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All Journal Molecular and Cellular Biomedical Sciences (MCBS) Jurnal Ilmu Kefarmasian Indonesia Jurnal Pengabdian Masyarakat (ABDIRA) Proceeding of Mulawarman Pharmaceuticals Conferences Jurnal Sains dan Kesehatan

Niken Indriyanti

Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Author-ID : 4295845

Aerospace Engineering Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Formulasi Sediaan Liniment Aromaterapi dari Minyak Atsiri Bunga Kenanga (Cananga odorata): Formulation of Liniment Aromaterapy of Essential Oil Cananga Flower (Cananga odorata) Ragil Sekar Ayuni; Dewi Rahmawati; Niken Indriyanti
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Cananga essential oil has potential as an antidepressant and a relaxant for the nervous system, containing a compound, namely linalool from the monoterpene. The innovation of topical pharmacy preparations with the active ingredient of cananga essential oil is a useful. The purpose of this study was to formulate cananga essential oil with concentrations used of 1%, 2% and 4%. The results showed that formulas I, II and III had met the physical quality evaluation. The results of the organoleptic test of the three formulations were in the form of a liquid, a characteristic odor of cananga flower along with eucalyptus oleum and a light yellow color. The results of the pH stability test obtained an average of 4.2 formulations, 4.9 formulations II and 5 formulations III. The homogeneity test results from formulations I, II and III obtained homogeneous results. The results of the anti-irritation test of formulations I, II and III did not cause irritation. The overall results of the preference test showed that the panelists preferred the liniment preparation at a concentration of 4%. Concluded that the formulation of liniment with the active ingredient of cananga essential oil produced preparations that met the physical characteristics and hedonic tests.

Kajian Efektivitas Pengobatan pada Pasien Stroke Iskemik di Instalasi Rawat Inap RSUD Nunukan: Study of Treatment Effectiveness in Ischemic Stroke Inpatients Instalation Nunukan Hospital Rida Wahda Maulida Tahir; Hifdzur Rashif Rija’i; Niken Indriyanti
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Ischemic stroke occurs due to obstruction of the blood vessels that supply the brain. Obstruction occurs due to increased fat lining the blood vessels or atherosclerosis. Atherosclerosis will cause cerebral thrombosis and cerebral embolism. This study aims to examine effectiveness of the use of drugs in ischemic stroke patients hospitalization at Nunukan Hospital. This study is a non-experimental study with a descriptive analysis design using medical record data collected retrospectively and the number of samples in this study was 70 patients. The sample selection of this research was using purposive sampling technique. The results showed tthe highest characteristics of ischemic stroke patients by gender were male (54.29%), based on age group 45-65 years (64.29%), based on diagnoses with comorbidities (64.70%), and the length of treatment the most occurred in 5-10 days (72.55%). The most used drugs single therapy for ischemic stroke are antiplatelet drugs, namely aspirin (28.57%) and the most used combination therapy is piracetam and citicoline (50%). The most frequent drug interactions were aspirin and clopidogrel (48.57%). While the accuracy of drug use includes the right indication (100%), the right drug (94.29%), the right dose (97.14%), and the right frequency (97.14%). Thus, it was concluded that the treatment of ischemic stroke at the inpatient installation the Nunukan General Hospital was effective.

