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All Journal Chemica: Jurnal Ilmiah Kimia dan Pendidikan Kimia Indonesia Chimica Acta Panrita Abdi - Jurnal Pengabdian pada Masyarakat Al-Kimia Jurnal SOLMA Chemistry Indonesian Journal of Chemical Research Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstorming Abdimas Toddopuli: Jurnal Pengabdian Pada Masyarakat Quimica : Jurnal Kimia Sains dan Terapan Jurnal Ilmiah Wahana Pendidikan Jurnal Abdimas Indonesia : Jurnal Abdimas Indonesia Jurnal Altifani Penelitian dan Pengabdian kepada Masyarakat JURNAL KIMIA SAINTEK DAN PENDIDIKAN Lamahu: Jurnal Pengabdian Masyarakat Terintegrasi Jurnal Atma Inovasia Jurnal TLM Blood Smear Ininnawa: Jurnal Pengabdian Masyarakat Satera: Jurnal Sains dan Teknik Terapan CERATA Abdi Kimia : Jurnal Pengabdian Masyarakat Hayyan Journal Illea
Elfira Jumrah
Universitas Negeri Makassar
Religion Agriculture, Biological Sciences & Forestry Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Other

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(Review Article) Identification of Endophytic Bacteria by 16S rRNA Analysis Elfira Jumrah; Islawati, Islawati; Salnus, Subakir
Jurnal Sains dan Teknik Terapan Vol. 2 No. 2 (2024): Jurnal Sains dan Teknik Terapan
Publisher : Unit Penelitian dan Pengabdian Kepada Masyarakat, AK-Manufaktur Bantaeng

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Abstract

16S rRNA analysis has been used for decades to identify and identify phylogenetic relationships for microorganisms, for instance bacteria. 16S rRNA analysis can identify at the genus and species level. One of the most frequently identified microorganisms using 16S rRNA analysis is endophytic bacteria. Endophytic bacteria have a symbiotic relationship with plants and can synthesis the same compounds as their hosts. The existence of endophytic bacteria benefits their hosts because it can protect plants against insects or pathogens and can help plant growth by producing plant growth regulator compounds, such as IAA, GA3, and cytokinins. In addition, some endophytic bacteria such as Bacillus Burkholderia Enterobacter species, and Staphylococcus sp have antibacterial, antioxidant and anticancer activity. Hence endophytic bacteria need to be identified molecularly. Literature studies show that endophytic bacteria have been successfully isolated from various plants such as Bacillus cereus, Baicillus pumilus, Baicillus siamensis, Burkholderia Enterobacter, and Staphylococcus sp. These endophytic bacteria have antibacterial activity, especially on pathogenic bacteria such as Klebsiella pneumonia, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Salmonella sp.
Analisis Kualitatif Kandungan Formalin dan Boraks pada Daging Ayam Di Beberapa Pasar Makassar Husain, Halimah; jumrah, elfira
Illea : Journal of Health Sciences, Public Health and Medicine Vol.1, No.3 (2025): Oktober 2025
Publisher : Education and Talent Development Center Indonesia (ETDC Indonesia)

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Abstract

This study aims to qualitatively analyze the presence of formalin and borax in chicken meat sold in several traditional markets in Makassar City. The method used is a qualitative test using specific reagents for detecting formalin and borax on five chicken meat samples randomly collected from five different markets. The results show that no borax was detected in any of the tested samples. However, four out of five chicken meat samples were found to contain formalin. These findings indicate that there are still vendors or producers using hazardous substances that are prohibited in food processing. This highlights the need for increased supervision by relevant authorities and public education on the dangers of consuming food products containing harmful chemicals. This study is expected to serve as a reference for policymaking to ensure food safety in Makassar City.
Pemanfaatan Buah Tropis Lokal (Pepaya, Buah Naga, Mangga, dan Nanas) dalam Pembuatan Selai Inovatif Berbasis Pektin Alami Husain, Halimah; Jumrah, Elfira; Ilyas, Nita Magfirah
Chemica: Jurnal Ilmiah Kimia dan Pendidikan Kimia Vol 26, No 2 (2025): CHEMICA
Publisher : Jurusan Kimia FMIPA UNM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35580/chemica.v26i2.81094

