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HUBUNGAN BERAT BADAN LAHIR DAN DIABETES GESTASIONAL DENGAN KEJADIAN HIPOGLIKEMIA NEONATUS DI RSUD KOTA MATARAM Muhammad Rezki Al-Ayyubi; I Putu Dedy Arjita; Muhammad Ashhabul Kahfi Mathar; Ananta Fittonia Benvenuto
Indonesian Journal of Health Research Innovation Vol. 3 No. 1 (2026): Indonesian Journal of Health Research Innovation
Publisher : Yayasan Menawan Cerdas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64094/zejw2m96

Abstract

Hipoglikemia neonatus merupakan salah satu masalah metabolik pada bayi baru lahir yang dapat terjadi tanpa gejala dan berpotensi menimbulkan komplikasi bila tidak ditangani. Kejadian hipoglikemia neonatus dipengaruhi oleh berbagai faktor, termasuk berat badan lahir dan kondisi maternal seperti diabetes gestasional.Tujuan penelitian untuk mengetahui hubungan berat badan lahir dan diabetes gestasional dengan kejadian hipoglikemia neonatus di RSUD Kota Mataram. Penelitian kuantitatif analitik observasional dengan rancangan cross-sectional. Penelitian dilaksanakan pada Oktober 2023 di RSUD Kota Mataram menggunakan data rekam medis kelahiran hidup tahun 2022. Teknik pengambilan sampel menggunakan purposive sampling dengan jumlah sampel 103 neonatus. Analisis bivariat dilakukan untuk menilai hubungan antarvariabel dengan tingkat signifikansi 0,05. Tidak terdapat hubungan yang signifikan antara berat badan lahir dan kejadian hipoglikemia neonatus (p=0,052). Terdapat hubungan yang signifikan antara diabetes gestasional dan kejadian hipoglikemia neonatus (p=0,001). Diabetes gestasional berhubungan signifikan dengan kejadian hipoglikemia neonatus, sedangkan berat badan lahir tidak menunjukkan hubungan yang signifikan dengan hipoglikemia neonatus di RSUD Kota Mataram.
UJI DAYA HAMBAT EKSTRAK BATANG KAYU SECANG (Caesalpinia Sappan L.) TERHADAP BAKTERI Escherichia Coli Dharmayanti, Ni Made Dwi; Arjita, I Putu Dedy
JURNAL KEDOKTERAN Vol. 4 No. 1 (2018)
Publisher : Fakultas Kedokteran Universitas Islam Al-Azhar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (60.304 KB) | DOI: 10.36679/kedokteran.v4i1.60

Abstract

Escherichia coli merupakan bakteri gram negatif berbentuk batang dalam sel tunggal atau berpasangan. Escherichia coli termasuk anggota flora normal dalam usus dan dapat menjadi patogen bila mencapai jaringan di luar jaringan intestinal. Mengingat obat-obatan kimiawi banyak yang menyebabkan resistensi dan efek samping, para ahli farmakologi mulai mengembangkan pengobatan dengan bahan-bahan yang tradisional seperti tanaman secang (Caesalpinia sappan L.) yang bermanfaat sebagai antibakteri (Katno, 2008).Tujuan penelitian ini adalah untuk mengetahui daya hambat ekstrak batang kayu secang (Caesalpinia sappan L.) terhadap bakteri Escherichia coli. Penelitian ini merupakan jenis penelitian True Experiment dengan rancangan Posttest dengan Kelompok Kontrol (Posttest Only Control Group Design), menggunakan Rancangan Acak Lengkap (RAL) dengan 24 unit percobaan dan 4 kali ulangan. Sampel penelitian adalah ekstrak batang kayu secang (Caesalpinia sappan L) dengan konsentrasi 10%, 20%, 30% dan 40%, 2 kelompok kontrol terdiri dari kontrol positif ciprofloxacin dan kontrol negatif aquades. Daya hambat diperoleh berdasarkan pengukuran zona hambat dan data yang diperoleh dianalisis menggunakan uji One Way Anova.Hasil penelitian zona hambatan untuk Escherichia coli pada konsentrasi 10% (0 mm); 20% (0 mm); 30% (0 mm) dan 40% (0 mm). Hasil uji Kruskal Wallis diperoleh nilai signifikan yakni 1,000 lebih besar dari p value: 0,05 sehingga dapat dinyatakan bahwa ekstrak batang kayu secang (Caesalpinia sappan L.) tidak memiliki daya hambat terhadap pertumbuhan bakteri Escherichia coli
Efektivitas Kombinasi Ekstrak Etanol Daun Kirinyuh (Chromolaena Odorata) dan Daun Talas (Colocasia Esculenta) terhadap Daya Hambat Pertumbuhan Methicillin-Resistant Staphylococcus Aureus (MRSA) Dienda Rara Nursoleha; I Putu Dedy Arjita; Sabariah Sabariah; Ety Retno Setyowati
Malahayati Nursing Journal Vol 8, No 4 (2026): Volume 8 Nomor 4 (2026)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v8i4.24121

