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All Journal Jurnal Teknologi Industri Pertanian BIOLINK (Jurnal Biologi Lingkungan, Industri, Kesehatan) JURNAL EKSAKTA PENDIDIKAN (JEP) BIOEDUSAINS: Jurnal Pendidikan Biologi dan Sains JURNAL PERSPEKTIF PENDIDIKAN Dharma Raflesia : Jurnal Ilmiah Pengembangan dan Penerapan IPTEKS Jurnal Inovasi Pengabdian Masyarakat Pendidikan DIKSAINS : Jurnal Ilmiah Pendidikan Sains Andromeda: Jurnal Pengabdian Masyarakat Rafflesia Journal of Multidisciplinary Research
Arsela Eko Listiono
Universitas Bengkulu
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Education Engineering Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Mathematics Physics Social Sciences Other

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Pemberian Jus Buah (Etlingera hemisphaerica) terhadap Pemulihan Eritrosit dan Leukosit Akibat Perlakuan Merkuri Klorida (HgCl2) pada Mencit (Mus musculus) Fatimah Azzahrah; Aceng Ruyani; Deni Parlindungan; Arsela Eko Listiono; Afrizal Mayub
BIOEDUSAINS:Jurnal Pendidikan Biologi dan Sains Vol. 8 No. 5 (2025): Bioedusains: Jurnal Pendidikan Biologi dan Sains
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31539/7ef7hb33

Abstract

This study aims to determine the effect of Etlingera hemisphaerica (honje) fruit juice on the recovery of erythrocyte and leukocyte counts in mice (Mus musculus) exposed to mercuric chloride (HgCl₂). The method used was an experimental design using male mice as test animals, divided into three groups: K1 (control), K2 (honje juice 0.3 mL/20 g BW for 3 days), and K3 (HgCl₂ 5 mg/kg BW + honje juice 0.3 mL/20 g BW for 3 days). The observed parameters were the number of erythrocytes and leukocytes before and after treatment. The results showed that honje juice administration increased the erythrocyte count in group K2, while in group K3, erythrocyte recovery was affected by mercury exposure, making the honje juice less effective, although the values remained within the normal range compared to the control group. In leukocyte count, group K2 showed a stabilizing effect, whereas group K3 experienced an increase due to HgCl₂ exposure. In conclusion, Etlingera hemisphaerica fruit juice has potential as a phytotherapy agent to repair hematological damage caused by heavy metal toxicity, although its effectiveness is influenced by the metabolic condition of the mice and the high concentration of mercury. Keywords: Etlingera hemisphaerica, Erythrocytes, Leukocytes, Mice, Mercuric Chloride
Pengaruh Pemberian Nanopartikel Kitosan - Ekstrak Batang J. multifida L terhadap Jumlah Eritrosit M. musculus yang Teriinfeksi P. berghei Listiono, Arsela Eko; Firdaus, M. Lutfi; Sundaryono, Agus
BIOEDUSAINS:Jurnal Pendidikan Biologi dan Sains Vol. 8 No. 6 (2025): BIOEDUSAINS:Jurnal Pendidikan Biologi dan Sains
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31539/be7vbx11

Abstract

This study aimed to determine the effect of administering chitosan nanoparticles loaded with Jatropha multifida L. stem extract on the erythrocyte count of Mus musculus infected with Plasmodium berghei as well as their characterization results. The method used was the preparation of chitosan nanoparticles loaded with J. multifida L. stem extract using the ionic gelation method. Characterization results using Particle Size Analysis (PSA) showed that the chitosan nanoparticles loaded with J. multifida L. stem extract had an average particle size of 567.12 nm with a polydispersity index (PDI) value of 0.11, while characterization using X-ray diffraction (XRD) showed the highest peak at a 2θ angle of 28.68°. The results indicated differences in the effects of varying concentrations of chitosan nanoparticles loaded with J. multifida L. stem extract on erythrocyte counts. The conclusion of this study is that the most effective dose of chitosan nanoparticles loaded with J. multifida L. stem extract was 0.028 g/kg body weight, followed by the administration of crude J. multifida L. stem extract at the same dose.   Keywords: Erythrocytes, Jatropha multifida L., Chitosan, Nanoparticles, Particle Size Analysis, Plasmodium berghei, X-ray Diffraction
Co-Authors ACENG RUYANI Afrizal Mayub Ariefa Primair Yani ASTUTI, ANNISA PUJI BHAKTI KARYADI Budiyanto Budiyanto Defianti, Aprina Deni Parlindungan Dilisti, Dilisti Elsi Adelia Fitri Elvinawati Fatimah Azzahrah Febriansyah, Muhammad Firdaus, Mochamad Lutfi Henny Johan I Nyoman Candra Kurniani, Riska M. Lutfi Firdaus, M. Lutfi Mayub, Afrizal Nabila, Anggun T. Nurhamidah Nursaadah, Euis Romawina, Demi Susanti Susanti Syeptiani, Silvia Tukiman Tukiman Umaya Umaya, Umaya Yusni Arni