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All Journal Biocelebes Acta Pharmaceutica Indonesia Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) As-syifaa Jurnal Farmasi Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Akademika Kimia JFL : Jurnal Farmasi Lampung PREPOTIF : Jurnal Kesehatan Masyarakat Journal of Nursing and Public Health (JNPH) Jurnal Health Sains Lumbung Inovasi: Jurnal Pengabdian Kepada Masyarakat Jurnal Buana Farma Jurnal Abdimas Bina Bangsa JIPI (Jurnal IPA dan Pembelajaran IPA) Jurnal Medika: Medika Jurnal Pengabdian Farmasi dan Sains Jurnal Akademika Kimia
Ririen Hardani
Jurusan Farmasi , Fakultas Matematika Dan Ilmu Pengetahuan Alam , Universitas Tadulako, Palu, Sulawesi Tengah
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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HUBUNGAN KOMPONEN EQ-5D-3L DALAM PENILAIAN KUALITAS HIDUP PENERIMA VAKSIN SINOVAC® DI PELAYANAN KESEHATAN KOTA PALU Rumi, Amelia; Arief, Thendi Abdul; Hardani, Ririen
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 8 No. 1 (2024): APRIL 2024
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v8i1.25329

Abstract

Penerima vaksin Sinovac® di pelayanan kesehatan menjadi kelompok terdepan yang memiliki risiko tertinggi terjadinya penularan, sehingga menjadi prioritas utama dalam penerimaan vaksin. Selain itu, mempunyai peran penting dalam pemberian vaksin kepada masyarakat sehingga sangat penting untuk menilai kualitas hidup setelah divaksinasi. Penelitian bertujuan untuk menilai hubungan EQ-5D-3L terhadap kualitas hidup dan komponen yang paling kuat hubungannya serta hubungan karakteristik demografi terhadap komponen EQ-5D-3L. Penelitian ini menggunakan metode deskriptif dengan pendekatan cross sectional dengan jumlah responden 365 orang. Teknik pengambilan sampel dalam penelitian ini menggunakan data primer secara purposive sampling, pengambilan data menggunakan kuesioner EQ-5D-3L melalui google form dan hardcopy. Analisis data menggunakan korelasi Spearman, Chi-square dan Exact-fisher. Hasil korelasi Spearman menunjukkan nilai p-value (0,000) yang menunjukkan hubungan secara signifikan berupa hasil komponen kemampuan berjalan (-0,404), perawatan diri (-0,481), kegiatan yang biasa dilakukan (-0,566), rasa nyeri (-0,932), dan rasa depresi/cemas (sedih) (-0,631). Disimpulkan bahwa terdapat hubungan yang bermakna terhadap kualitas hidup. Sedangkan komponen EQ-5D-3L yang paling kuat hubungannya terhadap kualitas hidup adalah rasa nyeri. Hasil uji Chi-square dan Exact-fisher dapat disimpulkan bahwa terdapat hubungan yang bermakna antara komponen EQ-5D-3L terhadap karakteristik demografi (usia, waktu terakhir penyuntikan, status perkawinan, dan menyusui). Sedangkan, tidak ada hubungan yang bermakna terhadap jenis kelamin dan pekerjaan.
Pelatihan Pengelolaan dan Pemusnahan Limbah Obat Rusak dan Kadaluarsa di Desa Kotapulu Kabupaten Sigi Tandah, Muhamad Rinaldhi; Diana, Khusnul; Adisaputra, Arya Dibyo; Hardani, Ririen
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 2 No. 2 (2024): April 2024
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2024.v2.i2.17096

Abstract

The widespread circulation of illegal drugs poses a serious threat to society as it can have negative impacts on health. In 2019, BPOM Palu confiscated illegal drugs and cosmetics from various areas in Central Sulawesi. A law enforcement operation in Sigi Regency on September 23, 2020, together with the Central Sulawesi Regional Police, successfully seized Class G prescription drugs, traditional medicines, and illegal cosmetics (BPOM Palu, 2022). The main cause of illegal drug circulation is the improper reuse of household drug waste, exploited by irresponsible parties. The use of illegal drugs, which may consist of counterfeit, damaged, or expired items, can endanger health and even lives. One crucial step to prevent this is by managing drug waste properly. Since 2019, BPOM has been conducting awareness campaigns such as "Beware of Illegal Drugs, Dispose of Drug Waste Properly" to educate the public on proper drug disposal (BPOM, 2019). Many people still don't understand the correct way to manage and dispose of expired drugs. Most of them throw these drugs into the trash, potentially fueling illegal drug reuse by irresponsible parties. Training and awareness efforts, such as those conducted in Kotapulu Village, Dolo District, Sigi Regency, are highly relevant. With better knowledge of proper drug management and disposal, it is hoped that communities can independently address drug waste issues, ultimately reducing the circulation of illegal drugs in the region. These activities are crucial for educating the public about the dangers of illegal drugs and the importance of proper drug waste management. The goal is to help reduce the circulation of illegal drugs, especially in Central Sulawesi, thereby safeguarding the overall health and safety of the community.
Determination of Tanin Extract of Belimbing Wuluh Leaves (Averrhoa Bilimbi L.) by Uv-Vis Spectroscopy Methods Hardani, Ririen; Hardani, Muhammad F.; Hamzah, Baharuddin; Tamala, Sindy T.
Jurnal Akademika Kimia Vol. 14 No. 3 (2025)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24775185.2025.v14.i3.pp138-143

