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All Journal Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT JURNAL FARMASIMED (JFM) PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Riset Kefarmasian Indonesia Community Development Journal: Jurnal Pengabdian Masyarakat Madaniya Indonesian Journal of Chemical Science and Technology Jurnal Farmasi dan Sains Indonesia (JFSI) Jurnal Pengabdian Masyarakat (ABDIRA) Jurnal Farmasi Klinik dan Sains Jurnal Pengabdian West Science FARMASAINKES Journal of Pharmaceutical and Sciences. E-Amal: Jurnal Pengabdian Kepada Masyarakat
Yayuk Putri Rahayu
Department Of Pharmacy, Universitas Muslim Nusantara Al Washliyah
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Journal : JURNAL FARMASIMED (JFM)

 1 
ANTIBACTERIAL TEST OF ETHANOLIC EXTRACT NANOPARTICLES FROM ARUM MANIS MANGO LEAVES (MANGIFERA INDICA L. VAR. ARUM MANIS) AGAINST STAPHYLOCOCCUS AUREUS Lubis, Nadya Frestika; Rahayu, Yayuk Putri; Nasution, Haris Munandar; Lubis, Minda Sari
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1687

Abstract

Secondary metabolites with antibacterial properties have been found in arummanis mango leaves. Alkaloids, flavonoids, tannins, saponins, triterpenoids, and steroids, especially the mangiferin molecule found in several mango varieties, are also present in arum manis mango leaf extract. Mangiferin has shown action on Staphylococcus aureus as an antibacterial agent that can prevent the development of bacteria. Staphylococcus aureus is one of the bacteria that triggers skin infections. In this research, extract nanoparticles and inhibition tests against staphylococcus aureus bacteria were prepared using extract nanoparticles and ethanol extract of arum manis mango leaves. The manufacture of nanoparticles in this study was carried out because smaller and nanometer-sized materials have more special chemical and glass characteristics; their small size has a greater surface area to volume ratio than larger particles. Nanoparticles are small particles ranging in size from 1 to 1000 nm. A particle size analyzer is used to characterize nanoparticles. Using the disc diffusion method, antibacterial activity tests were carried out at concentrations of 25%, 50%, and 75%, using nanoparticle extracts, and 2.5%, 5%, and 7.5% for extract concentration. The results of the extract nanoparticle size characterization were 40.2 nm. The bacterial inhibition zones of arum manis mango leaf extract obtained at concentrations of 25%, 50%, and 75% were 11.9, 14.4, and 15.4 mm, respectively. Meanwhile, the inhibition zones of nanoparticle bacteria extract 2.5%, 5%, and 7.5% were 15.5, 17.5, and 18.3 mm, respectively. The concentration of 2.5% nanoparticle extract has the inhibition power of bacteria equivalent to that of 75% ethanol extract, so it says that the nanoparticles can reduce the size dose and have an inhibition power in the moderate sensitivity category.
Co-Authors Adelia Ramadani Adelia Ramadani Adli Nuzula Rahmah Alfi Wahyudi Nasution Amaliana, Amaliana Anny Sartika Daulay Anny Sartika Daulay Anny Sartika. D Ayu , Tri Indah Pagar Barutu, Liza Anisa Shevia Cindy Widya Rosa Br Simarmata D Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang Delvi Amira Hutagaol Dena, Mutia Diana Sopha Dikki Miswanda Elma Natasya Fatikasari, Cilki Fithri Pulungan, Ainil Fitri Mulyani, Fitri Gabena Indrayani Dalimunthe Gultom, Syarifah Elena Habibie, Dian Halim, Rahman Harahap, Azmi Kurniawan Harahap, Siti Salimah Haris Munandar Nasution Hendri Gunawan Hutagaol, Delvi Amira Huzeila Nisa Siregar Ika Fitriani Ika Yeni Siahaan Khofifah , Nur Lailatulqodri, Najwa Lastri Afni Leni Safriani Linda, Rosa Lisda Mayanti Lubis, Minda Sari Lubis, Nadya Frestika Lulu Ilma Khoirun Nissa M Pandapotan Nasution M Pandapotan Nasution M. Pandapotan Nasution M. Pandapotan Nasution Merani Phaustina Lumban Gaol Muhammad Amin Nasution Muhammad Arif Muhammad Hizbullah Muhammad Pandapotan Nasution Munaziatul Jannah Nadia Salsabilla Nanda Nadia Nasution , Muhammad Amin Nasution, M. Pandapotan Nelsa Fahira Nofa Lismandaria Nomi Noviani Novi Yuliandari Novika Utami Novriani Putri Santia Nurul Hasanah Oca Putri Nazuhra Oktavia, Sri Rahayu Prasetyo , Healthy Aldriany Rafita Yuniari Rafita Yuniart Ridwanto Ridwanto Rosalinda Mahdalena Sinaga Rosalinda Mahdalena Sinaga Rossa, Aliffa Safira , Liyuza Selfiani Selfiani Sepriani, Ananda Shilvia, Fatin Silitonga, Burju Artha Marshalina Sinaga, Rosalinda Mahdalena Siregar, Ahmad Gozali Siti Aisyah Jamil Sony , Suyefri Sri Wahyuni Supiyani, Supiyani Syahni, Cynthia Syarifah Elena Gultom Tawir Rina Rezeki Tusaddiah, Ria Winata, Ageng Tegar Yani, Farida Yayuk Yuliana Yuniarti, Rafita Zulmai Rani