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PUASA PADA KEBUNTINGAN TRIMESTER 1, 2 DAN 3 RELATIF AMAN DILIHAT PADA INDEKS APOPTOSIS SEL NEURON OTAK RATTUS NORVEGICUS BARU LAHIR Wati, Yunita Kholilaili Saras; Joewono, Hermanto Tri; Miftahussurur, Muhammad
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 9, No 2 (2021): EDITION JULY 2021
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33366/jc.v9i2.1388

Abstract

Fasting in pregnancy that can increase neural network activity in the brain region and produce BDNF secretions that seek survival pathways will produce pro survival / anti apoptosis in cerebral neuron cells and the cerebellum. The aim of this study to analyze the effect of fasting during pregnancy on the index of apoptosis of cerebral neuron cells and the cerebellum of the newly born Rattus norvegicus. This research was using Experimental laboratory studies that were correct with the post test study design were only the control group design using experimental animals Rattus norvegicus at the Pathology Laboratory of the Faculty of Medicine, Airlangga University Surabaya which were collected into 3 research groups (1st, 2nd, and 3rd trimesters) and 1 control group . Each group consisted of 6 Rattus norvegicus mothers. The brain dissection of the newborn Rattus norvegicus child was taken and the apoptotic index was calculated using the Immunohistochemical Tunnel method. and discuss with the Immunoreactive Score (IRS). The results of the Kruskal wallis analysis were expressed as the Cerebrum apoptosis index in all four groups (p 0.05). Most apoptosis in the cerebrum was in the first trimester (3.9) and lowest in the second trimester (1.5). The results of the cerebellar apoptosis index analysis by the Kruskall wallis test proved that the most cerebellar apoptosis in the first trimester (4.87) and the lowest in the second trimester (1.33). Conclusion there is no difference between the 1,2 th trimester and 3 in the control of the cerebrum and cerebellum
Faktor-faktor yang Mempengaruhi Pengambilan Keputusan dalam Melakukan Vaksinasi HPV pada Mahasiswa Kesehatan: Literature Review Watari, Rekno; Handayani, Samsriyaningsih; Miftahussurur, Muhammad
Jurnal Ilmiah Universitas Batanghari Jambi Vol 24, No 1 (2024): Februari
Publisher : Universitas Batanghari Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33087/jiubj.v24i1.3866

Abstract

The research aims to analyze the factors that influence the administration of HPV vaccination to health students. The research method used is a literature review. The literature search uses data for the last 5 years from electronic databases such as PubMed, Science Direct, and Google Scholar. After fulfilling the inclusion and exclusion criteria, six articles were collected and discussed in the literature review. Literature results N=106, Pubmed N=53, ScienceDirect N=12, Google Scholar N=41. Six papers can be reviewed and fulfilled based on the inclusion criteria. Based on the results of the journal review, the research concludes that several things influenced health students in carrying out the HPV vaccination, knowledge about cervical cancer and HPV vaccination, attitudes and support for getting vaccinated, and exposure to social media
Bridging Faith and Innovation: A Review of Social Innovation and Social Value Creation in Faith-Based Philanthropy Organizations Dinar Apriyanto; FENDY SUHARIADI; Muhammad Miftahussurur
Jurnal Ilmu Multidisiplin Vol. 4 No. 4 (2025): Jurnal Ilmu Multidisplin (Oktober - November 2025)
Publisher : Green Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38035/jim.v4i4.1417

Abstract

This review addresses the challenge Faith-Based Philanthropy Organizations (FBPOs) face in integrating social innovation while demonstrating social value. These organizations must balance their unique religious identity with increasing secular demands for measurable impact. This study's objectives are to map how FBPOs implement social innovation, identify the mechanisms linking faith identity to value creation, and propose an integrated conceptual model. A scoping review methodology was employed, utilizing database searches (including Scopus and Web of Science) followed by a qualitative thematic synthesis. The results indicate that FBPOs engage in all four typologies of social innovation (product, process, position, paradigm), distinctly leveraging "religious capital" (trust, volunteer networks, religious funds) as a key input. This process generates multi-dimensional value, including material and crucial non-material (spiritual/communal) outcomes. The findings conclude that FBPOs operate as hybrid organizations managing competing logics, and a conceptual "Faith-Innovation-Value" (F-I-V) model is proposed, highlighting a critical gap in the measurement of non-material value.
CTC or CEA: Choosing Reliable Markers for Metastatic Colorectal Cancer Miftahussurur, Prof. Dr. dr. Muhammad
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 26, No 3 (2025): VOLUME 26, NUMBER 3, December, 2025
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2632025201-203

Abstract

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Capsule Endoscopy as a Diagnostic Tool for Inflammatory Bowel Disease in a Patient with Multiple Myeloma Rizkiawan, Naufali; Mahmudah, Isna; Miftahussurur, Muhammad
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 26, No 3 (2025): VOLUME 26, NUMBER 3, December, 2025
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2632025280-286

