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Meditory : The Journal of Medical Laboratory
Published by Poltekkes Kemenkes Denpasar
ISSN : 23381159     EISSN : 25491520     DOI : https://doi.org/10.33992/meditory
Core Subject : Science, Social,
Biochemistry, Genetics & Molecular Biology Environmental Science
Meditory : The Journal of Medical Laboratory secara khusus berfokus pada masalah utama dalam pengembangan ilmu di bidang laboratorium medis yang mencakup patologi klinik, mikrobiologi, kimia kesehatan dan patologi anatomi.
Arjuna Subject : -
Articles 165 Documents
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COMPARISON OF POCT AND HEMATOLOGY ANALYZER METHODS FOR HEMOGLOBIN LEVEL EXAMINATION IN SECOND TRIMESTER PREGNANT WOMEN AT TUMPANG HEALTH CENTER fitria, diva anggi
Meditory : The Journal of Medical Laboratory Vol 12, No 2 (2024): Meditory, Volume 12 No. 2 Tahun 2024
Publisher : Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/meditory.v12i2.3772

Abstract

Hemoglobin is a component of the protein molecule in erythrocyte cells that distributes oxygen (O2) throughout the body. Hemoglobin contains iron which makes blood red. HB levels are a supporting examination that helps establish a diagnosis as a reflection of the body's reaction to a disease and as an indication of the progress of therapy for anemia sufferers and other diseases. Method: This type of research is descriptive research with a cross sectional design. The sample collection technique used the Accidental Sampling technique with a sample population of 22 pregnant women in the second trimester at the Tumpang Community Health Center. Results: The results of research on hemoglobin levels using the POCT method and Hematology Analyzer using the dependent T test showed a significant comparison of p value 0.01 (0.05). The average POCT Hb level result was 1.55 g/dl and the average hematology analyzer Hb level result was 1.82 g/dl. The Hematology Analyzer method is more accurate because the average result obtained is higher than POCT.Conclusion :Suggestions for further research can be used Different samples and a larger number of samples require comparative examination of HB levels using other methodssahli, cyanmethemoglobin, and tallquist.
PHYTOCHEMICAL AND ANTIMICROBIAL ACTIVITY TESTS OF TURMERIC TINCTURE AS A DISINFECTANT FOR MEPANDES CEREMONIAL EQUIPMENT IN BALI Widiari, Ni Nyoman; Tata Arini, Ni Putu Dewi; Karta, I Wayan
Meditory : The Journal of Medical Laboratory Vol 12, No 1 (2024): Meditory, Volume 12 No. 1 Tahun 2024
Publisher : Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/meditory.v12i1.3077

Abstract

Background: In the traditional Mepandes ceremony of Bali, one of the key practices involves the use of sangging equipment, including chisels, files, and sharpeners, to smoothen teeth surfaces. Typically, one set of sangging tools is shared among 3-10 individuals, rotating their use. This practice poses a potential risk of disease transmission. The current cleaning methods vary, with some using water and turmeric while others soak the equipment in 5% NaOCl. However, the use of water alone may not ensure proper hygiene, and NaOCl usage presents challenges such as equipment odor and potential health hazards.Aims: The objective of this study is to qualitatively analyze the phytochemical content, inhibitory activity, and total plate count in turmeric tinctures at concentrations of 5%, 10%, and 15% Methods: The tincture is prepared by soaking turmeric simplicia in 70% alcohol for 5 days at concentrations of 5%, 10%, and 15%. In this study, the negative control is 70% alcohol, the positive control is 5% NaOCl, and the treatment includes tinctures at 5%, 10%, and 15%. Phytochemical tests include flavonoid, tannin, saponin, terpenoid, and alkaloid assays. Antimicrobial activity is assessed through total plate count (TPC) and inhibition tests. The results The research results indicate the presence of tannin, flavonoids, and phenols in all three treatments. Based on the antibacterial tests and total plate count, all three tincture solutions can be used as disinfectants. However, for efficiency, a 5% concentration is recommended as it exhibits the same antibacterial strength as the 10% and 15% tinctures.Conclusions:The use of turmeric tincture treatment can be employed as a disinfectant for ceremonial tools since it can inhibit the growth of S. aureus bacteria, and its total plate count value matches that of the positive control.
HEMATOPOIETIC EFFECTS OF ETHANOLIC EXTRACT FROM Alternanthera sissoo ON ERYTHROCYTE, HEMOGLOBIN, AND HEMATOCRIT LEVELS IN ANEMIA-INDUCED FEMALE WISTAR RATS Ratih, Gusti Ayu Made; Aryastuti, Anak Agung Sri Agung; Suryaningsih, Putu Ayu; Dwi Agustini, Desak Gede; Habibah, Nur
Meditory : The Journal of Medical Laboratory Vol 13, No 2 (2025): Meditory, Volume 13 No. 2 Tahun 2025 (On Progress)
Publisher : Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/meditory.v13i2.4714

