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Study of Creatinin Levels of Patients Receiving Antipsycotic Treatment at Mutiara Sukma Psychiatric Hospital, Nusa Tenggara Barat Sukmana, Dhika Juliana; Mentari, Ika Nurfajri; Anjelin, Desak Putu
Medicra (Journal of Medical Laboratory Science/Technology) Vol 4 No 2 (2021): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i2.1616

Abstract

Mental disorders are clinical and social problems that must be addressed immediately. Long-term use of the drug can cause damage to kidney function and worsen the work of the kidneys. Creatinine is a waste product of creatine phosphate metabolism that occurs in the muscles and is then released into the blood circulation, then transported to the kidneys. The purpose of this study was to determine how the creatinine levels of mental patients receiving antipsychotic treatment at Rumah Sakit Jiwa Mutiara Sukma Hospital, Nusa Tenggara Barat Province. The research method used is qualitative. The type of research used is descriptive, namely looking at data from the Clinical Pathology laboratory installation and medical records to determine the results of examination of creatinine levels in patients with mental disorders. The results showed that from data in the Clinical Pathology laboratory and medical records at Rumah Sakit Jiwa Mutiara Sukma, NTB Province from June-December 2020 with a total of 40 data, there were 30 patients (75%) who had normal creatinine levels, 2 patients (5%) had normal creatinine levels. creatinine levels were low, and 8 patients (20%) had high creatinine levels.
SOSIALISASI PROSEDUR PEMERIKSAAN LABORATORIUM DAN TERAPI ANTIBIOTIK PADA PENYAKIT TUBERCULOSIS Mentari, Ika Nurfajri; Ustiawaty, Jumari; Aini, Aini; Idawati, Sri; Pertiwi, Ajeng Dian; Ulya, Tuhfatul; Hijriani, Baiq Isti
Jurnal Pengabdian Masyarakat Sehati Vol. 3 No. 1 (2024): Juni
Publisher : Politeknik Medica Farma Husada Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33651/jpms.v3i1.676

Abstract

Tuberkulosis (TBC) merupakan penyakit menular yang masih menjadi masalah kesehatan masyarakat utama di dunia, termasuk di Indonesia. Pengendalian TBC memerlukan pendekatan terpadu, meliputi diagnosis yang akurat melalui pemeriksaan laboratorium dan penanganan yang tepat dengan terapi antibiotik. Oleh karena itu, pemahaman yang baik tentang prosedur pemeriksaan laboratorium dan penggunaan antibiotik yang tepat sangat penting bagi tenaga kesehatan dan masyarakat. Kegiatan sosialisasi ini dilakukan di Udayana dalam rangka car free day dengan tujuan untuk meningkatkan pengetahuan dan keterampilan terkait prosedur pemeriksaan laboratorium TBC, seperti tes mikroskopis, tes cepat molekuler, dan tes biakan, serta prinsip-prinsip penggunaan antibiotik sesuai pedoman nasional dan rekomendasi terkini. Melalui penyampaian materi dan diskusi peserta akan memperoleh pemahaman yang mendalam tentang langkah-langkah pemeriksaan laboratorium yang benar, interpretasi hasil, dan cara pemberian terapi antibiotik yang optimal pada kasus TBC. Sosialisasi ini diharapkan dapat meningkatkan kualitas diagnosis dan tatalaksana TBC, serta mendukung upaya pengendalian penyakit ini di masyarakat.
Pengaruh Pemberian Ekstrak Bengkuang (Pachyrhizus Erosus) sebagai Antioksidan terhadap Kadar Kolesteroltinggi pada Mencit (Mus Musculus) Fardani, Roushandy Asri; Mentari, Ika Nurfajri; Fitria, Eka
Jurnal Sains, Teknologi dan Kesehatan Vol. 3 No. 2 (2024): Jurnal Sains, Teknologi dan Kesehatan, April 2024
Publisher : LPPM Institut Teknologi Dan Kesehatan Aspirasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/saintekes.v3i2.327

