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All Journal Chemica: Jurnal Ilmiah Kimia dan Pendidikan Kimia Indonesia Chimica Acta Panrita Abdi - Jurnal Pengabdian pada Masyarakat Al-Kimia Jurnal SOLMA Chemistry Indonesian Journal of Chemical Research Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstorming Quimica : Jurnal Kimia Sains dan Terapan Jurnal Ilmiah Wahana Pendidikan Jurnal Abdimas Indonesia : Jurnal Abdimas Indonesia Jurnal Altifani Penelitian dan Pengabdian kepada Masyarakat JURNAL KIMIA SAINTEK DAN PENDIDIKAN Lamahu: Jurnal Pengabdian Masyarakat Terintegrasi Jurnal Atma Inovasia Jurnal TLM Blood Smear Ininnawa: Jurnal Pengabdian Masyarakat Satera: Jurnal Sains dan Teknik Terapan CERATA Journal of Educational Technology and Learning Creativity Abdi Kimia : Jurnal Pengabdian Masyarakat Hayyan Journal Illea
Elfira Jumrah
Universitas Negeri Makassar
Religion Agriculture, Biological Sciences & Forestry Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Pelatihan Produksi Eco-Enzyme Dari Limbah Organik Bagi Masyarakat Sapanang Kecamatan Bungoro Kabupaten Pangkep Pratiwi, Diana Eka; Djangi, Muh. Jasri; Jumrah, Elfira
Ininnawa : Jurnal Pengabdian Masyarakat Vol. 4 No. 1 (2026): Vol. 4 No. 1 (2026): Volume 04 Nomor 01 (Mei 2026)
Publisher : Program Studi Manajemen FEB UNM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26858/svqxt988

Abstract

Household organic waste remains a significant environmental challenge in Indonesia due to limited public awareness and skills in proper waste management. One practical solution is the utilization of organic waste into eco-enzyme, which has both functional and economic value. This Community Service Program (PKM) aimed to improve the knowledge and skills of the community in producing eco-enzyme from organic waste in Sapanang Village, Bungoro District, Pangkep Regency. The implementation methods included socialization, training, hands-on practice, mentoring, and evaluation stages. Evaluation was conducted using pre-test and post-test analyzed through the N-Gain method. The results showed a very high level of participant engagement, with 100% attendance throughout the activities. In addition, there was a significant improvement in participants’ understanding, indicated by an N-Gain score of 0.641 in the moderate category. Participants were able to independently practice eco-enzyme production and understand the indicators of successful fermentation. Continuous mentoring also helped participants overcome technical challenges and maintain consistency in household-level practices. Therefore, this training program proved effective in enhancing community awareness, knowledge, and skills in environmentally friendly organic waste management, while also providing potential opportunities for community-based economic empowerment
Pelatihan Pembuatan Sabun Padat Eco Enzyme untuk Meningkatkan Keterampilan dan Kemandirian Ekonomi Masyarakat Pratiwi, Diana Eka; Djangi, Muh. Jasri; Jumrah, Elfira; Putri, Suriati Eka; Perdana, Rini
Ininnawa : Jurnal Pengabdian Masyarakat Vol. 4 No. 1 (2026): Vol. 4 No. 1 (2026): Volume 04 Nomor 01 (Mei 2026)
Publisher : Program Studi Manajemen FEB UNM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26858/hm9fkn83

Abstract

The problem of household organic waste in Indonesia remains an environmental challenge that requires serious attention. Organic waste such as fruit and vegetable residues is generally not utilized optimally and is often disposed of directly, causing environmental pollution. One environmentally friendly effort to utilize organic waste is through the production of eco enzyme, which can be processed into economically valuable products such as solid soap. This community service activity aimed to improve the knowledge and skills of the community in Sapanang Village, Bungoro District, Pangkep Regency in producing eco enzyme-based solid soap while encouraging community economic independence. The implementation methods included socialization, education, hands-on practical training, mentoring, and evaluation. The results showed that participants demonstrated high enthusiasm during the training and were able to understand the process of making eco enzyme-based solid soap independently. In addition to increasing public awareness regarding the importance of organic waste management, this activity also created opportunities for home-based businesses using environmentally friendly products that have the potential to improve community income. Therefore, the eco enzyme-based solid soap training can serve as a form of community empowerment in supporting sustainable environmental management and improving the community’s economy
Pendekatan Isolasi Fungi Endofit untuk Mendukung Penemuan Obat Berbasis Mikroorganisme elfira jumrah
Illea : Journal of Health Sciences, Public Health and Medicine Vol. 2 No. 2 (2026): Juni
Publisher : Education and Talent Development Center Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/illea.v2i2.5232

