cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
jip@uin-malang.ac.id
Editorial Address
Department of Pharmacy Building 2nd Floor, Faculty of Medicine and Health Sciences, 3rd Campus Universitas Islam Negeri (UIN) Maulana Malik Ibrahim Malang.
Location
Kota malang,
Jawa timur
INDONESIA
Journal of Islamic Pharmacy
Published by Universitas Islam Negeri Maulana Malik Ibrahim Malang
ISSN : 24605182     EISSN : 25276123     DOI : http://dx.doi.org/10.18860/jip
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Public Health
Welcome to Journal of Islamic Pharmacy (e-ISSN : 2527-6123) formerly Jurnal Farmasains (p-ISSN : 2460-5182) Department of Pharmacy, Universitas Islam Negeri Maulana Malik Ibrahim Malang, Indonesia. The journal was established in 2015 and online publication was begun in 2016. Since 2016, the journal has been published in English and only receives manuscripts in English.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 156 Documents
 4   5   6   7   8 
A Case Report of Parkinson’s Disease in a 70 year Man With Myasthenia Gravis Ahadi, Muhammad Yanuar; Hadi, Deby Wahyuning; Soemarno, Soemarno; Octavia, Evi
Journal of Islamic Pharmacy Vol 5, No 2 (2020): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v5i2.8813

Abstract

AbstractBackground:. Neurodegenerative diseases such as Parkinson’s disease (PD) have increasing incidence, due to lifespan expansion. The association between PD and Myasthenia Gravis (MG) is uncommon, and so far, since 1987, 26 cases have been reported.Case presentation: This is a report of a 70-year-old man was referred into the hospital with ptosis, disfagia and dispnea. He was diagnosed with Suspected Myasthenia Gravis, Post Stroke Trombotik, Parkinson’s Disease and Hypertension. The patient was admitted to the outpatient unit, received of treatment Pyridostigmine, Clopidogrel, Trihexylphenidil, Vitamine B1, Vitaminie B6, Vitamine B12 and Levodopa-Benserazide .Discussion: Treatment guidelines by using some guidelines are also drug doses and do not have adverse side reactions during treatment.Conclusion:. PD and MG very rarely occur together. case report or a series of brief cases reported in the literature, it is very important not to miss the diagnosis of MG in patients with PD, because the treatment implications are very important and greatly influence the prognosis. More basic research needs to be done to understand the pathogenesis of both diseases, to provide more therapeutic options and possibly change the approach of the patient, whose quality of life is determined by these two neurological diseases, which have an increased impact on increasing disabilityKey words: Parkinson disease; Myasthenia gravis; co‐occurrence; case report.
Kajian Efek Ekstrak Umbi Bawang Dayak (Eleutherine palmifolia (L.) Merr) sebagai Antikanker Muti'ah, Roihatul; Listiyana, Anik; Nafisa, Belia Bima; Suryadinata, Arief
Journal of Islamic Pharmacy Vol 5, No 2 (2020): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v5i2.9778

Abstract

Dayak onion (Eleutherine palmifolia (L.) Merr) is a typical plant in Central Kalimantan. This plant has been passed down for generations by Indonesian people for various treatments. The potential of dayak onions that have various pharmacological activities needs to be increased in their use as modern medicinal ingredients. The purpose of this literature study is to review the various uses, the secondary metabolites content, and the action mechanism as an anticancer both in vitro, in vivo, and in silico. The results of this literature study show that traditionally the Indonesian people use the bulbs for the treatment of breast cancer, colon cancer, hypertension, diabetes mellitus, stroke, fever, dysuria, intestinal inflammation, dysentery, boils, cysts, prostate, lowering cholesterol and triglycerides, breastfeeding and sexual disorders. In the empiric treatment of cancer, this plant is used by drying the bulbs and chewing it. Dayak onion bulbs (Eleutherine palmifolia (L.) Merr) are known to contain flavonoid compounds wich isoliquiritigenin, polyphenols group wich oxyresveratrol and naphtoquinon group, and its derivatives such as elecanacine, eleutherine, eleutherol, eleutherinol, eleutherinon, eleuthoside B, eletherinoside A which has anti-cancer activity. Pre-clinical studies with in vitro and in vivo mechanism showed that dayak onion bulbs (Eleutherine palmifolia (L.) Merr) extracts have pharmacological activities, which are anti-cancer that can inhibit cell signaling through apoptosis and cell cycle arrest. Also, the mechanism of in silico showed anti-cancer activity from the inhibition of VHR receptors, BCL-2 receptors, VEGFR-2 receptors and alpha estrogen receptors (ERα).
Management Therapy of ST-Segment Elevation Myocardial Infarction: A Literature Review Novrianti, Irma; Wijaya, Dhani; Mustamin, Faizal; Wijayanti, Sari
Journal of Islamic Pharmacy Vol 5, No 2 (2020): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v5i2.8989

