Article Per Year (5 Year)
p-Index From 2021 - 2026
2.986
P-Index
This Author published in this journals
All Journal Majalah Kedokteran Gigi Indonesia ODONTO Dental Journal Padjadjaran Journal of Dentistry Jurnal Medika Malahayati Padjadjaran Journal of Dental Researchers and Students Abdi Dosen : Jurnal Pengabdian Pada Masyarakat Jurnal Material Kedokteran Gigi Conservative Dentistry Journal Journal of Innovation Research and Knowledge SENTRI: Jurnal Riset Ilmiah Odonto dental journal Jurnal Pengabdian Masyarakat Bangsa JPMP Jurnal Pengabdian Masyarakat
Diana Soesilo, Diana
Unknown Affiliation
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

Published : 18 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search
Journal : Conservative Dentistry Journal

 1 
Antimicrobial activity of calcium hydroxide, calcium oxide, and mineral trioxide aggregate paste against α-Hemolytic Streptococcus Darmadi, Eveline Yulia; Soesilo, Diana
Conservative Dentistry Journal Vol. 14 No. 1 (2024): January-June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v14i1.2024.24-28

Abstract

Background: The bacteria mostly found in the root canals are aerobic and facultative anaerobic bacteria, such as α-Hemolytic Streptococcus. Calcium hydroxide has alkaline characteristics with pH of 12.5, and antimicrobial properties. Calcium oxide is hydrophilic and has a smaller molecular weight than calcium hydroxide. Mineral trioxide aggregate (MTA) has alkaline properties, good biocompatibility, stimulates healing and inhibits bacterial growth. Purpose: The purpose of this study was to examine the differences of antimicrobial activity between calcium hydroxide, calcium oxide, and mineral trioxide aggregate (MTA), also to find which of these materials has the highest antimicrobial activity. Methods: The design of this study was a post-test only control group design. The study subjects were divided into 4 groups. K (-) was control group without any treatment, P1 was treated with calcium hydroxide, P2 was treated with calcium oxide, and P3 was treated with MTA. Each group consisted of 7 samples. The α-Hemolytic Streptococcus were spread on Mueller Hinton agar. Antimicrobial test was using diffusion method and diameter of inhibition zones were measured with caliper. Results: Average inhibitory zone of each sample was P1 (30.9643 mm ± 0,7431), P2 (35,2357 mm ± 0,7099), P3 (28,6 mm ± 1,5532). Tukey HSD test showed significances results between samples P1 and P2 (p=0,001), P1 and P3 (p=0,002), P2 and P3 (p=0,001). Conclusion: The highest antimicrobial activity against α-Hemolytic Streptococcus was calcium oxide followed by calcium hydroxide and MTA.
Effectiveness of Nipah leaf extract (Nypa fruticans) against Streptococcus mutans biofilm as cavity cleanser Handriutomo, Yosef Kevin; Soesilo, Diana; Aprilia, Aprilia; Parisihni, Kristanti; Rayhan, Rafialdi; Cahyani, Febriastuti
Conservative Dentistry Journal Vol. 15 No. 1 (2025): January-June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v15i1.2025.23-26

Abstract

Background: Streptococcus mutans is the primary bacterium responsible for dental caries, found in the biofilm on the tooth surface, known as dental plaque. Before restorative treatment or cavity care for carious teeth, a cavity cleanser is necessary to remove residual bacteria that could cause secondary caries or restoration failure. Nipah leaf extract contains phenol, flavonoids, saponins, and steroids, which can destroy bacteria by denaturing proteins and damaging bacterial cell membranes. Objective: To determine the antibiofilm activity of Nipah leaf extract against Streptococcus mutans biofilm. Materials and Methods: The materials used were Nypa fruticans leaf extract prepared using the maceration method at concentrations of 1%, 5%, 10%, and 15%, with chlorhexidine gluconate as the positive control and distilled water as the negative control. Bacteria cultured in BHI media were inoculated into a 96-well flat-bottomed plastic tissue culture plate and incubated for 24 hours at 37°C. Optical Density (OD) was measured using an ELISA reader. Results: KM: 0.039; K (-): 0.887; K (+): 0.085; P1: 0.727; P2: 0.463; P3: 0.347; P4: 0.169. The Mann-Whitney test results showed significant differences between K (+) and P1 (0.000), K (+) and P2 (0.000), K (+) and P3 (0.000), K (+) and P4 (0.005), P1 and P2 (0.000), P1 and P3 (0.000), and P1 and P4 (0.000). The results were significant as p < 0.05. Conclusion: Nipah leaf extract (Nypa fruticans) can inhibit the biofilm formation of Streptococcus mutans bacteria.
The inhibitory activity of Avicennia marina leaf extract on Enterococcus faecalis as a root canal irrigation material Prabanita, Amellindha Salsabilah; Soesilo, Diana; Sularsih; Dwi Andriani; Kuntjoro, Mefina; Prasetyo, Eric Priyo
Conservative Dentistry Journal Vol. 15 No. 2 (2025): July-December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v15i2.2025.57-61

