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All Journal Nurse Media Journal of Nursing Jurnal Biologi Tropis Jurnal Pengabdian Magister Pendidikan IPA Jurnal Pelayanan dan Pengabdian Masyarakat (Pamas) ad-Dawaa : Journal of Pharmaceutical Sciences Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Kesehatan Tambusai Jurnal Abdimas Sangkabira Sasambo Journal of Pharmacy INDRA: Jurnal Pengabdian kepada Masyarakat TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora Jurnal Katalisator Benzena Pharmaceutical Scientific Journal Parapemikir Jurnal Ilmiah Farmasi CERATA Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan
Eskarani Tri Pratiwi
Program Studi Farmasi, Fakultas Kedokteran Dan Ilmu Kesehatan, Universitas Mataram
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Optimization of Cream Formula Extract Sargassum Crassifolium Using Varied Concentrations of Glyceryl Monostearate and Triethanolamine Emulgators With The Simplex Lattice Design Method Utari, Weny Syafitri; Pratiwi, Eskarani Tri; Subaidah, Windah Anugrah; Ridwan, Sucilawaty
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.9970

Abstract

Sargassum sp. contains bioactive compounds in the form of phenols that have the potential as sunscreen agents in the ultra category, namely 33.2 ± 3.11. The most commonly used formulation for sunscreen products is cream. The purpose of this study was to determine the optimal concentration of glyceryl monostearate and triethanolamine as emulsifiers for Sargassum sp. extract cream, as well as to investigate the physical properties of the optimal Sargassum sp. extract cream formulation. Optimization of the cream formulation was carried out using the Simplex Lattice Design method with Design Expert 13 software, resulting in 8 formulations. The optimal formula obtained was then subjected to physical evaluation, including organoleptic evaluation, homogeneity, and emulsion type. Data analysis used the one-sample t-test method in SPSS version 25. The yield of Sargassum sp. extract was 7.37%. The optimization results showed that the optimal concentration was 7.6% glyceryl monostearate and 0.5% triethanolamine. The optimal cream formulation has good physical properties, namely a soft semi-solid texture, light green color, homogeneity, oil-in-water cream type, pH value of 7.64±0.03, viscosity of 7.626±261.02 cP, adhesive power of 4.37±0.06 seconds, and spreadability of 6.3±0.11 cm. The results of the one-sample t-test statistical analysis of the physical properties of the optimal formulation showed no significant difference from the predicted results, with a confidence level (p>0.05).
Pendampingan Pengolahan Limbah Kulit Pisang Menjadi Sabun Cuci Piring Bagi Kelompok Usaha Waroh Maju Bersama Di Desa Sesaot Lombok Hasbi, Nurmi; Eskarani Tri Pratiwi; Nisa Isnaeni Hanifah; Rosyunita; Ni Wayan Puspa Wijaya Suryantarini; Syahrani Febriyanti; Muthiah Ramadhani
Jurnal Pengabdian Magister Pendidikan IPA Vol 8 No 3 (2025): Juli-September 2025
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v8i3.12853

Abstract

Community service activities were carried out in Sesaot Village, Narmada District, West Lombok Regency, which is known as a banana production center with a fairly large production volume on Lombok Island. One of the processing groups is Usaha Waroh Maju Bersama, which is engaged in the production of banana-based souvenirs, such as banana chips, banana sale, and various other processed products. However, this processing activity produces banana peel waste that has so far been thrown away. In fact, banana peels contain phytochemical compounds such as saponins and flavonoids that have the potential to be used as antibacterial agents. This community service aims to provide assistance to Usaha Waroh Maju Bersama to process banana peel and lime waste into antibacterial dishwashing soap. This activity was carried out on Friday, August 8, 2025. The service method used was mentoring through demonstrations. This activity was attended by 11 participants, all of whom were women, the majority aged 26-50 years. The educational background of the participants varied, dominated by junior high and high school graduates. The evaluation results showed a positive response: 81.8% of participants strongly agreed that the material was easy to understand, 90.9% considered the resource person to have delivered the material clearly, and 72.7% felt the practice was easy to follow. No participants disagreed, so it can be concluded that the activity was effective. Participants said that the steps for making soap were quite simple, practical, and easy to apply at home. Most participants expressed a desire to participate in follow-up activities with different topics such as making skin care products from natural ingredients or utilizing other fruit waste. This community service activity succeeded in increasing community skills and awareness in processing banana peel waste into healthy, environmentally friendly, and economically valuable household products.
The Risk of Diabetic Peripheral Neuropathy among Patients with Type 2 Diabetes Mellitus in Urban and Rural Areas Qona'ah, Arina; Pratiwi, Ika Nur; Pawanis, Zulfayandi; Yamani, Laura Navika; Pratiwi, Eskarani Tri; Nursalam, Nursalam; Ramoo, Vimala
Nurse Media Journal of Nursing Vol 15, No 2 (2025): (August 2025) [In Progress]
Publisher : Department of Nursing, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/nmjn.v15i2.56936

