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All Journal Journal of Food and Pharmaceutical Science Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) ILKOM Jurnal Ilmiah BERDAYA: Jurnal Pendidikan dan Pengabdian Kepada Masyarakat Borneo Journal of Medical Laboratory Technology Movere Journal Ta'dib: Jurnal Ilmiah Pendidikan dan Peradaban Islam Amsir Management Journal Jurnal Bakti Untuk Negeri GMPI Conference Series Herbal Medicine Journal Journal of Food and Pharmaceutical Sciences Balance: Jurnal Ekonomi
Ma’ruf, Muhammad
Unknown Affiliation
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences

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Dampak Variasi Genetik terhadap Respon Terapi dan Potensi Hemolisis Anemia dari Penggunaan Primakuin melalui Pendekatan Farmakogenetika Sianu, Rahman Sumani; Ghifari, Annisa Abdi; Ma’ruf, Muhammad; Nur Jannah, Eka Yuni; Lestari, Putri Ayu
Herbal Medicine Journal Vol 9 No 1 (2026): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58996/hmj.v9i1.219

Abstract

Primaquine is essential for radical cure of Plasmodium vivax malaria but poses hemolysis risk in G6PD-deficient individuals and shows variable therapeutic responses. Genetic polymorphisms in drug-metabolizing enzymes and transporters contribute to these inter-individual variations. To investigate genetic variants in G6PD, SLCO2B1, and MAOA genes that influence primaquine safety and efficacy, and to assess their clinical implications for personalized antimalarial therapy. Method the database used in this study is PhramGKB. Genetic polymorphisms in four candidate genes were analyzed for associations with hemolysis, anemia, therapeutic efficacy, and malaria recurrence. Statistical analyses determined the strength and significance of genotype-phenotype associations. Result G6PD variants rs1050828 and rs1050829 showed strong associations with hemolysis (p<0.01) and anemia (p=0.001). SLCO2B1 variant rs12422149 was associated with reduced chloroquine-primaquine efficacy (p=0.01). MAOA variant rs6323 increased malaria recurrence risk (p=0.03). Conclusion multiple genetic variants significantly impact primaquine safety and efficacy. These findings support pharmacogenetic-guided personalized antimalarial therapy to optimize outcomes and minimize adverse events, contributing to malaria elimination efforts.
Sentiment analysis of customer satisfaction levels on smartphone products using Ensemble Learning Ma’ruf, Muhammad; Kuncoro, Adam Prayogo; Subarkah, Pungkas; Nida, Faridatun
ILKOM Jurnal Ilmiah Vol 14, No 3 (2022)
Publisher : Prodi Teknik Informatika FIK Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/ilkom.v14i3.1377.339-347

Abstract

Increasingly sophisticated technological developments create new ways for people to conduct trading business. An example of this technology application is the use of e-commerce. However, there are conditions where the seller cannot measure the level of satisfaction and identify problems experienced by his customers if it is only based on the rating as the case in smartphones transactions. Therefore, a solution is needed to create a system that can filter negative and positive comments. This study offers a solution to address this issue by using machine learning employing the K-Nearest Neighbors, SVM, and Naive Bayes algorithms with hyperparameters from previous studies. This study applied the ensemble learning method with the Voting Classifier technique, which is an algorithm to combine several algorithms that have been made. From the test results, the highest accuracy was obtained by SVM with an accuracy value of 91.18% while the ensemble learning method obtained an accuracy value of 89.22%. The difference in the accuracy of training and testing for SVM and ensemble learning method is 7.1% and 4% respectively. These results indicate that the ensemble learning method can help improve the performance of sentiment analysis algorithms for comments on smartphone products.
Pendampingan Digitalisasi Pemasaran UMKM melalui Pemanfaatan E-Commerce di Desa Bumi Nabung Utara, Lampung Tengah Maulana, Ronal Jusuphan; Ma’ruf, Muhammad; Salsabila, Suci; Sari, Sukma Kumala; Aprilia, Venny; Saputri, Vivi May; Elviana, Windi; Andini, Yulita Dian; Saputri, Olyfiah Nazzwa; Putra, Alfiansyah Imanda
BERDAYA: Jurnal Pendidikan dan Pengabdian Kepada Masyarakat Vol 8 No 2 (2026)
Publisher : LPMP Imperium

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36407/berdaya.v8i2.1817

Abstract

The rapid development of digital technology has created opportunities for Micro, Small, and Medium Enterprises (MSMEs) to expand their market reach; however, low digital literacy and the continued dominance of conventional marketing remain major challenges, particularly in Bumi Nabung Utara Village. This Community Service Program (PKM) aims to enhance digital literacy and marketing capabilities of MSME actors through the utilization of e-commerce and social media. The method employed is Participatory Action Research (PAR), which includes stages of observation, socialization, training, and practical assistance. The program partners are MSME actors engaged in handicrafts and traditional food businesses, specifically tiwul, with success indicators including the ability to create and manage promotional accounts and produce simple digital content. The results show that participants are able to use platforms such as Facebook and TikTok Shop for promotion and create marketing content. In addition, business banners were developed to strengthen product identity. The impact of this program includes improved digital understanding and skills among MSME actors, expanded marketing reach, and increased business competitiveness. Furthermore, the program encourages the sustainable use of digital technology in business development.
Analisis Kinerja Keuangan Berdasarkan Rasio Profitabilitas PT Pertani (Persero) Mangkona, Suriyanti; Asri, Dandi; Salim, Ahmad; Ma’ruf, Muhammad; Wahyuddin, Wahyuddin
Amsir Management Journal Vol. 4 No. 1 (2023): Oktober
Publisher : Fakultas Bisnis Institut Ilmu Sosial dan Bisnis Andi Sapada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56341/amj.v4i1.242