Abstract

ABSTRAKPenelitian ini bertujuan untuk mengkaji potensi pemanfaatan buah tropis lokal pepaya (Carica papaya L.), buah naga (Hylocereus polyrhizus), mangga (Mangifera indica L.), dan nanas (Ananas comosus L.) dalam pembuatan selai inovatif berbasis pektin alami. Buah-buahan tersebut dipilih karena ketersediaannya yang melimpah di Indonesia serta kandungan pektinnya yang berperan penting dalam pembentukan tekstur gel pada produk selai. Metode penelitian meliputi tahapan persiapan bahan, penghalusan, pencampuran dengan gula dan asam, pemanasan, serta pengujian pH dan organoleptik. Pektin, gula, dan asam diketahui menjadi faktor utama yang menentukan kualitas fisik dan sensorik selai, seperti kekentalan, kestabilan gel, warna, aroma, dan rasa. Hasil penelitian menunjukkan bahwa seluruh buah tropis yang digunakan menghasilkan selai dengan karakteristik organoleptik yang baik. Selai memiliki tekstur lembut, mudah dioles, warna menarik, aroma khas buah yang segar, serta cita rasa manis-asam yang seimbang. Dari keempat jenis buah, masing-masing memberikan keunikan tersendiri terhadap warna dan aroma akhir produk. Kesimpulannya, pemanfaatan buah tropis lokal berpotensi besar dalam menghasilkan produk selai inovatif berbasis pektin alami yang bernilai ekonomi tinggi, ramah lingkungan, serta dapat meningkatkan nilai tambah hasil pertanian Indonesia.Kata Kunci: Buah tropis lokal, Selai, Pektin alami, OrganoleptikABSTRACTThis study aims to explore the potential utilization of local tropical fruits papaya (Carica papaya L.), dragon fruit (Hylocereus polyrhizus), mango (Mangifera indica L.), and pineapple (Ananas comosus L.) in the production of innovative jams based on natural pectin. These fruits were selected due to their abundance in Indonesia and their natural pectin content, which plays a crucial role in the formation of gel texture in jam products. The research method included several stages: preparation of raw materials, blending, mixing with sugar and acid, heating, and testing for pH and organoleptic properties. Pectin, sugar, and acid were identified as the key components determining the physical and sensory qualities of the jam, such as viscosity, gel stability, color, aroma, and taste. The results showed that all tropical fruits used produced jams with favorable organoleptic characteristics. The jams exhibited a soft and spreadable texture, attractive color, fresh fruity aroma, and a balanced sweet-sour taste. Each fruit contributed its own distinctive color and aroma to the final product. In conclusion, the utilization of local tropical fruits has great potential in producing innovative, natural-pectin-based jams that are economically valuable, environmentally friendly, and capable of enhancing the added value of Indonesia’s agricultural products.Keywords: Local tropical fruits, Jam, Natural pectin, organoleptic 
Pelatihan Pembuatan Sabun Cuci Piring Berbahan Dasar Daun Sirih dan Daun Binahong sebagai Upaya Pemberdayaan Ibu-Ibu PKK Syahdam Karneng; Agustina, Ayu Safitri; Elfira Jumrah; Fitriani Abubakar, Andi Nur; Herdie Idriawien Gusti; Jihad Talib; Sri Sumiati; Nur Ismi; Putri Ramadani Hasra
Jurnal SOLMA Vol. 12 No. 1 (2023)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v12i1.11304

