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Global Medical and Health Communication
Published by Universitas Islam Bandung
ISSN : 23019123     EISSN : 24605441     DOI : https://doi.org/10.29313/gmhc
Core Subject : Health, Science,
Dentistry Health Professions Immunology & microbiology Nursing Public Health
Global Medical and Health Communication is a journal that publishes research articles on medical and health published every 4 (four) months (April, August, and December). Articles are original research that needs to be disseminated and written in English. Subjects suitable for publication include but are not limited to the following fields of anesthesiology and intensive care, biochemistry, biomolecular, cardiovascular, child health, dentistry, dermatology and venerology, endocrinology, environmental health, epidemiology, geriatric, hematology, histology, histopathology, immunology, internal medicine, nursing sciences, midwifery, nutrition, nutrition and metabolism, obstetrics and gynecology, occupational health, oncology, ophthalmology, oral biology, orthopedics and traumatology, otorhinolaryngology, pharmacology, pharmacy, preventive medicine, public health, pulmonology, radiology, and reproductive health.
Arjuna Subject : Kedokteran - Epidemilogi
Articles 422 Documents
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Patient Safety Incident Reporting Challenges in Indonesian Private Hospitals Listiowati, Ekorini; Arini, Merita; Nurmansyah, Mochamad Iqbal; Rachmawati, Emma; Samsudin, Agus
Global Medical & Health Communication (GMHC) Vol 12, No 1 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i1.12158

Abstract

Reporting patient safety incidents is essential in improving learning and patient safety. It is necessary to identify reporting challenges to improve the reporting process's success. This study assessed the challenges of patient incident reporting and learning systems in Indonesian private hospitals. This qualitative participatory action research is used. In October 2022, data was collected using a videoconferencing application. This study included 34 quality improvement and patient safety team members from 22 private hospitals. In this study, inductive analysis was used. The challenges of patient safety incident reporting are examined in six categories in this study: reporting environment, reporting rules and content, analysis and investigation, governance, action and learning, and patient and family engagement. The challenges mostly come from reporting environment components such as reporting difficulty and ignorance, a lack of time for analysis, the fear of making a mistake in the reporting process, and insufficient management support. Multiple challenges were encountered in different patient safety incident components. A positive environment for reporting patient safety incidents needs a multifaceted approach, including increased hospital leadership commitment and policies and procedures.
Cardiac Histopathology Alterations Induced by Subchronic Mangosteen Rind Extract in Wistar Rats Ratwita, Welly; Nurrokhmawati, Yanti; Maheswari, Endah Nabilah
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13445

Abstract

Mangosteen (Garcinia mangostana L.) is renowned for its potent antioxidant characteristics, including free radical scavenging, and its antibacterial, antifungal, anti-inflammatory, and antidiabetic properties. This study aims to assess the subchronic toxicity effects of ethanol extract from mangosteen rind on the cardiac histopathology of male and female Wistar rats. This research was a posttest-only control group design. Forty biological specimens from 40 Wistar rats were divided into four groups, a control group, and three treatment groups, which were given ethanol extract of mangosteen rind with doses of 250 mg/kg, 500 mg/kg, and 1,000 mg/kg for 28 days. Cardiac specimens were prepared and examined using hematoxylin-eosin (HE) staining at the Anatomical Pathology Laboratory of Universitas Jenderal Achmad Yani in December 2021. The findings indicated that prolonged ingestion of large amounts of ethanol extract from mangosteen rind can cause toxic effects characterized by an inflammatory response in cardiac tissue. No fibrosis or hypertrophy was detected; however, inflammatory changes such as the presence of inflammatory cells, vacuolar changes, and neovascularization were observed. The inflammation observed might be due to excessive antioxidant administration leading to oxidative stress. Inflammatory cells may trigger fibrotic remodeling in the heart. The difference in the quantity of inflammatory cells between male and female rats suggests that gender influences the inflammatory response. Overall, administration of ethanol extract from mangosteen rind at doses of 250 mg/kg, 500 mg/kg, and 1,000 mg/kg cause subchronic toxicity effects on the heart histopathology of Wistar rats, marked by inflammation.
Correlation of NLR and D-dimer Levels with Clinical Severity of COVID-19 and Determination of Cut-off Values at a Hospital in Cirebon Sari, Fitria Ratna; Nilapsari, Rika
Global Medical & Health Communication (GMHC) Vol 12, No 1 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i1.12279