Efektivitas Nutrisi Medik Berbahan Aktif Mengkudu dan Apel Manalagi Terhadap Penurunan Kadar Glukosa Darah: Efficacy of Medical Nutrition using Active compounds of Noni and Manalagi Apples to Reduce Blood Glucose Levels Selfia Selfia; Muhammad Faisal; Niken Indriyanti
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Noni (Morinda citrifolia L.) contains saponin compounds that work to stimulate insulin secretion from ?-pancreatic cells and manalagi apples (Malus sylvestris Mill.) contain pectin which functions to delay the emptying of food in the stomach, bind fatty acids and reduce macronutrient absorption which can cause decreased blood glucose levels. This study aims to prove that medical nutrition with active ingredients of noni and manalagi apples has effectiveness in reducing blood glucose levels, prove that doses of medical nutrition with active ingredients of noni and manalagi apple are effective for lowering blood glucose levels and prove a decrease in blood glucose levels 30 minutes after treatment. The research method used is quasi-experimental with the measurement of blood glucose levels pre-test and post-test using human test subjects. The research ethics protocol has been obtained with No. 71/KEPK FFUNMUL/EC/EXE/08/2021 from KEPK FF UNMUL. The results showed that the administration of medical nutrition with a dose of 126 g of noni and 200 g of manalagi apple and a dose of 63 g of noni and 100 g of manalagi apple was effective in reducing blood glucose levels, with an average decrease in blood glucose levels of 9,60 ± 7,47 mg/dL and 6,40 ± 3,91 mg/dL. It can be concluded that the most effective dose to reduce blood glucose levels is medical nutrition with a dose of 126 g of noni and 200 g of manalagi apples.

Formulasi Sediaan Masker Gel Peel Off dari Minyak Atsiri Sereh (Cymbopogon citratus): Formulation of the Preparation of Peel Off Gel Mask from Cymbopogon Citratus Essential Oil (Cymbopogon citratus) Annisa Annisa; Andi Tenri Kawareng; Niken Indriyanti
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Lemongrass (Cymbopogon citratus) is one of the essential oil producing plants known as Lemongrass oil with the main content of citral compounds. Lemongrass essential oil is known to have antioxidant activity. The antioxidant activity of lemongrass oil can be used for skin care in the form of a peel off gel mask. The purpose of this study was to formulate a peel off gel mask preparation from lemongrass essential oil (Cymbopogon citratus) and to know the results of the physical evaluation of the peel off gel mask. The peel off gel mask was made in three formulas with different concentrations of PVA, namely F1 (10%), F2 (13%), and F3 (16%). Physical evaluation tests include organoleptic tests, homogeneity, viscosity, pH, dispersion, and drying time. The peel off gel mask in the three formulas was obtained in the form of a thick gel, white in color, and had a characteristic lemongrass smell. The results obtained based on the physical evaluation showed that the three formulas had met the required standard parameters.

Evaluasi Kejadian Ikutan Pasca Imunisasi pada Peserta Vaksinasi di Puskesmas Teluk Dalam, Tenggarong Seberang: Evaluation of Adverse Events Following Immunization in Vaccination Participants at Teluk Dalam Tenggarong Seberang Community Health Center Renaldi Adi Saputra; Niken Indriyanti; Dewi Rahmawati
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 15 (2022): Proceeding of Mulawarman Pharmaceuticals Conferences (Proc. Mul. Pharm. Conf.)
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/mpc.v15i1.636

Studi Etnofarmasi Tanaman Berkhasiat Obat Pada Suku Paser Di Desa Samurangau Dan Desa Tepian Batang Kabupaten Paser: Ethnomedicinal Study on Medicinal Plants of Paser Tribe in Samurangau Village and Tepian Batang Village of Paser Regency Nabila Nur Rahma Hidayat; Putri Anggreini; Niken Indriyanti
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 16 (2022): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/mpc.v16i1.671