Abstract

Coronary Heart Disease (CHD) is the cardiovascular disease due to plaque build-up in the coronary artery, reducing the blood follow to the heart. STEMI (ST-segment elevation myocardial infarction) is the CHD due to the ST-segment elevation in 12 and the cardiac marker elevation as Troponin I. The elevation is due to a blockage in the coronary artery, causing the blood perfusion and oxygen supply for the heart to decrease. The objective of the article review is to describe the correct STEMI therapy based on the research findings and references listed in the literary review. This review was made with the study of literature published in 1993-2019. Conclusion: STEMI therapy management is discomfort management and reperfusion therapy. The reperfusion therapy is aimed to recover the myocardial blood flow, to heal the heart, and to reduce the mortality level. The primary coronary artery reperfusion can be administered with the primary percutaneous coronary intervention (PCI). PCI can open a blockage in the coronary artery and has a good effect on the short-term and long-term clinical results. Besides, it reduces the death risk, myocardial infarction, or repetitive stroke. Meanwhile, reperfusion using fibrinolytics is conducted when PCI is unavailable. Moreover, anticoagulant, antithrombotic, and vasodilators are supporting therapies for STEMI patients to reduce chest pain and prevent reinfarction
Evaluasi Pelayanan Kefarmasian di Puskesmas Kabupaten Ponorogo Norcahyanti, Ika; Hakimah, Farda; Christianty, Fransiska Maria
Journal of Islamic Pharmacy Vol 5, No 2 (2020): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v5i2.10525

Abstract

Public health center is a primary health facility, and pharmacy services support its activities. Periodic monitoring and evaluation of activities are needed to assure the quality of pharmaceutical services. Pharmacy personnels can evaluate pharmaceutical services at the public health center using a guideline published in 2008 by the Directorate of Pharmacy and Community Clinics of the Indonesian Ministry of Health. The purpose of this study was to determine the characteristics, description, and quality of pharmaceutical services at the public health centers in Ponorogo after being evaluated using a list of pharmaceutical services in 2008. This research was an observational survey on all pharmacy personnels and other personnels responsible for the pharmacy room at the public health center in Ponorogo. The analysis of data was using descriptive techniques. The results show that the public health centers were mostly an inpatient center (n=19; 61.3%) and accredited ‘madya’ (n=22; 71%). Morover, the head of a pharmacy room was dominantly a pharmacy technician (n=24; 77.4%). Pharmaceutical services generally fulfilled the supporting for and quality control indicators. However, several indicators did not fully meet the guideline, including clinical judgements, counseling, and home care. Overall, only three public health centers can be rated “good” in delivering quality pharmaceutical services, whilst the other eight and twenty were rated “moderate” and “less”, respectively.
Studi Formulasi Sediaan Lip Balm Ekstrak Kayu Secang (Caesalpinia sappan L.) dengan Variasi Beeswax Ambari, Yani; Hapsari, Fitra Nanda Dwi; Ningsih, Arista Wahyu; Nurrosyidah, Iif Hanifa; Sinaga, Butet
Journal of Islamic Pharmacy Vol 5, No 2 (2020): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v5i2.10434