Abstract

Endophytic fungi are microorganisms that inhabit healthy plant tissues without causing disease symptoms and represent a promising source of bioactive secondary metabolites for drug discovery. This review evaluates current approaches to endophytic fungal isolation and their implications for microorganism-based drug development. A systematic literature search was conducted across Scopus, Web of Science, PubMed, ScienceDirect, and Google Scholar for publications from 2014–2024. Of 6,583 identified articles, 257 met the inclusion criteria and were analyzed. The review found that surface sterilization using 70% ethanol combined with 2–3% sodium hypochlorite is the most effective and widely adopted protocol. The use of diverse culture media (PDA, MEA, and CDA) enhances isolate diversity, while molecular identification based on ITS-rDNA, supported by LSU, β-tubulin, and TEF1-α markers, provides reliable taxonomic resolution. Furthermore, integrating culture-dependent methods with high-throughput metagenomic sequencing expands access to previously unculturable endophytic fungi. Optimized and standardized isolation protocols, together with omics technologies, are essential for maximizing the potential of endophytic fungi as a sustainable source of novel bioactive compounds and future therapeutic agents.
Pendekatan Multi-Omics untuk Eksplorasi Senyawa Antikanker Fungi Endofit Elfira Jumrah
Illea : Journal of Health Sciences, Public Health and Medicine Vol. 2 No. 2 (2026): Juni
Publisher : Education and Talent Development Center Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/illea.v2i2.5268

Abstract

Cancer remains one of the leading causes of mortality worldwide, while conventional therapies are often limited by drug resistance, toxicity, and poor selectivity toward cancer cells. Endophytic fungi represent a promising source of anticancer compounds due to their ability to produce a wide variety of bioactive secondary metabolites. However, much of their biosynthetic potential remains unexplored because many biosynthetic gene clusters (BGCs) are cryptic or remain silent under standard laboratory conditions. This review aims to evaluate the roles of genomics, transcriptomics, proteomics, metabolomics, and epigenomics in the discovery of anticancer compounds from endophytic fungi and to highlight the potential of multi-omics integration for accelerating natural product discovery. The review was conducted using a systematic literature review approach based on the PRISMA 2020 guidelines.. The findings demonstrate that genomics facilitates BGC identification, transcriptomics reveals gene expression dynamics, proteomics identifies key enzymes and molecular targets, metabolomics enables metabolite characterization, and epigenomics contributes to the activation of cryptic gene clusters. The integration of these omics platforms provides a more comprehensive understanding of the relationship between genotype and metabolic phenotype, thereby enhancing the efficiency of discovering novel anticancer compounds. Nevertheless, challenges related to data integration, functional validation, and clinical translation remain significant. Therefore, multi-omics approaches combined with artificial intelligence and machine learning are expected to play a crucial role in advancing endophytic fungi as a valuable source of future anticancer drug candidates.
Bioactive Potential of Endophytic Fungi from the Genus Aspergillus: A Comprehensive Review of Secondary Metabolites and Their Biological Activities elfira jumrah
Hayyan Journal Vol. 2 No. 3 (2025): October
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i3.4222

Abstract

This review provides a comprehensive synthesis of current knowledge on the bioactive potential of endophytic fungi belonging to the genus Aspergillus, emphasizing their secondary metabolites and associated biological activities. A systematic literature search was conducted across major scientific databases, including Scopus, Web of Science, PubMed, ScienceDirect, and Google Scholar, covering publications from January 2020 to October 2025. Studies were selected based on inclusion criteria focusing on the isolation, metabolite characterization, and bioactivity evaluation of endophytic Aspergillus species. Relevant data on fungal species, host plants, metabolite classes, and biological functions were extracted, organized, and analyzed qualitatively using a thematic and comparative approach. The analysis revealed that Aspergillus species are prolific producers of diverse secondary metabolites such as alkaloids, polyketides, terpenoids, xanthones, and peptides, exhibiting a broad range of biological activities including antimicrobial, antioxidant, anticancer, anti-inflammatory, antifungal, and antiparasitic effects. Key compounds such as gliotoxin, terrein, and vitexin demonstrate strong pharmacological properties and highlight the genus’s biotechnological significance. Overall, endophytic Aspergillus species represent an underexploited reservoir of natural bioactive compounds with high pharmaceutical and industrial relevance. Future research integrating genomics, metabolomics, and bioengineering is essential to unlock their full biosynthetic potential and advance sustainable drug discovery.
Ethnopharmacology of Indigofera tinctoria (Linn.): Bridging Traditional Knowledge and Evidence-Based Medicine Elfira Jumrah
Hayyan Journal Vol. 3 No. 1 (2026): February
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v3i1.5057

