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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Syntax Literate: Jurnal Ilmiah Indonesia JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Media Dermato-Venereologica Indonesiana Journal of General Procedural Dermatology and Venereology Indonesia Bali Dermatology Venereology and Aesthetic Journal
Afif Nurul Hidayati, Afif Nurul
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Humanities Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Faktor Pencetus Dan Faktor Risiko Rekurensi Herpes Simpleks Genitalis Dan Orolabialis Donis, Ghefira Sonia; Hidayati, Afif Nurul; Machin, Abdullah; Alinda , Medhi Denisa
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i11.62487

Abstract

Herpes simplex is a sexually transmitted disease caused by the herpes simplex virus (VHS). Patients who have been infected with herpes simplex are susceptible to recurrence. So this research explains the trigger factors and recurrence of herpes simplex virus genitalis and orobialis. This research method is a retrospective study using medical records of herpes simplex patients. The research sample is inpatients diagnosed with herpes simplex according to the inclusion and exclusion criteria using total sampling technique. The number of samples for this study was 30 patients with herpes simplex virus. The independent variables of this research are UV rays, psychological stress, immunosuppression, and physical trauma. The dependent variable of this study is the trigger factor and recurrence of herpes simplex virus. Data analysis used the sperm rho statistical test to determine the correlation between variables. The statistical test results did not show a p value for exposure to UV light because there were no respondents who had a trigger factor in the form of UV light, p=0.000 and a correlation coefficient of 0.910 for psychological stress, p=0.001 and a correlation coefficient of 0.658 for immunosuppression, there was no p value because there was no there were respondents who had factors that trigger menstruation, p= 0.000 and a correlation coefficient of 0.979 for physical trauma against factors that trigger herpes simplex virus, there was no p value for cold weather trigger factors because no respondents experienced cold weather trigger factors. There is p = 0.053 and coefficient correlation 0.595 on the recurrence factor of UV exposure, p = 0.006 and coefficient correlation 0.769 on psychological stress, p = 0.022 and coefficient correlation 0.792 on immunosuppression, p = 0.009 and coefficient correlation 0.739 on menstruation, p = 0.000 and The correlation coefficient was 0.911 for physical trauma, and there was no p value for the cold weather factor because no respondents experienced cold weather recurrence factors. The conclusion is that there is no relationship between UV rays and menstruation as a trigger factor for herpes simplex, there is a relationship between psychological stress, immunosuppression and physical trauma to the trigger factors, there is a relationship between exposure to UV rays, psychological stress, immunosuppression, physical trauma to the recurrence factors of herpes simplex virus
Clinical Characteristics and Microbiological Profile of Oral Candidiasis among HIV-Positive Patients in Indonesia: A Literature Review Prameshvari, Putu Lovina Indra; Permana, Putu Bagus Dharma; Hidayati, Afif Nurul; Murtiastutik, Dwi; Arfijanto, Muhammad Vitanata
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 3 (2025): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikkk.V37.3.2025.209-217

Abstract

Background: As the country with the highest identified active cases of HIV/AIDS across Southeast Asia, Indonesia faces a massive challenge in providing adequate antiretroviral therapy (ART) coverage to prevent disease progression and mortality.  Oral candidiasis (OC) is the most frequently identified oral manifestation of HIV infection and represents the degree of immunosuppression, treatment failure, and prognosis among people living with HIV/AIDS. Demographic characteristics, clinical types, and causative pathogens of OC vary between different geographical and socioeconomic settings. Hence, the role of oral candidiasis is crucial in developing effective strategies to address the HIV-related burden in Indonesia. Review: This literature review evaluated 11 descriptive studies conducted across eight major cities in Indonesia, comprising 764 HIV-positive patients diagnosed with OC. Most affected individuals were male and exhibited advanced immunosuppression, with the majority presenting CD4+ counts below 200 cells/mm³. Six clinical variants of OC were identified, with pseudomembranous candidiasis being the predominant form, followed by angular cheilitis, erythematous candidiasis, hyperplastic candidiasis, and sporadic cases of atrophic candidiasis and denture stomatitis. Microbiological findings showed Candida albicans as the leading etiologic species; however, non-albicans Candida (NAC)—particularly C. krusei, C. glabrata, and C. tropicalis—demonstrated notable prevalence, including mixed colonization with C. albicans. The rise of NAC species highlights concerns regarding antifungal resistance in the ART era. Conclusion: Oral candidiasis serves as an important clinical finding among patients living with HIV/AIDS, and its appropriate management is necessary not only to prevent further complications but also to mitigate the recent development of antifungal resistance.
Co-Authors Agung, Jeffrey Alinda , Medhi Denisa Anggraen, Sylvia Anggraeni, Sylvia Arifin Saiboo, Alvian Astindari Astindari Astindari, Astindari Bagus Haryo Kusumaputra Bagus Haryo Kusumaputra, Bagus Haryo Basuki, Mudjiani Bintanjoyo, Lunardi Budi Utomo Budiono Budiono Cita Rosita Sigit Prakoeswa Damayanti Damayanti Damayanti Devi, Aprilin Krista Diah Mira Indramaya Donis, Ghefira Sonia Dwi Murtiastutik Effendy, Isaac Eliza, Frizka Esti Hendradi Evy Ervianti Evy Ervianty, Evy Fadila, Arisia Fajrin, Farah Meriana Harningtyas, Citra Dwi Hartanto, Felix Indah Purnamasari Indramaya, Diah INDROPO AGUSNI Irmadita Citrashanty Irmadita Citrashanty, Irmadita Izzatul Fithriyah Jusuf Barakbah, Jusuf Kinanti, Hapsari Linda Astari, Linda Luthfidyaningrum, Hamidah M. Yulianto Listiawan Machin, Abdullah Machin, Abdulloh Made Putri Hendaria Mappamasing, Hasnikmah Martodiharjo, Sunarko Maylita Sari Maylita Sari, Maylita Medhi Denisa Alinda, Medhi Denisa Medisika, Dhea Menul Ayu Umborowati, Menul Ayu Muhammad Vitanata Arfijanto, Muhammad Vitanata Nadiva, Shafa Karin Nugroho, Wisnu Triadi Nurasrifah, Dewi Pepy Dwi Endraswari, Pepy Dwi Permana, Putu Bagus Dharma Prameshvari, Putu Lovina Indra Pramitha, Riezky Januar Rahmadewi Rahmadewi Rahmadewi Regitta Indira Agusni Reza, Novianti Rizky Saut Sahat Pohan Sawitri Sawitri Sawitri SEPTIANA SEPTIANA Tengku Riza Zarzani N Trisniartami Setyaningrum Widodo J. Pudjirahardjo Widyantari, Septiana Willy Sandhika Yuindartanto, Andre Yuri Widia, Yuri Yusuf Wibisono