Abstract

Inflammation and coagulation markers play a crucial role in assessing the systemic involvement of COVID-19. Early identification of disease severity through neutrophil-lymphocyte ratio (NLR) and D-dimer levels can aid physicians in promptly identifying potentially severe cases and determining appropriate treatment strategies. This study explored the relationship between NLR, D-dimer levels, and clinical severity in COVID-19 patients. This retrospective cross-sectional study reviewed 237 medical records of adult COVID-19 patients treated at Permata Cirebon Hospital from July to October 2021. The seriousness of COVID-19 served as the outcome variable, while NLR and D-dimer values were considered independent variables. Correlation analysis examined the relationship between NLR, D-dimer, and COVID-19 severity. Receiver operating characteristic (ROC) curve analysis was employed to establish the cut-off values. The majority of COVID-19 patients exhibited moderate disease severity. Male gender, advanced age, and comorbidities such as diabetes, hypertension, CVD, and stroke were associated with a higher likelihood of severe disease. A significant positive correlation was found between NLR and disease severity, as well as between D-dimer and disease severity. Notably, the correlation between D-dimer and disease severity was more substantial than that of NLR. Furthermore, the cut-off values obtained from the ROC analysis were 3.79 for NLR (sensitivity=68.8%, specificity=68.1%) and 1,110 for D-dimer (sensitivity=79.2%, specificity=87.5%). The study revealed a significant positive correlation between the severity of NLR, D-dimer levels, and COVID-19. Therefore, NLR and D-dimer can serve as prognostic markers for COVID-19 patients.
Effectiveness of Kegel Exercises on Perineal Wound Healing among Postpartum Women Rosyida, Desta Ayu Cahya; Hidyatunnikmah, Nina
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13736

Abstract

Perineal wound refers to a laceration or wound that occurs along the birth canal (perineum) due to the delivery process. Wound healing is a method involved in replacing and repairing damaged tissue's capacity. This study aims to determine the effectiveness of Kegel exercises on perineal wound healing. It was a quasi-experimental study with one group pretest-posttest design conducted in March–May 2023. Forty-five women with perineal wounds at the Arosbaya Public Health Center, a reputable healthcare facility in Bangkalan, East Java province, Indonesia known for its comprehensive postpartum care, were selected as the study samples through a random sampling technique. The pre-test was done by observing the perineal wound before doing Kegel exercises. At the intervention stage, respondents did Kegel exercises daily for seven days. The post-test was carried out on day 7, and then observation of the perineum wound was carried out. Data were collected using an observation sheet. T-test was applied for the statistical tests. The study results show that after carrying out Kegel exercises, the majority of the 45 respondents experienced changes; namely, 25 people experienced good wound healing, and the remaining 20 experienced poor wound healing. The calculated t value was higher than the t table value (−16.523>−2.015) and had a significance value of <0.05 (0.000<0.05). This study's findings have practical implications for postpartum care, as they highlight the potential of Kegel exercises in promoting perineal wound healing, thereby enhancing the knowledge and practice of healthcare professionals and postpartum women.
Stakeholder Insights on Malaria Elimination Strategies in Pangandaran, West Java: a Qualitative Analysis Faridah, Lia; Fauziah, Nisa; Adams, Fayyaza Faiz; Mufida, Hasna; Akbar, Muhamad Lazuardi; Salsabila, Pricillia Laurenza; Rufinus, Wilbert Bernardi; Virajati, Abimanyu Athallah; Angga, Anggisti Nurdinda Chaerany Putri; Mahira, Khansa; Zahra, Ridha Beta
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13483

