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Mekanisme Molekuler Muscle Disuse Atrophy Zulfahmidah, Zulfahmidah; Safei, Imran
Wal'afiat Hospital Journal Vol. 4 No. 1 (2023): Wal'afiat Hospital Journal
Publisher : Rumah Sakit Ibnu Sina, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/whj.v4i1.102

Abstract

Kehilangan massa otot rangka sering terjadi sebagai respons terhadap imobilisasi sendi dan tirah baring, serta diinduksi oleh ketidak aktifan dari otot tersebut. Atrofi yang diinduksi oleh kurangnya aktivitas akan mempengaruhi setiap individu dalam hidupnya, dan dapat melemahkan terutama pada orang tua. Saat ini tidak ada terapi yang baik untuk mengobati disuse atrofi otot dapat disebabkan karena kurangnya pemahaman tentang mekanisme seluler dan molekuler yang bertanggung jawab untuk induksi dan pemeliharaan atrofi otot. Di dalam review ini akan dibahas mekanisme molekuler yang terlibat pada atropi otot disuse
THE EFFECT OF LIFESTYLE ON SKIN AGING Sandewa, Ele; Vitayani, Sri; Namirah, Hanna Aulia; Waspodo, Nurelly Noro; Safei, Imran
International Journal of Health Science & Medical Research Vol 5, No 2 (2026): August 2026
Publisher : UNG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/ijhsmr.v5i2.37307

Abstract

Skin aging is a natural process influenced by intrinsic and extrinsic factors, with lifestyle-related exposures such as ultraviolet radiation, pollution, poor diet, smoking, alcohol consumption, and inadequate sleep contributing to its acceleration. However, research examining the comprehensive impact of lifestyle on objectively measured skin aging parameters in rural Indonesian populations remains limited. The novelty of this study lies in its focus on a rural community in Eastern Indonesia, combining a validated lifestyle assessment with objective clinical skin analysis to generate context-specific evidence. This study aimed to determine the influence of lifestyle on skin aging among individuals aged 30–40 years in Lipulalongo Village, Banggai Laut Regency, Central Sulawesi. An observational analytic study with a cross-sectional design was conducted on 60 respondents selected through simple random sampling. Lifestyle was assessed using the Lifestyle Assessment Questionnaire 2025, while skin aging was measured using the Vision Skin Analyzer based on hydration, elasticity, wrinkles, and pigmentation parameters. Data were analyzed using univariate and bivariate methods, with the Spearman rank correlation test applied due to the ordinal nature of lifestyle data. The results showed that most respondents had lifestyles requiring improvement (61.7%) or were at high risk (38.3%), with skin conditions predominantly classified as normal (28.3%) and slightly moist (21.7%). A significant moderate correlation was found between lifestyle and skin aging (P-value 0.001; r = 0.514). In conclusion, lifestyle significantly influences skin aging, highlighting the importance of targeted health education to promote healthier behaviors in similar rural populations
Hubungan Kebiasaan Berolahraga Dengan Tingkat Stres Pada Mahasiswa Kedokteran Universitas Muslim Indonesia Angkatan Tahun 2024 Burhan, Khairun Nisaa; Wahyu, Sri; Iskandar, Darariani; Safei, Imran; Jaya, Muhammad Alim
MAHESA : Malahayati Health Student Journal Vol 6, No 5 (2026): Volume 6 Nomor 5 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i5.22725

Abstract

ABSTRACT Stress is a common problem experienced by medical students and can impact physical health, psychological well-being, and academic achievement. This study aims to analyze the relationship between exercise habits and stress levels among students from the Faculty of Medicine, Muslim University of Indonesia, Class of 2024. The study design used an observational analytic approach with a cross-sectional approach. The study sample consisted of 226 students, determined through total sampling based on inclusion criteria. The instruments used included an exercise habits questionnaire and the DASS-42 to measure stress levels. Univariate analysis showed that the majority of respondents had moderate exercise habits 186 respondents (82.3%) and 122 respondents (54.0%) had normal stress levels. Bivariate analysis using the Chi-Square test yielded a p-value of 0.513 (p 0.05), indicating no significant relationship between exercise habits and stress levels. Thus, although exercise has important health benefits, exercise habits were not directly associated with stress levels among medical students in this study. Keywords: Exercise Habits, Stress Levels, Medical Students.  ABSTRAK Stres merupakan permasalahan yang sering dialami oleh mahasiswa kedokteran dan dapat berdampak pada kesehatan fisik, kondisi psikologis, serta pencapaian akademik. Penelitian ini bertujuan untuk menganalisis hubungan antara kebiasaan berolahraga dengan tingkat stres pada mahasiswa Fakultas Kedokteran Universitas Muslim Indonesia angkatan 2024. Desain penelitian yang digunakan adalah observasional analitik dengan pendekatan cross-sectional. Sampel penelitian berjumlah 226 mahasiswa yang ditentukan melalui metode total sampling berdasarkan kriteria inklusi. Instrumen yang digunakan meliputi kuesioner kebiasaan olahraga dan DASS-42 untuk mengukur tingkat stres. Hasil analisis univariat menunjukkan bahwa mayoritas responden memiliki kebiasaan olahraga pada kategori sedang 186 orang (82,3%) serta berada pada tingkat stres normal 122 orang (54,0%). Analisis bivariat menggunakan uji Chi-Square menghasilkan nilai p = 0,513 (p 0,05), yang menunjukkan tidak terdapat hubungan signifikan antara kebiasaan olahraga dan tingkat stres. Dengan demikian, meskipun olahraga memiliki manfaat yang penting bagi kesehatan, kebiasaan berolahraga tidak terbukti berhubungan langsung dengan tingkat stres mahasiswa kedokteran dalam penelitian ini. Kata Kunci: Kebiasaan Berolahraga, Tingkat Stres, Mahasiswa Kedokteran.