Abstract

ABSTRACT Methicillin-Resistant Staphylococcus aureus (MRSA) infection has resulted in an increase of the death rate due to Antimicrobial Resistance around the world, one of it is Indonesia. The treatment of MRSA infections mostly uses synthetic antibacterial drugs. However, currently many synthetic drugs are getting resistance, that allowing MRSA infections out of control. One of the attempts to solve this problem is to use natural ingredients such as Chromolaena odorata and Colocasia esculenta plants which have been proven to have antimicrobial effects against some bacteria. This research aims to test the effectiveness of the combination of Chromolaena odorata and Colocasia esculenta extract with ethanol in inhibiting the growth of MRSA. This research method uses true experimental using the Cup-plate technique/well diffusion method. The number of experimental units was 28 that divided into 7 groups with a ratio of 1:0, 1:1, 1:2, 2:1, 0:1, positive control of Vancomycin 30ug/disk, negative control of ethanol 95%. From the antibacterial test, there were results a very strong categories in combination of 1:0, 1:1, 1:2, and 2:1 ethanol extract of Chromolaena odorata and Colocasia esculenta with inhibitory zone diameters of 20 mm, 20.875 mm, 21.25 mm, and 22.125 mm. Meanwhile, the ratio of 0:1 is unable to inhibit MRSA. The results of the Mann-Whitney test showed that there was no significant difference between the ratio of 1:0, 1:1, 1:2, and 2:1 with the positive control, meanwhile the ratio of 0:1 has a significant difference. In this study, there was an effectiveness on the combination of Chromolaena odorata and Colocasia esculenta extract with ethanol in the ratio of 1:0, 1:1, 1:2, and 2:1 that inhibited the growth of MRSA.  Keywords: Antibacteria, Combination, MRSA.  ABSTRAK Infeksi Methicillin-Resistent Staphylococcus aureus (MRSA) mengakibatkan terjadinya peningkatan angka kematian akibat Antimicrobial Resistance diseluruh dunia, salah satunya di Indonesia. Pengobatan infeksi MRSA sebagian besar menggunakan obat-obatan antibakteri sintetik. Namun, saat ini obat-obatan sintetik banyak mengalami resistensi sehingga memungkinkan infeksi MRSA semakin tidak terkendali. Salah satu upaya untuk mengatasi hal tersebut adalah dengan menggunakan bahan alami seperti tanaman Chromolaena odorata dan Colocasia esculenta yang tebukti memiliki efek antimikroba terhadap beberapa bakteri. Penelitian ini bertujuan untuk menguji efektivitas kombinasi ekstrak etanol Chromolaena odorata dan Colocasia esculenta dalam menghambat pertumbuhan MRSA. Metode penelitian ini menggunakan true experimental menggunakan metode difusi Cup-plate technique/sumuran. Jumlah unit percobaan sebanyak 28 pada 7 kelompok dengan perbandingan 1:0, 1:1, 1:2, 2:1, 0:1, kontrol positif Vankomisin 30ug/disk, kontrol negatif etanol 95%. Dari uji antibakteri tersebut terdapat hasil pada kombinasi 1:0, 1:1, 1:2, dan 2:1 ekstrak etanol Chromolaena odorata dan Colocasia esculenta memiliki diameter zona hambat 20 mm, 20,875 mm, 21,25 mm, dan 22,125 mm termasuk kategori sangat kuat. Sedangkan pada perbandingan 0:1 tidak mampu menghambat MRSA. Hasil uji Mann-Whitney menunjukkan bahwa tidak terdapat perbedaan secara signifikan pada perbandingan 1:0, 1:1, 1:2, dan 2:1 terhadap kontrol positif. Sedangkan perbandingan 0:1 memiliki perbedaan secara signifikan. Pada penelitian ini terdapat efektivitas kombinasi ekstrak etanol Chromolaena odorata dan Colocasia esculenta pada perbandingan 1:0, 1:1, 1:2, dan 2:1 dalam menghambat pertumbuhan MRSA Kata Kunci: Antibakteri, Kombinasi, MRSA.
Noni (Morinda Citrifolia) Ethanol Extract Lowered Blood Glucose Levels, Increased Glutathione Peroxidase Activity, And Decreased Malondialdehyde in White Rats Model of Diabetes I Putu Dedy Arjita; I Putu Bayu Agus Saputra; Dhika Juliana Sukmana
Jurnal Penelitian Pendidikan IPA Vol 9 No 12 (2023): December
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i12.6076