Abstract

Background: Diabetic Peripheral Neuropathy (DPN) is a common complication of type 2 diabetes mellitus (T2DM) and is closely linked to poor glycemic control. However, little is known about how environmental and lifestyle differences between urban and rural settings affect the risk of DPN.Purpose: This study aimed to identify and compare the risk factors of DPN among T2DM patients living in rural and urban areas.Methods: A comparative cross-sectional design with purposive sampling was used to recruit 156 T2DM patients from both urban (Surabaya) and rural (Lamongan) areas of East Java, Indonesia. Data were collected using the Vascular Quality of Life-6 (VQ-6), Diabetic Neuropathy Symptom (DNS), Diabetic Neuropathy Examination (DNE), and Ankle-Brachial Index (ABI). Logistic regression was performed, with a significance level set at p<0.05.Results: The mean age of rural participants was 55.8 years, slightly younger than that of urban participants. Urban residents had higher levels of education (37.7%) but engaged less in regular physical activity (51.9%). The risk of DPN differed significantly between rural and urban participants. Vascular function (ABI, OR = 4.526, range = 0.7–4.00), peripheral nerve symptoms (DNS, OR = 2.838, range = 0–2), neurological deficits (DNE, OR = 1.571, range = 0–5), and neuropathy-related quality of life (VQ-6, OR = 0.663, range = 0–24, p=0.020) were more pronounced among rural participants.Conclusion: Rural T2DM patients are at greater risk of DPN due to vascular and neuropathic complications, combined with sociodemographic disadvantages. These findings highlight the importance of early detection and tailored education programs for rural communities to prevent and manage DPN.
Uji Antiinflamasi Ekstrak Etanol Ashitaba (Angelica keiskei) Secara In Vitro Fitriana, Mariama; Hajrin, Wahida; Subaidah, Windah Anugrah; Ridwan, Sucilawaty; Pratiwi, Eskarani Tri
Jurnal Biologi Tropis Vol. 24 No. 2b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i2b.8105

Abstract

Angelica keiskei has potential as an anti-inflammatory agent because it contains chalcone which has been proven to be able to suppress inflammation through inhibiting nitric oxide production and inhibiting the expression of the iNOS and COX-2. The anti-inflammatory potential of Angelica keiskei needs to be tested. This study aimed to determine the anti-inflammatory activity of Angelica keiskei ethanol extract using the protein denaturation inhibition method. Angelica keiskei was extracted using the sonication method with 96% ethanol. The extract was tested for anti-inflammatory activity using the protein denaturation inhibition method with diclofenac sodium as a positive control. The percent of inflammatory inhibition is used to assess sample activity. The results showed that the percent of inflammatory inhibition of Angelica keiskei ethanol extract increased as the test concentration increased. The maximum percent inhibition was obtained at a concentration of 1.5% with the percent of inflammatory inhibition value of 23.14% ± 0.05. Angelica keiskei ethanol extract has anti-inflammatory activity based on in vitro testing using the protein denaturation inhibition method.
Formulation and Evaluation of Moringa Leaf Ethanol Extract Emulgel and its Effectiveness Test Against Staphylococcus aureus Raissa, Talitha Hasna; Pratiwi, Eskarani Tri; Hidayati, Agriana Rosmalina
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.8218

