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All Journal HAYATI Journal of Biosciences Perspektif : Review Penelitian Tanaman Industri Indonesian Journal of Pharmaceutical Science and Technology Elkawnie Majalah Obat Tradisional Abditani : Jurnal Pengabdian Masyarakat Jurnal Ilmiah Farmasi Farmasyifa Perspektif, Review Penelitian Tanaman Industri Jurnal Abdimas Kartika Wijayakusuma Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian Riset Informasi Kesehatan AGRIC kawanad Jurnal Medika: Medika Kartika : Jurnal Ilmiah Farmasi Medical Sains : Jurnal Ilmiah Kefarmasian Pharmacon: Jurnal Farmasi Indonesia Jurnal Farmasi Galenika
Akhirul Kahfi Syam
Fakultas Farmasi Universitas Jenderal Achmad Yani
Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Control & Systems Engineering Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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ANTIOXIDANT ACTIVITY OF VARIOUS EXTRACTS OF JARAK TINTIR (Jatropha multifida L.) STEM, PHENOLIC AND FLAVONOID CONTENT Syam, Akhirul Kahfi; Windyaswari, Ari Sri; Ratnawati, Julia
JURNAL FARMASI GALENIKA Vol 7 No 3 (2020): Jurnal Farmasi Galenika Vol 7 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v7i3.182

Abstract

Background: Jarak tintir (Jatropha multifida L.) was identified as one of family Euphorbiaceae and used by Indonesian people as traditional medicine. This study aimed to measure IC50 of inhibition DPPH as free radicals and make statistical analysis of flavonoid and phenolic content and correlation with their IC50 of free radicals. Methods: Hot continuous extraction was done with Soxhlet apparatus using various polarity solvents (n-hexane, ethyl acetate, and methanol). Results: Methanol extract had the lowest IC50 32.26 ± 0.37 µg/mL of DPPH inhibition activity. Ethyl acetate extract had highest phenolic and highest flavonoid content with 35.21 ± 1.50 mg TAE/g extract and 49.41 ± 1.65 mg QE/g extract. Conclusion: Flavonoid and phenolic content in extracts had linier correlation with their IC50 of inhibition free radicals.
Tantangan Industri Farmasi Indonesia di Era Pandemik COVID-19 Windyaswari, Ari Sri; Hermanto, Faizal; Vikasari, Suci Nar; Riyanti, Soraya; Syam, Akhirul Kahfi; Febrinella, Catellya
Jurnal Abdimas Kartika Wijayakusuma Vol 1 No 2 (2020): Jurnal Abdimas Kartika Wijayakusuma
Publisher : LPPM Universitas Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (522.939 KB) | DOI: 10.26874/jakw.v1i2.74

Abstract

Abstrak: Situasi pandemik COVID-19 di Indonesia mempengaruhi beberapa sektor penting, diantaranya adalah sektor kesehatan. Farmasi sebagai salah satu garda penting di bidang kesehatan mempunyai tugas fungsi pokok untuk menyediakan obat yang aman, berkhasiat dan berkualitas. Industri farmasi merupakan bagian terdepan yang memiliki peranan penting tersebut sekaligus merupakan bagian terdepan yang terkena dampak dari situasi pandemik COVID-19. Tekanan untuk penemuan vaksin/obat baru sebagai antivirus COVID19 hingga produksi vitamin dan produk nutrisi lain sebagai upaya preventif untuk melindungi masyarakat Indonesia dari peningkatan penularan virus COVID-19 di Indonesia menghadapi berbagai kendala. Pembatasan Sosial Berskala Besar (PSBB), kegiatan karantina serta isolasi merupakan salah satu kendala di dalam bidang produksi. Disisi lain, permintaan akan produk obat meningkat tajam. Apoteker industri dan apoteker komunitas bekerja sama untuk memastikan ketersediaan dan efek terapi obat dapat digunakan oleh masyarakat Indonesia. Tujuan dilaksanakannya webinar ini adalah untuk mengubah paradigma permasalahan menjadi suatu tantangan yang harus diselesaikan oleh sejawat apoteker di seluruh Indonesia. Metode webinar dilaksanakan melalui penyampaian materi dan diskusi panel dari platform ZOOM dan youtube. Hasil post test yang dilaksanakan terhadap 1.700 peserta secara garis besar menunjukkan pemahaman dan kepedulian masyarakat dalam mengatasi berbagai permasalahan di bidang farmasi industry Indonesia. Kata kunci: Apoteker, Industri Farmasi, COVID-19.
Effect of Different Solvents on Toxicity and Secondary Metabolites of Mangkokan Leaves (Polyscias scutellaria (Burm.f.) Fosberg) by Brine Shrimp Lethality Test (BSLT) Method Syam, Akhirul Kahfi; Sabilia, Syahra Asfi; Riyanti, Soraya
Pharmacon: Jurnal Farmasi Indonesia Vol. 21 No. 1 (2024)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i1.3185