Abstract

High cholesterol levels in the blood are a serious problem because they are a risk factor for various non-communicable diseases such as heart disease, stroke and diabetes mellitus. Empirically, the secondary metabolic contents of jicama such as saponins& flavonoids have their respective properties. Saponin functions to bind cholesterol with bile acids so that it can reduce cholesterol levels. The results of the antioxidant activity test, the IC50 value of jicama extract is 115.20 mg/mL, which indicates that the antioxidant activity of jicama extract is classified as a moderate antioxidant. The results of measuring cholesterol levels after treatment showed that there was a decrease in cholesterol levels after giving jicama extract treatment in each group, seen in treatment 1 (P1) at 113.4 with a difference of 2.6 from cholesterol before administration, treatment 2 (P2) at 110.8 with a difference of 4.6 of cholesterol before administration, treatment 3 (P3) was 110.6 with a difference of 7.6 from cholesterol before administration of jicama extract, positive control (K+) was 108.4 with a difference of 30.2 from cholesterol before administration, negative control (K-) was 122.6 with a difference of 0.2 antioxidants from purple cabbage, namely 115.20 μg/mL. The antioxidant activity of purple cabbage is in the very strong category and vitamin C is in the very strong category.
ANTIBACTERIAL ACTIVITY OF JAPANESE CAMBOJA (Adenium obesum) LEAF EXTRACT ON THE GROWTH OF THE BACTERI Sthaphylococcus aureus Lestari, Widya; Kurniawan, Edy; Ustyawati, Jumari; Mentari, Ika Nurfajri
Jurnal Penelitian dan Kajian Ilmiah Kesehatan Politeknik Medica Farma Husada Mataram Vol. 10 No. 1 (2024): April
Publisher : Politeknik Medica Farma Husada Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33651/jpkik.v10i1.692

Abstract

Staphylococcus aureus bacteria are microorganisms that can causing the most common infections such as skin infections. In the treatment of infections commonly use antibiotics, but there are often problems in use of antibiotics, leading to resistance. One way Preventing resistance is by looking for alternatives that are better cheap and efficient, one example is by using frangipani plants. (Adenium obesum). Japanese frangipani leaves themselves are believed to contain alkaloids, flavonoids and saponins that function as antibacterials. The purpose of this study was to determine the effect of giving Japanese frangipani leaf extract (Adenium obesum) on the growth of Staphylococcus aureus bacteria. This research method is a laboratory experiment by means of wells diffusion with concentrations of 50%, 25%, 15% and 10%. The results of this study indicate that there is no clear zone in each concentration. The conclusion is that Japanese frangipani leaves (Adenium obesum) are unable to inhibit the growth of Staphylococcus aureus bacteria.
Literature Review : Prevalensi Jumlah Leukosit Pada Sampel Urine Pasien dengan Pemasangan Kateter Putri, Pipit Sagita; Aini, Aini; Mentari, Ika Nurfajri; Pauzan, Pauzan
JSN : Jurnal Sains Natural Vol 3 No 1 (2025): Februari
Publisher : Puslitbang Sekawan Institute Nusa Tenggara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35746/jsn.v3i1.597

Abstract

The use of urinary catheters is very common in hospitals. Urinary catheters are the most common cause of bacteriuria. Urinary tract infections are the cause of more than 1/3 of all hospital-acquired infections. Most of these infections (at least 80%) are caused by invasive procedures or urinary tract instrumentation, usually in the form of catheterization. Urine sediment examination aims to detect and identify insoluble materials in urine. The purpose of this study was to determine the prevalence of leukocyte counts in patients with catheter placement based on a literature review and to analyze the number of leukocytes in patients with catheter users based on a literature review. The method used was Systematic Literature Review (SLR). The results of this study obtained the results of the number of samples based on gender in women as many as 223 people and in men 147 people, with a total number of patients as many as 370. then the results of the number of samples based on patient age, the number of patients who were most catheterized at the age of 56-65 as many as 101 patients (27.0%), followed by age 46-55 as many as 96 patients (25.0%), age 36-45 as many as 68 patients (18.0%), age 26-35 as many as 39 patients (10.0%), age 17-25 as many as 30 patients (8.0%), and age> 65 as many as 36 patients (9.0%) with a total of 370 patients. The results of the study can be concluded that catheter installation can cause urinary tract infections.
Erythrocyte Index Profile As An Indication of Anemia Based On Morphology In Patients (Tuberculosis) Undergoing Treatment Aini, Aini; Saptiana, Baiq Agustin; Pauzan, Pauzan; Mentari, Ika Nurfajri
JSN : Jurnal Sains Natural Vol 3 No 1 (2025): Februari
Publisher : Puslitbang Sekawan Institute Nusa Tenggara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35746/jsn.v3i1.598

