Claim Missing Document
Check
Articles

Found 3 Documents
Search
Journal : Sinteza

Gambaran Penjualan Obat Swamedikasi di Apotek Karomah Palangka Raya saat Pandemi Covid-19 Tahun 2021 Citrariana, Shesanthi; Paramawidhita, Risqika Yuliatantri
Sinteza Vol. 3 No. 1 (2023): February
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v3i1.7843

Abstract

Swamedikasi diartikan sebagai pemilihan dan pemanfaatan obat-obatan untuk mengobati gejala atau penyakit yang dikenali sendiri. Provinsi Kalimantan Tengah memiliki prevalensi swamedikasi yang tinggi yaitu 89,46%. Peningkatan minat masyarakat terhadap swamedikasi meningkat karena pandemi COVID-19. Penelitian ini bertujuan untuk melihat gambaran penjualan obat swamedikasi di Apotek Karomah saat pandemi COVID- 19 berlangsung. Pengumpulan data penjualan dilakukan dengan melihat pada SIM (Sistem Informasi Management) berbasis computer pada Juli – Agustus 2021. Hasil penelitian menunjukan bahwa tiga besar penjualan berdasarkan jenis obat di Apotek Karomah berupa Batuk&Flu sebanyak 1956 item (24,48%), Jamu&Minuman sebanyak 1482 item (18,55%), dan Alkes sebanyak 993 item (12,43%). Penjualan sepuluh besar (Top 10) berdasarkan item/ merk obat ditempati oleh komix batuk sebanyak 1236 item, madu TJ sebanyak 718 item, dan masker sebanyak 554 item. Total omzet penjualan pada Bulan Juli adalah Rp 49.068.000,- dan terlihat menurun pada Bulan Agustus Rp 43.944.000,-. Dari hasil penelitian ini dapat disimpulkan bahwa pandemi COVID-19 memberikan dampak penjualan obat swamedikasi di Apotek Karomah Kota Palangka Raya terutama obat-obat yang berkaitan dengan penurunan gejala COVID-19 dan peningkatan imunitas tubuh. 
Bahan Tambahan dalam Sediaan Tablet: Review Pratiwi, Puspa Dwi; Citrariana, Shesanthi; Gemantari, Baiq Maylinda
Sinteza Vol. 3 No. 2 (2023): August
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v3i2.17472

Abstract

Tablets are solid pharmaceutical dosage form without or with suitable excipients by press or compression manufacturing process. The excipient chosen can influence the product performance (physical properties and stability) and bioavailability. All excipients must be optimally selected to get the optimal formula of tablet dosage form. This article review aims to overview of excipient in tablet dosage form and their role in formulating tablet dosage form. this review article was written based on literature studies from electronic databases such as PubMed, ScienceDirect, and Google Scholar which contain related information using keyword in Indonesian or English use article published in 2013-2023. excipients in tablet dosage form are fillers or diluents, disintegrants, lubricants, preservatives, flavors, sweeteners, coloring, and coating agents. These excipients added to tablet dosage form to facilitating the process of manufacture tablet dosage form, increasing stability and effectiveness of active pharmaceutical ingredients in tablet. The conclusion of this review, there are many classification of tablet excipients which is different function to get compendial requirements of tablet dosage form.
Formulasi Pil Kunyit (Curcuma Longa L.) Kombinasi Sari Jeruk Limau Kuit (Citrus Hystrix Dc.) Sebagai Antioksidan Citrariana, Shesanthi; Muhammad Priyadi; Anograh R, Defilia; Rahmman, Sudarman; Febrianto, Yahya; Irawan, Ahmad; June N, Franz; Elphasa H, Shavira; Adistia P, Allaya
Sinteza Vol. 6 No. 1 (2026): February
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v6i1.32965