Informasi mengenai tanaman berkhasiat obat yang digunakan secara tradisional pada suku- suku di indonesia masih kurang dieksplorasi, salah satunya pada suku Paser Kalimantan Timur. Oleh karena itu, penelitian ini bertujuan untuk mendokumentasikan tanaman serta ramuan yang digunakan oleh masyarakat Suku Paser. Penelitian ini merupakan penelitian deskriptif dengan teknik purposive sampling dan snowball sampling yang dilakukan di desa Tepian Batang dan desa Samurangau, kabupaten Paser. Pengumpulan data dilakukan melalui wawancara secara terbuka dengan menggunakan kuisioner terstruktural. Penelitian dilanjutkan dengan survei, dokumentasi, identifikasi, dan studi literatur tanaman. Hasil penelitian diperoleh informasi mengenai 46 spesies tanaman dan 12 ramuan untuk mengobati 38 penyakit. Tanaman yang paling banyak direkomendasikan oleh penduduk suku paser adalah ombung (Blumea balsamifera (L.) DC) yang digunakan untuk mengobati batuk, demam, batuk berdahak dan diperuntukkan bagi wanita pasca melahirkan. Cara penggunaan tanaman herbal yang paling banyak adalah diminum (55%). Bagian tanaman yang paling banyak digunakan adalah daun (48%) dan yang paling sedikit adalah umbi (1%). Habitat tanaman yang digunakan paling banyak diperoleh dari hutan (53%) dan paling sedikit adalah dari tepi sungai (3%). Berdasarkan hasil studi etnofarmasi disimpulkan bahwa terdapat 46 spesies tanaman obat dan 12 jenis ramuan berkhasiat obat yang dapat menjadi dasar penemuan obat baru.

Laporan kasus: Asuhan Kefarmasian Penggunaan Obat Flu Anak: Case Report: Pharmaceutical Care of the Use of Common Cold Drugs on Pediatric Niken Indriyanti; Velita Rosari; Pabely Nahwan Maulana; Erika Heldina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 16 (2022): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/mpc.v16i1.680

Asuhan kefarmasian pada penggunaan obat flu anak sangat diperlukan supaya keluarga pasien bisa memberikan obat yang tepat kepada anaknya. Banyaknya informasi di internet maupun kebiasaan menggunakan obat tertentu menjadi masalah jika obat yang dipilih tidak sesuai dengan kondisi flu anak. Tujuan laporan kasus ini adalah menyajikan 3 kasus flu anak dengan gejala yang berbeda dan pilihan obat yang berbeda. Metode yang digunakan adalah pengambilan data secara prospektif kemudian dianalisis secara deskriptif. Hasil analisis pada tiga kasus yang disajikan menunjukkan ketepatan pemilihan obat dengan keluhan yang dialami pasien. Informasi obat yang cukup sangat membantu penggunaan obat tersebut saat diberikan oleh keluarga pasien di rumah. Hasil akhirnya adalah peningkatan kecepatan kesembuhan pasien secara efisien.

Skrining Fitokimia dan Aktivitas Antikoagulan Sari Buah Melon (Cucumis melo L) Secara In Vivo: Phytochemicals Screening and In Vivo Anticoagulant Activity of Melon Juice (Cucumis melo L) Raisa Fadilla; Arsyik Ibrahim; Niken Indriyanti
Jurnal Sains dan Kesehatan Vol. 5 No. 3 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i3.1805