Abstract

Diabetes mellitus can increase oxidative stress and damage cells. Noni fruit has antibacterial, antifungal, antitumor, analgesic, hypotensive, and anti-inflammatory benefits, can boost immunity, and has antioxidant content. Noni contains phenolic compounds (anthraquinones, acuities, asperulosides, and scopoletin), organic acids (capric and caprylic acids), and alkaloids (xeronine). The effect of noni ethanol extract can significantly reduce blood glucose (P<0.05) of the T2 group (177.00±137.78) and T3 (159.40±86.53) when compared to the C+ group (511.00±131.45). The T1 group (387.40±170.06) had no significant difference (P>0.05) when compared to the C+ group (511.00±131.45), but there was a decrease in the average yield at T1 (387.40±170.06). Serum malondialdehyde (MDA) examination showed a significant decrease (p<0.05) in T1 (1188.32±93.41), while in T2 (1385.35±38.65) and T3 (1460.32±42.51) was not significant (p<0.05). Examination of serum glutathione peroxidase (GPX) showed a significant decrease in T1 (119.97±37.45), there was a decrease in GPX levels, while in the T2 group (236.14±6.05) and T3 (185.24±43.07), there was no decrease. Noni ethanol extract can lower blood glucose levels, reduce Malondialdehyde levels, and prevent increased activity of the enzyme glutathione peroxidase. Flavonoid compounds in noni ethanol extract can avoid increased blood glucose and reduce free radicals formed due to hyperglycemia conditions.  
Potensi senyawa turunan flavonoid dalam menjadi inhibitor enzim HMG-Coa reductase kandidat obat h I Putu Bayu Agus Saputra; I Putu Dedy Arjita
Jurnal Penelitian Pendidikan IPA Vol 10 No 5 (2024): May
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i5.6237

Abstract

Cardiovascular disease (CVD) is a disease that causes death in the world. Behavioral risk factors are crucial in dealing with CVD disease. High levels of cholesterol in the blood are associated with hypercholesterolemia. It can increase the risk of CVD disease. The HMG-CoA reductase enzyme is an enzyme that plays a role in cholesterol synthesis. It will convert the HMG-CoA compound into the mevalonate. Inhibition of this enzyme can reduce cholesterol synthesis because it inhibits the formation of mevalonate, which is the initial stage of cholesterol synthesis. Herbal compounds are compounds produced by plants. It has good benefits for the body. Flavonoid compounds can be beneficial for health. Molecular docking is a method used to determine the binding affinity and interaction values ​​of the enzyme protein interaction with the ligand to be bound. The results of Apigenin binding affinity values is -7.7 kcal/mol, Luteolin is -8 kcal/mol, Quercetin is -8.2 kcal/mol, Kaempferol is -7.4 kcal/mol, Phloretin is -6.8 kcal/mol, Chalconaringenin is -6.9 kcal/mol, Cyanidin is -7.9 kcal/mol, Delphinidin is -7.8 kcal/mol, Hesperetin is -7.7 kcal/mol, Narigenin is -7.8 kcal/mol, Daidzein is -6.8 kcal/mol, Genistein is -7 kcal/mol, Rutin is -9.2 kcal/mol, Taxifolin is -8 kcal /mol, Diosmetin is -7.6 kcal/mol, and its native ligand Rosuvastatin is -8.5 kcal/mol. Flavonoid derivative compounds can bind to the HMG-CoA reductase enzyme. They can be candidates for antihyperlipidemia drugs.
Hubungan Pengetahuan, Sikap, dan Tingkat Pendidikan Terhadap Perilaku Pencegahan Anemi Pada Remaja Putri di Desa Malaka Baiq Woni Aulia Permadi Putri; Ayu Anulus; Nisia Putri Rahayu; I Putu Dedy Arjita
Midwifery Student Journal (MS Jou) Vol. 4 No. 2 (2025): Midwifery Student Journal (MS Jou)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/msjou.v4i2.71

