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Jurnal Riset Ilmu Kesehatan Umum dan Farmasi
Published by Sekolah Tinggi Ilmu Kesehatan Kesetiakawanan Sosial Indonesia
ISSN : 30265819     EISSN : 30265800     DOI : 10.57213
Core Subject : Health,
Health Professions Public Health
Jurnal ini adalah Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) yang bersifat peer-review dan terbuka. Bidang kajian dalam jurnal ini termasuk riset Ilmu Kesehatan Umum, dan Farmasi.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 184 Documents
 9   10   11   12   13 
Analysis of the Differences in Unit Costs for Bronchopneumonia Services Based on Clinical Pathway with INACBGs Rates and Hospital Rates at Dr. RSAL. Mintohardjo Jack Steven Saripantung; Rokiah Kusumapradja; Intan Silviana
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 1 (2025): Januari : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i1.552

Abstract

Hospital is one of the health service facilities that tries to overcome the health service balance between investment costs and the availability of applicable unit costs. Calculation of unit costs has an important role, including being used for budget planning, cost control, subsidies and as information in decision making. In the era of National Health Insurance (JKN) in Indonesia, Hospitals that cooperate with the Social Security Administering Agency (BPJS) Health are paid using the Indonesian Case Base Groups (INACBGs) package system. The acquisition of claim payments at Dr. Mintohardjo Naval Hospital according to the INACBGs rate compared to Hospital costs has a negative difference value for Bronchopneumonia cases. The purpose of this study was to analyze the difference in unit costs of Bronchopneumonia services based on Clinical Pathway towards the determination of INACBGs Rates and Hospital Rates at Dr. Mintohardjo Naval Hospital. This type of research is quantitative, comparative analytical observation using a cross-sectional research design according to the Hospital perspective. The subjects of the study were Medical Records and BPJS Kesehatan claim files for Bronchopneumonia services for the period April to September 2023, totaling 61 files. The study was conducted from January 2024 to April 2024. Data analysis used the paired t-test statistical method in the statistical test application (SPSS Version 26). The results of the study on calculating unit costs using the Activity Based Costing (ABC) method are as follows: 1) There is a difference between the calculation of unit costs with INACBGs rates of negative 6.2% and unit costs with Hospital rates of positive 11.2%, 2) There is a difference in the unit cost of Bronchopneumonia services based on Clinical Pathway with the Activity Based Costing method against INA-CBGs Rates, 3) There is a difference in the unit cost of Bronchopneumonia services based on Clinical Pathway with the Activity Based Costing method against Hospital Rates. The suggestions in this study are: 1) For the financial management of RSAL Dr. Mintohardjo to improve competence in calculating unit cost rates for services based on clinical pathways with the Activity Based Costing method, one of which is through training, 2) Updating and conducting clinical pathway audits periodically, 3) Re-evaluating hospital rates to increase the margin of each service so that the margin obtained is in accordance with what has been set, 4) Digitizing patient usage data that was previously still written manually to avoid errors in entering details of service costs.
Formulasi Sediaan Body Scrub Ekstrak Etanol Daun Salam (Syzygium Polyanthum (Wight.) Walp) dan Serbuk Beras Putih (Oryza sativa L.) Sebagai Pelembab Kulit Monica Suryani; Julia Susanti; Dumartina Hutauruk
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 2 No. 4 (2024): Oktober: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v1i4.558

Abstract

Body scrub is a pharmaceutical preparation in the form of a beauty product that functions to smooth the skin of the body and remove damaged skin cells with the help of scrubs. Bay leaf (Syzygium polyanthum (Wight.)Walp) and white rice powder (Oryza sativa L.) are plants that are widely used to maintain health, as a traditional medicine and also as an antioxidant. The research method carried out is experimental. The purpose of this study was to formulate ethanol extracts of bay leaf (Syzygium polyanthum (Wight.)Walp) and white rice powder (Oryza sativa L.) in the form of Body Scrub preparations with concentrations 2, 4, and 6 that can be used as a skin moisturizer. The extract sample uses ethanol solvent, which will be formulated into the form of a Body Scrub preparation, then an examination of the physical quality test of the preparation, irritation test, hedonic test, moisturiser effectiveness test using a skin moisture analyzer is carried out. The results of this study show that the ethanol extract of bay leaf (Syzygium polyanthum) and white rice powder (Oryza sativa L.) can be formulated as a Body Scrub preparation that has met the physical quality requirements of the preparation which has a semi-solid shape, a more concentrated preparation color and a distinctive aroma of bay leaf extract. The preparation shows a homogeneous composition, M/A cream type, spread power range 5.7-6.2 cm, viscosity range 3,800- 4000 cPs, pH 6.4-6.7, non-irritating to the skin and stable in storage for 4 weeks of storage, hedonic value that is very preferred by researchers on the Body scrub F3 preparation. The effectiveness test showed an increase in humidity of 31.59%, which was the best in the preparation of F3 concentration. It can be concluded that the ethanol extract of bay leaf (Syzygium polyanthum (Wight.)Walp) and white rice powder (Oryza sativa L.) can be formulated in Body Scrub preparations that have met the physical quality requirements of the preparation as a skin moisturizer at a concentration of 6%.
Formulasi dan Uji Penetrasi In Vitro Sediaan Gel Sistem FitosomEkstrak Buah Asam Jawa (Tamarindus indica L.) Devina Chandra; Cut Masyithah Thaib; Steven Tandiono; Manuppak Irianto Tampubolon
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 2 No. 4 (2024): Oktober: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v2i4.559

