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Journal : Medfarm: Jurnal Farmasi dan Kesehatan

The Determinants of Drug-Resistant Tuberculosis Incidence at the Special Lung Hospital, Health Department of the Provincial Government of North Sumatera, 2021-2024 Dalimunthe, Mawaddah Sri Rezeki; Susanti, Nofi; Aidha, Zuhrina; Batubara, Abdul Karim
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i1.539

Abstract

Along with the increase in tuberculosis (TB) cases, there has also been a rise in the number of Drug-Resistant Tuberculosis (DR-TB) cases, which poses a serious threat to global TB control efforts. Globally, there are 400,000 DR-TB cases according to the WHO report in 2024, with Indonesia contributing 7.4% of the total cases. In North Sumatra, the incidence of DR-TB cases reached 54%. This study aims to analyze and identify the factors influencing the incidence of DR-TB among DR-TB patients at the Special Lung Hospital of the Provincial Government of North Sumatra. The study uses a quantitative approach with a case-control design utilizing secondary data from the SITB application at the Special Lung Hospital of the Provincial Government of North Sumatra from 2021-2024. The sample consists of 204 individuals with a 1:1 ratio, comprising 102 individuals with DR-TB and 102 controls with non-DR-TB. The sampling technique used is purposive sampling. This study sets DR-TB incidence as the dependent variable, while independent variables include sex, employment status, age, treatment outcome, access to health service facilities, residence, contact examination, TB treatment history, diagnosis type, diabetes mellitus status, and HIV status. Data were analyzed using three tests: univariate analysis, bivariate analysis, and multivariate analysis with the use of statistical software version 22. The results show that factors significantly influencing DR-TB incidence include age (CI 95%: 4.7 [2.3-9.5]), employment (CI 95%: 3.4 [1.7-6.6]), and a history of previous TB treatment (CI 95%: 14.7 [5.5-39]).
Co-Authors Abdi Mubarak Syam Abidin, Syahrul Adellia, Mayranda Afriyani, Wilda Ahyar, Amrul Albagani, Fauzan Reynaldi Ali, M.Nasihudin Amanda, Dea Amanda, Mutia Amin, Afriadi Awaliyah, Afsah Azhar, Anang Anas Br Rambe, Suci Wahyu Tami Budi Prasetyo Budiman Budiman Dalimunthe, Mawaddah Sri Rezeki Damayanti, Purba Eka Darmayanti, Lisa Daulay, Ardiani Deni, Indira Fatra Eliska, Eliska Hajjah, Siti Hasan Sazali Hesti, Yola May Hsb, Fathi Farich Husnah, Asmaul Ivanka, Chika Maya Jamil, Khoirul Khairy, Rafli Khumaira, Jihan Oka Lingga, Iyana Monina Lubis, Fatma Sri Ramadhan Lubis, Fauziah M. Nasihudin Ali Monang, Sori Mufida, Dwi Nanda Muhaini, Muhaini Muhammad Yusup Muslih Fathurrahman Nafisah, Mutia Nainggolan, Jelita Tua Naldo, Jufri Naldo Nasution, Kartika Amelia Nasution, Mhd. Fatih Fauzan Nofi Susanti Nurhumairoh, Siti Oka Merta Jayano, I Made P, Indira Fatra Deni pangesti, Mirawati idi Pinem, Radiyah Hanum Pradana*, Gusti Riza Purwaningtyas, Franindya Putri, Audina Raissa Amanda Putri Ramadhanti, Tengku Maura Safa Ramadhina, Widya Rambe, Sabda Firmansyah Ridho, Raja Ahmad Rifky Fansuri, Muhammad Riski, Israq Ritonga, Elfi Yanti Rohani, Laila Sabriyanti, Aina Sari, Dina Mei Sihombing, Mifta Huljannah Siregar, Ihza Nabila Sitepu, Khairani Akmal Siti Qomariah, Siti Solihah Titin Sumanti, Solihah Titin Suyono, Hanny Chairany Syafran Arrazy Syahfitri, Dini Trisna, Nabilla Fairus Izzati Eka Tusadiah, Halimah Viona, Intan Dilla Yanti, Rizki Febri Yusniah, Yusniah Zainun, Zainun Zuhrina Aidha