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Journal : MEDISAINS

The effectiveness of topical gel formulation extract Centella asiatica and Curcuma domestica to fading striae gravidarum Oktavia, Eva Zuli; Hadisaputro, Suharyo; Rahayu, Sri
MEDISAINS Vol 21, No 3 (2023)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v21i3.19130

Abstract

Background: The incidence of striae gravidarum in Indonesia is 95%, and 79.7% are primigravida. Striae gravidarum is not a direct physical health risk but is associated with body image and decreased self-confidence. Curcuma domestica contains curcumin and vitamin C, which can stimulate the synthesis of type IV collagen. In contrast, the Centella asiatica plant contains triterpenoids and saponins, which can stimulate the synthesis of type I collagen, which helps regenerate skin cells and improve skin elasticity. However, it is necessary to see the effectiveness of the two herbs, Centella asiatica and Curcuma domestica, in fading striae gravidarum. Purpose: To prove the effectiveness of topical gel formulation extract Centella asiatica and Curcuma domestica for fading of striae gravidarum.Methods: This is a quasi-experimental study with a pretest-posttest control group design. The sample consisted of 32 primigravida pregnant women divided into two groups: the intervention group was given a combination of Curcuma domestica and Centella asiatica gel at a dose of 5 mg twice a day for 14 days, and the control group was given a mineral oil gel at a quantity of 5 mg twice a day for 14 days—measurement of striae gravidarum using Davey score. The statistical test used the Friedman and Wilcoxon test.Results: The average fading of striae gravidarum in the intervention group was more significant than in the control group, 11.44±4.131 to 4±3.033 vs.12.19±5.788 to 8.56±4.320 treatment on the 14th day. The analysis results showed that the topical gel formulation of Centella asiatica and Curcuma domestica was more effective in fading striae gravidarum than the placebo gel (p<0.001).Conclusion: Administering topical gel containing 12% Centella asiatica extract and a 10% Curcuma domestica dose of 5 mg twice a day for 14 days affected the fading of striae gravidarum.
Co-Authors Achjar, Komang Ayu Henny Andisetyana Putri, Hanifa Ari Suwondo Arum Budiyati Astari, Ni Kadek Yunita Ari Aulia Choirunnisa Ayu Dharmawati, Gst Agung Choiroel, M. Dewa Ayu Mirah Jayantini Dewi, Ida Ayu Dhian Permana Diksi Laksmita Dewi Dina Hanifa Ditha Rizky Oktavianti Djamaluddin Ramlan, Djamaluddin Donny Kristanto Mulyantoro Donny Kristanto Mulyantoro Erna Widyastuti Fajrin, Rafika Faridah, Salsabila Nur Fera, Fitria Candra Gama, Ketut Gusti Ayu Marhaeni Hadi Hadi Hadi Hadi Hanifa Putri Hesti Kurniasih I Gusti Agung Ayu Novya Dewi Ima Nurcahyanti Putri Isnu Kurnia Nugrahaeni Kadek Ditha Ari Sevtiani Karmika, Ni Nyoman Kalih Kiki Yusika Krisnayanti , Komang Ayu Kuswanto Kuswanto Lailatul Hidayah Librawati, Susi Listyaning Eko Martanti Listyaning Eko, Martanti Made Dita Argya Prabaswari Made Widhi Gunapria Darmapatni Mahendra, Ida Bagus Made Putra Mardiyana, Shinta Lia Nana Marsum Marsum Melyana Nurul Widyawati Mutiara Ayu Muthiatulsalimah Ngadiyono Ngadiyono Ni Ketut Somoyani Ni Komang Erny Astiti Ni Komang Yuni Rahyani Ni Nyoman Budiani, Ni Nyoman Ni Nyoman Suindri Ni Wayan Suarnit Ni Wayan Suarniti Nia Dwi Yuliati Noor Pramono Noor Pramono Novita Novita Nur Anisa Octaviani, Dhita Aulia Oktavia, Eva Zuli Putri, Hanifa Putri, Noviyati Rahardjo Putu Ayu Oktarini Retno Kusuma Dewi Rica Anjayani Rizkie Aulia Amini Rizky Amelia Runjati Saraswati, Putu Rosita Setya Prihatin Setyo, Prihatin Sri Endang Windiarti Sri Lestari, Agus Sri Purwati Sri Sumarni Sri Sumarni Sri Wahyuni Sri Wahyuni Suharyo Hadisaputro Suparmi Suparmi Supriyadi Supriyadi Tecky Afifah Santi Amartha Titi Suherni Triana Sri Hardjanti Umaroh Umaroh Umaroh Umaroh Umaroh Umaroh Utami, Fetty Satu Ryan Wahyuni, Sri Warih Handayani Tri Murti Wiardani, Komang Yudrika, Filza Yuni Nor Aini