Abstract

Indonesia has launched a determined effort to eliminate malaria by 2023, focusing on Java and Bali. Despite these efforts, Pangandaran in Java still faces malaria cases. This study aims to meticulously delve into the intricacies of the malaria elimination program's implementation while conducting a comprehensive evaluation of its effectiveness. Structured interviews were conducted with key stakeholders responsible for the malaria program in Pangandaran to extract invaluable insights. The study, carried out in November 2022, followed qualitative research with narrative analysis to reveal nuanced narratives from the participants. Findings from this rigorous analysis revealed a harmonious alignment between the malaria control program in Pangandaran and the Indonesian Ministry of Health guidelines. The strategy to combat malaria vectors in Pangandaran included mosquito net distribution, strategic larvicide application, and educational campaigns like Malaria Awareness Society (MASAMA). The expectation is that the current effective control program will resonate within the Pangandaran community, ultimately leading to the realization of the 2023 elimination target.
Vitamin D Levels and Their Correlation with Predisposing Factors and Estimated Fetal Weight in Third Trimester of Pregnancy: an Observational Study Indahwati, Dwiwahju Dian; Jasaputra, Diana Krisanti; Budiono, Arief; Gunadi, Julia Windi; Lesmana, Ronny; Kusmawan, Steven Zerin Putra
Global Medical & Health Communication (GMHC) Vol 12, No 1 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i1.11953

Abstract

Vitamin D has a broad impact on the human body, including affecting the bones and the immune system. Vitamin D deficiency in pregnant women is a risk factor in several circumstances, such as preeclampsia, gestational diabetes, premature birth, and low birth weight babies. This study aimed to determine the vitamin D levels and their relationship to predisposing factors and estimated fetal weight in the third trimester of pregnancy. Eighteen pregnant women in their third trimester of pregnancy who received antenatal care in the Obstetric Clinic of Immanuel Hospital Bandung from January to December 2022 were used as subjects of this study. The inclusion criteria are third-trimester pregnant women, healthy, while the exclusion criteria are currently taking drugs that have side effects in pregnancy or having pregnancy disorders. Blood was taken to measure vitamin D levels, fetal weight was estimated with obstetric ultrasound, and the subjects filled in questionnaires about predisposing factors. The results showed ten pregnant women (56%) had vitamin D deficiency below 20 ng/mL in their third-trimester pregnancy. We found non-significant relationships (p>0.05) between predisposing factors (daily consumption of vitamin D, sun exposure, maternal age), estimated fetal weight, and vitamin D levels. This study concludes that 56% of pregnant women in their third trimester of pregnancy have vitamin D deficiency with no significant relationship with its predisposing factors and estimated fetal weight.
Impact of Propolis Administration on Osteocrin Expression and Osteoblast-to-Osteoclast Ratio in the Femurs of Rats Fed a High-fat Diet Widiyanti, Alvira; Tarawan, Vita Murniati; Lubis, Leonardo
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13833

Abstract

A high-fat diet (HFD) is associated with bone inflammatory processes that can affect bone remodeling balance. Osteocrin produced by periosteal osteoblasts correlates with osteoblast activity, is expressed on osteoblast-derived cells, and is localized in osteoblasts and young osteocytes. Propolis is an antioxidant and anti-inflammatory in bone remodeling by inhibiting proinflammatory factors NF-κB and COX-2, reducing inflammatory suppression of cytokines responsible for osteoclast differentiation and osteoblast apoptosis. The flavonoid content increases the production of nitric oxide and osteoprotegerin, which enhances osteoblastogenesis. This study determined the effect of propolis administration on bone formation and resorption in bone previously damaged by an HFD. This research was conducted in the Animal Laboratory of Postgraduate Building Dipati Ukur and Genetics and Molecular Laboratory Eycman Building, Faculty of Medicine, Universitas Padjadjaran. The research time was from January 2023–May 2024. Male Wistar rats were divided into four groups: normal chow diet (NCD), NCD with propolis administration, HFD, and HFD with propolis administration. The 12-week-old rats were given an HFD for 12 weeks and then treated with propolis at a 300 mg/kgBW dose for nine weeks. The administration of propolis increased the ratio of osteoblasts-osteoclast cells in the femur of the HFD rats but did not affect periosteal osteocrin expression.
Bacteriological and Antibiotic Susceptibility Profile of Urinary Tract Infection among Online Motorcycle Drivers in Jakarta, Indonesia Effendi, Ida; Robertus, Thomas; Samira, Jihan; Devita, Arleen; Kumala, Widyasari; Bella, Isa
Global Medical & Health Communication (GMHC) Vol 12, No 1 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i1.12311