Abstract

Wuluh star fruit plant (Averrhoa bilimbi L.) was a traditional medicinal plant that was rarely utilized as a natural medicine and contained many secondary metabolite compounds, one of which was tannin. This study aimed to determine the type of tannin and the amount of tannin content in belimbing wuluh leaves. Wuluh star fruit leaf powder was extracted by the maceration method using 96 % ethanol solvent, and then the filtrate was concentrated by rotary evaporator. Identification of tannin types in the extract was performed using CH3COOH 10 %, (Pb(CH3COO)2) 10 %, HCl, FeCl3, and KBr. For analysis of tannin content, Folin-Ciocalteau reagent and 15 % Na2CO3 solution were added, and then analyzed using UV-Vis spectrophotometry at a wavelength of 765 nm. The results of the identification of tannin types showed that belimbing wuluh leaves included condensed tannins, and the results of the analysis showed that the tannin content was 7.282 mg/g extract.
The Effectiveness of Bougainvillea (Bougainvillea spectabilis willd) Extract on Reducing Blood Glucose in Hypercholesterolaemia White Rats Muhammad Fakhrul Hardani; Baharuddin Hamzah; Ririen Hardani; Magfirah; Sitti Rahmawati; Purnama Ningsih
Jurnal Penelitian Pendidikan IPA Vol 11 No 1 (2025): January
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i1.9762

Abstract

Bougainvillea leaves are often used by the public as a treatment by drinking boiled water, but their use as a blood sugar-lowering agent is not supported by scientific data. The purpose of this study was to determine the effect of reducing blood glucose levels and to determine the dose of extract that is effective in in white rats. The plant's herbal extract was prepared using the reflux method with 90% ethanol solvent. This study uses a laboratory experimental method to compare blood glucose levels in white rats before and after administration of herb extract at doses of 100, 200, and 300 mg/kg BW orally using high-fat feed induction and streptozotocin. Blood glucose levels were measured using a glucometer, and mice were declared positive for diabetes with fasting blood sugar levels above 126 mg/dL. The number of test animals used in this study was 30 mice, divided into 6 groups. A randomized block design was used as the research design. The study's findings revealed that administering Bougainville spectabilis willd herb extract at doses of 100, 200, and 300 mg/kg BW can reduce blood glucose in test animals with an effective dose of 200 mg/kg BW
ANALISIS EFEKTIVITAS BIAYA OMEPRAZOLE DAN RANITIDIN PADA PASIEN DISPEPSIA DI INSTALASI RAWAT INAP RSUD UNDATA PALU Hardani, Ririen; Ambianti, Nurul; Safarudin, Rudi; Syafaah , Tri Atainah
Jurnal Buana Farma Vol 6 No 1 (2026): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v6i1.1582

Abstract

The prevalence rate of dyspepsia continues to increase, with cases of recurrence occurring in patients not only adding to the physical and psychological burden of patients, but can also pose an economic burden on both patients and the health system. This study aims to determine the cost of therapy in dyspepsia patients based on the ACER value. This study is a descriptive study, data obtained from medical records and financial data of dyspepsia patients at Undata Hospital, Palu. Data analysis was done descriptively using Microsoft excel and statistically using Kruskal wallis test, Chi-square and independent T-test. The results of the study based on the Kruskal wallis test obtained a p-value of 0.002 which indicates that there is a significant effect of secondary diagnosis on direct medical costs of dyspepsia patients, and the cost effectiveness of therapy based on the ACER value of omeprazole of Rp 35,965 and the ACER value of ranitidine of Rp 28,965. The conclusion of this study is that ranitidine is more cost effective than omeprazole in dyspeptic patients at the inpatient installation of RSUD Undata Palu.
KUALITAS HIDUP PASIEN DIABETES MELLITUS TIPE 2 GERIATRI DI POLIKLINIK GERIATRI RUMAH SAKIT UMUM DAERAH ANUTAPURA PALU RIRIEN HARDANI; KHILDAH KHAERATI; ANDI BUNGA SINGKARRU; NURUL AMBIATI
Journal of Nursing and Public Health Vol 13 No 2 (2025)
Publisher : UNIVED Press, Universitas Dehasen Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37676/jnph.v13i2.10051

