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Journal of Islamic Medicine
Published by Universitas Islam Negeri Maulana Malik Ibrahim Malang
ISSN : -     EISSN : 25500074     DOI : https://doi.org/10.18860/jim
Core Subject : Health,
Medicine & Pharmacology
Journal of Islamic Medicine is a medical journal published twice a year in March and September by the School of Medicine, Faculty of Medicine and Medical Sciences, Universitas Islam Negeri Maulana Malik Ibrahim Malang.
Arjuna Subject : -
Articles 156 Documents
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Hubungan antara Pengetahuan tentang Hukum Perawatan Ortodonti dalam Pandangan Islam terhadap Persepsi Tenaga Pendidik Pondok Pesantren Modern terkait Perawatan Ortodonti Nafsih, Thoharoh Laili; Handayani, Fani Tuti; Nurlaela, Nurlaela; Wardhianna, Sotyania; Purnama, Ryana Budi
Journal of Islamic Medicine Vol 7, No 2 (2023): JOURNAL OF ISLAMIC MEDICINE EDISI SEPTEMBER 2023
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v7i2.21150

Abstract

Background: Malocclusion is a condition of occlusion deviation which is still the third-highest dental and oral health problem in Indonesia. The high prevalence of malocclusion in Indonesia has not been followed by public awareness to perform orthodontic treatment. The awareness and behavior of people to get treatment can be influenced by knowledge and perceptions. Objective: to analyze the relationship between knowledge about the laws of orthodontic treatment according to Islamic perspective and the perceptions of modern Islamic boarding school teachers regarding orthodontic treatment Methods: This study used an analytic observational method with a cross-sectional approach. The research was conducted at Zam-Zam Muhammadiyah Cilongok Islamic Boarding School. Sample selection was carried out using the simple random sampling technique with the inclusion and exclusion criteria. Knowledge and perceptions are measured using the questionnaire. A total of 78 teachers participated in this study and 50 respondents who met the criteria were obtained. Data analysis was performed by descriptive and inferential analysis using the Chi-square test. Results: The data obtained shows that the knowledge of teachers is dominated by knowledge in the good category (52%) and there are no respondents in the bad category of knowledge. Perceptions of teachers are dominated by moderate perceptions (68%) and there are no respondents in the bad category of perceptions. The results of the Chi-square test obtained a value of p = 0.000 (p
Aktivitas Anti Trombotik dari Genus Curcuma : Kajian Sistematik Sandhori, Fajar Jamaluddin; Kusumawati, Idha; Samirah, Samirah; Rullyansyah, Subhan; Ramadhani, Firmansyah Ardian; Prasetyawan, Hanif Rifqi; Warsito, Mega Ferdina
Journal of Islamic Medicine Vol 8, No 2 (2024): JOURNAL OF ISLAMIC MEDICINE EDISI SEPTEMBER 2024
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v8i2.25929

Abstract

Background : The Curcuma genus has various pharmacological activities, one of these is antithrombotic activity by preventing thrombus formation. Some of its chemical contents are also known to inhibit thrombus formation including curcumin, bisdemethoxycurcumin, ar-turmerone, and xanthorrizhol compounds. Antithrombotic drugs are used for the prevention and treatment of thrombosis whose mechanisms are divided into anticoagulants, thrombolytics, and antiplatelets. Objective: This review article discusses the potential of Curcuma genus as antithrombotic, including anticoagulant, antiplatelet, and thrombolytic, Methods: This study was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method using four databases : PubMed, ScienceDirect, Scopus, and Google Scholar from July to December 2023. The inclusion criteria used were articles on antithrombotic activity, including anticoagulants, antiplatelets, and thrombolytics from the genus Curcuma. Results: The number of articles obtained from four databases was 3413 articles. Furthermore, based on the results of filtering duplicate articles from all databases, 2771 articles were selected and then continued with screening based on inclusion and exclusion criteria until 15 articles were selected as material for systematic review. Conclusion: Curcuma species that have potential as antithrombotic are Curcuma longa, Curcuma zedoaria Rosc., Curcuma amada, Curcuma caesia, Curcuma aeruginosa, Curcuma latifolia, Curcuma aromatica Salisb, Curcuma wenyujin, and Curcuma xanthorrhiza
THE EFFECT OF TURMERIC ACID ON PERINEAL WOUND HEALING IN POSTPARTUM WOMEN IN PMB KARANGPLOSO AREA, MALANG DISTRICT salama, asaluka billah
Journal of Islamic Medicine Vol 8, No 1 (2024): JOURNAL OF ISLAMIC MEDICINE EDISI MARET 2024
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v8i1.21207

