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Observasi Kesembuhan Distant Skin Flap yang dirawat dengan Dry Dressing dan Moist Dressing Erwin, Erwin; Syafruddin, Syafruddin; Karmil, Fadrial; Sugito, Sugito; Daud, Razali; Roslizawaty, Roslizawaty; Zainuddin, Zainuddin; Luksmana, Roby
Acta VETERINARIA Indonesiana Vol. 8 No. 2 (2020): Juli 2020
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (848.855 KB)

Abstract

Distant flap adalah teknik bedah untuk merekonstruksi luka yang jauh dari sumber flaps berasal. Penelitian ini bertujuan mengetahui perbedaan kesembuhan luka distant skin flap dengan perawatan dry dressing dan moist dressing secara subjektif dan objektif. Penelitian ini menggunakan 6 ekor kucing lokal jantan berumur 1-2 tahun dengan berat badan 2-3 kg, dibagi menjadi 2 kelompok perlakuan. Semua kucing dibuat luka dengan ukuran 2x2 cm pada kulit metacarpus, luka ditangani dengan teknik distant skin flap yang berasal dari lateral thoraks sebagai sumber flaps. Distant skin flap dirawat dengan dry dressing menggunakan kasa steril (K-I) dan moist dressing menggunakan sofratulle® (K-II). Pengamatan subjektif kesembuhan distant skin flap pada hari ke-3, 6, 9 dan 12 pasca bedah, sedangkan uji pendarahan dan pengamatan objektif pada hari ke-18 pasca bedah. Data kuantitatif pengamatan subjektif dan objektif dianalisis menggunakan analisis varian multivariate dan post hoc test Duncan dengan bantuan perangkat lunak SPSS versi 25. Hasil pengamatan subjektif menunjukkan kesembuhan luka distant skin flap yang dirawat dengan moist dressing lebih baik dari pada dry dressing. Hari ke-12 warna kulit flaps kembali sama dengan kulit sekitar, respon nyeri berkurang, dan pertumbuhan rambut lebih cepat. Pengamatan objektif menunjukkan waktu absorbsi NaCl 0,9% dan efek obat lebih cepat pada kelompok moist dressing. Kesembuhan distant skin flap yang dirawat dengan moist dressing lebih cepat dibandingkan dengan dry dressing.
Potential of ant nest extract (Hydnophytum formicarum) for protection of testicular morphometry, epididymal functions, and sperm quality in male rats with alloxan-induced diabetes Roslizawaty, Roslizawaty; Abrar, Mahdi; Khairan, Khairan; Gholib, Gholib; Siregar, Tongku N.; Syafruddin, Syafruddin; Sutriana, Amalia; Azzahra, Putri; Aini, Hanipah
Narra J Vol. 4 No. 3 (2024): December 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i3.922

Abstract

Medicinal herbs, such as the ant nest plant (Hydnophytum formicarum), are promising for the management of diabetes mellitus-associated infertility. The aim of this study was to evaluate the biological activity of the ant nest plant and its capacity to mitigate the adverse effects of alloxan-induced diabetes on testicular morphology, epididymal function, and sperm quality in male rats. The tuber of the ant nest plant was extracted using methanol and then subjected to phytochemical screenings. For the experiment, 20 male white rats (Rattus norvegicus), aged 3–4 months and weighing 150–200 g, were equally divided into four groups. The ant nest extract was administered orally using oral gavage over 14 days. The testes, epididymis, and sperm were collected for weighing, morphometric measurements, and quality evaluation. Qualitative testing of phytochemical compounds indicated the presence of flavonoids, tannins, steroids, terpenoids, and phenolic compounds in the plants. The results revealed the protective effects of ant nest extract against the adverse fertility effects induced by alloxan and a high-fat diet, as observed in testicular weight (p=0.045), epididymal weight (p=0.041), and sperm quality (p>0.05).
Diagnosis of ehrlichiosis and anaplasmosis in fila brasileiro dog Usrina, Nora; Zulkifli, Baidillah; Hidayat, Farah Amalia; Daniel, Daniel; Nurliana, Nurliana; Roslizawaty, Roslizawaty; Athaillah, Farida; Yusriani, Yenni
The International Journal of Tropical Veterinary and Biomedical Research Vol 10, No 1 (2025): Vol 10 (1) May 2025
Publisher : The Faculty of Veterinary Medicine of Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/ijtvbr.v10i1.45754