Abstract

Latar Belakang:  Perilaku pencegahan anemia masuk pada jenis perilaku pemeliharaan kesehatan (health maintenance), perilaku ini merupakan perilaku atau usaha-usaha seseorang untuk memelihara atau menjaga kesehatan agar tidak sakit dan usaha untuk penyembuhan bila sakit. Menurut Green Lawrence dalam teori ini bahwa kesehatan seseorang dipengaruhi oleh dua faktor yakni faktor perilaku dan faktor diluar perilaku. Faktor perilaku dipengaruhi oleh 3 hal yakni Predisposing factor, Reinforcing factor dan Enabling factor. Tujuan:  Penelitian ini dilakukan untuk mengetahui hubungan Pengetahuan, Sikap dan Tingkat Pendidikan terhadap Perilaku Pencegahan Anemia pada remaja putri di Desa Malaka. Metode:  Jenis penelitian yang digunakan adalah analitik observasional dengan menggunakan rancangan penelitian cross sectional study. Teknik pengambilan sampel menggunakan purposive sampling. Penelitian ini dilaksanakan di Desa Malaka. Data yang diperoleh dianalisis dengan uji chi-square. Batas nilai signifikansi adalah p-value <0,05. Hasil Penelitian: Karakteristik responden sebagian besar di dominasi oleh remaja putri usia 10-15 tahun, dan pendidikan SMP.  Pada analisis bivariat didapatkan hasil masing-masing variabel (p-value <0,05) dengan nilai  hubungan pengetahuan dengan perilaku pencegahan anemia  ( < 0,001), hubungan sikap dengan perilaku pencegahan anemia (< 0,001), hubungan tingkat pendidikan dengan perilaku pencegahan anemia (< 0,001). Kesimpulan: Berdasarkan hasil uji statistik yang dilakukan, terdapat hubungan  antara pengetahuan, sikap, dan tingkat pendidikan terhadap perilaku pencegahan anemia pada remaja putri di desa malaka. Abstract Background : Anemia prevention behavior is included in the type of health maintenance behavior, this behavior is a person's behavior or efforts to maintain or maintain health so as not to get sick and efforts to heal if sick. According to Green Lawrence, in this theory, a person's health is influenced by two factors, namely behavioral factors and factors outside of behavior. Behavioral factors are influenced by 3 things, namely Predisposing factors, Reinforcing factors and Enabling factors. Objective : This research was conducted to determine the relationship between knowledge, attitudes and education level on anemia prevention behavior among young women in Malaka Village. Method: The type of research used is observational analytics using a cross sectional study research design. The sampling technique uses purposive sampling. This research was carried out in Malaka Village. The data obtained were analyzed using the chi-square test. The significance limit is p-value <0.05. Results : The characteristics of respondents were mostly dominated by young women aged 10-15 years, and with junior high school education. In the bivariate analysis, the results of each variable were obtained (p-value <0.05) with a value of the relationship between knowledge and anemia prevention behavior (<0.001), the relationship between attitudes and anemia prevention behavior (<0.001), the relationship between education level and anemia prevention behavior (<0.001). < 0.001). Conclusion: Based on the results of statistical tests carried out, there is a relationship between knowledge, attitudes and level of education on anemia prevention behavior among young women in Malacca village.  
Hubungan Konsumsi Sugar Sweetened Beverages, Indeks Massa Tubuh (IMT), dan Aktivitas Fisik dengan Kadar Gula Darah Sewaktu Pada Penderita Diabetes Melitus Tipe 2 di RSUD Kota Mataram I Putu Tegar Cahyadi Nanda Sudarta; Setio Rini; I Putu Dedy Arjita; Ana Andriana
MAHESA : Malahayati Health Student Journal Vol 5, No 7 (2025): Volume 5 Nomor 7 (2025)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v5i7.18782