Abstract

Moringa leaves (Moringa oleifera Lamk.) have Tannin compounds which are secondary metabolites as antibacterial. The purpose of this study is to determine the antibacterial properties of ethanol extract from moringa leaves against Staphylococcus aureus. The research methods began with the extraction of Moringa leaves using sonication with 96% ethanol as the solvent, followed by testing the antibacterial effectiveness of the extract at concentrations of 5%, 10%, and 20%. The extract concentration with the best inhibition zone diameter was formulated into an emulgel, followed by physical evaluation of the formulation and testing its effectiveness against Staphylococcus aureus. The bacterial inhibition zone was measured to determine the antibacterial level of the extract and emulgel formulation. The results of antibacterial effectiveness were evaluated using the One Way ANOVA test with a confidence level of 95%. The yield of the extract was found to be 13.05%. The inhibition zone diameters for the ethanol extract of Moringa leaves at concentrations of 5%, 10%, and 20% were 4.8 mm, 5.3 mm, and 8.1 mm, respectively. The physical evaluation of the ethanol extract emulgel formulation met the criteria for a good emulgel. The emulgel containing 4% ethanol extract from Moringa leaves produced an inhibition zone diameter of 4.8 mm, indicating weak antibacterial effectiveness. There was a significant difference between the treatment groups according to the results of the One Way ANOVA test with a significance value (p=0.000). This study found that Moringa oleifera leaf ethanol extract has the ability as an antibacterial; however, its effectiveness decreases when formulated into an emulgel, likely due to the reduction in extract concentration in the final formulation.
Optimization of Eye Shadow Powder Formula Preparation of Buni Fruit Extract (Antidesma bunius L. Spreng) as Natural Dye Lestari, Neli Aulia; Hajrin, Wahida; Pratiwi, Eskarani Tri
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10140

Abstract

The use of synthetic dyes in cosmetics can cause side effects such as allergies. Therefore, the presence of natural dyes such as anthocyanins from berries is a safer alternative for the community. However, the stability of anthocyanins as natural dyes can be affected by pH. The purpose of this study was to determine the optimum concentration of citric acid and tartaric acid in eyeshadow powder preparations as pH stabilizers using the Simplex Lattice Design method. The research method used the sonication method. Then, the formulation results from running SLD were carried out and evaluated for particle size, adhesiveness, and pH. Data analysis used SLD to obtain the optimum formula. Then, the evaluation was carried out as before with additional evaluations of organoleptic tests, homogeneity and polish. Furthermore, the data were verified statistically with a one-sample t-test. The results obtained an extract yield of 22.9% and a positive anthocyanin content. Based on the SLD method, the optimum formula was obtained with a citric acid concentration of 1.49% and a tartaric acid concentration of 0.508%. Verification of the optimum formula showed no significant difference between the experimental response and the predicted response with a pH value of 5.75 ± 0.12; adhesive power of 11.66 ± 1.52%; and particle size of 126.32 ± 2.02 μm. The conclusion is that the optimum formula produces good physical characteristics and the verification results show agreement between the predicted response and the experimental results.
ANALISIS KANDUNGAN SENYAWA MINYAK ATSIRI DARI LIMBAH KULIT JERUK PERAS (CITRUS SINENSIS L.) MENGGUNAKAN METODE GC-MS Khalila Fitri, Maulida; SetyowatiSriwidyasari, Ni Luh Ayu; Setyowati, Kirana Ayu; Salam, Mahra Murniati; Yustitia, Nur Tahany; Tri Pratiwi, Eskarani
Jurnal Kesehatan Tambusai Vol. 5 No. 1 (2024): MARET 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i1.25788