Abstract

Background: Enterococcus faecalis is considered the most common cause of root canal failure and persistent infection. The standard irrigation solution is 5.25% NaOCl which has drawbacks, such as causing inflammation in the periapical area. New antibacterial agents from natural materials with similar antibacterial properties to chemicals have been developed. Avicennia marina contains flavonoids, saponins, tannins, and avicequinone, which can inhibit bacterial metabolism. Objective: to determine the effect of Avicennia marina leaf extract with various concentrations on the antibacterial inhibitory power of Enterococcus faecalis as a root canal irrigation material. Materials and Methods: The samples were divided into six groups: K+ (5.25% NaOCl), K- (distilled water), P1 (7.5%), P2 (12.5%), P3 (17.5%), and P4 (22.5%). The leaves of Avicennia marina were extracted using ethanol maceration with a rotary evaporator to obtain a concentrated extract, which was then diluted with distilled water to the desired concentrations. The antibacterial effect was tested using the disk diffusion method by applying 0.01 ml of each test sample to sterile paper disks with a sterile micropipette. Results: Inhibition zones were observed as follows: K+ (21.67 mm), P1 (0 mm), P2 (10.50 mm), P3 (13.50 mm), and P4 (14.50 mm). Mann Whitney tests showed significant differences (p < 0.05) between K+ and P1, P2, P3 and P4, as well as between P3 and P4. Conclusion: Avicennia marina leaf extract had antibacterial effects against Enterococcus faecalis at concentrations of 12.5%, 17.5%, and 22.5%.
Co-Authors Acep Rohendi Agnita Cevanti, Twi Akwan, Yulie Emilda Anindya Pinasti, Restika Aprilia Aprilia, Aprilia Ariestania, Vivin Arini, Virginnita Whindi Arya Brahmanta, Arya Aulia Dwi Maharani Cahyo, Benny Dwi Christabel, Phebe Fedora Damaiyanti, Dian Widya Dasrun Hidayat Dian Mulawarmanti, Dian Diyah N.K., Chaterina Dwi Andriani Dwi Maharani, Aulia Eddy Hermanto Eric Priyo Prasetyo Erliany Syaodih Eveline Yulia Darmadi Fani Pangabdian, Fani Febriastuti Cahyani Febrina, Agni Fitria Rahmitasari Fitricia, Ria Handriutomo, Yosef Kevin Hanum, Faizah Hayati, Kurnia Hendro, Onge Victoria Hollanda, Ghita Hadi Icha Artyas Annariswati Iman, Dimas Ira Amelia Juniar, Eriza Khoironi, Emy Kristanti Parisihni Lestari, IGAM Oka Linda Rochyani, Linda Listya Paramita, Annisa Mefina Kuntjoro Megantara, Rizko Wira Artha Nurrahim, Firman Paramita, Annisa Listya Paramita, Ayulistya Pinansti, Restika Anindya Prabanita, Amellindha Salsabilah Pranoto, Amelia Elizabeth Puspita, Sinta Putri Paramita Raharjo, Pambudi Ramadhi, Cakrawartyha Rayhan, Rafialdi Riski, Mardiyanti Riski, Mardiyanto Rizal, Mohammad Basroni Rossy, Meralda Sarianoferni Sularsih Sularsih, S Syahdinda, Meralda Rossy Syamsulina Revianti Twi Agnita Cevanti Velisia, Jessica Victoria, Onge Wahyu Setiani, Muhammad Wanda Rahma Syanti Widaningsih Widaningsih, Widaningsih Widyasri Prananingrum Wira, Rizko Yongki Hadinata Wijaya Yoyada, Novendy Yufita Fitriani Yuniarta, Alfian