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Analisis Genom untuk Identifikasi Penyakit Langka di Indonesia Dedy Arisjulyanto; Gerson Andrew Warnares
Journal of New Trends in Sciences Vol. 1 No. 2 (2023): Mei: Journal of New Trends in Sciences
Publisher : CV. Aksara Global Akademia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59031/jnts.v1i2.774

Abstract

Rare diseases present a significant challenge in diagnosis due to their low prevalence and the limited awareness among healthcare professionals. The emergence of genomic technologies, particularly Next-Generation Sequencing (NGS), has revolutionized the diagnosis of rare diseases by enabling the identification of genetic variations associated with these conditions. This technology offers improved accuracy and speed compared to traditional clinical diagnostic methods, which are often time-consuming and insufficient for rare genetic conditions. This study explores the application of genomic technology in identifying rare diseases in Indonesia, highlighting its effectiveness, accuracy, and the challenges involved in its implementation. The research employed genomic testing techniques, including whole-genome sequencing (WGS), to identify genetic mutations associated with rare diseases in patients. The findings of the study demonstrate that genomic technology significantly reduces the time required for diagnosis, providing a more comprehensive understanding of the genetic conditions. Diseases such as Diphyllobothriasis and Sparganosis, which are rarely diagnosed through traditional clinical methods, were successfully identified using genomic technologies. However, challenges persist in the implementation of genomic technology in Indonesia, including limited infrastructure, high costs, and a lack of specialized training for healthcare professionals. Despite these barriers, the findings underscore the potential of genomic technologies to improve the diagnosis and management of rare diseases in Indonesia. The study concludes by recommending further investments in infrastructure, the training of healthcare professionals, and the development of supportive policies to facilitate the widespread adoption of genomic technologies in the healthcare system, particularly for the diagnosis of rare diseases.
Pemberdayaan Masyarakat Pesisir dalam Pencegahan Malaria pada Anak di Kampung Turu Wilayah Kerja Puskesmas Serui Kota Arisjulyanto, Dedy; Mesa, Nofita Dewi Kok; Istyanto, Febry; Siregar, Neny San Agustina
Jurnal Kemitraan Masyarakat Vol. 2 No. 4 (2025): Desember : Jurnal Kemitraan Masyarakat
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/jkm.v2i4.2509

Abstract

Malaria remains a significant health issue in the coastal areas of Yapen Islands Regency, particularly among children who are at high risk of morbidity and mortality. To address this, a community empowerment and mentoring activity was conducted in Kampung Turu, the service area of Serui Kota Health Center, with the aim of increasing knowledge and practices related to malaria prevention through a community-based education approach. The program involved 60 respondents and was carried out in three stages: preparation, implementation, and monitoring and evaluation. The interventions included malaria education, demonstrations on the use of insecticide-treated bed nets, environmental management, and training community health workers as education agents. Pre–post test evaluations showed an improvement in community knowledge and awareness regarding malaria prevention in children. The community empowerment approach was proven effective in promoting positive behavioral changes and enhancing the capacity of parents and health workers to carry out sustainable malaria prevention efforts. This program is expected to serve as a model for public health interventions in coastal areas aimed at reducing the risk of malaria in children.  
KNOWLEDGE OF DENTAL AND MOUTH HEALTH WITH THE BEHAVIOR OF ARECA NUT CHEWING OF ADOLESCENTS IN YAPEN ISLANDS REGENCY Dedy Arisjulyanto; Yohanis R. Tipawael; M. Parawangsa; Ellen R. V. Purba
International Journal Of Health Science Vol. 2 No. 3 (2022): November: International Journal of Health
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/ijhs.v2i3.784

Abstract

Background: Dental and oral health problems in the community, one of which arises because of behavioral factors or attitudes of ignoring dental and oral hygiene. In Indonesia, dental and oral health problems are relatively high, based on data from the 2018 Basic Health Research that 57.6% of the Indonesian population has dental and oral health problems with 10.2% of dental health workers. Papua Province has dental and oral health problems as of 48. The lowest tooth brushing behavior in Indonesia is 54.4% from the national data of 94.7% with a ratio of dental medical personnel still very low at 8%. Methods: The design of this study used a cross-sectional study, the sample used the Probability Proportional Size sampling technique and obtained 90 respondents, and the data analysis in this study used the chi-square test. Results: Based on the results of research and discussion in this study, the distribution of respondents with knowledge of Dental and oral health with the poor category as much as 58.9%, the sufficient category 20%, and the good category as much as 21.1%, the distribution of respondents who have chewing betel nut behavior is 66.7%, and do not have betel nut chewing behavior 33.3%, and the results of the analysis using the chi-square test obtained p-value 0.000 < = 0.05. Conclusion: there is a relationship between the level of knowledge of respondents about dental and oral health with betel nut chewing behavior in the Yapen Islands Regency. It is necessary to do health promotion about dental and oral health in the Yapen Islands Regency. It can increase the knowledge and behavior of adolescent health in maintaining dental and oral health in the Yapen Islands Regency.
SOCIALIZATION AND APPLICATION OF THE FLIPPED CLASSROOM LEARNING METHOD IN THE NURSING METHODOLOGY COURSE FOR NURSING STUDENTS OF THE JAYAPURA MINISTRY OF HEALTH POLYTECHNIC Ardhanari H. Kusuma; Dedy Arisjulyanto; Sri Mulyono
International Journal Of Health Science Vol. 2 No. 3 (2022): November: International Journal of Health
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/ijhs.v2i3.785