Abstract

ABSTRACT Public health problems are complex problems that are the result of various environmental problems that are natural or artificial caused by humans, socio-culture, behavior, population, genetics and so on. According to the World Health Organization (WHO) in the last 3 decades the prevalence of type 2 DM has increased significantly. Not only in developed countries, developing countries such as Indonesia have a high prevalence of type 2 DM. Indonesia is ranked 7th as the country with the highest incidence of DM in the world. The purpose of this study was to determine the relationship between consumption of sugar-sweetened beverages, body mass index (BMI) and physical activity with random blood sugar levels in type 2 DM patients at Mataram City Hospital. This type of research is an observational analytical quantitative study with a cross-sectional study design. Sugar-sweetened beverages with random blood sugar levels with a P value of 0.001 (P value ≤ 0.05).. Body mass index (BMI) with random blood sugar levels with a P value of 0.908 (P value 0.05). Physical activity with random blood sugar levels with a P value of 0.002 (P value ≤ 0.05). There is a significant relationship between consumption of artificially sweetened beverages and random blood sugar levels in patients with type 2 diabetes mellitus at RSUD Kota Mataram. There is no significant relationship between body mass index (BMI) and random blood sugar levels in patients with type 2 diabetes mellitus at RSUD Kota Mataram. There is a significant relationship between physical activity and random blood sugar levels in patients with type 2 diabetes mellitus at RSUD Kota Mataram. Keywords: Artificially Sweetened Beverages, Body Mass Index (BMI), Physical Activity, Blood Sugar Levels, Type 2 Diabetes Mellitus   ABSTRAK Masalah kesehatan masyarakat adalah masalah kompleks yang merupakan resultan dari berbagai masalah lingkungan yang bersifat alamiah maupun buatan yang disebabkan oleh manusia, sosial budaya, perilaku, populasi penduduk, genetika dan sebagainya. Menurut World Health Organization (WHO) dalam 3 dekade terakhir prevalensi DM tipe 2 meningkat secara signifikan. Tidak hanya di negara maju, negara berkembang seperti Indonesia memiliki prevalensi tinggi untuk penyakit DM tipe 2. Indonesia menempati posisi ke 7 sebagai negara dengan angka kejadian DM tertinggi di dunia. Tujuan dari penelitian ini untuk mengetahui hubungan konsumsi sugar sweetened beverages, indeks massa tubuh (IMT) dan aktivitas fisik dengan kadar gula darah sewaktu pada penderita DM tipe 2 di RSUD Kota Mataram. Jenis penelitian ini adalah penelitian kuantitatif analitik observasional dengan rancangan penelitian yang digunakan adalah cross sectional study. Sugar sweetened beverages dengan kadar gula darah sewaktu dengan nilai P-value adalah 0.001(P-value ≤ 0,05). Indeks massa tubuh (IMT) dengan kadar gula darah sewaktu dengan nilai P-value adalah 0.908 (P-value 0,05). Aktivitas fisik dengan kadar gula darah sewaktu dengan nilai P-value adalah 0.002 (P-value ≤ 0,05). Ada hubungan signifikan antara konsumsi sugar sweetened beverages dengan kadar gula darah sewaktu pada penderita DM tipe 2 di RSUD Kota Mataram. Tidak ada hubungan signifikan antara indeks massa tubuh (IMT) dengan kadar gula darah sewaktu pada penderita DM tipe 2 di RSUD Kota Mataram. Ada hubungan signifikan antara aktivitas fisik dengan kadar gula darah sewaktu pada penderita DM tipe 2 di RSUD Kota Mataram. Kata Kunci: Sugar Sweetened Beverages, Indeks Massa Tubuh (IMT), Aktivitas  Fisik, Kadar Gula Darah, Diabetes Melitus Tipe 2
Antibacterial Effectiveness of A Combination of Binahong (Anredera cordifolia) and Soursop (Annona muricata) Leaf Extract on The Growth of Escherichia coli in Vitro Agna Shailla Monica Wiranty; I Putu Dedy Arjita; Ety Retno Setyowati
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.11504