Abstract

Pendahuluan: Prevalensi diabetes melitus (DM) di Indonesia menunjukkan trend yang terus meningkat dari tahun ke tahun. Laporan Riskesdas 2018 menunjukkan prevalensi DM cenderung semakin tinggi seiring dengan bertambahnya usia dan mencapai puncaknya pada kelompok usia 55 – 74 tahun. Pada pasien geriatri, DM berdampak signifikan terhadap kualitas hidup. Penelitian ini bertujuan untuk mengevaluasi kualitas hidup pasien DM geriatri yang melakukan pengobatan rawat jalan di poliklinik geriatri RSUD Anutapura Kota Palu, serta hubungannya dengan faktor demografis pasien (jenis kelamin, IMT, pekerjaan dan tingkat pendidikan). Metode: Penelitian ini bersifat kuantitatif dengan desain observasional prospektif di mana sampel ditentukan melalui teknik purposive sampling. Data yang dikumpulkan meliputi karakteristik demografis, jenis pengobatan, manifestasi klinis serta persepsi kualitas hidup pasien melalui kuesioner SF-36. Analisis dilakukan secara univariat, bivariat dan uji korelasi Perason Hasil dan Pembahasan: Kualitas hidup pasien relatif baik pada domain keterbatasan emosional, kesehatan mental, fungsi sosial dan nyeri tubuh, tetapi buruk pada domain fungsi fisik, keterbatasan fisik, vitalitas dan kesehatan umum. Tidak terdapat korelasi bermakna antara kualitas hidup dengan faktor demografis pasien (p > 0,05). Kesimpulan: Kualitas hidup pasien DM geriatri cenderung rendah pada aspek fisik namun masih menunjukkan hasil yang baik pada aspek mental dan emosional. Faktor demografis tidak berkontribusi signfikan sehingga faktor lain yang bersifat klinis, psikososial dan sprilitual perlu dipertimbangkan dalam penelitan maupun intervensi selanjutnya memahami faktor yang memengaruhi kualitas hidup pasien DM geriatri secara lebih holistik.
Co-Authors Adelisa Putri Adisaputra, Arya Dibyo Afriani Kusumawati afriani kusumawati, afriani Alfia, Dhara Alwiyah Mukaddas Amelia Rumi Amelia Rumi Amelia Rumi amelia rumi, amelia ANDI BUNGA SINGKARRU Arief, Thendi Abdul AURELIA, DIVA Baharuddin Hamzah Baharuddin Hamzah Baharuddin Hamzah Chindy Bestari Rataba Devyayu Prabaningsih Dwi Lestari Handayani Erwan Sastrawan Fandi, Indra Dwi Farida Abd. Rasul Firdawati amir parumpu Firdawati Amir Parumpu Hamdani, Silviana Handoko Putro Hardani, Muhammad F. Hardani, Muhammad Fakhrul I Gusti Ngurah Antaryama I Kadek Adi Krisna Ingrid Faustine Jusriadi KHILDAH KHAERATI Khildah Khaerati Khusnul Diana M. Ilham M. Sutrisno M. Zain Gifary Magfirah Masyita, Andi Atirah Mohammad Amin Mohammad Amin Muhamad Rinaldhi Tandah Muhammad Amiruddin Muhammad Fakhrul Hardani Muhammad Fakhrul Hardani Nabila Khatliyah Ni Made Susilawati Nurlina Ibrahim Nurul Ambianti NURUL AMBIATI Oviana Kristiono Parumpu, Firdawati Purnama Ningsih Purwanto, Ananda Putri Recky Patala Safarudin, Rudi Siti alimah syafiqah Sitti Rahmawati Sri Rizqi Muthmainnah Sugeng Santoso Sukmawati, Sukmawati Syafaah , Tri Atainah Tamala, Sindy T. Teguh Hilmansyah Tri Randy Saputra Yuliet Yuliet Yusriadi Yusriadi