Abstract

Background and Aim: Canine ehrlichiosis and anaplasmosis are significant tick-borne diseases with global distribution and high clinical relevance in veterinary medicine. This case report presents a ten-year-old male Fila Brasileiro dog exhibiting clinical signs of anorexia and lethargy for three consecutive days.Materials and Methods: Physical examination revealed fever (40.3 C), pale mucous membranes, and a body condition score of 3/5. A complete blood count (CBC) showed leukocytosis, neutrophilia, eosinophilia, microcytic anemia, and thrombocytopenia. Further confirmation using a SNAP 4Dx rapid test detected antibodies against Ehrlichia spp. and Anaplasma spp., leading to a definitive diagnosis of ehrlichiosis and anaplasmosis. Treatment involved fluid therapy using intravenous 0.9% sodium chloride and doxycycline at a dose of 250 mg per day for 21 days.Results : The hematological findings align with typical abnormalities observed in dogs with these infections, including reduced erythrocyte and platelet counts, which are associated with immune-mediated destruction and bone marrow suppression. These pathogens also alter neutrophil function to evade the host immune response, contributing to prolonged inflammation and disease progression. The hematological profile presented here demonstrates a rare combination of microcytic anemia and eosinophilia, which may suggest an atypical host immune response not commonly described in previous literature.Conclusion: This case highlights the importance of early diagnosis through hematological and serological examinations and emphasizes the need for routine tick prevention to reduce the risk of tick-borne diseases in dogs.
HISTOPATHOLOGICAL OVERVIEW OF NEW ZEALAND WHITE PSEUDO-PREGNANT RABBIT UTERUS AFTER OVARY TRANSPLANTATION WITH VARYING DURATION OF OVARIES INSIDE THE UTERUS Nazaruddin, Nazaruddin; Fadillah, Nurul Aini; Melia, Juli; Thasmi, Cut Nila; Roslizawaty, Roslizawaty; Sayuti, Arman; Daud, Razali; Adam, Mulyadi; Syafruddin, Syafruddin
Jurnal Kedokteran Hewan Vol 17, No 4 (2023): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v17i4.34694

Abstract

This study aims to understand the histopathological changes in the pseudo-pregnant rabbit uterus concerning the duration of ovaries inside the uterus during ovarian transplantation. The study used nine New Zealand White (NZW) pseudo-pregnant female rabbits aged 3-5 years, weighed 1.5-2.9 kg. After a 30-day adaptation period, all rabbits were divided into three treatment groups: K1 (n=3) underwent ovarian transplantation for 3 days, K2 (n=3) for 5 days, and K3 (n=3) for 7 days. Pseudo-pregnant was induced using PMSG and hCG. The rabbits were intramuscularly injected with 100 IU of PMSG, followed by intravenous injection of 75 IU of hCG three days later. Ovary transplantation was performed on the 8th day (day 0 being the day of hCG injection). Uterus was collected after the transplantation procedure according to the respective treatment groups. The results showed that in K1, K2 and K3, there was hyperemia in the endometrial epithelium and infiltration of inflammatory cells. Hyperemia and necrosis were more severe in K1 compared to K2 and K3. In K3, the histopathological appearance of the endometrium tended to be normal, with less damage. In conclusion, the histopathological findings of hyperemia and necrosis in the uterus undergoing ovarian transplantation lasted for 3 days compared to 5 and 7 days.
THE EFFECT OF SUPEROVULATION INDUCTION USING FSH ON INCREASING FSH AND LH CONCENTRATIONS IN NEW ZEALAND WHITE RABBITS Wahyuni, Sri; Fathurrahman, Fadhil; Adam, Mulyadi; Syafruddin, Syafruddin; Roslizawaty, Roslizawaty; Hasan, Muhammad; Melia, Juli; Dasrul, Dasrul; Isa, Muhammad; Rosmaidar, Rosmaidar
Jurnal Kedokteran Hewan Vol 18, No 1 (2024): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i1.37513