Abstract

Indigofera tinctoria (Linn.), commonly known as true indigo, is a medicinal plant traditionally used in various ethnomedical systems, including Ayurveda, Traditional Chinese Medicine (TCM), and African traditional medicine. Beyond its historical role as a natural dye source, the plant has attracted increasing scientific interest due to its diverse pharmacological properties and bioactive constituents. This review aimed to systematically evaluate the ethnopharmacological uses, phytochemical composition, and pharmacological activities of I. tinctoria, while highlighting its potential for evidence-based therapeutic applications. A narrative review with a systematic literature search approach was conducted using electronic databases, including Scopus, PubMed, Web of Science, Google Scholar, and ScienceDirect. Relevant studies published between 2020 and 2026 were identified using keywords related to Indigofera tinctoria, ethnopharmacology, phytochemistry, and pharmacological activity. Study selection followed PRISMA guidelines, and a total of 45 eligible studies were included in the qualitative synthesis. The findings demonstrated that I. tinctoria has been traditionally utilized for the treatment of inflammatory disorders, skin diseases, infections, liver dysfunction, fever, and metabolic abnormalities. Phytochemical analyses revealed the presence of flavonoids, alkaloids, tannins, saponins, terpenoids, phenolic compounds, indigo, and indirubin, which contribute to its biological activities. Experimental studies reported significant anti-inflammatory, antioxidant, antimicrobial, hepatoprotective, antidiabetic, and immunomodulatory effects. Among the identified compounds, indirubin showed notable pharmacological potential due to its anti-inflammatory and antiproliferative properties. However, the current evidence remains predominantly based on in vitro and animal studies, while clinical validation in humans is still limited. In conclusion, Indigofera tinctoria possesses promising ethnopharmacological and therapeutic potential supported by growing scientific evidence. Nevertheless, further studies focusing on standardized phytochemical characterization, mechanistic investigations, toxicological assessments, and randomized clinical trials are necessary to facilitate its translation into evidence-based phytotherapeutic applications.
Effect of Liquid and Solid Salting Methods on the Organoleptic Characteristics of Traditional Salted Eggs Elfira Jumrah
Hayyan Journal Vol. 3 No. 2 (2026): June
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v3i2.5156

Abstract

This study aimed to evaluate the effect of solid and liquid salting methods on the organoleptic characteristics of traditional salted eggs. The research employed an experimental method using different salt concentrations in both salting media. The solid salting method utilized mixtures of salt and ash at ratios of 1:3, 1:4, and 1:5, while the liquid salting method used salt-water ratios of 1:0.5, 1:0.4, and 1:0.3 supplemented with garlic and chili peppers as natural flavoring agents. Duck eggs were cured for 7 days at room temperature and subsequently boiled before organoleptic evaluation. Sensory analysis was conducted based on color, aroma, taste, texture, and overall acceptance. The results showed that both salting methods significantly affected the sensory quality of salted eggs. In the solid salting treatment, the 1:3 salt-to-ash ratio produced the best characteristics, including bright orange yolk color, firm texture, balanced salty taste, and desirable aroma. Meanwhile, in the liquid salting treatment, the 1:0.5 salt-to-water ratio was the most preferred by panelists due to its attractive orange yolk color, balanced saltiness, soft texture, and pleasant spicy aroma derived from garlic and chili peppers. Higher salt concentrations promoted better osmotic dehydration, protein denaturation, and yolk texture formation, resulting in improved organoleptic quality. In conclusion, both solid and liquid salting methods effectively produced salted eggs with acceptable sensory properties; however, salt concentration and salting media played important roles in determining product quality. Optimization of salting conditions is therefore essential for producing traditional salted eggs with superior organoleptic characteristics and higher consumer acceptance.
Pemberdayaan Ibu Rumah Tangga Melalui Pelatihan Pembuatan Eco-enzyme berbasis Limbah Rumah Tangga Elfira Jumrah; Rini Perdana; Suhartini Azis; Refani Adriyanti; Aimar Ananda Amran
Jurnal Altifani Penelitian dan Pengabdian kepada Masyarakat Vol. 5 No. 6 (2025): November 2025 - Jurnal Altifani Penelitian dan Pengabdian kepada Masyarakat
Publisher : Indonesian Scientific Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59395/altifani.v5i6.895