Abstract

Urinary tract infection (UTI) is a bacterial infection that contributes significantly to morbidity rates. UTI is a health concern due to multidrug-resistant (MDR) organisms. Therefore, the profile of bacteria and antibiotic susceptibility patterns are very important to know in order to make the best treatment choice. Working as an online motorcycle (ojol driver) carries a risk of urinary tract infections. Online drivers are assumed to often hold their urination for short or long periods. The descriptive study with a cross-sectional design was conducted to obtain the prevalence of urinary tract infections, bacteria profile, and antibiotic susceptibility in urine specimens collected from Jakarta ojol drivers in September 2022–Maret 2023. Of 98 midstream urine specimens, 17 samples are considered to have UTI (17.34%). The identification of the 17 isolates shows that the microorganisms' distribution was more likely to be caused by gram-positive than gram-negative bacteria (70.60%). The causative bacteria were coagulase-negative Staphylococcus (17.65%), Escherichia coli (11.76%), and Enterococcus faecalis (11.76%). Our results showed that the prevalence of urinary tract infections in ojol drivers is high with the distribution of the causative organisms by coagulase-negative Staphylococcus, Escherichia coli, and Enterococcus faecalis and still showed good susceptibility to narrow-spectrum antibiotics such as cotrimoxazole.
Anti-hyperuricemia Potential of Ethyl Acetate Fraction from Ethanolic Stem Extract of Arcangelisia flava Fatmawati, Fatmawati; Saleh, Irsan; Parisa, Nita; Salni, Salni; Izzah, Puspita Nurul; Subandrate, Subandrate; Athiah, Medina
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13510

Abstract

Arcangelisia flava, with its secondary metabolites in flavonoids, has shown promising potential as an alternative treatment for hyperuricemia. The study aimed to determine the effectiveness of the ethyl acetate fraction from the ethanolic stem extract of Arcangelisia flava in inhibiting xanthine oxidase. This research, conducted at the Medical Basic Chemistry Laboratory Universitas Sriwijaya in September–December 2022, used in vitro study methods. The stem of Arcangelisia flava was extracted by maceration using ethanol. The ethanolic stem extract of Arcangelisia flava was then fractionated using n-hexane and ethyl acetate. The ethyl acetate fraction and ethanolic extract of Arcangelisia flava were measured to inhibit the xanthine oxidase using UV-vis spectrophotometry with allopurinol as a comparison. The IC50 was calculated by linear regression. The ethanol extract and ethyl acetate fraction have flavonoids, alkaloids, terpenoids, and quinones. The IC50 value of the ethanol extract was 30.04 ppm, the ethyl acetate fraction was 23.99 ppm, and the allopurinol was 17.16 ppm. The ethyl acetate fraction inhibited xanthine oxidase better than the ethanol extract. The study's significant finding is that the ethyl acetate fraction of the ethanolic stem extract of Arcangelisia flava strongly inhibits xanthine oxidase, offering a potential new avenue for treating hyperuricemia.
Smoking Habit and Coffee Consumption with Gastritis Incidence Rate at Productive Ages Wibowo, Elsi Septira; Margo, Eveline
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.12299

Abstract

Gastritis is a disease caused by an inflammation of the mucous and submucosal lining of the stomach. Several studies show that there is an influence of smoking habit and coffee consumption on gastritis incidence rate. The study was to determine the correlation between smoking habit and coffee consumption toward gastritis at productive ages. The research is an analytical observational study with a cross-sectional design conducted in Makale Health Center, South Sulawesi, in February 2020. Required data was gathered by conducting guided interviews using a questionnaire that includes age range, sex, and education level. Brinkman Index was used to measure smoking habits, coffee consumption, and gastritis questionnaire. Data was analyzed using a chi-square test with a significance level of p=0.05. From a total of 115 respondents, there are 69.6% included in the age range of 26–35 years old, 58.3% have mild smoking habits, 56.5% have severe coffee consumption, and 85.2% are suffering from gastritis. There is a relation between smoking habit (p=0.029) and coffee consumption (p=0.003) with gastritis (p<0.05). The conclusion is that there is a relationship between smoking habits, coffee consumption, and gastritis incidence.

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