Abstract

Kulit jeruk peras (Citrus sinensis L.) merupakan salah satu limbah organik yang menumpuk dan belum dimanfaatkan secara intensif. Pada umumnya limbah kulit jeruk peras tersebut hanya dibuang begitu saja dan menjadi limbah organik yang memiliki aroma kurang menyenangkan, padahal kulit jeruk tersebut memiliki kandungan senyawa yang berkhasiat seperti salah satu yang paling dominan yaitu minyak atsiri. Minyak atsiri memiliki berbagai kandungan yang bermanfaat dalam bidang kesehatan yaitu diantaranya sebagai aromaterapi dan antibakteri. Berbagai kandungan yang ada pada minyak atsiri dapat diidentifikasi menggunakan metode GC-MS. Metode GC-MS sendiri memiliki keuntungan yaitu waktu identifikasinya cepat, memiliki sensitifitas yang tinggi, pemisahan yang baik, dan alat dapat dipakai dalam waktu lama. Metode ini juga digunakan karena komposisi minyak atsiri bersifat volatil (mudah menguap) sehingga senyawa tersebut dapat dielusikan dengan gas. Sebanyak 200 gram kulit jeruk peras di destilasi selama 5 jam. Penelitian ini dilakukan dengan menggunakan metode destilasi air untuk menghasilkan minyak atsiri yang kemudian dilakukan analisis menggunakan GC-MS. Hasil analisis GC-MS minyak atsiri kulit jeruk yaitu terdapat 10 peak senyawa diantaranya Alpha pinene, Beta.-Phellandrene, 1-beta-pinene, Beta-myrcene, Octanal, Limonen, Linalool, 3-Cyclohexen-1-methanol, .alpha, Decanal, dan 1,2-Benzenedicarboxylic acid. Dari 10 senyawa tersebut, senyawa limonen menjadi senyawa yang paling dominan yang terkandung dalam minyak atsiri kulit jeruk peras
FORMULASI DAN UJI EFEKTIVITAS SEDIAAN INHALER STICK DARI LIMBAH KULIT JERUS PERAS (CITRUS NOBILIS) Murniati Salam, Mahra; Pratiwi, Eskarani Tri; Widyasari, Ni Luh Ayu Sri; Setyowati, Kirana Ayu; Fitri, Maulida Khalila; Yustitia, Nurtahany
Jurnal Kesehatan Tambusai Vol. 5 No. 3 (2024): SEPTEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i3.33037

Abstract

Hidung tersumbat merupakan gejala utama dari penyakit rinitis alergi. Obat-obatan yang diindikasikan untuk meringankan hidung tersumbat memiliki efek samping seperti mengantuk, gangguan saluran pencernaan dan terkadang membuat mulut terasa kering. Kulit jeruk memiliki kandungan limonen yang berpotensi sebagai efek dekongestan hidung tersumbat. Salah satu sediaan farmasi yang dapat diaplikasikan yaitu inhaler stick. Tujuan penelitian untuk mengembangkan produk inhaler stick dari limbah kulit jeruk peras (Citrus nobilis) yang dapat meringankan gejala hidung tersumbat. Penelitian ini dilakukan menggunakan metode eksperimental dengan pembuatan ekstrak kulit jeruk yang diuji secara in vivo pada hewan mencit dan manusia. Hasil uji in vivo pada mencit menunjukkan bahwa efek dekongestan pada penurunan bobot mencit inhaler vicks dan sediaan inhaler stick kulit jeruk peras tidak berbeda signifikan (p  0,1) dengan kontrol positif. Penurunan bobot mencit disebabkan oleh efek obat pada beberapa organ mencit dan berkurangnya lendir atau cairan dari dalam tubuh mencit. Sedangkan pada uji in vivo 12 manusia sebagai responden menghasilkan 100% responden tidak mengalami efek samping mual/muntah dan gatal setelah penggunaan sediaan inhaler stick kulit jeruk peras. Sedangkan 75% responden dari aroma khas, 67% responden dari efek melegakan dan 25% responden dari tampilan sangat setuju bahwa sediaan inhaler stick kulit jeruk peras dapat menjadi sediaan alternatif inhaler untuk melegakan hidung tersumbat.  
Tingkat Pengetahuan Siswi Pondok Khusus Putri Al-Halimy Tentang Kosmetika Ilegal Manafe, Deary Pretty Genovani; Puspitasari, Candra Eka; Pratiwi, Eskarani Tri
Jurnal Pengabdian Magister Pendidikan IPA Vol 6 No 4 (2023): Oktober-Desember 2023
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v6i4.5684

