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Quality of Life of COVID-19 Pfizer® Booster Vaccine Recipients Using Short Form-8 Instrument in Palu City Adisaputra, Arya Dibyo; Amelia Rumi; Khusnul Diana; Salza Syahdianti Rahmadani
Jurnal Ilmu Farmasi dan Farmasi Klinik Vol. 23 No. 1 (2026): Jurnal Ilmu Farmasi dan Farmasi Klinis (JIFFK)
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/jiffk.v23i1.14117

Abstract

The COVID-19 pandemic continues, and vaccination initiatives are still underway. Booster vaccinations are administered to enhance antibodies that decline after several months of receiving the primary vaccine doses. It is important to understand the impact of these vaccinations on recipients' quality of life. This study aims to examine the influence of demographic and clinical characteristics on the quality of life of the population in Palu City who received the Pfizer® COVID-19 booster vaccine. This research is an observational, cross-sectional study. The sampling was conducted using the consecutive sampling method, and a total of 400 individuals who met the inclusion criteria were included as the sample. This study used the Short Form-8 questionnaire to assess quality of life. Data analysis was performed using multiple linear regression. The study found that the quality of life of individuals who received the Pfizer® COVID-19 booster vaccine in Palu City was good, as evidenced by average domain scores≥50. An individual's quality of life can be assessed in terms of physical and mental aspects. Post-vaccination symptoms and a history of COVID-19 infection (p<0.05) influenced the physical aspect. Age, occupation, and a history of COVID-19 infection (p<0.05) influenced the mental aspect. The quality of life of the population in Palu City who received the Pfizer® COVID-19 booster vaccine showed a greater improvement in mental health than in physical health.
Quality of Life of Outpatients with Type 2 Diabetes Mellitus at Anutapura Hospital Diana, Khusnul; Azizah, Vina Miftahul; Hardani, Muhammad Fakhrul; Tandah, Muhamad Rinaldhi
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 11 No. 1 (2026)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v11i1.44208

Abstract

Type 2 Diabetes Mellitus (T2DM) is a chronic disease that may reduce health-related quality of life (HRQoL) because of long-term treatment complications. This study assessed HRQoL among T2DM outpatients at Anutapura Hospital and examined whether the overall HRQoL profile differed by medication group after adjustment for selected patient characteristics. A hospital-based cross-sectional study was conducted at the Internal Medicine Outpatient Clinic of Anutapura Hospital, Palu, Indonesia, from October to December 2024. Using non-probability sampling, 92 adults with T2DM were enrolled and classified into three medication groups: monotherapy oral antidiabetic drugs (OADs), combined OADs, and insulin. HRQoL was measured using the Diabetes Quality of Life Clinical Trial Questionnaire-Revised (DQLCTQ-R), which includes eight domains scored on a 0–100 scale, with higher scores indicating better HRQoL. Internal consistency was acceptable (Cronbach’s alpha = 0.82). Because several domains did not meet normality assumptions, the overall HRQoL profile was analyzed using PERMANOVA. Most respondents were female, aged 41–60 years, and had diabetes duration of less than 5 years. Across medication groups, Physical Function showed the highest scores, whereas Treatment Satisfaction tended to be the lowest. In the adjusted PERMANOVA model, medication group was not significantly associated with the overall HRQoL profile (F = 0.81, p = 0.521, R² = 0.014). In contrast, age (p = 0.016), occupation (p = 0.008), and duration of illness (p = 0.001) were significantly associated with the combined HRQoL profile. These findings suggest that HRQoL differences were more strongly related to patient characteristics than to medication group alone.