Abstract

Perineal rupture is a laseration or wound that develops along the perineum during the delivery process, which can occur accidentally or intentionally. (episiotomi). Perineum wounds resulting in childbirth can potentially cause infection because the germs enter through the seams. Kunyit works in several stages to speed up wound healing. Curcuma domestica Val contains curcumin compounds that can accelerate re-epithelisation, cell proliferation, and collagen synthesis. (Wientarsih et al, 2012). Java acid works as an antibacterial, anti-inflammatory, analgesic and antioxidant activity. The aim is to analyze the effect of acid turmeric on the healing of perineal wounds in postpartum mothers. The method used in this study is the type of pre-experiment with design intact-group comparison. The study used variables with two groups, including the experimental group and the control group. The sample totaled 32 mothers with a perineal injury. The results of the study were that the average wound healing control group got 3-5 REEDA scores of 8 people with presentations (50%) and the experimental group got 0-2 REEDE scors of 14 people with presentation (87,5%). The Mann-Whitney Statistical Test was conducted by Asymp. Sig. (2-tailed) / p.value is worth 0,000. Because the value is 0,000 of 0.05, it means there is an effect of acid curcumin on the healing of perineal wounds.
Uji Efektivitas Kombinasi Ekstrak Daun Kemangi (Ocimum x africanum Lour.) dan Daun Pandan Wangi (Pandanus amaryllifolius Roxb.) Terhadap Larva Aedes aegypti Wati, Ria Widya; Nofita, Nofita; Marcellia, Selvi
Journal of Islamic Medicine Vol 8, No 1 (2024): JOURNAL OF ISLAMIC MEDICINE EDISI MARET 2024
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v8i1.23293

Abstract

Basil leaves and fragrant pandanus leaves have secondary metabolite compounds namely alkaloids, flavonoids, saponins, tannins, and terpenoids that can be natural larvicides. The purpose of this study was to determine the activity, effectiveness and LC50 value of the combination of basil leaf extract (Ocimum x africanum Lour.) and fragrant pandanus leaf (Pandanus amaryllifolius Roxb.) as larvicide of Aedes aegypti mosquitoes. Extraction using maceration method with 96% ethanol solvent. This study used 5 treatments, namely negative control (distilled water), positive control (abate 1%), FI ( Basil leaf extract 1% concentration + fragrant pandan leaves 2% concentration), FII (Basil leaf extract 1,5% concentration + fragrant pandan leaves 1,5% concentration), and FIII (Basil leaf extract 2% concentration + fragrant pandan leaves 1% concentration) each treatment containing 25 Aedes aegypti instar III larvae with 5 repetitions. Data obtained will be analyzed by one way ANOVA test, Post Hoc Test LSD (Least Significance Different) test, and Probit test. The results of the effectiveness test on FIII with a mortality value of 100%, said to be effective in killing Aedes aegypti larvae. The results of the one way ANOVA test showed significant differences in average concentrations, then the results of the LSD Post Hoc Test showed that the FIII concentration had larvicidal effectiveness that was not significantly different from the positive control, this can be seen from the significant value of 1.000 (p>0.05) against the positive control. The probit test results showed an LC50 value of 1.715% which means that the combination of basil leaf extract (Ocimum x africanum Lour.) and fragrant pandanus leaf (Pandanus amaryllifolius Roxb.) has toxic properties as a natural larvicide Keyword : Basil Leaf, Fragrant Pandanus Leaf, Larvicide, Aedes aegypti
Penetapan Kadar Senyawa Epikatekin dalam Ekstrak Air Kulit Batang Faloak (Sterculia quadrifida R.Br.) Berbagai Varian sebagai Antihepatitis C Dean, Muhajirin; Telussa, Arley Sadra; Malelak, Elric Brahm
Journal of Islamic Medicine Vol 8, No 2 (2024): JOURNAL OF ISLAMIC MEDICINE EDISI SEPTEMBER 2024
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v8i2.28895