Anticoagulants are drugs used to inhibit the development and enlargement of a blood clot. Melon is known to contain adenosime that function to stop clotting of blood cell chip. This study aims to identify secondary metabolites contained in melon juice, fruit juice identify anticoagulant activity in vivo melon, look for an effective dose melon juice as a potential anticoagulant and melon juice compared with aspirin. A total of 15 male mice were divided into 5 groups, i.e. groups of melon juice dose of 12.9 g/kg BW, melon juice dose group of 25.8 g/kg BW, melon juice dose group of 51.5 g/kg BW, positive control group and negative control group. The sample is given once a day orally and measured in hours to 3, 6 and 9 after administration. Anticoagulant effect was tested by using the parameters of bleeding time and coagulation time. The results showed that the melon juice dose of 12.9 g/kg BW, 25.8 g/kg BW and 51.5 g/kg BW may increase bleeding time and coagulation time. From these results it can be seen that the melon juice has anticoagulant activity. Based on statistical test is known that the variation of doses is very significantly affect on bleeding time and the coagulation time.Keywords : anticoagulant, melon juice, bleeding time, coagulation time Abstrak Antikoagulan adalah obat-obat yang digunakan untuk menghambat perkembangan dan pembesaran bekuan darah. Melon diketahui mengandung zat adenosine yang berfungsi menghentikan penggumpalan keping sel darah. Tujuan penelitian ini ialah untuk mengidentifikasi metabolit sekunder yang terkandung dalam sari buah melon, mengidentifikasi aktivitas antikoagulan sari buah melon secara in vivo, mencari dosis efektif sari buah melon sebagai antikoagulan dan potensi sari buah melon dibandingkan dengan aspirin. Sebanyak 15 ekor mencit jantan dibagi menjadi 5 kelompok, yaitu kelompok sari buah melon dosis 12,9 g/kg BB, kelompok sari buah melon dosis 25,8 g/kg BB, kelompok sari buah melon dosis 51,5 g/kg BB, kelompok kontrol positif, dan kelompok kontrol negatif. Pemberian bahan uji dilakukan sekali sehari secara oral dan diukur pada jam ke 3, 6 dan 9 setelah pemberian. Efek antikoagulan diuji dengan menggunakan parameter waktu pendarahan dan waktu koagulasi. Hasil menunjukkan bahwa sari buah melon dosis 12,9 g/kg BB, 25,8 g/kg BB dan 51,5 g/kg BB dapat meningkatkan waktu pendarahan dan waktu koagulasi. Dari hasil tersebut dapat diketahui bahwa sari buah melon memiliki aktivitas antikoagulan. Berdasarkan uji statistik, diketahui bahwa variasi dosis berpengaruh sangat signifikan terhadap waktu pendarahan dan waktu koagulasi. Kata Kunci: antikoagulan, sari buah melon, waktu pendarahan, waktu koagulasi

Co-Authors Afrillia Nuryanti Garmana Agata Tika Sari Akhmad Ifda Hanip Alexander Mansyuria Almeida, Maria Andi Asti Ainun Andi Tenri Kawareng Annisa Annisa Antadini Antadini Arsyik Ibrahim Asri Dwi Endah Dewi Pramesthi Bella Sasmiyandri Debby Putri Mutiara Yusuf Dewi Mayasari Dewi Rahmawati Dewi Rahmawati Dewi Rahmawati Elin Yulinah Sukandar Eni Ayu Putri Erika Heldina Erwin Samsul Fahriani Istiqamah Jafar Fika Aryati Fika Aryati Frety Aula Nur Islamika Hafifah Sarwanda Hajrah Hajrah Hajrah Hajrah Halimathussadiah Halimathussadiah Halimatusya’ Diah Hifdzur Rashif Rija’i I Ketut Adnyana Indah Puspitasari Joewono Soeroso JOEWONO SOEROSO Jorgi Imanuel Emor Jufriyanto Pasang Junaidi Khotib Kiki Fitria Anggraeni Kiki Riski Amelia Andi Kornelius Yustico Trimedya Purba Maharani Adelia Zeline Maria Saena Puru Meilanie Dwi Anggraeni Meilina Purnama Ningrum Mirhansyah Ardana Muhammad Faisal Mukti Priastomo Nabila Nur Rahma Hidayat Nilam Sari Nur Aini Buring Incau Nur Masyithah Z Nur Masyithah Zamruddin Nur Masyithah Zamruddin Nur Mita Nurul Fitriani Nurul Syafitri AR Pabely Nahwan Maulana Pabely Nahwan Maulana Pakendek Fefryani Putri Anggreini Ragil Sekar Ayuni Raisa Fadilla Renaldi Adi Saputra Rida Wahda Maulida Tahir Risna Agustina Rolan Rusli Sabaniah Selfia Selfia Suparningtyas, Juniza Firdha Tiya Nur Aini Velita Rosari VICTORIA YULITA FITRIANI Vita Olivia Siregar Widya Vergiana Oktrinorma Wilujeng Ayu Wisnu Cahyo Prabowo

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