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Journal : Journal Of Health Science Community

Association between Soluble Transferrin Receptor with Central Obesity Muh Taufiq; Liong Boy Kurniawan; Mansyur Arif
Journal of Health Science Community Vol. 2 No. 3 (2022): February
Publisher : Universitas STRADA Indonesia

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Abstract

Subclinical chronic inflammation in central obesity theoretically leads to hepcidin synthesis in large amount, which inhibits iron absorption and inhibits the release of iron stores from macrophages. This subsequently leads to an increase in soluble transferrin receptor (sTfR) levels due to inadequate cellular iron. This study aims to determine the association between sTfR levels with central obesity. The study design was cross sectional with 75 subjects selected purposively. The sTfR level was determined using ELISA technique. Descriptive statistical method and bivariate analysis were employed to determine the association between these variables. The results showed that there was a significant difference in terms of sTfR levels of central obese individuals with those of non-central obese one. In line with this finding, waist circumference also exhibited a positive correlation with sTfR levels. In addition, we found no systematic relationship between gender and age with respect to sTfR levels. From these results, it was concluded that the sTfR levels were higher in subjects with central obesity compared to non-central obesity, and the greater the waist circumference, the higher the sTfR levels.
Co-Authors Adnan, Endy Afandi, Ichlas Nanang Aminuddin Aminuddin Anaam, Andi Khairul Andi Alfian Zainuddin Andi Munawirah Ani Kartini Arif Santoso Ariyandy, Andi Asvin Nurulita Asvin Nurulita Basri, Muhammad Iqbal Chika Pratiwi Darmawati E R Darmawaty ER Darmawaty ER, Darmawaty Darmawaty Rauf Darwati Muhadi Darwati Muhadi Esa, Tenri Fadillah, Ismirayanti Fitriani Mangarengi Fitriani Mangarengi FITRIANI MANGARENGI, FITRIANI Fitry Hamka Gustamin Gustamin Habibah S. Muhiddin Hardyansa Hasna, Hasna IRFAN IDRIS Kasimat, Maria Magdalena Mansyur Arif Mansyur Arif Mansyur Arif Mansyur Arif Mansyur Arif Martina Rentauli Megawati - Moonika Todingan Muh Taufiq Muh Taufiq Muhammad Fachrul Hidayat Mulyamin, Winda Mustakin Mustakin Mutiah Dwi Humairah Muyadhil Nurindar Nadhifah, Naurah Nurahmi Nurahmi Nurahmi Nurahmi Nurahmi Nurahmi Nurahmi Nurahmi Nurahmi Nurahmi, Nurahmi Nurhayana Sennang Nurhayana Sennang, Nurhayana Nuril Sofiantin Oktarina, Nur Hasni Pratiwi, Chika Putri Hidayasyah Purnama Lestari Putri Hidayasyah Purnama Lestari R Satriono Rachmawati Muhiddin Rafiah, Sitti Ratna Dewi Artati Rauf, Darmawaty Ruland DN Pakasi Ruland DN Pakasi Ruland DN Pakasi Ruland DN. Pakasi Samad , Raehana Sheridan, Sabilla Sri Anita Suci Aprianti suci aprianti sukmawaty - Surur, Andi Ainun Zulkiah Suryani Jamal Syafaat, Andi Wali Tenri Esa Uleng Bahrun Uleng Bahrun Uleng Bahrun Uleng Bahrun, Uleng Wali Syafaat, Andi Wandani Syahrir Widaningsih, Yuyun Yunita Rapa Yunita Rapa' Yunita Rapa' Yustisia, Ika Yuyun Widaningsih