Abstract

Capsule endoscopy is an important tool for minimally invasive evaluation of the small bowel, allowing improved diagnostic yield with low complication rates relative to traditional modalities. Here, we present the first case of inflammatory bowel disease (IBD) diagnosed by a capsule endoscopy in Surabaya. There was a case of a patient who suffered chronic diarrhea for four months. When the patient experienced persistent diarrhea, generalized weakness was then reported as a symptom. The patient then received a conventional endoscopy and was planned for a colonoscopy. However, the endoscopy was canceled due to the patient's respiratory distress. The patient underwent capsule endoscopy, where hyperemia and erosion from the small intestine to the colon were found. The diagnosis of IBD was established and the patient was given sulfasalazine 500 mg every 24 hours. In order to image the small intestine endoscopically, capsule endoscopy remains to be the preferred method. This case serves as an example of the advantages of capsule endoscopy, especially in terms of the diagnosis of inflammatory bowel disease.
Saffron and folic acid mitigate hepatic structural damage in IUGR rats via modulation of oxidative stress markers: A histological and molecular study Nur Aini Hasan; Viskasari Pintoko Kalanjati; Iswandi Erwin; Lucky Prasetiowati; Joni Susanto; Muhammad Miftahussurur
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 8 No 2 (2026): In Progress
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v8i2.7919

Abstract

One of the major causes of Intrauterine Growth Restriction (IUGR) in Indonesia is maternal malnutrition during pregnancy. Folic Acid has long been the primary supplement administered to women from preconception through pregnancy. Additionally, several studies have demonstrated that Saffron possesses anti-inflammatory and hepatoprotective properties. However, the effects of Saffron on liver tissue in IUGR rat models remain underexplored. This study aimed to investigate the effects of Saffron administration compared to Folic Acid on birth weight, hepatic tumor necrosis factor-alpha (TNF-α) expression, and liver histopathology in IUGR rats. Forty female and eight male rats were mated. Upon confirmation of pregnancy, the dams were randomly assigned to four groups: normal control (K1), receiving a standard diet throughout pregnancy (19-21 days) and lactation (21 days); IUGR control (K2), subjected to 50% dietary restriction (DR); IUGR + Saffron group (K3), receiving DR plus Saffron extract at 15.68 mg/kg body weight; and IUGR + Folic Acid group (K4), receiving DR plus Folic Acid at 1.5 mg/kg body weight. After 21 days of lactation, the offspring were euthanized, and liver tissues were collected for histological and immunohistochemical analyses. Pups' birth weights, hepatic TNF-α expression (immunohistochemistry), and histological damage (NAS score) were assessed. Folic acid showed superior effects in increasing birth weight, reducing TNF-α, and improving liver histology compared to saffron. These findings suggest folic acid as a potent hepatoprotective agent in IUGR conditions.
Co-Authors AA Hubur Adi Pranoto Adinda Juwita Syakila Elizafanti Agoes Soegianto Agus Sulistyono Alfaray, Ricky I. Alpha Fardah Athiyyah Alshawsh, Mohammed A. Amie Vidyani Ana, Devi Andino Maseleno Annisa Zahra Mufida Astri Dewayani Aswin, R Haryanto Ayu Citra Gestari Bernadetta Jonan Brian Eka Rahman Budi Prasetyo Budi Widodo Chabib Fachry Albab Dewi, Selva R. Diah Rizki Rahma Dini Dianbudiyanto, Wahid Dinar Apriyanto Dita Mega Utami Djazuly Chalidyanto Djoni Susanto Dominicus Husada Dwiki Noni Armyta Dwiyanti Puspitasari, Dwiyanti Eka Mishbahatul Mar'ah Has Endyka Erye Frety Fauzia, Kartika A. Fauziah Diayu Retnaningtyas Fendy Suhariadi Gatut Hardianto, Gatut Gilda Hartecia Hadisuwarno, Wiharjo Hajjarianti, Permata Hamzah Hamzah Hartecia, Gilda Hasan Maulahela Heasty Oktaricha HERAWATI, LILIK Hermanto Tri Joewono Herry Purbayu Hunowu, Ramdan I'tishom, Reny Indra Alfaray, Ricky Ishomatul Faizah Isna Mahmudah Isna Mahmudah Iswan A Nusi Iswan Abbas Nusi Iswandi Erwin Izzatul Fithriyah Jonan, Bernadetta Juniastuti Juniastuti Karnaji Karnaji Kartika Afrida Fauzia Lionardy Yodianto Lucky Prasetiowati Mahmudah, Isna Maria Inge Lusida Martono Tri Utomo MISBAKHUL MUNIR Mohammad Anam Al-Ari Nadia Sherli Syafira Natasya Ariesta Selyardi Putri Naufali Rizkiawan Nihayati, Hanik Endang Nur Aini Hasan Nurhayati, Fitasari Nidia NUrina Fitriani, NUrina Nurullia Hanum Hilfida Pangestu Adi Pathak, Yashwant Poernomo Boedi Setiawan Purwo Sri Rejek Rejeki, Purwo Sri Riani Widia Parantika Rizkiawan, Naufali Samsriyaningsih Handayani Savitri, Camilia Metadea Aji Soelistijo, Soebagijo Adi Sugiyatmi, Tri A. Sulistiawati Sulistiawati Susanti Susanti Tanaya, Willa M. Thamrin, Husin Titong Sugiharto Titong Sugihartono Tri Purwanti Ucik Nurul Hidayati Ulfa Kholili Ummi Maimunah Usman Hadi Vasa Adi Wisnu Wardana Viskasari P. Kalanjati Wahyul Anis Watari, Rekno Wati, Yunita Kholilaili Saras Wessels, Firda I. Widjiati Widjiati, Widjiati Widyaleksono, Trisnadi Willy Sandhika Woro Setia Ningtyas Yoshio Yamaoka Yoshio Yamaoka Yoshio Yamaoka, Yoshio Yudith Annisa Ayu Rezkitha Yudith Annisa Ayu Rezkitha, Yudith Annisa Ayu Zagita, Lauditta Chavia