Abstract

Bibir merupakan salah satu bagian kulit yang membutuhkan perlindungan agar kelembaban bibir tetap terjaga. Akibat dari fungsi perlindungan yang buruk bibir menjadi kering, pecah-pecah, dan warna bibir menjadi kusam. Lip balm adalah sediaan yang diaplikasikan pada bibir untuk mencegah bibir kering dan melindungi dari efek lingkungan yang buruk. Kualitas fisik lip balm merupakan faktor yang harus dipenuhi sebelum sediaan lip balm dipasarkan ke konsumen. Pemilihan basis yang tepat akan menentukan kualitas kekerasan sehingga dapat diterima oleh masyarakat, karena basis merupakan pembentuk utama dari sediaan lip balm. beeswax mempunyai sifat sebagai pengikat yang baik, dimana membantu untuk menghasilkan massa yang homogen. Pada penelitian ini bahan aktif yang digunakan yaitu kayu secang karena mengandung senyawa brazilein yang bisa sebagai pewarna alami dan antiokasidan.. Penelitian ini merupakan penelitian eksperimental formulasi sediaan lip balm dengan menggunakan beeswax 5%, 10% dan 15%. Tujuan penelitian ini Mengetahui formulasi yang tepat sediaan lip balm dengan bahan aktif ekstrak kayu secang (Caesalpinia sappan L.), mengetahui stabilitas fisik sediaan lip balm dengan bahan aktif ekstrak kayu secang (Caesalpinia sappan L.), mengetahui konsentrasi basis yang sesuai, untuk mendapatkan sediaan lip balm yang berkualitas (sesuai standart farmasi). Hasil penelitian telah didapatkan formula yang bagus dengan karakteristik fisik yang sesuai dengan spesifikasi yang telah ditentukan meliputi pengamatan stabilitas, pengukuran pH, pengujian homogenitas, pengujian iritasi, pengujian kesukaan (Hedonic test) dan pengujian cycling test. formula yang tepat di dapat pada formula 1 dengan konsentrasi beeswax 5% menghasilkan tekstur warna, aroma, memiliki nilai daya lekat dan daya sebar yang baik, pH sesuai terhadap pH bibir, tidak mengiritasi, sediaan homogen, paling banyak disukai oleh responden dan stabil selama penyimpanan. Konsentrasi basis yang baik yaitu basis 5% pada formula 1 karena menghasilkan tekstur lip balm semi padat dan sangat halus.  Kata kunci : Lip balm, Beeswax , Bibir, Caesalpinia sappan
Analisis Kandungan Logam Berat Cd, Hg, dan Pb Daun Semanggi (Marsilea crenata Presl.) di Desa Semen, Kecamatan Pagu, Kabupaten Kediri Ma'arif, Burhan; Muti'ah, Roihatul; Suryadinata, Arief; Nashichuddin, Ach; Karawid, Galih Elsy
Journal of Islamic Pharmacy Vol 5, No 2 (2020): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v5i2.9356

Abstract

Semanggi (Marsilea crenata Presl.) berpotensi untuk diolah menjadi produk obat herbal karena khasiat yang dimilikinya. Namun, tanaman semanggi (Marsilea crenata Presl.) memiliki kemampuan fitoremediasi sehingga berdampak pada penimbunan logam berat yang berbahaya untuk kesehatan tubuh. Penelitian ini dilakukan untuk mengetahui kandungan logam berat Cd, Hg dan Pb pada daun semanggi di Kabupaten Kediri (Desa Semen, Kecamatan Pagu) untuk dibandingkan dengan Perka BPOM No. 12 tahun 2014 terkait batas logam berat untuk simplisia. Metode yang digunakan yaitu menggunakan Atomic Absorption Spectroscopy (AAS) pada sampel simplisia daun tanaman semanggi dan juga sampel tanah sebagai pembanding. Dari hasil pengujian sampel simplisia daun semanggi di Kabupaten Kediri (Desa Semen, Kecamatan Pagu) terdapat (Cd) dengan kadar 4,16 ppm. Hasil ini menunjukkan tidak memenuhi standar Perka BPOM No. 12 tahun 2014 karena melewati batas minimum Cd sebesar ≤ 0,3 ppm.
Analisis Efektivitas Biaya Seftriakson dan Sefotaksim pada Pasien Demam Tifoid Anak di Instalasi Rawat Inap Shofa dan Marwah PKU Karangasem Muhammadiyah Paciran Tahun 2019 Hidayah, Shofi Nurul; Hakim, Abdul; Syahrir, Ach; Anggraini, Wirda
Journal of Islamic Pharmacy Vol 5, No 2 (2020): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v5i2.9819