Abstract

This study aimed to determine the concentrations of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) in New Zealand White (NZW) rabbits after superovulation induction using FSH. Six female NZW rabbits and one male NZW rabbit were used in this study. Criteria for female NZW rabbits used include having previously given birth, not being pregnant, and having a body weight of 2-3 kg. The rabbits were divided into two treatment groups; the first group was injected with physiological NaCl (NZW1, n= 3), while the second group was injected with FSH (NZW2, n= 3). Injections of physiological NaCl or FSH were administered five times at 12-hour intervals and first injection was given at 20:00 p.m. In NZW1, each injection was given physiological NaCl with volumes of 0.2:0.2+0.2;0.4+0.4 mL, respectively whereas in NZW2, each injection was given FSH with doses of 4:4+4:8+8 mg, respectively. Twelve hours after the last FSH injection, NZW2 rabbits were injected with 100 IU hCG and mated with male rabbit, while NZW1 rabbits were mated without hCG administration. On days 1, 3, and 5 after mating, blood samples were collected for FSH and LH hormone examination using the Enzyme-Linked Immunosorbent Assay (ELISA) method. The FSH concentrations on days 1, 3, and 5 between NZW1 vs NZW2 were 34.781.46 vs 39.753.18; 41.434.90 vs 41.425.14; and 44.471.51 vs 30.130.19 mIU/mL, respectively (P0.05). The LH concentrations on days 1, 3, and 5 between NZW1 vs NZW2 were 33.784.01 vs 40.1812.36; 29.342.24 vs 31.3110.13; and 42.0911.38 vs 30.578.87 mIU/mL, respectively (P0.05). It is concluded that FSH administration does not affect the concentrations of FSH and LH in NZW rabbits. The FSH concentration five days after mating tends to fluctuate, while the LH concentration tends to decrease as the days increased.
EFFECT OF SALINITY CHANGES ON METHIONINE CONTENT IN TIGER GROUPER JUVENILE (Epinephelus fuscoguttatus) Abbas, Muhammadar Abdullah; Abidin, Muchlisin Zainal; Putra, Dedi Fazriansyah; Firdus, Firdus; Batubara, Agung Setia; Sail, Asmawati Muhammad; Syafruddin, Syafruddin; Roslizawaty, Roslizawaty; Sutriana, Amalia; Aliza, Dwinna
Jurnal Kedokteran Hewan Vol 12, No 4 (2018): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v12i4.12363

Abstract

This study was conducted to determine the effect of water salinity changes on methionine content in tiger grouper juvenile (Epinephelus fuscoguttatus). A total of 2,560 tiger grouper juveniles were used and divided into five groups consist of 1 control group (without exposed to salinity changes) and 4 treatment groups. The salinity was changed every 2, 3, 4, and 6 hours in treatment A, B, C, and D, respectively. Salinity levels were changed during 24 hours by lowering salinity level from 32 psu to 22 psu. Twenty five of fish were collected from each treatment for methionine content analysis. Data were analysed using one way analysis of variance (ANOVA). The results showed that there was a decrease in methionine content in all treatments. A significant decrease (P0.05) of methionine content in treatment A, B, and C were observed after 20 hours (1.15%), 18 hours (1.27%), and 16 hours (1.24%), respectively. While at 0 hours (control), the methionine content was 2.02%. Methionine level in treatment D was not significantly different (P0.05) compared to control group. As conclusion, rearing the tiger grouper juvenile with salinity fluctuations every 6 hours did not lead to methionine deficiency.
The Use of Sour Soup (Annona murricata) Seed Powder as Acaricide on Cow and Goat Fahrimal, Yudha; Daud, Razali; Chandra, Adi; Iqbal, Syauki; Roslizawaty, Roslizawaty
Jurnal Kedokteran Hewan Vol 4, No 1 (2010): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v4i1.9797