Abstract

Kosmetika adalah sediaan farmasi/paduan bahan yang digunakan pada bagian luar badan dengan tujuan untuk membersihkan, menambah daya tarik, mengubah penampilan melindungi supaya dalam keadaan baik, memperbaiki bau badan, tetapi tidak dimaksudkan untuk mengobati atau menyembuhkan penyakit. Kosmetika ilegal adalah kosmetika yang tidak memiliki izin peredaran karena tidak memenuhi standar produk kosmetik. Remaja merupakan keompok rentan terpapar kosmetika ilegal karena remaja memiliki kecenderungan senang bereksplorasi dengan mencoba berbagai jenis produk kosmetika. Kegiatan ini bertujuan untuk memperoleh gambaran tingkat pengetahuan siswi Pondok Khusus Putri Al-Halimy Kabupaten Lombok Barat tentang kosmetika ilegal. Metode yang digunakan adalah penyuluhan dan pembagian kuesioner yang telah divalidasi. Pada kegiatan ini, diperoleh gambaran pengetahuan siswi tentang kosmetik ilegal sebelum penyuluhan dengan nilai rata-rata 70,72. Setelah penyuluhan, terjadi peningkatan nilai rata-rata responden sebesar 9,13% menjadi 77,18. Berdasarkan hal ini, dapat dikatakan bahwa penyuluhan yang dilakukan meningkatkan pengetahuan siswi Pondok Khusus Putri Al-Halimy tentang kosmetika ilegal.
Sosialisasi Terapi Swamedikasi Akupresur Dan Inhalasi Minyak Wangi Untuk Mengurangi Gejala Pilek Pada Siswa SDN 02 Terong Tawah Setyowati, Kirana Ayu; Widyasari, Ni Luh Ayu Sri; Salam, Mahra Murniati; Fitri, Maulida Khalila; Yustitia, Nur Tahany; Pratiwi, Eskarani Tri
Jurnal Pengabdian Magister Pendidikan IPA Vol 7 No 1 (2024): Januari - Maret
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v7i1.7271

Abstract

Abstract: Upper Respiratory Tract Infection (URTI) or common cold is an acute viral infection that is temporary in nature in the upper respiratory tract, which can also involve the lower respiratory tract. The common cold, which is a combination of typical symptoms, is a common illness that can disrupt activities such as work and school. Children are particularly vulnerable to catching colds due to not having immunity to many viruses, poor personal hygiene, and frequent close contact with other children infected with these viruses. Acupressure is a self-medication technique or treatment involving massage or pressure on the skin surface. Meanwhile, inhalation therapy is a therapy involving the direct delivery of medication to the lungs. The purpose of this community service activity is to increase early knowledge and understanding of self-medication methods for colds using acupressure and aromatherapy inhalation to reduce cold symptoms in students at SDN 02 Terong Tawah. The method of community service activities is using pretest and posttest questionnaires. The results of the community service activity are measured using the One Group Pretest Posttest Design method. Keywords: Cold, URTI, Acupressure, Inhalation Therapy, Self-Medication
Co-Authors ., Ni Luh Putu Widyasari Alfayzah, Faradillah Amalia, Marshanda Fitri Aswal, Dady Syamri Azizah, Hidayatul Baiq Dwiyan Nugrahani Baiq Khaeratinnisa Candra Eka Puspitasari Dea Riski Pebrianti Dhea Syafitri Dwiyanti Dinda Ayu Maulira Fara Mutia Bimantika Fitri, Maulida Khalila Fitriana, Mariama Galuh Suli Pitaloka Gyna Dalila Virginia Hajrin, Wahida Hasbi, Nurmi - Hidayati, Agriana Rosmalina Hudaynu Patya Putri Iga Della Delphia Ika Nur Pratiwi Junaida, Alfini Khalila Fitri, Maulida Lalu M. Rifqi Azami S Laura Navika Yamani Layla Fatihatussir Lestari, Neli Aulia Mahacita Andanalusia Maharani, Della Shinta Manafe, Deary Pretty Genovani Mayada, Silhiyatun Muhammad Dimas Arzy Mukhlisah, Neneng Rachmalia Izzatul Murniati Salam, Mahra Muthiah Ramadhani Nadiya, Aisya Neneng Rachmalia Izzatul Mukhlishah Ni Wayan Puspa Wijaya Suryantarini Nisa Isnaeni Hanifah Nur Azizah Nursalam Nursalam Octavia, Ditha Zanetti Pawanis, Zulfayandi Pratama, Muhammad Imran Ade Putri, Dewi Angelita Qona'ah, Arina Raissa, Talitha Hasna Ramoo, Vimala Ridwan, Sucilawaty Risma Fitriani rizki, alpa alfi Rosyada, Sabila Rosyunita Salam, Mahra Murniati Setyowati, Kirana Ayu SetyowatiSriwidyasari, Ni Luh Ayu Sucilawaty Ridwan Syahrani Febriyanti Tanjaya, Steve Pratama Utari, Weny Syafitri Utari, Widi Gustita Wahida Hajrin Wahida Hajrin Windah Anugrah Subaidah Windah Anugrah Subaidah Yoga Dwi Saputra Yustitia, Nur Tahany Yustitia, Nurtahany ⁠I Gede Eka Surya Buana