Abstract

Background: Maternal anemia remains a primary global health concern due to its association with adverse pregnancy outcomes and the increased risk of iron deficiency anemia in infants, which may impair neurodevelopment and growth. Although iron supplementation is the standard therapy, its gastrointestinal side effects often limit treatment adherence. Therefore, Brazilian Spinach (Althernanthera sissoo), a plant rich in iron, flavonoids, and antioxidants, offers potential as a natural alternative.Objective: This study aimed to evaluate the hematopoietic effects of the ethanolic extract of Alternanthera sissoo on erythrocyte count, hemoglobin concentration, and hematocrit levels in female Wistar rats (Rattus norvegicus) induced with anemia.Methods: A quasi-experimental study using a completely randomized design (CRD) was conducted with three treatment doses (5, 7.5, and 10 mg/kg body weight). Hematological parameters (Erythrocyte count, Hemoglobin (Hb), and Hematocrit (HCT)) were analyzed using a Hematology Analyzer, followed by statistical testing with one-way ANOVA and Duncan’s Multiple Range Test (DMRT) at a 5% significance level.Results: The 10 mg/kg BW treatment produced the most significant improvement in erythrocyte count, Hb, and HCT levels compared to the other groups.Conclusions: Ethanolic extract of Althernanthera sissoo effectively enhances hematological indices in iron-deficient rats, showing strong potential as a natural nutraceutical supplement for preventing anemia during pregnancy.
DIAGNOSTIC VALIDITY ANALYSIS OF NS1-BASED RAPID TEST COMPARED WITH RT-PCR FOR DENGUE DETECTION IN BATAM Inderiati, Dewi; Yanti, Yuli; Sofia, Anita; Anhar, Citra Amaniah
Meditory : The Journal of Medical Laboratory Vol 13, No 2 (2025): Meditory, Volume 13 No. 2 Tahun 2025 (On Progress)
Publisher : Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/meditory.v13i2.4801

Abstract

Background: Dengue remains a significant health problem in Indonesia, including Batam. Because its symptoms resemble other infections, early laboratory testing is crucial. The non-structural protein one rapid diagnostic test (NS1 RDT) is widely used, but its accuracy depends on the day of illness, immune status, and viral serotype.Objective: To evaluate the diagnostic validity of NS1 RDT compared to RT-PCR, assessing the level of agreement between the two methods, and analysing the influence of clinical phase and serotype on the results of the examination.Methods: A retrospective analytic study used secondary data from 309 suspected dengue cases tested by NS1 RDT at primary care and confirmed by RT-PCR with serotyping at Batam Public Health Laboratory (2022–2024). Diagnostic performance was calculated from 2×2 tables; concordance was analysed with McNemar's test and Cohen's kappa.Results: The NS1 RDT showed 75.8% sensitivity, 81.2% specificity, 62.7% positive predictive value, 88.9% negative predictive value, and 79.6% overall accuracy, with moderate agreement with RT-PCR (κ = 0.54). NS1 positivity peaked on illness days 1–3 and varied by serotype, with the highest for DENV-3.Conclusions: The NS1 RDT showed good diagnostic validity with moderate agreement and sensitivity and high specificity in early dengue disease screening compared to RT-PCR, so the diagnostic performance of the NS1 RDT can be used in local epidemiological testing in Batam.
ASSOCIATION BETWEEN FASTING BLOOD GLUCOSE AND C-REACTIVE PROTEIN LEVELS IN TYPE 2 DIABETES MELLITUS PATIENTS Devi, Komang Ayu Aishvarya Gangga; Sewar, Caroline Ester; Krisna, Luh Ade Wilan; Rakhmawati, Aprilia
Meditory : The Journal of Medical Laboratory Vol 13, No 2 (2025): Meditory, Volume 13 No. 2 Tahun 2025 (On Progress)
Publisher : Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/meditory.v13i2.4903

Abstract

Background: Diabetes mellitus (DM) is characterized by elevated blood glucose levels resulting from decreased insulin secretion by pancreatic beta cells. Fasting blood glucose (FBG) measurement is commonly used to monitor DM, requiring patients to fast for a minimum of eight hours. Insufficient insulin production impairs glucose uptake into body tissues, leading to hyperglycemia. Chronic hyperglycemia subsequently stimulates the production of inflammatory cytokines, which promotes the hepatic synthesis of C-reactive protein (CRP).Objective: This study aims to determine the relation between FBG and CRP levels in patients with type 2 diabetes mellitus (T2DM) at Mangusada Hospital.Method: An observational analytic study was conducted using purposive sampling, with a total sample of 25 T2DM patients.Result: The lowest FBG level was 126 mg/dL, while the highest was 319 mg/dL. The lowest CRP level was 0.2 mg/L, whereas the highest was 23.7 mg/L. High FBG and CRP levels were observed in 44% of respondents, while high FBG with normal CRP levels were found in 56%. The highest FBG (319 mg/dL) also exhibited the highest CRP level (23.7 mg/L) The non-parametric Spearman’s rank correlation revealed a significant association between FBG and CRP levels with p-value of 0.012 (0.05) and r = 0.493 indicated a positive and moderate correlation.Conclusion: There is a positive, moderate correlation between FBG and CRP levels in T2DM patients at Mangusada Hospital. KeywordsC-Reactive Protein, blood glucose, diabetes

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