, 400mg.kgBW-1, and 500mg.kgBW-1. Data analysis used Tukey HSD Test with 95% of  significance degree and was continued using manova test (average group ratio test). The result showed that. the extract of Dayak onions bulb-stem had the antidiabetical and antioxidant activity, which could lower the blood glucose levels and malondialdehid on the male white mice strain Wistar with the optimum effective doze of 500 mg.kgBW-1.   Keywords: Dayak onions bulb-stem, Blood glucose level, Malondialdehid (MDA)
The Effect of Dayak Onion Bulb-Stem (Eleutherine Palmifolia (L.,) Merr.) Extract on Blood Glucose Levels of Mouse Suffered Diabetes Mellitus Niluh Arwati; Bambang Wirjatmadi; Merryana Adriani; Soenarnatalina Meilanani; Dwi Winarni; Sri Hartiningsih
Health Notions Vol 2, No 3 (2018): March
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (202.309 KB) | DOI: 10.33846/hn.v2i3.153

Abstract

Dayak onions (Eleutherine Palmifolia (L.) Merr.) bulb stem contains phtyochemical contents, which act as antidiabetic compounds, such as eleutherol, eleuthocide A, and eleutherinoside B, as well as antioxidant compounds, which include triterpenoid, poliphenol, and flavonoid. Dayak onions was able to be used as the antidiabetic, since it had the ability to lower the blood glucose level and prevent from the free radicals, thus supressing the oxidative stress condition. This research had purpose to analyze the effect of Dayak onions bulbstem as antioxidant and anti diabetic drugs. The research used experimental method with the population in this research was 25 male white mice strain wistar. The concentration of Dayak onions bulb-stem extracts were 300mg.kgBW-1, 400mg.kgBW-1, and 500mg.kgBW-1. Data analysis used Tukey HSD Test with 95% of significance degree and was continued using manova test (average group ratio test). The result showed that. the extract of Dayak onions bulb-stem had the antidiabetical and antioxidant activity, which could lower the blood glucose levels and malondialdehid on the male white mice strain Wistar with the optimum effective doze of 500 mg.kgBW-1.Keywords: Dayak onions bulb-stem, Blood glucose level, Malondialdehid (MDA)
Bee Pollen Effect on Blood Glucose Levels in Alloxan-induced Male Wistar Rats Aprilia Nurcahyaning Rahayu; Bambang Wirjatmadi; Merryana Adriani; Soenarnatalina M.; Dwi Winarni; Sri Hartiningsih
Health Notions Vol 2, No 1 (2018): January
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (246.122 KB) | DOI: 10.33846/hn.v2i1.85

Abstract

Bee pollen, as an active ingredient in diabetes mellitus (DM) prevention and treatment, is able to reduce oxidative reactions and to regenerate cells. This study aimed to determine bee pollen effect on blood glucose levels of rats which induced by alloxan. This study used a completely randomized design with Pre-Post Test design and Control Group design. The subjects were 25 male wistar rats which divided randomly into 5 groups: (1) negative control group (non-DM rats); (2) positive control group (DM rats without bee pollen); (3) P1 group (DM rats with 0.25 g/day bee pollen); (4) P2 group (DM rats with 0.63 g/day bee pollen); and (5) P3 group (DM rats with 1.25 g/day bee pollen). Alloxan inducing was used to cause rats under DM or hyperglycemic conditions. The data were analyzed by Manova test and Tukey HSD test. Statistical analysis showed that bee pollen effectively had an effect on decreasing fasting blood glucose (FBG) levels in treatment groups with 0.002. Differences test showed a difference between positive control group and treatment groups, but there was no difference between all treatment groups. However, the bee pollen dosage which giving the lowest average of FBG was 0.25 g on P1 group. Keywords: Bee pollen, Blood glucose level, Alloxan
Co-Authors 'Azizah, Annisa Cahya Abdul Hakim Muhsyi Adhisti, Raya Anandita Puspaning Adlina, Rediarta Nisa Agoes Soegianto Agus Supriyanto Ahimsa Buena Merpati Alfiah Hayati Alifah Hayati Almando Geraldi Amalia Nur Mashita Amany, Ashilla Nadiya Amir Amir Anggi Puspitasari, Marcela Ani Kusbandiyah Ani Kusbandiyah Anjar Tri Wibowo Annisa, Rully Aprilia Nurcahyaning Rahayu Arofah, Rifka Utami Arwati, Niluh Arwati, Niluh Ayu Setyaningrum Bambang Wirjatmadi Bima Cinintya Pratama Binti Yunaida Boon Chin Tan Defi Nurul Hayati Dewandaru, Rhis Ogie Dewi, Meylisa Kusuma Dicky Darmawan Dirgantari, Novi Eko Hariyanto Erillia, Titan Erlyn Nurul Fauziah fatimah Fatimah Fauziah, Erlyn Nurul Firdaus Auliya, Zahra Fitra Syafira, Revika Fitriati, Azmi Gilang Permana Hadi Pramono Hardiyanto Wibowo, Hardiyanto haryani, tri Havidz Cahya Pratama Hidayati, Farisa Nabila Hijrianti, Zora Lutvya Sabrina Husen, Saikhu Akhmad I.B. Rai Pidada Idqa Nurtri Bhakti Ilham Nuryana Fatchan, Ilham Nuryana Inggit Almira Inne Ninda Resita Intan Permata Putri Intan Permata Putri ISTUNING MA’UNAH Iwan Fakhruddin Iwan Fakhruddin Junairiah Junairiah Khaleyla, Firas Khoerul Mukromiin, Ramadhan Laila Oshiana Fitria Azizah Lestari, Lita I.D. Listijani Suhargo, Listijani M., Soenarnatalina Manikya Pramudya Marta Tania Gabriel Ching Cing, Marta Tania Gabriel Merryana Adriani Mochammad Affandi Mudjiyanti, Rina Muhammad Fajar Nabilatun Nisa Nabilla, Nithasya Nadya Abanty, Fahma Nadyatul Ilma Indah Savira Nazah, Nawalin Neti Mustikawati Ni Wayan Sukma Antari Nia Adiani Primarastri Nimatuzahroh, Nimatuzahroh Norwani, Norlia Mat Nurmajid, Difa Naufal Nurmayanti, Rani Pandansari, Tiara Pramurindra, Rezky Priyo, Tri Anggono Rahayu, Aprilia Nurcahyaning Resita, Inne Ninda Rosmanida S A Husein Said Akmala Saikhu Ahmad Husen Saikhu Akhmad Husen Salamun Salamun Salamun Salamun Salsabila, Syarifah Sarwan Adi Kusumo Septian Hary Kalqutny Setyadi, Edi Joko Sifa, Mufatih Ariska Sifananda Soenarnatalina M. Soenarnatalina Meilanani Soenarnatalina Meilanani, Soenarnatalina Sri Hartiningsih Sri Hartiningsih Sri Hartiningsih Sri Puji Astuti Wahyuningsih, Sri Puji Astuti Sri Wahyuni Sri Wahyuni Sri Wulan Manuhara, Yosephine Sugiarso, R. Djarot Sugiharto Sugiharto Suhariningsih Titan Erillia Tri Anggono Priyo Tri Nurhariyati Triana Safitri, Nadia Ufairanisa Islamatasya Ufairanisa Islamatasya Wijatmadi, Bambang Win Darmanto Y Sri Wulan Manuhara Yoan Asri Triantara Yosephine Sri Wulan Manuhara Zaidatul Khauliyah, Desi