Abstract

This research was aimed to study curative effect of sour soup seed powder on cattle invested with ticks and goat infected with scabies. This study was using 12 cattle invested with ticks and 12 goats with scabies. The cattle divided into 4 groups (S1, S2, S3 and S4) while goats were divided into 3 groups (K1, K2, and K3) equally. For cattle with ticks group S1 received water (control group), while group S2, S3, and S4 received 1%, 5%, and 10% sour soup powder respectively. Ticks that fell to the ground and not engorged were collected and identified. Statistical analysis showed that all concentrations of sour soup were effective in paralyzing and or killing ticks of the genera Boophilus sp. and Dermacentor sp. but were not effective against Rhipicepalus sp. For goats with scabies, groups K1, K2, and K3 received 1, 5 and 10% sour soup powder respectively mixed with water applied to whole area of infected and uninfected skin surrounding infected area. Number of mites per cm2 before and after treatment was counted. Statistical analysis showed that 1, 5, and 10% sour soup powder effective in reducing the number of scabies mites on day 1 and 7 after treatment and were significantly different from those number of mites before treatment (P0.01). Statistical analysis also showed that no significant difference among concentration of sour soup seed powder in decreasing the number of mites (P0.05).
CORRELATION BETWEEN PROGESTERONE HORMONE CONCENTRATION AND NUMBER OF FETUSES OF ETAWA CROSSBRED GOAT IN DIFFERENT GESTATION PERIOD Syafruddin, Syafruddin; Rizal, Khairul; Rosmaidar, Rosmaidar; Melia, Juli; roslizawaty, roslizawaty; Zuhrawati, Zuhrawati; Rahmi, Erdiansyah; Abrar, Mahdi
Jurnal Kedokteran Hewan Vol 11, No 3 (2017): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v11i3.8687

Abstract

This study aimed to investigate the correlation between progesterone hormone concentration and number of fetus as well as the difference in progesterone hormone concentration from different gestation periods in Etawah crossbred (EC). Five EC goats used in this study were injected with 2 mL of 5.5 mg prostaglandin F2 (PGF2, Capriglandin) intramuscularly, with an interval of 10 days. Goats that showed symptoms of estrus were mated naturally with male goats. Blood samples were taken on the 7th, 14th, 21st, and 75th days of gestation. Progesterone hormone concentration was determined using enzyme linked immunosorbent assay (ELISA). The number of fetus was determined at 35th gestational day using ultrasonography (USG). Four out of 5 goats were found to have 1 fetus and 1 goat had 2 fetuses. The progesterone concentration on the 7th, 14th, 21st, and 75th days of gestation in goats with single fetus were 5.21, 7.78, 11.97, and 18.78 ng/mL, respectively, while in goat with two fetuses were 8.44, 14.53, 16.81, and 22.73 ng/mL, respectively. The correlation (r) between progesterone hormone concentration and number of fetus on the 7th, 14th, 21st, and 75th days of gestation were 0.442, 0.854, 0.592, and 0.757, respectively. It is concluded that progesterone concentrations are highly correlated to the number of fetus in each gestation period in EC goats.
Klinik Hewan Keliling Rumah Sakit Hewan Pendidikan Prof. Noerjanto Universitas Syiah Kuala [Mobile Veterinary Clinic of Prof. Noerjanto Hospital Teaching Veterinary Hospital of Universitas Syiah Kuala] Sayuti, Arman; Panjaitan, Budianto; Syafruddin, Syafruddin; Adam, Mulyadi; Thasmi, Cut Nila; Roslizawaty, Roslizawaty; Rosmaidar, Rosmaidar; Siregar, Tongku Nizwan; Armansyah, Teuku; Sutriana, Amalia; Aliza, Dwinna
Buletin Pengabdian Vol 4, No 2 (2024): Bull. Community. Serv.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/bulpengmas.v4i2.37290

Abstract

The long-term purpose of this community service is to support the autonomy of the university through independent income generation and to encourage the development of a culture of utilizing university research results for the community through the mobile veterinary clinic business carried out by Prof. Noerjanto Teaching Veterinary Hospital. To achieve above objectives, it was necessary to modify the existing clinic vehicle to include an operating room, mini-laboratory and pharmacy. The implementation of activities was carried out for five working days a week, by actively visiting smallholder livestock centers per village per day in the Aceh Besar areas. Services provided included livestock health consultation, treatment, vaccination (an effective measure as a form of protection for animals, synchronization of heat and artificial insemination, and assistance during birth. The diagnosis methods utilize the latest techniques, namely diagnosis and therapy techniques used in the field of veterinary medicine, which were the results of previous research. Mobile Clinic of Prof. Noerjanto's Teaching Veterinary Hospital had been modified by providing an operating table, mini laboratory, pharmacy, and repainting the car, thus increased the attractiveness of the community during the activities were carried out. Mass treatment of livestock in Aceh Besar district had reached the target which services covered five sub-districts. In conclusion, the mobile veterinary clinic in 2017 has successfully modified the clinic car and provided health services in 5 sub-districts in Aceh Besar District.