Abstract

Background: Bahan yang digunakan dalam pembuatan sabun cuci piring biasanya menggunakan bahan aktif kimia sintetik yang memiliki dampak negatif bagi lingkungan yaitu dapat mencemari lingkungan. Berdasarkan hal tersebut maka, pengabdian ini dilakukan untuk memanfaatkan daun sirih dan daun binahong sebagai bahan dasar pembuatan sabun cuci piring yang ramah lingkungan dan dapat menciptakan peluang usaha baru yang memberikan pendapatan kepada warga desa. Metode: Kegiatan pengabdian kepada masyarakat ini bermitra dengan kelompok PKK Desa Balong Kec. Ujung Loe Kab. Bulukumba, yang terdiri dari 20 orang anggota. Kegiatan yang diusulkan pada PKM ini adalah sosialisasi kandungan senyawa aktif daun sirih dan daun binahong, pelatihan teknik pembuatan dan proses produksi pengolahan daun sirih dan daun binahong menjadi sabun cuci piring, pelatihan teknik pengemasan dan pelabelan produk, pelatihan manajemen usaha dan pemasaran produk, evaluasi program, serta pendampingan. Hasil: Pengolahan daun sirih dan daun binahong menjadi sabun cuci piring sangat memberikan dampak positif terhadap ibu PKK di Desa Balong, selain mereka dapat membuat sabun cuci piring sendiri, mereka juga dapat memanfaatkan tanaman yang mereka tanam selama ini yang kurang dimanfaatkan. Daun sirih dan daun binahong termasuk tanaman yang mengandung senyawa-senyawa kimia dengan bioaktivitas sebagai antibakteri. Kesimpulan: Dari pelaksanaan kegiatan pengabdian masyarakat yang telah dilakukan dapat disimpulkan bahwa, melalui sosialisasi dan pelatihan ibu-ibu PKK dapat mengetahui manfaat penggunaan daun sirih dan daun binahong dalam pembuatan sabun cuci piring yang ekonomis dan ramah lingkungan.
Pelatihan Produksi Eco-Enzyme Dari Limbah Organik Bagi Masyarakat Sapanang Kecamatan Bungoro Kabupaten Pangkep Pratiwi, Diana Eka; Djangi, Muh. Jasri; Jumrah, Elfira
Ininnawa : Jurnal Pengabdian Masyarakat Vol. 4 No. 1 (2026): Vol. 4 No. 1 (2026): Volume 04 Nomor 01 (Mei 2026)
Publisher : Program Studi Manajemen FEB UNM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26858/svqxt988

Abstract

Household organic waste remains a significant environmental challenge in Indonesia due to limited public awareness and skills in proper waste management. One practical solution is the utilization of organic waste into eco-enzyme, which has both functional and economic value. This Community Service Program (PKM) aimed to improve the knowledge and skills of the community in producing eco-enzyme from organic waste in Sapanang Village, Bungoro District, Pangkep Regency. The implementation methods included socialization, training, hands-on practice, mentoring, and evaluation stages. Evaluation was conducted using pre-test and post-test analyzed through the N-Gain method. The results showed a very high level of participant engagement, with 100% attendance throughout the activities. In addition, there was a significant improvement in participants’ understanding, indicated by an N-Gain score of 0.641 in the moderate category. Participants were able to independently practice eco-enzyme production and understand the indicators of successful fermentation. Continuous mentoring also helped participants overcome technical challenges and maintain consistency in household-level practices. Therefore, this training program proved effective in enhancing community awareness, knowledge, and skills in environmentally friendly organic waste management, while also providing potential opportunities for community-based economic empowerment
Pelatihan Pembuatan Sabun Padat Eco Enzyme untuk Meningkatkan Keterampilan dan Kemandirian Ekonomi Masyarakat Pratiwi, Diana Eka; Djangi, Muh. Jasri; Jumrah, Elfira; Putri, Suriati Eka; Perdana, Rini
Ininnawa : Jurnal Pengabdian Masyarakat Vol. 4 No. 1 (2026): Vol. 4 No. 1 (2026): Volume 04 Nomor 01 (Mei 2026)
Publisher : Program Studi Manajemen FEB UNM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26858/hm9fkn83

Abstract

The problem of household organic waste in Indonesia remains an environmental challenge that requires serious attention. Organic waste such as fruit and vegetable residues is generally not utilized optimally and is often disposed of directly, causing environmental pollution. One environmentally friendly effort to utilize organic waste is through the production of eco enzyme, which can be processed into economically valuable products such as solid soap. This community service activity aimed to improve the knowledge and skills of the community in Sapanang Village, Bungoro District, Pangkep Regency in producing eco enzyme-based solid soap while encouraging community economic independence. The implementation methods included socialization, education, hands-on practical training, mentoring, and evaluation. The results showed that participants demonstrated high enthusiasm during the training and were able to understand the process of making eco enzyme-based solid soap independently. In addition to increasing public awareness regarding the importance of organic waste management, this activity also created opportunities for home-based businesses using environmentally friendly products that have the potential to improve community income. Therefore, the eco enzyme-based solid soap training can serve as a form of community empowerment in supporting sustainable environmental management and improving the community’s economy
Pendekatan Isolasi Fungi Endofit untuk Mendukung Penemuan Obat Berbasis Mikroorganisme elfira jumrah
Illea : Journal of Health Sciences, Public Health and Medicine Vol. 2 No. 2 (2026): Juni
Publisher : Education and Talent Development Center Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/illea.v2i2.5232