Abstract

Tamarind fruit extract (Tamarindus indica L.) contained flavonoids such as quercetin as antioxidants. The hydrophilic nature of tamarind fruit (Tamarindus indica L.) led to poor penetration and low bioavailability. Research was conducted to address penetration issues by preparing a phytosome drug delivery system incorporated into tamarind fruit extract formulations. The study aimed to formulate a tamarind fruit extract gel with phytosome preparation to enhance the effectiveness of active ingredient penetration. Phytosome preparation was carried out using the thin layer hydration method with concentrations of 1.5%, 3%, and 4.5%. Evaluation of the gel preparations showed that the color of FI (1.5%) was yellowish-brown, F2 (3%) was light brown, and F3 (4.5%) was dark brown. All formulations had a distinctive odor, pH ranged from 4.3 to 5.2, viscosity ranged from 4,333 to 7,500 cPs, spreadability ranged from 5.2 to 5.8 cm, and they had good stability, were homogeneous, and did not cause irritation. Penetration tests using Franz diffusion cells were performed on male rabbit skin (Oryctolagus cuniculus). The penetration results were analyzed using UV-Vis spectrophotometry with a maximum wavelength of 435 nm. The cumulative amount penetrated was 13.2085 ppm for F1 (1.5%), 14.2142 ppm for F2 (3%), and 15.5136 ppm for F3 (4.5%). In contrast, the tamarind fruit extract gel without phytosomes had a cumulative penetration amount of 1.3684 ppm. The tamarind fruit extract's phytosome gel showed better penetration than the tamarind fruit extract gel without phytosomes.
Formulasi dan Uji Aktivitas Antibakteri Sediaan Gel Antijerawat Ekstrak Etanol Daun Sisik Naga (Drymoglossum piloselloides (L.) Pressl.) terhadap Staphylococcus aureus Suharyanisa Suharyanisa; Widya Fitri; Nuranti Rumela; Betharina br Tarigan
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 2 No. 4 (2024): Oktober: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v2i4.560

Abstract

Acne appears due to increased sebum production on the skin and the growth of Staphylococcus aureus bacteria. The antibacterial activity of ethanol extract of dragon scale leaves (EEDSL) against Staphylococcus aureus bacteria provides strong inhibitory power. Dragon scale leaves (Drymoglossum piloselloides(L.) Pressl.)) can act as an anti-acne and its use as a preparation has not been widely carried out. This study aims to determine that EEDSL can be formulated as a gel preparation that meets the physicochemical quality requirements and that EEDSL gel preparations have antibacterial activity against Staphylococcus aureus. This study was conducted using an experimental method, sampling using the purposive sampling method in Kidupen Village, Juhar District, Karo Regency. Dragon scale leaf extract was obtained using the maceration technique with an ethanol solvent. EEDSL was formulated into a gel and then subjected to physical evaluation tests and antibacterial tests on staphylococcus aureus bacteria by looking at the diameter of the inhibitory power formed. The results of the study showed that the formulation of the anti-acne gel preparation was colorless, clear, and odorless obtained at F0. At F1; F2; and F3, a brown gel preparation was obtained with a semi-solid form and a distinctive EEDSL smell. The antibacterial activity test of EEDSL against Staphylococcus aureus showed an average value ± SD of the inhibition zone in each formula, namely at F0: 0.00 ± 0.00 mm; F1: 6.86 ± 0.17 mm; F2: 8.46 ± 0.19 mm; F3: 9.17 ± 0.18 mm; and positive control: 14.09 ± 0.23 mm. Based on the results of the data obtained, it can be concluded that EEDSL can be formulated as a gel preparation that meets the physicochemical quality requirements. Each concentration of ethanol extract of dragon scale leaves (Drymoglossum piloselloides (L.) Pressl.) has antibacterial activity against Staphylococcus aureus with a medium category.
Formulasi Sediaan Emulgel Ekstrak Daun Tanaman Leunca (Solanum nigrum) Sebagai Antibakteri Staphylococcus aureus pada Kulit Jon Kenedy Marpaung; Manahan Situmorang; Yanti Musyawarah; Natanael Priltius
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 2 No. 4 (2024): Oktober: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v2i4.563