Abstract

Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memberdayakan ibu rumah tangga melalui pelatihan pembuatan Eco-enzyme berbasis limbah rumah tangga. Permasalahan pengelolaan sampah organik yang sering menimbulkan pencemaran lingkungan menjadi latar belakang dilaksanakannya program ini. Metode kegiatan meliputi penyampaian materi terkait dampak limbah organik, potensi Eco-enzyme sebagai solusi ramah lingkungan, serta praktik langsung pembuatan Eco-enzyme dengan memanfaatkan limbah dapur, gula merah, dan air. Pelatihan dilaksanakan secara interaktif sehingga peserta tidak hanya memahami teori, tetapi juga mampu mempraktikkan proses fermentasi secara mandiri. Hasil kegiatan menunjukkan bahwa peserta antusias, aktif berdiskusi, serta mampu mengikuti setiap tahap dengan baik. Kegiatan ini berhasil meningkatkan pengetahuan dan keterampilan ibu rumah tangga dalam mengolah sampah organik menjadi produk bernilai guna, sekaligus mendorong terciptanya perilaku ramah lingkungan dan peluang pemanfaatan ekonomi lokal.
Technical Computational Approach for Drug Discovery: in silico Analysis of Non-Edible Parts of Durio oxleyanus from Sabah as Enzyme Inhibitors in Diabetes Management Qomariah Hasanah; Monica Suleiman; Ayu Indayanti Ismail; Elfira Jumrah; Nur Hasanah; Syahriel bin Abdullah
Journal of Educational Technology and Learning Creativity Vol. 4 No. 1 (2026): June
Publisher : Cahaya Ilmu Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37251/jetlc.v4i1.3179

Abstract

Purpose of the study: One strategy for controlling blood glucose levels is to inhibit carbohydrate digestion enzymes, namely α-glucosidase and α-amylase. This study uses a technical computational approach to explore the bioactive potential of the inedible part (husk) of Durio oxleyanus from Sabah as an inhibitor of both enzymes. Methodology: Hydroalcoholic extracts were analyzed using LC-MS, which identified phenolic and flavonoid compounds including catechin, rutin, quercetin, malvidin-3-O-glucoside, and lucidenic acid D1. Molecular docking simulations were performed against α-glucosidase (PDB ID: 2QMJ) and α-amylase (PDB ID: 1B2Y) using PyRx integrated with AutoDock and AutoDock Vina. Main Findings: The results showed that several compounds had high binding affinity (ΔG ≤ -7.0 kcal/mol) and interacted stably with polar, aromatic, and hydrophobic residues in the enzyme's active site. Lucidenic acid D1, rutin, catechin, and quercetin-3-O-glucosidase stood out as the main candidates with the lowest binding energy and multipoint interactions that support the formation of stable complexes. Novelty/Originality of this study: This study has demonstrated significant innovation by revealing the potential of the inedible parts of Durio oxleyanus as a source of candidate antidiabetic drugs through a computational approach. The integration of LC-MS profiling and molecular docking enables the efficient identification of bioactive compounds while accelerating the drug discovery process without relying entirely on experimental methods. This research lies in its contribution to the concept of sustainable bioprospecting, the exploration of under-researched local biodiversity, and the multi-target validation of key diabetes enzymes.
Co-Authors Abubakar, Andi Nur Fitriani Aimar Ananda Amran Ainun Musfira Alda, Nurfadhilah Amalia Luqman, Alya Andi Nur Fitriani Abubakar Andi Nur Fitriani Abubakar Astuti, Kartika Novi Ayu Indayanti Ismail Ayu Safitri Agustina Aziz, Rahmawati Dewiyanti Fadly Diana Eka Pratiwi Djangi, Muh. Jasri Dwi Gladinda, Virginia Fandi Ahmad Fandi Ahmad Fitri Yulianti Fitriani Abubakar, Andi Nur Gusti, Herdi Idriawien Gusti, Herdie Idriawien Herdie Idriawien Gusti Herdie Idriawien Gusti Ilyas, Nita Magfirah Islawati Karneng, Syahdam Khairunnisa, Rifqiani Marsandah Mega Fatimah Rosana Monica Suleiman Muhammad Isbar Pratama Muhammad Yunus Munawwarah Munawwarah Munawwarah Mutmainna Nur Hasanah Nur Indah Sari Nur Ismi NUR ISMI Nur Ismi, Ismi Nurwijayanti Purnama, Andry Priyadharmadi Putri Ramadani Asra Putri Ramadani Hasra Putri Ramadani Hasra Qomariah Hasanah R. Rusli Refani Adriyanti Rini Perdana Rosmaniar Saadatul Husna Salnus, Subakir Siti Fatimah Sri Hardiyanti, Sri Sri Sumiati Sri Sumiati Sri Sumiati Sudding, Sudding Suhartini Azis Sukaria, Muhammad Ikhsan Suriati Eka Putri Syahdam Karneng Syahdam Karneng Syahriel bin Abdullah Talib, Jihad Vika Puji Cahyani Yunus, Muh Zachrina, Dwiny Zulkarnain, A. Mutiara