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All Journal Medula Jurnal Kreativitas PKM Jurnal Ilmu Kedokteran dan Kesehatan JK Unila (Jurnal Kedokteran Universitas Lampung) Jurnal Pengabdian Kepada Masyarakat (JPKM) Tabikpun Buguh: Jurnal Pengabdian Kepada Masyarakat
Risti Graharti
Bagian Ilmu Patologi Klinik, Fakultas Kedokteran Universitas Lampung
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Episode Depresi Berat Dengan Gejala Psikotik Pada Wanita Berusia 17 Tahun: Sebuah Laporan Kasus rizki_novtarina21; Boy K.H, High; Graharti, Risti
Medula Vol 15 No 3 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i3.1674

Abstract

Major depressive episodes with psychotic symptoms are a form of major depressive disorder characterized by severe affective symptoms accompanied by delusions or hallucinations. This condition is relatively rare, but is associated with a poorer prognosis, a high risk of recurrence, and an increased suicide rate compared to depression without psychotic symptoms. This case report aims to describe the clinical manifestations, diagnostic process, and management strategies in patients with major depressive episodes accompanied by psychotic symptoms. The patient presented with feelings of depression, sadness, and lack of enthusiasm in performing daily activities for 1 year, which had worsened for 4 months prior to admission to the hospital, since the death of the patient's mother. The diagnosis was established based on a psychiatric interview, mental status examination, and diagnostic criteria from the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Management consisted of a combination of antidepressants and antipsychotics, as well as intensive psychosocial support. This report emphasizes the importance of early detection, accurate diagnosis, and comprehensive management to reduce the risk of complications, improve the patient's quality of life, and reduce the recurrence rate. Thus, this case study is expected to serve as an additional reference in the clinical management of major depressive disorder with psychotic symptoms.
Update on Hypertension Guidelines: A Literature Review Andika, Gede Agus; Graharti, Risti
Medula Vol 15 No 3 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i3.1682

Abstract

Hypertension is one of the major worldwide health problems, with its prevalence continuing to increase year by year. This condition is known as the “silent killer” because it often does not cause specific symptoms, but is closely related to increased morbidity and mortality due to cardiovascular and non-cardiovascular complications. Various epidemiological studies show that hypertension contributes to high rates of coronary heart disease, stroke, kidney failure, and premature death. Recent literature also confirms that risk factors for hypertension include unhealthy lifestyles, high-salt diets, obesity, stress, and genetic predisposition. The diagnosis of hypertension requires accurate blood pressure measurement using standard protocols, either through examinations at healthcare facilities or self-monitoring at home. Various international guidelines, such as ACC/AHA, ESC/ESH, and national guidelines such as PERKI, emphasize the importance of early detection and blood pressure control with specific targets. Hypertension management strategies include non-pharmacological approach such as lifestyle modifications, as well as pharmacological approach using evidence-based antihypertension medications, such as diuretics, ACE inhibitors, ARBs, CCBs, and beta blockers. This literature concludes that hypertension management must be comprehensive, integrated, and sustained to prevent complications. These efforts does not only depend on medical interventions, but also involve patient education, routine monitoring, and health system support to reduce the burden of hypertension in the future.
Co-Authors Agatha Catherine Agustyas Tjiptaningrum Airlangga Damara Andi Nafisah Andika, Gede Agus Angga Wijaya, Angga Annisa Fath Ari Wahyuni Arif Yudho Prabowo Arnida Rahman Asep Sukohar Aulia Berliana Avisa Jinan Azura Ayu, Putu Ristyaning Benny Syahputra Gumay betta kurniawan Boy K.H, High Diaru Fauzan Farizy Disaputera, Alfafa Tsalaatsa Dorisman, Hari Dwiki WIjaya Rahman Evi Kurniawati Fatmasari, Dina Femmy Adrifianie Gigaramadan Sema Happy, Terza Aflika Helmi Ismunandar Idris, Mohamad Intanri Kurniati Jati, Pandu Kumaya Khairun Nisa Kurniawaty, Evi Kusumaningrum, Desy Liana Sidharti, Liana Maharani, Atifah Fadilah Muhammad Ihsan Fariqy Muhammad Maulana Novita Carolia Nurul Utami Oktoba, Zulpakor Putri, Syalika Dianisa Putu Ristyaning Ayu Rachman Aziz Rahmat, Aprin Nabila Rani Himayani Rani Himayani Rasmi Zakiah Oktarlina Ratna Dewi Puspita Sari Reni Indriyani rizki_novtarina21 Rodiani Roro Rukmi Windi Sany Setiawan Septiani, Linda Setiawan, Putri Ayundari Sheira Indah Anjani Soemarwoto, Retno Ariza Soeprihatini Sutarto Sutarto Syazili Mustofa TA Larasati Winda Trijayanthi Utama, Winda Trijayanthi