Abstract

The high incidence of diarrhea and the increasing resistance of Escherichia coli to various first-line antibiotics has prompted the search for safer and more effective antibacterial alternatives. Herbal plants such as binahong leaves and soursop leaves are known to contain secondary metabolites with antibacterial potential. This study aims to determine the antibacterial effectiveness of a combination of binahong and soursop leaf extracts on the growth of Escherichia coli in vitro and to determine the most effective combination concentration. This study was a laboratory experimental study with a true experimental design, then tested against Escherichia coli using the agar diffusion method. Statistical analysis was performed using the Kruskal–Wallis test and continued with the Mann–Whitney test. The results showed that the combination of binahong and soursop leaf extracts was able to inhibit the growth of Escherichia coli at all concentrations tested. There was a statistically significant difference in the diameter of the inhibition zone between treatment groups (p < 0.05). The combination of extracts at a concentration of 50% showed more optimal inhibitory activity than other concentrations, which is thought to be influenced by the interaction of the active compounds in both extracts. In conclusion, the combination of binahong and soursop leaf extracts has antibacterial effectiveness against the growth of Escherichia coli in vitro and has the potential to be developed as a natural antibacterial alternative.
Hubungan Usia, Diabetes Melitus, dan Hipertrigliseridemia dengan Tipe Stroke di RSUD Kota Mataram Pande Made Yoga Adi Dwipayana; Rohmania Setiarini; Sukandriani Utami; I Putu Dedy Arjita
MAHESA : Malahayati Health Student Journal Vol 6, No 9 (2026): Volume 6 Nomor 9 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i9.24754

Abstract

ABSTRACT Stroke is a leading cause of death and disability worldwide and represents a significant public health problem in Indonesia. Clinically, stroke is classified into non-hemorrhagic stroke and hemorrhagic stroke. This study aimed to analyze the relationship between age, diabetes mellitus, and hypertriglyceridemia with stroke type at Mataram City Regional General Hospital (RSUD Kota Mataram). This study was an analytical observational study with a cross-sectional design using medical record data of hospitalized stroke patients at RSUD Kota Mataram. The dependent variable was stroke type, classified into non-hemorrhagic and hemorrhagic stroke. The independent variables included age, diabetes mellitus, and hypertriglyceridemia. A total of 100 samples were included in the study. The results showed that 59% of patients were in the adult group and 41% were in the elderly group. Diabetes mellitus was found in 51% of patients, and hypertriglyceridemia in 43% of patients. Bivariate analysis demonstrated a significant association between age, diabetes mellitus, and hypertriglyceridemia with stroke type. Multivariate analysis showed that age had a significant effect on stroke type, while diabetes mellitus and hypertriglyceridemia increased the risk of certain stroke types. The risk factors influencing stroke type include age, diabetes mellitus, and hypertriglyceridemia. Keywords: Age, Diabetes Mellitus, Hypertriglyceridemia, Stroke Type.  ABSTRAK Stroke merupakan penyebab utama kematian dan kecacatan di dunia serta menjadi masalah kesehatan masyarakat yang signifikan di Indonesia. Secara klinis, stroke diklasifikasikan menjadi stroke non hemoragik dan stroke hemoragik. Tujuan penelitian ini dilakukan untuk menganalisis hubungan usia, diabetes melitus dan hipertrigliseridemia dengan tipe di RSUD Kota Mataram. Metode penelitian ini merupakan penelitian observasional analitik dengan desain cross sectional menggunakan data rekam medis pasien stroke rawat inap di RSUD Kota Mataram. Variabel dependen adalah tipe stroke yang diklasifikasikan menjadi stroke non hemoragik dan stroke hemoragik. Variabel independen meliputi usia, diabetes melitus, dan hipertrigliseridemia. Jumlah sampel penelitian sebanyak 100 sampel. Hasil penelitian menunjukkan 59 persen pasien berada pada kelompok dewasa dan 41 persen pada kelompok lansia. Diabetes melitus ditemukan pada 51 persen pasien dan hipertrigliseridemia pada 43 persen pasien. Analisis bivariat menunjukkan hubungan signifikan antara usia, diabetes melitus, dan hipertrigliseridemia dengan tipe stroke. Analisis multivariat menunjukkan usia berpengaruh signifikan terhadap tipe stroke, sedangkan diabetes melitus dan hipertrigliseridemia meningkatkan risiko terjadinya tipe stroke. Adapun faktor risiko yang berpengaruh terhadap tipe stroke adalah usia, diabetes melitus, dan hipertrigliseridemia. Kata Kunci: Usia, Diabetes Melitus, Hipertrigliseridemia, Tipe Stroke.
Hubungan Stres Kerja, Beban Kerja, dan Dukungan Sosial Terhadap Kesejahteraan Psikologis Caregiver Formal Pasien Kanker di RSUD Provinsi NTB Ni Made Yurita Parawangsa; Made Agus Suanjaya; I Putu Dedy Arjita; Nisia Putri Rinayu
MAHESA : Malahayati Health Student Journal Vol 6, No 9 (2026): Volume 6 Nomor 9 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i9.24732