Abstract

Endophytic fungi are microorganisms that inhabit healthy plant tissues without causing disease symptoms and represent a promising source of bioactive secondary metabolites for drug discovery. This review evaluates current approaches to endophytic fungal isolation and their implications for microorganism-based drug development. A systematic literature search was conducted across Scopus, Web of Science, PubMed, ScienceDirect, and Google Scholar for publications from 2014–2024. Of 6,583 identified articles, 257 met the inclusion criteria and were analyzed. The review found that surface sterilization using 70% ethanol combined with 2–3% sodium hypochlorite is the most effective and widely adopted protocol. The use of diverse culture media (PDA, MEA, and CDA) enhances isolate diversity, while molecular identification based on ITS-rDNA, supported by LSU, β-tubulin, and TEF1-α markers, provides reliable taxonomic resolution. Furthermore, integrating culture-dependent methods with high-throughput metagenomic sequencing expands access to previously unculturable endophytic fungi. Optimized and standardized isolation protocols, together with omics technologies, are essential for maximizing the potential of endophytic fungi as a sustainable source of novel bioactive compounds and future therapeutic agents.
Pendekatan Multi-Omics untuk Eksplorasi Senyawa Antikanker Fungi Endofit Elfira Jumrah
Illea : Journal of Health Sciences, Public Health and Medicine Vol. 2 No. 2 (2026): Juni
Publisher : Education and Talent Development Center Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/illea.v2i2.5268

Abstract

Cancer remains one of the leading causes of mortality worldwide, while conventional therapies are often limited by drug resistance, toxicity, and poor selectivity toward cancer cells. Endophytic fungi represent a promising source of anticancer compounds due to their ability to produce a wide variety of bioactive secondary metabolites. However, much of their biosynthetic potential remains unexplored because many biosynthetic gene clusters (BGCs) are cryptic or remain silent under standard laboratory conditions. This review aims to evaluate the roles of genomics, transcriptomics, proteomics, metabolomics, and epigenomics in the discovery of anticancer compounds from endophytic fungi and to highlight the potential of multi-omics integration for accelerating natural product discovery. The review was conducted using a systematic literature review approach based on the PRISMA 2020 guidelines.. The findings demonstrate that genomics facilitates BGC identification, transcriptomics reveals gene expression dynamics, proteomics identifies key enzymes and molecular targets, metabolomics enables metabolite characterization, and epigenomics contributes to the activation of cryptic gene clusters. The integration of these omics platforms provides a more comprehensive understanding of the relationship between genotype and metabolic phenotype, thereby enhancing the efficiency of discovering novel anticancer compounds. Nevertheless, challenges related to data integration, functional validation, and clinical translation remain significant. Therefore, multi-omics approaches combined with artificial intelligence and machine learning are expected to play a crucial role in advancing endophytic fungi as a valuable source of future anticancer drug candidates.
Bioactive Potential of Endophytic Fungi from the Genus Aspergillus: A Comprehensive Review of Secondary Metabolites and Their Biological Activities elfira jumrah
Hayyan Journal Vol. 2 No. 3 (2025): October
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i3.4222

Abstract

This review provides a comprehensive synthesis of current knowledge on the bioactive potential of endophytic fungi belonging to the genus Aspergillus, emphasizing their secondary metabolites and associated biological activities. A systematic literature search was conducted across major scientific databases, including Scopus, Web of Science, PubMed, ScienceDirect, and Google Scholar, covering publications from January 2020 to October 2025. Studies were selected based on inclusion criteria focusing on the isolation, metabolite characterization, and bioactivity evaluation of endophytic Aspergillus species. Relevant data on fungal species, host plants, metabolite classes, and biological functions were extracted, organized, and analyzed qualitatively using a thematic and comparative approach. The analysis revealed that Aspergillus species are prolific producers of diverse secondary metabolites such as alkaloids, polyketides, terpenoids, xanthones, and peptides, exhibiting a broad range of biological activities including antimicrobial, antioxidant, anticancer, anti-inflammatory, antifungal, and antiparasitic effects. Key compounds such as gliotoxin, terrein, and vitexin demonstrate strong pharmacological properties and highlight the genus’s biotechnological significance. Overall, endophytic Aspergillus species represent an underexploited reservoir of natural bioactive compounds with high pharmaceutical and industrial relevance. Future research integrating genomics, metabolomics, and bioengineering is essential to unlock their full biosynthetic potential and advance sustainable drug discovery.
Ethnopharmacology of Indigofera tinctoria (Linn.): Bridging Traditional Knowledge and Evidence-Based Medicine Elfira Jumrah
Hayyan Journal Vol. 3 No. 1 (2026): February
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v3i1.5057