Abstract

Background: East Nusa Tenggara Province, Indonesia, is a common location for the faloak plant. Due to its epicatechin compounds, the faloak plant (Sterculia quadrifida R.Br) has potential for use as an anti-hepatitis C treatment. Objective: This study aims to identify the highest epicatechin content of faloak obtained from various places, to optimize the cultivation and processing of faloak plants into herbal antihepatitis C medicines. General therapy for hepatitis C causes side effects such as hemolytic anemia, pruritus, asthenia, neutropenia, myalgia, respiratory problems, cardiovascular disorders, and even teratogenic. Methods: Faloak plants obtained from 3 locations (Rote, Timor, and Semau Islands) were extracted with water solvent. The extracts were then analyzed by HPLC to measure epicatechin levels using standard. Results: All three samples from different islands demonstrated the presence of epicatechin, as indicated by their retention times matching the standard compound. The retention times for the Faloak water extracts from Rote, Timor, and Semau Islands were 12.420, 12.427, and 12.353, respectively. The assay results revealed that the sample from Rote Island had the highest concentration, measuring 24.810%. Conclusion: All faloak water extracts contain epicatechin, with the highest concentration found in faloak from Rote Island.
Uji Stabilitas dan Antibakteri Spray Nanoemulsi Ekstrak Bunga Telang (Clitoria Ternatea L.) dengan Variasi Polietilen Glikol (Peg) 400 Sari, Rizki Tribuana; Ulfa, Ade Maria; Elsyana, Vida
Journal of Islamic Medicine Vol 8, No 1 (2024): JOURNAL OF ISLAMIC MEDICINE EDISI MARET 2024
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v8i1.23292

Abstract

Nanotechnology has been used in drug delivery systems because it can improve drug penetration and absorption. PEG 400 can reduce interfacial tension and create a stable nanoemulsion system that also increase the ability of the active substance to inhibit bacterial growth. The purpose of this study was to identify the stability of spray nanoemulsion preparations of (Clitoria ternatea L.) with variations of PEG 400 and test the antibacterial activity against Staphylococcus epiermidis. Extraction using maceration method then freeze dried the yield obtained was 29.33%. The preparation was carried out physical evaluation test, antibacterial test of disc diffusion method, and stability test. The results of the stability test showed the results of the pH test, spreadability, dry time and viscosity did not experience significant differences (P>0.05). At organoleptic and tests, only F1 was the most stable and preferred preparation. The inhibition zone activity hedonic of spray nanoemulsion preparation with a concentration of 15% amounted to 9.84±0.44 mm, 20% concentration of 10.70±0.65 mm, 25% concentration of concentration was 12.24±0.61 mm. The results of the antibacterial test analyzed using Kruskal-Wallis obtained a significant value of 0.013, which means that there is a significant difference the average value of the bacterial inhibition zone between each treatment group. Spray nanoemulsion of F1 telang flower extract with PEG 400 (15%) showed the most stable physical quality and antibacterial properties.
Formulation and Evaluation of Halal Non-Aromatic Moisture and Protection Cream Preparations for Hajj and Umroh Pilgrims Annisa, Rahmi; Anggraini, Wirda; Purwaningsih, Fauziyah Eni; Salsabila, Dhia Fadhilah; Samah, Moh.Alfin; Mutiah, Roihatul
Journal of Islamic Medicine Vol 8, No 2 (2024): JOURNAL OF ISLAMIC MEDICINE EDISI SEPTEMBER 2024
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v8i2.26427

Abstract

Background: Protective moisturizer cream can be used by Hajj and Umrah pilgrims.They can use sunscreen moisturizer cream as a moisturizer and sunscreen to protect their skin from exposure to the sun because it does not contain alcohol or certain fragrances. Objective: This research aims to determine the halalness of ingredients, the presence or absence of aromatic content, the suitability of physical characteristics, and the effectiveness of the SPF value of halal non-aromatic Sunscreen moisturizer cream preparations using pre-experimental design research methods. Methods: The physical characteristics were evaluated, including organoleptic, homogeneity, spreadability, adhesive power, pH, and viscosity. Results: The organoleptic test results show that the Sunscreen moisturizer cream preparation has a yellowish-white color, is scentless, and has a soft texture. Homogeneity testing shows that this preparation is homogeneous. The spreadability test value of the preparation is 6.50 cm; the sticking power value is 3.77 seconds; the pH value is 5.00; the viscosity value is 5.64 cPs. The research results also show that the preparation contains halal ingredients and does not contain fragrances. Halal non-aromatic sunscreen moisturizer cream. Formula SPF value 38.332 ± 1.526 with ultra protection type. Conclusion: All evaluations of the physical characteristics of the Sunscreen moisturizer cream preparation have met the requirements for a good cream preparation, except for the viscosity test. It contains halal ingredients and has ultraprotective protection against UV light. Keyword : Cream, Sunscreen, Moisturizer, Non Aromatic, Hajj Care
Successful Intravitreal Injection of Ranibizumab for Age-Related Macular Degeneration (AMD) in Young Adults: A Case Report Adnani, Basyar; Sumarta, Norma Hanifah; Famuji, Siti Roziah Ria; Khotimah, Alif Raudhah Husnul; Halim, Putri Aulawiya Rosyida; Hasan, Yuliono Trika Nur; Hutasoit, Lina Puspita
Journal of Islamic Medicine Vol 8, No 1 (2024): JOURNAL OF ISLAMIC MEDICINE EDISI MARET 2024
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v8i1.25838