Abstract

ABSTRACT Formal caregivers of cancer patients play an important role in the caregiving process; however, high job demands may adversely affect their psychological well-being. Psychological well-being among formal caregivers is influenced by work-related stress, workload, and social support. This study aimed to examine the relationships between work stress, workload, and social support and the psychological well-being of formal caregivers of cancer patients at RSUD Province of West Nusa Tenggara in 2025. This study employed a quantitative analytical observational design with a cross-sectional approach. Total sampling was used, involving 53 respondents. Data were analyzed using the Spearman Rank correlation test and ordinal logistic regression. Univariate analysis showed that most respondents were female (77.4%), in early adulthood (50.9%), and had a long working tenure (10 years) (39.6%). The majority of respondents experienced moderate work stress (62.3%), heavy workload (66.0%), and moderate social support (56.6%), with psychological well-being categorized as moderate (49.1%) and high (50.9%). Bivariate analysis revealed a significant relationship between work stress and psychological well-being (p = 0.003) as well as between social support and psychological well-being (p = 0.026), while workload was not significantly associated with psychological well-being (p = 0.924). Multivariate analysis indicated that work stress had the strongest tendency of association with psychological well-being after controlling for other variables; however, the findings should be interpreted with caution due to limitations in model fit and the cross-sectional study design. In conclusion, work stress and social support were associated with the psychological well-being of formal caregivers of cancer patients, whereas workload was not significantly related. Keywords: Psychological Well-Being, Formal Caregiver, Work Stress, Workload, Social Support.  ABSTRAK Caregiver formal pasien kanker memiliki peran penting dalam proses perawatan, namun tuntutan pekerjaan yang tinggi berpotensi memengaruhi kesejahteraan psikologis. Kesejahteraan psikologis caregiver formal dipengaruhi oleh stres kerja, beban kerja, dan dukungan sosial. Tujuan penelitian ini adalah mengetahui hubungan stres kerja, beban kerja, dan dukungan sosial dengan kesejahteraan psikologis caregiver formal pasien kanker di RSUD Provinsi NTB tahun 2025. Penelitian ini merupakan penelitian kuantitatif analitik observasional dengan desain cross-sectional. Teknik pengambilan sampel menggunakan total sampling dengan jumlah sampel sebanyak 53 responden. Data dianalisis menggunakan uji Korelasi Spearman Rank dan regresi logistik ordinal. Hasil analisis univariat menunjukkan sebagian besar responden berjenis kelamin perempuan (77,4%), berada pada usia dewasa awal (50,9%), dan memiliki masa kerja lama (39,6%). Mayoritas responden mengalami stres kerja sedang (62,3%), beban kerja berat (66,0%), dan dukungan sosial sedang (56,6%), dengan kesejahteraan psikologis berada pada kategori sedang (49,1%) dan tinggi (50,9%). Hasil analisis bivariat menunjukkan terdapat hubungan signifikan antara stres kerja dan kesejahteraan psikologis (p = 0,003) serta antara dukungan sosial dan kesejahteraan psikologis (p = 0,026), sedangkan beban kerja tidak menunjukkan hubungan yang signifikan (p = 0,924). Analisis multivariat menunjukkan bahwa stres kerja memiliki kecenderungan hubungan paling kuat dengan kesejahteraan psikologis setelah dikontrol bersama variabel lain, namun interpretasi hasil perlu dilakukan secara hati-hati mengingat keterbatasan kesesuaian model dan desain penelitian. Kesimpulan penelitian ini adalah stres kerja dan dukungan sosial berhubungan dengan kesejahteraan psikologis caregiver formal pasien kanker, sedangkan beban kerja tidak menunjukkan hubungan yang bermakna. Kata Kunci: Kesejahteraan Psikologis, Caregiver Formal, Stres Kerja, Beban Kerja, Dukungan Sosial.