Abstract

Emulgel is a moisturizing topical preparation that is able to soften the skin and protect it from damage. The leaves of the leunca plant have antibacterial and anti- inflammatory properties. Staphylococcus aureus is a gram-positive bacteria that can be found on human skin. This research aims to find out whether leunca (solanum nigrum) leaf extract can be formulated into an emulgel preparation that meets physicochemical quality, find out whether the resulting emulgel preparation of leunca leaf extract (solanum nigrum) can act as an antibacterial for staphylococcus and find out whether there are differences in the concentration of leunca leaf extract emulgel preparations. (solanum nigrum) affects its effectiveness as an antibacterial for Staphylococcus. This research method used. This research was carried out experimentally with emulgel preparations from leunca leaf extract with concentrations of 2%, 4% and 6% with emulgel evaluation. Based on the experimental results, it was concluded that leunca (solanum nigrum) leaf extract could be formulated F0, F1, F2 and F3 to meet the Organoleptic Test, Homogeneity Test, pH Test, Adhesion Test, Spreadability Test, Viscosity Test and Irritation Test. The emulgel preparation formulation from leunca (solanum nigrum) leaf extract showed potential as an antibacterial for Staphylococcus aureus with a DDH value greater than 20 mm, namely 20,31 to 21,83.
Analisis Aktivitas Antioksidan Ekstrak Daun Katang-Katang (Ipomea pes caprae) dengan Metode DPPH : Literature Review Tsania Zahra Taslima; Zulpakor Oktoba; Atri Sri Ulandari; Muhammad Iqbal
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 1 (2025): Januari : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i1.594

Abstract

Free radicals are reactive molecules that contribute to oxidative stress, triggering cellular damage and leading to degenerative diseases such as cancer, diabetes, and cardiovascular diseases. Antioxidants are required to neutralize free radicals and protect the body from oxidative damage. The leaves of Ipomoea pes-caprae (L.) R. Br. contain secondary metabolites, such as flavonoids and phenolics, which have potential antioxidant activity. This article aims to analyze the antioxidant activity of Ipomoea pes-caprae leaf extract using the DPPH method. The study employed a literature review approach using Google Scholar with specific keywords and 13 articles met the inclusion criteria with a  publication range from 2015 to 2025. The findings indicate that the extraction method and type of solvent significantly affect the effectiveness of antioxidant activity. Maceration and Soxhlet extraction methods were effective in isolating active compounds, particularly flavonoids and phenolics, while polar solvents such as ethanol and methanol produced better results compared to non-polar solvents. Antioxidant strength, determined by IC50 values, ranged from very strong to very weak. Therefore, it can be concluded that selecting the appropriate extraction method and solvent is crucial to maximizing the antioxidant potential of Ipomoea pes-caprae leaves as a natural antioxidant source for health and pharmaceutical applications.  
Potensi Aktivitas Antidiabetes Berbagai Jenis dan Varian Tanaman Mangga (Mangifera spp.) Agnes Monica Murisla; Zulpakor Oktoba; Femmy Andrifianie; Ramadhan Triyandi
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 2 (2025): April : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i2.595

Abstract

Diabetes mellitus is a chronic disease with a significantly increasing global prevalence, especially in developing countries. Current treatments use synthetic antidiabetic drugs that are generally expensive and have various side effects. This study aims to examine the potential of mango plants (Mangifera spp.) as antidiabetic agents through a systematic literature review. Literature searches were conducted through the electronic databases PubMed and Google Scholar using the keywords "Mangifera/mango" and "antidiabetic". From the search results, 25 relevant articles were obtained for further review, consisting of 15 articles on in vitro testing and 10 articles on in vivo testing. The search results identified 17 mango plant variants worldwide that have been shown to have antidiabetic activity. Each mango species has unique characteristics and different nutritional content and bioactive compounds. Various parts of the mango plant, including leaves, fruits, seeds, and bark, contain bioactive compounds such as flavonoids, tannins, saponins, and terpenoids. These compounds contribute to antidiabetic activity through several mechanisms, namely inhibition of α-glucosidase and α-amylase enzymes, increased insulin sensitivity, and reduced blood glucose levels. Mango plant secondary metabolites are not only effective, but also have the potential to be an alternative antidiabetic treatment that is more affordable and safe compared to synthetic drugs. It can be concluded that Mangifera spp. has great potential to be developed as an innovative diabetes therapy. Further research through clinical trials is needed to confirm its effectiveness as an antidiabetic agent.
Penentuan Nilai Sun Protection Factor (SPF) Ekstrak Air dan Kloroform Daun Kelor (Moringa oleifera L.) Litta ‘Ifina; Fadilah Qonitah; Risma Sakti Pambudi
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 2 (2025): April : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i2.596