Abstract

Background: The current conditions are challenging to demand students to play an active role, get high marks, and have good nursing competence. It happens because the learning method is not exactly applied to increasing the interaction of students and lecturers in the classroom. Laboratory practicum is monotonous and carried out in a brief time also affects it. In addition, the lack of learning media makes student learning motivation very low. It has an impact on student passivity. They also do not understand the importance of learning and developing nursing competencies to become professional and dignified nurses. Method: The research design uses a Quasi Experiment. It is a research design with a purposive sampling technique. The purpose of this study was to find out the difference in the level of student knowledge before and after the application of the flipped classroom learning method. It conducted twice observations. They are before and after being given the flipped classroom learning method. The student's knowledge level was measured twice, namely before the flipped classroom learning method was applied (pre-test) and after the flipped classroom learning method was applied (Posttest). The sample in the study was 41 respondents. The research data were analyzed using the Paired T-Test with a significant traffic P value <α=0.05. Result: The results of the research on the application of the Flipped classroom learning method obtained a mean value of student knowledge of 35.36. There was an increase of 51.95 to 87.31, with a p-value of 0.000 <α=0.05. Conclusion: There is an influence of the application of the Flipped Classroom learning method on the level of knowledge of Nursing Students at Health Polytechnic Jayapura. In this research, the researchers hoped that it can be used as an evaluation material and become an effective learning method to increase students' knowledge and learning motivation at the Jayapura Ministry of Health Polytechnic.
Pengaruh Edukasi Berbasis Komunitas Terhadap Tingkat Pengetahuan Masyarakat tentang Pencegahan Malaria pada Anak Dedy Arisjulyanto; Nofita Dewi Kok Mesa; Frans Manangsang; Neni San Agustina Siregar; Ardhanari Hendra Kusuma
Jurnal Ners Vol. 10 No. 1 (2026): JANUARI 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i1.52203

Abstract

Malaria masih menjadi masalah kesehatan masyarakat di Papua, termasuk Kabupaten Kepulauan Yapen, dengan angka kasus yang tinggi pada anak. Tingkat pengetahuan masyarakat tentang pencegahan malaria berperan penting dalam menurunkan risiko penularan. Edukasi berbasis komunitas, seperti penyuluhan menggunakan media leaflet, terbukti dapat meningkatkan pengetahuan dan perilaku preventif masyarakat. Penelitian ini bertujuan mengetahui pengaruh edukasi berbasis komunitas melalui media leaflet terhadap tingkat pengetahuan masyarakat mengenai pencegahan malaria pada anak di Kampung Turu, Distrik Yapen Selatan, Kabupaten Kepulauan Yapen. Penelitian menggunakan pendekatan kuantitatif dengan desain pre-eksperimental one group pretest-posttest. Sampel sebanyak 30 responden dipilih dengan purposive sampling, memenuhi kriteria usia ≥18 tahun, berdomisili minimal satu tahun, dan bersedia mengikuti seluruh rangkaian penelitian. Instrumen berupa kuesioner pengetahuan dengan 10 item pilihan ganda yang telah diuji validitas dan reliabilitas. Data dikumpulkan melalui pretest, intervensi edukasi menggunakan leaflet, dan posttest, kemudian dianalisis dengan uji paired sample t-test pada tingkat signifikansi 0,05. Hasil menunjukkan rata-rata skor pengetahuan meningkat dari 10,34 ± 2,80 menjadi 17,34 ± 2,10, dengan peningkatan signifikan (t = 15,35; p < 0,001). Temuan ini menegaskan bahwa edukasi berbasis komunitas menggunakan media leaflet efektif meningkatkan pengetahuan masyarakat tentang pencegahan malaria pada anak. Intervensi ini disarankan diterapkan secara berkelanjutan dengan keterlibatan kader lokal untuk memperluas jangkauan pengetahuan dan perilaku preventif.