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All Journal Health Science Journal of Indonesia Jurnal Kebijakan Kesehatan Indonesia Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Jurnal Kesehatan Andalas Berkala Kedokteran MNJ (Malang Neurology Journal) The Indonesian Biomedical Journal Jurnal Ilmiah Kedokteran Wijaya Kusuma Jurnal Penelitian Kesehatan Suara Forikes Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Jurnal Pengabdian Pada Masyarakat Jurnal Kesehatan Komunitas BIOEDUSCIENCE Jurnal Kedokteran Anatomica (Anatomica Medical Journal) Window of Health : Jurnal Kesehatan Media Keperawatan Indonesia IKRA-ITH ABDIMAS Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education INTEGRITAS : Jurnal Pengabdian Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal) Journal of Applied Data Sciences SEGARA : Jurnal Pengabdian Kepada Masyarakat Journal of Research in Pharmacy and Pharmaceutical Sciences Jurnal Kedokteran Meditek The Health Researchers Journal Journal of Religion and Public Health Medicosphere
Makkiyah, Feda Anisah
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Journal : BIOEDUSCIENCE

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Antibacterial Activity of Graptophyllum pictum (L.) Griff Extract using Variations of Ultrasonic Frequency against Escherichia coli Oktavia, Sabina; Bahar , Meiskha; Wahyuningsih, Sri; Zulfa , Fajriati; Makkiyah, Feda Anisah
BIOEDUSCIENCE Vol 8 No 2 (2024): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/14168

Abstract

Background: Escherichia coli is a Gram-negative bacteria and is the main suspect for urinary tract infections and gastroenteritis. The cases of antibiotic resistance against E. coli continue to increase due to public non-compliance with taking antibiotics. Purple leaf (Graptophyllum pictum (L.) Griff) is a plant that grows widely in Indonesia and is generally used as a herbal medicine. This plant contains alkaloids, flavonoids, tannins, and steroids, which can inhibit bacterial growth. This content is obtained through an extraction process. This study aimed to determine the difference in effectiveness of purple leaves extracted using the Ultrasound-Assisted Extraction method at a frequency of 30 kHz, 40 kHz, and 50 kHz against the growth of E. coli. Methods: This research is purely experimental and was carried out in vitro. The antibacterial activity test used the suitable diffusion method, and then the diameter of the inhibition zone was measured. This research was analyzed using the Kruskal-Wallis and Mann-Whitney tests, which resulted in significant differences between treatment groups. Results: The average diameter of the inhibition zone produced at frequencies of 30 kHz, 40 kHz, and 50 kHz is 3,40 mm, 6,22mm, and 4,37mm. Conclusions: The results of this research show that the most optimal frequency is 40 kHz; this frequency can form cavitation in purple leaf cells, thereby producing phytochemical substances that can damage the cell structure of E. coli.
Co-Authors Abd. Rasyid Syamsuri Ahmad Aulia Ahmad Taufik Aisyah, Ammara Alifah Safira Amperatmoko Alya Roza Lisanti Anisah Anisah Antoni, Darius Apriningsih, Apriningsih Apriningsih Arfiyanti Arfiyanti Arfiyanti, Arfiyanti Aritonang, Hosianna Stephany Ayu Devania Dipta Gayatri, Gusti Ayu Magdalena Natalia Situmeang Basuki Supartono Bintang Bayu Aryandi Buana, Gherriandi Raja Budiman, Anisa Novita Dian Pertiwi Dian Pertiwi Digna, Audrey Alvura Erna Harfiani Faustine, Gracella Fitriana Fitriana Goenarjo, Roman Gracella Faustine Heni Pujiastuti Heristyorini, Ayodya Herkan, Muhamad Thariq Imam Prabowo, Imam Juliana, Dian Kamaludin, Fahmi Marlina Dewiastuti Marlina Dewiastuti, Marlina Masiran, Ruziana` Meiskha Bahar Melly Kristanti Muhammad Ferrel Privansyah Cader Cader Muhammad Reihan Arianda Nabila Aulia Ainaya Nafira, Amodya Dahayu Napitupulu, Partogi Natanel, Handro Steve Nugrahana, Raisa Yunika Nurfitri Bustamam Nurhadi Ibrahim Nurrahmah, Rahma Nida Nurrizka, Rahmah Huda Oktafiani, Devi Oktavia, Sabina Pasiak, Taufiq Fredrik Prita Maya Savitri Rachmawati, Alfira Rahma Hida Nurrizka Rahmah Hida Nurrizka Rahmah Huda Nurrizka Rizkyta, Bunga Mentari Rosadi, Andrea Salsabila Sabita, Rifqi Safira, Lisa Salim Harris, Salim Sembiring, Rinawati Setyaningsih, Yuni Shelly Nobel Shofiy, Alifya Rayyani Sihotang, Theodora Caroline Subeno, Setia Syahrin, Rosita Alfi Taufik Jamaan Taufiq Fredrik Pasiak Tiwuk Susantiningsih Wahyudi, Dhyani Paramita Widayani Wahyuningtyas Yani, Sri Yuni Setyaningsih Yuri Nurdiantami Zulfa , Fajriati