Abstract

Moringa (Moringa oleifera) is a plant that is easy to grow in lowlands that contains phenolic compounds and flavonoids that have the potential to be sunscreen. The purpose of this study is to determine the activity of sunscreen from water extract and chloroform of moringa leaves as seen from the SPF parameters. The process of making extracts by infusion and maceration methods. Testing of SPF values with the UV-Vis spectrophotometer method. The SPF (Sun Protection Factor) value was determined using a UV-Vis spectrophotometer by measuring absorbances from concentrations of 50 ppm, 100 ppm, 150 ppm, 200 ppm, and 250 ppm water extract solutions and chloroform moringa leaves at wavelengths (290-320 nm) every 5 nm intervals with ethanol pa as a blank. The calculation of the SPF (Sun Protection Factor) value uses the Mansyur equation. The experiments that have been carried out have obtained results that there is sunscreen activity with the highest SPF value in water extract with a concentration of 250 ppm of 7.97 (extra protection) and in chloroform extract with a concentration of 250 ppm of 8.72 (ultra protection). Based on this study, it can be concluded that chloroform extract has a higher SPF value content compared to moringa leaf water extract at the same concentration.
Kandungan Senyawa Fitokimia dan Aktivias Antioksidan dari Ekstrak Daun Alpukat (Persea americana Mill.) : Narrative Review Michelle Jovelyna My Angel Pasaribu; Ihsanti Dwi Rahayu; Muhammad Iqbal; Ari Sri Ulandari
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 2 (2025): April : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i2.597

Abstract

Avocado leaves have long been used by Indonesian people as traditional medicine. Many studies have shown that the plant has many active compounds that have the potential to prevent cell damage caused by free radicals. The purpose of this narrative review article is to collect and review references related to the phytochemical compound content and potential antioxidant activity of avocado leaf extract (Persea americana Mill.). The search and review of literature used in writing this article was carried out by searching for reference sources by combining relevant keywords such as "antioxidant AND persea americana leaves* AND extract" on database sites such as NCBI, ScienceDirect, and Google Scholar. There are inclusion criteria used, namely articles in English and Indonesian, available in full text form, discussing secondary metabolite compounds of avocado leaf extract using the maceration method, and discussing antioxidant activity tests using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. Based on the search results, there are 7 articles that have met the inclusion criteria and have been reviewed. The results of this narrative review obtained information that there were several studies that conducted antioxidant activity tests on avocado leaf extract using the DPPH method with an IC50 value range of 6.7-440.80 µg/ml and there were polyphenol compounds, especially quercetin and kaempferol which contributed to the antioxidant activity of avocado leaves.
Kandungan Senyawa Fitokimia dan Aktivitas Antibakteri Ekstrak Daun Pepaya (Carica Papaya L.): Narrative Review Umniyah Tsabitah Zahrani; Ihsanti Dwi Rahayu; Atri Sri Ulandari; Ramadhan Triyandi
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 2 (2025): April : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i2.599

Abstract

This narrative review article explores the potential of papaya leaves (Carica papaya L.) as an alternative antibacterial treatment due to the increasing problem of antibiotic resistance. Papaya leaves, commonly found in Indonesia, are known to have various pharmacological properties, including antibacterial effects. The article aims to collect and review existing literature on the phytochemical compounds and antibacterial activity of papaya leaf extract. Literature searches were conducted across several databases such as Google Scholar, NCBI, ResearchGate, and ScienceDirect using keywords like "antibacterial," "phytochemical screening," and "Carica papaya leaf." Articles from the last five years that were accessible in full text and relevant to the topic were selected, leading to the inclusion of 18 articles in the review.The findings indicate that papaya leaf extracts exhibit antibacterial properties against both gram-positive and gram-negative bacteria. The degree of antibacterial activity varies, ranging from weak to very strong inhibition. This antibacterial effect is attributed to the secondary metabolite compounds present in papaya leaves, including alkaloids, flavonoids, saponins, tannins, phenolics, terpenoids, and steroids. These compounds contribute to the biological activity of the extract, making it a promising candidate for further development as a natural antibacterial agent. Overall, this review underscores the importance of exploring medicinal plants like papaya leaves as viable alternatives to combat bacterial infections and address the growing issue of antibiotic resistance..

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