Abstract

Turmeric contains the active compound curcumin, which has been studied for its various biological activities, including antioxidant, anti-inflammatory, antimicrobial, and immunomodulatory properties. Kaffir lime is a plant commonly found on the island of Borneo and is used in traditional medicine and culinary flavors. Kaffir lime fruit and leaves contain various bioactive compounds, such as flavonoids (hesperidin, naringenin), essential oils (citronellal, limonene), and vitamin C. Flavonoids are known to have antioxidant and anti-inflammatory effects that can boost the immune system. Pills are one of the oldest dosage forms in the pharmaceutical world and are still relevant, especially for herbal preparations due to their ease of manufacture and stability. This study aims to formulate pill preparations by combining turmeric and lime juice. The method used is wet granulation to make pills with varying turmeric concentrations, namely F1 0.26% and F2 0.52% using polyvinyl alcohol as a binder. Physical evaluations include water content, weight uniformity, pH, and disintegration time tests. The pills were then tested for antioxidant activity against DPPH. The results showed that the water content of F1 pills was 4.06% and F2 pills 3.75%, pill weight uniformity with RSD value criteria of F1 was 0.21% and F2 pills 3.40%, the average pH of F1 was 6.32 and F2 pills 6.22, and the disintegration time of F1 was 30 minutes and F2 pills 8.26 minutes. The results of the antioxidant activity of the pill preparations showed that the F1 IC50 was 6.36 ppm and the F2 IC50 was 5.53 ppm. From the results obtained, it can be concluded that F2 pill preparations have good physical properties and potential antioxidant activity.
Co-Authors Adi, Mika Adistia P, Allaya Ahmad Irawan, Ahmad Akhmad Kharis Nugroho Alfanaar, Rokiy Anograh R, Defilia Ardi Akbar Tanjung Ari Wibowo Arsana, Mu afa Arsana, Mu’afa Purwa Arsana, Mu’afa Purwa Awalul Fatiqin Awumistiko Awumistiko Ayu, Regina Wahyudyah Sonata Ayuchecaria, Noverda Baiq Maylinda Gemantari Bambang Hernawan Nugroho Chuchita Dea Betriksia Decenly Decenly Decenly, Decenly Defilia Anogra Riani Defilia Anograh Riani Desindria, Galang Rizdho Efriyana Oksal Efriyana Oksal Elphasa H, Shavira Emma Ayudia Noriadita Endang Lukitaningsih Erni Dwi Puji Setyowati, Erni Dwi Puji Fatiqin, Awalul Fauziah, Anisa Rahma Gerung, Jenny Blessia Gintoro, Atilla Dian Dewanti Gunawan, Yohanes E Gunawan, Yohanes Edy Guntur Satrio Pratomo Halida Suryadini Haq, Muhammad Hasanul Ita Nurma Sari Ita Nurma Sari Jipasca, Elon June N, Franz Kalalinggi, Septaria Yolan Krissilvio, Eka Jonathan Kurniawan, Yehezkiel Steven M Munawwarah Ma'rifah, Siti Mariasa, Joice Cleriska Melliani Melliani Muhammad Dawam Muhammad Priyadi Mu’afa Purwa Arsana Mu’afa Purwa Arsana Ngazizah, Febri Nur Nur Hidayat Oktavia Indrati, Oktavia Parametta, Vidya Puspa Dwi Pratiwi Puspa Dwi Pratiwi Rahman, Ansori Rahman, Sudarman Rahmman, Sudarman Reny Nadya Oktari Riani, Defilia Risqika Yulia Tantri Paramawidhita Rizki Rachmad Saputra Rokiy Alfanaar Shodri, Muhammad Rifqi Simajuntak, Ruth Riama Siti Sunariyati Sulistia, Tiya Thathit Suprayogi Thathit Suprayogi Tri Megawati Wahyu Nugroho Wilda, Robiatul Witari Yahya Febrianto Yahya Febrianto Yohanes Edy Gunawan Yosaeunike, Vitatani Yulita, Elia Zimon Pereiz