Abstract

Indigofera tinctoria (Linn.), commonly known as true indigo, is a medicinal plant traditionally used in various ethnomedical systems, including Ayurveda, Traditional Chinese Medicine (TCM), and African traditional medicine. Beyond its historical role as a natural dye source, the plant has attracted increasing scientific interest due to its diverse pharmacological properties and bioactive constituents. This review aimed to systematically evaluate the ethnopharmacological uses, phytochemical composition, and pharmacological activities of I. tinctoria, while highlighting its potential for evidence-based therapeutic applications. A narrative review with a systematic literature search approach was conducted using electronic databases, including Scopus, PubMed, Web of Science, Google Scholar, and ScienceDirect. Relevant studies published between 2020 and 2026 were identified using keywords related to Indigofera tinctoria, ethnopharmacology, phytochemistry, and pharmacological activity. Study selection followed PRISMA guidelines, and a total of 45 eligible studies were included in the qualitative synthesis. The findings demonstrated that I. tinctoria has been traditionally utilized for the treatment of inflammatory disorders, skin diseases, infections, liver dysfunction, fever, and metabolic abnormalities. Phytochemical analyses revealed the presence of flavonoids, alkaloids, tannins, saponins, terpenoids, phenolic compounds, indigo, and indirubin, which contribute to its biological activities. Experimental studies reported significant anti-inflammatory, antioxidant, antimicrobial, hepatoprotective, antidiabetic, and immunomodulatory effects. Among the identified compounds, indirubin showed notable pharmacological potential due to its anti-inflammatory and antiproliferative properties. However, the current evidence remains predominantly based on in vitro and animal studies, while clinical validation in humans is still limited. In conclusion, Indigofera tinctoria possesses promising ethnopharmacological and therapeutic potential supported by growing scientific evidence. Nevertheless, further studies focusing on standardized phytochemical characterization, mechanistic investigations, toxicological assessments, and randomized clinical trials are necessary to facilitate its translation into evidence-based phytotherapeutic applications.
Co-Authors Abubakar, Andi Nur Fitriani Adriyanti, Refani Ainun Musfira Alam, Muhammad Nur Alda, Nurfadhilah Amalia Luqman, Alya Amran, Aimar Ananda Andi Nur Fitriani Abubakar Andi Nur Fitriani Abubakar Astuti, Kartika Novi Ayu Safitri Agustina Azis, Suhartini Aziz, Rahmawati Dewiyanti Fadly Diana Eka Pratiwi Djangi, Muh. Jasri Dwi Gladinda, Virginia Elsye Dea, Secilia Fandi Ahmad Fandi Ahmad Fitri Yulianti Fitriani Abubakar, Andi Nur Gusti, Herdi Idriawien Gusti, Herdie Idriawien Hastuti Agussalim Herdie Idriawien Gusti Herdie Idriawien Gusti Ilyas, Nita Magfirah Islawati Karneng, Syahdam Khairunnisa, Rifqiani Marsandah Mega Fatimah Rosana Muhammad Isbar Pratama Muhammad Yunus Munawwarah Munawwarah Munawwarah Mutmainna Nur Afni Nur Indah Sari Nur Ismi NUR ISMI Nur Ismi, Ismi Nurwijayanti Purnama, Andry Priyadharmadi Putri Ramadani Asra Putri Ramadani Hasra Putri Ramadani Hasra R. Rusli Refani Adriyanti Rini Perdana Rosmaniar Saadatul Husna Salnus, Subakir Siti Fatimah Sri Hardiyanti, Sri Sri Sumiati Sri Sumiati Sri Sumiati Sudding, Sudding Suhartini Azis Sukaria, Muhammad Ikhsan Suriati Eka Putri Syahdam Karneng Syahdam Karneng Talib, Jihad Vika Puji Cahyani Yunus, Muh Zachrina, Dwiny Zulkarnain, A. Mutiara