Abstract

This study aims to determine & analyze financial performance based on profitability ratios at PT Pertani (Persero) Kab. Sidenreng Rappang. Data collection methods used in this research are observation, interview, and documentation methods. Types and sources of research data using quantitative data in the form of primary data and secondary data. This study uses profitability ratios with four indicators for calculating the value of financial ratios: (1) Gross Profit Margin (2) Net Profit Margin Earning Before Interest and Tax to Total Assets using profitability ratios, (3) Return On Assets (4) Return On Equity. The research results show that financial performance has not been efficient and effective, as seen from the 2018 Gross Profit Margin of 0.025%, 0.031% in 2019, and 0.021% in 2020. Net Profit Margin in 2018 was 0.014%, in 2019 it was -0.007%, and in 2020 it was -0.036%. Return On Assets in 2018 was 0.0026%, in 2019 it was -0.0015%, and in 2020 it was -0.0018%. Return On Equity in 2018 was 0.0025%, in 2019 it was -0.0016%, and in 2020 it was -0.0016%. PT. Agriculture (persero) Kab. Sidenreng Rappang must evaluate its current performance in utilizing assets and equity to maximize profit so that the company is able to make financial performance effective and efficient.
Aktivitas Antidiare Ekstrak Etanol Kulit Pisang Kepok (Musa Paradisica L.) terhadap Mencit Putih Jantan Agustin, Risma Indrika; Ariani, Novia; Ma’ruf, Muhammad
Borneo Journal of Medical Laboratory Technology Vol. 8 No. 2 (2026): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjmlt.v8i2.9371

Abstract

Diare adalah suatu kondisi di mana seseorang sering buang air besar dengan feses cair atau encer. Salah satu tanaman yang berpotensi sebagai antidiare adalah pisang kepok, terutama pada kulit buah pisang kepok. Kulit buah pisang kepok mengandung senyawa flavonoid, alkaloid, tanin, steroid dan saponin yang berpotensi dalam mengurangi konsetrasi gejala diare. Tujuan dari penelitian ini adalah mengetahui efek antidiare dan dosis ekstrak kulit pisang kepok pada mencit jantan. Jenis penelitian ini adalah eksperimental yang menggunakan hewan uji mencit jantan dengan berat badan 20-30 g sebanyak 24 ekor yang terdiri dari kelompok normal, kelompok kontrol negatif  Na-CMC 0,5%, kelompok kontrol positif loperamid 0,02mg/20g BB, kelompok ekstrak dosis 1 mg/20g BB, 1,3mg/20g BB, dan 1,5mg/20g BB. Penelitian ini menggunakan metode proteksi dengan induksi kombinasi oleum ricini 0,75mL dan magnesium sulfat 2mg/Kg BB secara oral. Parameter yang diamati diantaranya berat feses, konsistensi feses, dan frekuensi diare. Analisis data dilakukan menggunakan SPSS. Hasil penelitian ini menujukkan bahwa pemberian dosis 1 mg/20g BB, 1,3mg/20g BB, dan 1,5mg/20g BB memiliki efek sebagai antidiare. Berdasarkan hasil penelitian ini dapat disimpulkan bahwa ekstrak kulit pisang kepok memiliki aktivitas sebagai antidiare dengan dosis efektif 1,5mg/20g BB.
Co-Authors Abdulah, Zeni Malik Adam Prayogo Kuncoro Agustin, Risma Indrika Ahmad Salim, Ahmad Aisyah, Noor Alfiannor, M. Amartiwi, Utih Andini, Yulita Dian Anisa Devi Kharisma Wibowo Annisa Abdi Ghifari Any Guntarti Aprilia, Venny Ariani, Novia Asri, Dandi Baharuddin, Dahlia Chong, Rockie Citra Ariani Edityaningrum, Citra Efiana, Nuri Ari El Syam, Robingun Suyud Elviana, Windi Firman Firman Hadi Sumarsono Halimun, Naomi Kartikasari, Ayu Lifia Nur Khairi, Sabiah Kurniawan, Henny Laela Hayu Nurani Lalu Muhammad Irham Mangkona, Suriyanti Maria Ulfah Mas'ud, Masdar Maulana, Ronal Jusuphan Muhammad Hafizh Abiyyu Fathin Fawwazi Niah, Rakhmadhan Nida, Faridatun Normilawati, Normilawati Nugraha, Media Fitri Isma Isma Nur Jannah, Eka Yuni Nurjihan, Lu’lu Pranata, Satria Prihandiwati, Erna Priyatno, Aditya Rachman Pungkas Subarkah Puspitaningrum, Anisa Nova Putra, Alfiansyah Imanda Putri Ayu Lestari Rifqi Muntaqo, Rifqi Riski, Akhmad Rustandi, Tedi Salsabila, Suci Saputri, Olyfiah Nazzwa Saputri, Vivi May Sari, Sukma Kumala Sekar Ayu Wulandari Sianu, Rahman Sumani Siswanto, Lalu Muhammad Harmain Susanto, Yugo Susilo, Yudi Hardi Wahyuddin Wahyuddin Wahyudi Wahyudi Wahyuni, Amaliyah Wahyuningtyas, Nurma Widodo, Arif Nur Wirawan Adikusuma Woro Supadmi Yumassik, Abdul Mahmud