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All Journal Pharmasipha Indonesian Journal of Global Health research Medfarm: Jurnal Farmasi dan Kesehatan Jurnal Kesehatan Tambusai Jurnal Ilmiah Wahana Pendidikan Jurnal Buana Farma Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Proceeding ISETH (International Summit on Science, Technology, and Humanity) Prosiding University Research Colloquium JURNAL JAMU KUSUMA Duta Pharma Journal Proceeding of International Conference Health, Science And Technology (ICOHETECH) Cerdika: Jurnal Ilmiah Indonesia Prosiding Seminar Informasi Kesehatan Nasional International Journal of Health, Engineering and Technology Journal of Educational Innovation and Public Health Jurnal Ilmiah Kesehatan JURNAL FARMASI DAN KESEHATAN INDONESIA The International Science of Health Journal Jurnal Riset Ilmu Kesehatan Umum dan Farmasi CERATA Usadha Journal of Pharmacy Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan International Journal of Health and Medicine Bhamada: Jurnal Ilmu dan Teknologi Kesehatan (E-Journal) Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Danang Raharjo
Pogram Studi Farmasi, Fakultas Kesehatan, Universitas Duta Bangsa, Surakarta
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : Jurnal Buana Farma

 1 
STUDI IN VITRO ANTIKOLESTEROL DAN FLAVONOID TOTAL DARI EKSTRAK BAWANG PUTIH TUNGGAL (Allium sativum L) Nafiah, Azidatun; Raharjo, Danang; Ardiyantoro, Bagas
Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i3.1504

Abstract

Hypercholesterolemia is one of the main factors that increase the risk of heart and blood vessel disease, which can cause atherosclerosis and disorders in fat metabolism. Single garlic is known to contain bioactive compounds such as flavonoids that play a role in reducing cholesterol. This study aims to assess the total flavonoids and anticholesterol activity in vitro of ethanol extract of single garlic (Allium sativum L.). The extraction process was carried out using the maceration method with 96% ethanol as the solvent. Total flavonoids were measured using UV-Vis spectrophotometry with quercetin as the standard, while anticholesterol activity was tested using the Lieberman-Burchard method in vitro. The findings of this study indicate that the sample extract contains secondary metabolites such as flavonoids, alkaloids, saponins, and tannins. Single garlic shows effective flavonoid content in lowering lipid levels. The anticholesterol test shows that this extract can reduce cholesterol levels with a significant IC₅₀ value. The conclusion of this study is that single garlic has the potential as an alternative way to lower cholesterol.
PENGARUH KONSENTRASI ETANOL TERHADAP TOTAL FENOLIK DAN FLAVONOID SERTA AKTIVITAS ANTIOKSIDAN DARI DAUN KUNYIT (Curcuma longa L.) DENGAN METODE ABTS Nurcahyani, Dona Agustin; Raharjo, Danang; Apriliawan, Hidayah
Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i3.1520

Abstract

Turmeric's leaves possess the greatest antioxidant potential. Therefore, further utilization of flavonoid and phenolic compounds is necessary as antioxidants and to enhance their bioactivity as a medicine. This study aimed to determine the effect of ethanol concentration on total phenolic content using the Folin-Ciocalteau analysis method while total flavonoid content using the AlCl₃ analysis method and antioxidant activity of turmeric leaves using the ABTS method, The research design used was experimental research. The results obtained were ethanol concentrations of 50%, 70% and 96%, The results showed that 70% ethanol extract had the highest phenolic content with an average of (63.77 ± 0.40 mg GAE / g), and 70% ethanol extract had the highest flavonoid content with an average of (22.88 ± 0.5 mg QE / g). However, the strongest antioxidant activity was shown by 96% ethanol extract with an IC₅₀ value of (46.36 ± 1.15 ppm (<50 ppm). Thus, turmeric leaf extract with 96% ethanol solvent had the strongest antioxidant activity, while 70% ethanol produced the highest phenolic and flavonoid levels.
Co-Authors Addawiyyah, Muniroh Adiyantoro, Bagas Aini, Riszki Nur Aminnulloh, Muhammad Aminnulloh, Muhhamad Aminulloh, Muhammad Anita Dwi Septiarini Anita Dwi Septiarini S Anna Fitriawati Apriliawan, Hidayah apriliyanti, laela intan Bagas Ardiyantoro Bangkit Riska P Bangkit Riska Permata Bangkit Riska Permata Chyang, Pang Jyh Desy Ayu Irma Permatasari Diana Nurrah Ashari Dwi Bagus Pambudi Dwi Bagus Pambudi Dwi Budi Santoso Dwi Nurul Khotimah Dwi S, Anita Eny Wijayanti Fadilla, Fitri Hansa Fatimah Azzahro Febriyani, Rima Fevi Indri Oktaviani Fitriwati, Anna Gusmao, Nandito Manuel Ximenes Haryoto, H Hidayat, Allif Nur Ilham Zikri kristian saputra, samuel Kusumaningtyas Siwi Artini Listyani, Tiara Ajeng Lisyani, Tiara Ajeng Luthfia Dhiyaul Amalia Luthfiyanti, Niken Lydia Fitriana M. Adam Firdausi Muhamad Farid Nurohman Krisnadi Musniati, Musniati Nafiah, Azidatun Niken Luthfiyanti Nuniek Nizmah Fajriyah Nurcahyani, Dona Agustin NURUL HIDAYAH Oktafia Nur Fatimah Pambudi, Dwi Bagus Permata, Bangkit Riska Permatasari, Desy Ayu Irma Pratama, Kharisma Jayak Rafidah Hanifah Raharjo, Oktavia Wijaya Rahmat Hidayat Ramadhani, Diza Aulia Rusmiati Rusmiati Salsabila Khoerunniyssa Sania, Sania Septian Maulid Wicahyo Setyaningrum, Fidya Siska Wardani, Tatiana Siti Fatimah Siti Fatimah Siwi Artini, Kusumaningtyas Sya'bania, Muti' Tiara Ajeng L Tiara Ajeng L. Vinkasari, Elriza Wardani , Tatiana Siska Wardani, Tatiana Siska Wulandari, Nia Isa Yuliya Rahma