Abstract

Tuberculosis is an infectious disease caused by the Mycobacterium tuberculosis bacteria which usually attacks the lungs but can also attack other organs such as lymph nodes, heart and so on. Tuberculosis is transmitted through the air, from one person to another, usually through the sputum droplets of someone who has had TB. Anaemia in Tuberculosis can be caused by disruption of the erythropoiesis process by inflammatory mediators, shortening of the life span of erythrocytes, impaired iron metabolism, malabsorption, and inadequate nutrition due to low appetite. The research method used is descriptive. Where this study will describe how the erythrocyte index is in tuberculosis patients who take medication for 1 month, 2 months, 3 months, 4 months, 5 months, and 6 months of treatment. The total respondents in this study were 20 respondents, including 10 men and 10 women. Based on the results of the erythrocyte index count, the type of erythrocytes shows the number of respondents with Hypochromic Microcytic anaemia as many as 6 people, Normochromic Microcytic anaemia as many as 3 people, Hypochromic Normocytic anaemia 1 person and Normochromic Normocytic anaemia as many as 10 people.
Profil differential count pada penderita hepatitis B di RSUD Patut Patuh Patju Kabupaten Lombok Barat aini, aini aini; Mentari, Ika Nurfajri; Zahrah, Laelatur
Jurnal Analis Medika Biosains (JAMBS) Vol 9, No 1 (2022): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v9i1.253

Abstract

Hepatitis B merupakan penyakit sistemik yang menyerang organ hati yang disebabkan oleh virus Hepatitis B, penyakit ini bersifat menular. Hepatitis masih menjadi masalah kesehatan di dunia terutama di Negara berkembang termasuk Indonesia. Hepatitis B dapat dideteksi dengan pemeriksaan immunokromatografi dan dilanjutkan dengan pemeriksaan differential count. Tujuan penelitian ini adalah untuk mengetahui profil differential count / hitung jenis leukosit pada penderita Hepatitis B. Penelitian ini bersifat Deskriptif Observasional Analitik dengan menggunakan desain penelitian Cross Sectional Analitik. Penelitian dilakukan di RSUD Patut Patuh Patju terhadap 48 sampel pasien hepatitis dengan HBsAg positif. Hasil yang didapat berupa pemeriksaan Differential count untuk jenis leukosit yang normal Basofil 46 orang (95,83%) Eosinofil 12 orang (25%) Neutrofil 19 orang (39,59%) Limposit 9 orang (18,75%) Monosit 35 orang (72,91%). Untuk jenis basofil tidak mengalami penurunan frekuensi 0 (0%), dan yang mengalami penurunan eosinofil 26 orang (54,16 %) neutrofil 1 orang (2,08%) limposit 39 orang (81,25 %) monosit 1 orang (2,08 %) .Jenis leukosit yang mengalami peningkatan basofil 2 orang (4,16%) eosinofil 10 orang (20,83 %) neutrofil 28 (58,33 %) limposit 0 (0%) monosit 12 orang (25 %). 
Mangrove Biofiltration as A Green Biotechnology for Wastewater Remediation: Targeting DO, BOD, COD, Phosphate, Detergent Mbas, and Ammonia Aini, Aini; Irawansyah, Irawansyah; Mentari, Ika Nurfajri; Maulana, Alfi; Ustiawaty, Jumari
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10385

Abstract

This Wastewater treatment plants are essential for reducing pollution before wastewater is discharged, but conventional systems often fail to achieve effective pollutant removal . This study aimed to measure the effectiveness of mangrove powder in treating industrial wastewater before it is discharged into the environment to improve wastewater quality. Samples were taken at two points: after conventional wastewater treatment and after treatment with mangrove biofiltration. The biofiltration system was designed to address the limitations of conventional treatment, particularly in reducing BOD₅, COD, phosphate, MBAS, and increasing dissolved oxygen (DO). Sampling was carried out using a  one liter sterile sample bottle. Sampling was carried out using a 1-liter sterile sample bottle. Sampling was carried out at one point with four repetitions. Parameters analyzed included TSS, pH, DO, BOD₅, COD, nitrate, nitrite, ammonia, phosphate, sulfate, and MBAS detergent. Mangrove biofiltration achieved reductions in TSS (55.26%), COD (99.35%), nitrate (100%), BOD₅ (99.15%), phosphate (96.67%), sulfate (99.55%), nitrite (100%), ammonia (90.00%), and MBAS (100%), while DO increased by 47.37% and pH remained stable. These improvements indicate the mangrove biofilter’s capacity to adsorb and biologically degrade organic matter and pollutants, enhancing wastewater quality to meet reuse standards. The results of the study show the potential of mangrove-based biofiltration as a solution for waste treatment units using mangrove biofiltration to reduce the concentration of DO, BOD, COD, phospat, Detergen MBAS, and Ammonis in industrial waste before being discharged into the environment.