Abstract

Background:  Age Related Macular Degeneration (AMD) is a chronic condition that specifically affects the central retina and is widespread in developed nations. The hypothesis suggests that as the population ages, the occurrence and impact of AMD will rise due to the significant risk factor of being over 55 years old, which is most prevalent among the elderly. Bevacizumab, ranibizumab, and aflibercept have established themselves as the gold standard of therapy. Case Report:  We present the case of a middle-aged man with age-related macular degeneration (AMD) and no concomitant diseases who showed remarkable improvement after intravitreal injection with patizra (ranibizumab). A 44-year-old Asian man was administered Patizra injections for three consecutive months after developing age-related macular degeneration. After intravitreal injection of ranibizumab, this patient's health markedly improved, as seen by a reduction in subretinal fluid. Conclusion:  The intravitreal injection of ranibizumab has demonstrated efficacy in the treatment of age-related macular degeneration in middle-aged adults.
Peran Vitamin D Terhadap Kanker: Sebuah Tinjauan Literatur Umami, Zahra; Suharjono, Suharjono
Journal of Islamic Medicine Vol 8, No 2 (2024): JOURNAL OF ISLAMIC MEDICINE EDISI SEPTEMBER 2024
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v8i2.26058

Abstract

Vitamin D is a potent steroid hormone precursor that regulates a broad spectrum of physiological processes in the body. Besides its general role in bone metabolism, vitamin D plays an important role in the prevention and treatment of many diseases such as cancer. The aim of this literature review is to examine in more depth the role of vitamin D as an anticancer. There are studies that reveal biological mechanisms mediated by vitamin D in regulating cancer cells, such as cell renewal, cell proliferation, cell differentiation, cell transformation, and cell death. Other studies have also revealed a link between the immune system and the anti-neoplastic effects of vitamin D. Research shows that low levels of vitamin D in circulation are associated with an increased risk of cancer. The use of supplementation alone or in combination with immunotherapy or other chemotherapy may promote better clinical outcomes. These promising results still require further development and research through novel approaches targeting vitamin D signaling and metabolic systems to improve cancer therapeutic outcomes.
Uji Aktivitas Antioksidan dan Skrining Fitokimia Ekstrak N-Heksana Buah Genitri (Elaeocarpus ganitrus Roxb. ex G.Don ) dengan Metode DPPH Bhagawan, Weka Sidha; Ramdhani, Alfina Widya; Suproborini, Arum; Primiani, Cicilia Novi; Pujiati, Pujiati
Journal of Islamic Medicine Vol 8, No 1 (2024): JOURNAL OF ISLAMIC MEDICINE EDISI MARET 2024
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v8i1.26469

Abstract

Latarbelakang: Antioksidan merupakan senyawa yang mampu berfungsi dalam menangkal radikal bebas serta meningkatkan sistem imun dan kekebalan tubuh. Selain itu, buah genitri memiliki efek farmakologis yang meliputi antiinflamasi, antidiabet, antimikroba.Tujuan: Untuk mengetahui nilai IC50 serta senyawa metabolit sekunder yang terkandung didalam buah genitri dengan pembanding asam askorbat.Metode:Menggunakan metode ekperimental laboratorium dengan pengujian antioksidan menggunakan metode DPPH. Hasil: Nilai IC50 dengan katagori sangat kuat  sebesar  40,75 mg/ml, sedangkan nilai IC50 asam askorbat berkatagori sangat kuat sebesar 1,96 mg/ml. Pada uji skrining fitokimia buah genitri mengandung senyawa alkaloid, flavonoid, dan tanin yang memiliki peranan penting dalam aktivitas antioksida. Analisis hasil uji one way anova yaitu nilai sig 0,048 0,05 yang menunjukan bahwa hasil tersebut terdapat perbedaan yang signifikansi antara aktivitas antioksidan buah genitri dengan asam askorbat. Kesimpulan: Dapat dijadikan sebagai penangkal radikal bebas dalam tubuh.

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