Abstract

Mangkokan (Polyscias scutellaria (Burm.f.) Fosberg) is one of the plants belonging to the Araliaceae family. Empirically, mangkokan plants, especially the leaves, are used by the community as traditionalmedicine. Mangkokan leaves need to be developed into a source of natural materials such as biopesticides, biolarvicide, and anticancer agents because they have toxic compounds. Secondary metabolite compounds of mangkokan leaves consist of flavonoids, saponins, monoterpenes-sesquiterpenes, and steroids. This study aims to determine the toxicity of n-hexane, ethyl acetate, and ethanol extracts of mangkokan leaves using the Brine Shrimp Lethality Test (BSLT) method. Mangkokan leaves were extracted by graded maceration method using n-hexane, ethyl acetate, and 96% ethanol solvents. All three extracts were tested BSLT on Artemia salina larva test animals. The toxicity level is expressed by the LC50 value obtained from the probit analysis. The LC50 value of n-hexane, ethyl acetate, and ethanol extracts was 146.724 μg/mL, respectively; 66.029 μg/mL; and 92.007 μg/mL. The results showed that all three extracts were toxic.
Sosialisasi Penanganan Pasca Panen Bahan Baku Rempah Obat Tradisional Faramayuda, Fahrauk; Riyanti, Soraya; Syam, Akhirul Kahfi; Windyaswari, Ari Sri; Karlina, Yeni; Limbong, Remare Halomoan; Fitrichia, Anggita Esa Putri; Pertiwi, Ananda Tunjung; Aprilia, Trialisa; Mutya, Ema; Dewi, Renti Mutiara; Pratiwi, Dwi Ayu; Septiani, Usi; Amedea, Esanda Zulfi; Wulandari, Yesi; Fitriani, Adinda; Dwigantina, Ami Soega
Kawanad : Jurnal Pengabdian kepada Masyarakat Vol. 1 No. 2 (2022): October
Publisher : Yayasan Kawanad

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56347/kjpkm.v1i2.52

Abstract

Community service activities carried out by students of Universitas Jenderal Achmad Yani were carried out on August 29, 2022, taking place in a medicinal plant garden, Faculty of Pharmacy, Universitas Jenderal Achmad Yani which was attended by UMKM Spice Nusantara Bandung participants. The socialization carried out was the presentation and delivery of post-harvest processing materials (wet sorting, washing, drying, and dry sorting) and the standardization of traditional raw materials. Conventional medicine is a form of treatment efforts in the community to support health which is currently being recommended by the government. Communities can use the toga as an economical and efficient measure to maintain body immunity because the community can obtain and use the toga quickly and simply to maintain family health. The postharvest process greatly determines the existence of active compounds that are efficacious for treatment. Incorrect postharvest management can change, reduce, or destroy the active substance of a plant into a substance that has no therapeutic effect and can even endanger health. The results of the participant's level of understanding were carried out post-test with the results of what is the purpose of post-harvest processing (100%), the sequence of post-harvest processing (80%), what is the general drying temperature (100%), a medicinal plant has good quality and efficacy then we need to know (80%), and what is the function of the washing process (90%) with the conclusion that socialization activities can significantly increase the knowledge of participants from MSMEs regarding planting, post-harvest processing, and the properties of medicinal plants significantly.
Co-Authors Adinda Fitriani Adinugraha, Irham M. Akbar, Tzazkia Febriyana Amedea, Esanda Zulfi Ami Soega Dwigantina Ananda Tunjung Pertiwi Anggita Esa Putri Fitrichia Anna Choirunnisa Anna Choirunnisa, Anna Aprilia, Trialisa Ari Sri Windyaswari Ari Sri Windyaswari Ari Sri Windyaswari Ari Sri Windyaswari, Ari Sri Azhar, Farah Salsabilla Saidah Dadan Suryasaputra Desti Hermawati Dewi, Renti Mutiara Dewilestari, Meyra Pratami Dwi Ayu Pratiwi Dwigantina, Ami Soega Elfahmi Elfahmi, Elfahmi Ema Mutya Esanda Zulfi Amedea Fahrauk Faramayuda Fahrauk Faramayuda, Fahrauk Faizal Hermanto Farah Salsabilla Saidah Azhar Faramayudha, Fahrauk Farhan Febrinella, Catellya Fitriani, Adinda Fitrichia, Anggita Esa Putri Florence Meliawaty Handayani, Dewi Ratih Hermawati, Desti Hestiary Ratih Ismail, Nursafira Khairunnisa Jaka Permana Julia Ratnawati Julia Ratnawati Julia Ratnawati Julia Ratnawati, Julia Juliastuti, Henny Khaerunnisa, Rahmadaniah Komar Ruslan Wirasutisna Lahagu, Helga Nitulo Berliana Limbong, Remare Halomoan Mardiana, Grace Selly Meyra Pratami Dewilestari Muhamad Insanu Muhammad Irwan Mutya, Ema Nandi Agustian Pertiwi, Ananda Tunjung Pratiwi, Dwi Ayu Purwoko, Agus Puspita Satriyani Permatasari Surasa Putri, Dhiffa Namira Alifia Rahaju, Asih Rakhmat, Iis Inayati Ramdhani, Amalia Kusuma Remare Halomoan Limbong Renata Ananda Marthasedana Renti Mutiara Dewi Sabilia, Syahra Asfi Sabirin, Indah Puti R. Septiani, Usi Septiani, Vina Sheila Nur Hasanah Sheila Nur Hasanah Sigid Pamungkas Wicaksono Soraya Riyanti Soraya Riyanti Soraya Riyanti Soraya Riyanti, Soraya Sri Restu Andriyani Suci Nar Vikasari, Suci Nar Sufyan Zainul Arifin Sukrasno Suntana, Mutiara Sukma Surasa, Puspita Satriyani Permatasari SURYANI Totik Sri Mariani Trialisa Aprilia Usi Septiani Vina Septiani Wulan Anggraeni Wulandari, Yesi Yeni Karlina Yeni Karlina Yeni Karlina, Yeni Yesi Wulandari Yuslianti, Euis Reni