Abstract

Demam tifoid adalah suatu penyakit infeksi yang disebabkan oleh bakteri gram negatif Salmonella typhi. Pengobatan untuk demam tifoid berupa terapi simtomatik dan terapi antibiotik. Cost-effectiveness Analysis (CEA) adalah salah satu pendekatan farmakoekonomi untuk mengetahui perbandingan efektivitas hasil terapi dan biaya dari beberapa alternative terapi yang digunakan. Tujuan dari penelitian ini adalah untuk menganalisis efektivitas biaya terapi penggunaan antibiotik pada pasien demam tifoid anak secara farmakoekonomi dengan pendekatan analisis efektivitas biaya di Instalasi Rawat Inap PKU Karangasem Muhammadiyah Paciran dan untuk mengetahui terapi antibiotik yang paling cost-effective. Penelitian ini merupakan penelitian deskriptif yang bersifat observasional dengan pengambilan data secara retrospektif. Data diambil dari rekam medis pasien rawat inap demam tifoid anak di PKU Karangasem Muhammmadiyah Paciran tahun 2019. Parameter yang digunakan adalah lama rawat inap, waktu bebas demam, dan total biaya medis langsung yang meliputi biaya obat, biaya alat kesehatan, biaya rawat inap, biaya laboratorium, dan biaya dokter. Pasien yang sesuai dengan kriteria inklusi dan eksklusi berjumlah 29 pasien. Antibiotik yang digunakan adalah Seftriakson dan Sefotaksim. Efektivitas biaya dinyatakan dalam ACER (Average Cost Effectiveness Ratio) yang diperoleh dari rerata total biaya medis langsung dibagi dengan rerata outcome klinis. Nilai ACER dari antibiotik Seftriakson Rp.346.357,04/hari untuk lama rawat inap dan Rp.447.853,61/hari untuk lama waktu bebas demam, dan Sefotaksim Rp.390.452,88/hari untuk lama rawat inap dan Rp.489.655,89/hari untuk lama waktu bebas demam. Kesimpulan dari penelitian ini adalah bahwa antibiotik yang paling cost-effective yaitu Seftriakson.
Formulasi dan Evaluasi Lotion Ekstrak Alpukat (Persea Americana) sebagai Pelembab Kulit Iskandar, Benni; Sidabutar, Santa Eni BR; Leny, Leny
Journal of Islamic Pharmacy Vol 6, No 1 (2021): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v6i1.11822

Abstract

Avocado (Persea americana) contains a lot of vitamin A, vitamin B, vitamin C and vitamin E which is good to be used in skin care. One of the cosmetics for skincare is lotion, which is a liquid emulsion consisting of oil phase and water phase stabilized by emulgator. Lotion is used to protect and maintain skin moisture level. The purpose of this research was to formulate and evaluate the lotion in order to assure the physical characteristic and stability were accepted according to the Handbook of Pharmaceutical Excipients and Indonesia Pharmacopeia requirements.Formulation were made by using these following ingredients: glyceryl monostearate, cera alba, tween 80, glycerin, liquid paraffin, benzyl alcohol, perfume, aquadest. The study used 2 variation of concentration, which is  0.5% and 1% avocado extract as active substance, besides there is variations in glyceryl monostearate (5.5% and 5.7%), cera alba (2.7% and 2.9%), tween 80 (3.5% and 3.7%), glycerin (10% and 12%), liquid paraffin (10% and 12%), and benzyl alcohol (0.15% and 0.17%) in formulations I and II. Lotion was then tested for its physical properties, which include organoleptic test, homogeneity test, pH test, and spreadability test, lastly hedonic and irritation test were also being examined.Based on the results of physical properties test, both lotion formulations showed a viscous texture, beige and dark beige color with a distinctive odor, homogeneous, not irritating, have a pH value in the range of 4.55-5.31 with 4.9-5.15 cm spread. In the hedonic test on 10 panelists, lotion I formulation gave the most satisfaction score and comforty from respondents. Respondent's satisfaction on the appearance comprise the texture, color, and odor. Besides, viscosity and spreadability were also marked as how comfort the lotion is when it was applied to the respondent’s skin.Keywords :  Avocado, Extract, Lotion, Cosmetic, Moisturizer
Techniques for Reducing Iron (Fe) Content in Groundwater: an Article Review Yazid, Edy Agustian; Wafi, Abdul; Saraswati, Arina
Journal of Islamic Pharmacy Vol 6, No 1 (2021): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v6i1.12078

Abstract

Iron is a chemical element that is found in almost every place on earth, including in well water or groundwater. Iron can be suspended in water with organic substances or inorganic solids in the form of ferrous cations (Fe2+) and ferries (Fe3+). The presence of iron that exceeds the threshold can cause detrimental effects such as corrosion of the piping, the color of the water turns brown, smells bad, and can cause health problems. The iron content in groundwater can be reduced so that it can be used as water that is fit for consumption or use in everyday life. This study aims to determine several types of techniques used to reduce iron in groundwater or well water through literature studies. Techniques covered include filtration, aeration, adsorption, coagulation, electrocoagulation, and cascade aerators. The results showed that the greatest reduction in efficiency was found in the combination type of adsorption technique and filtration technique by more than 99.1%, then followed by the electrocoagulation technique of  99.74%. From all the techniques studied in this study, it can be concluded that all techniques can reduce iron levels in which the combination of adsorption and filtration techniques is the most effective.Keywords: Technique, reduction, iron content, groundwater
Karakterisasi Sistem Dispersi Padat Meloksikam Dengan Matriks PEG 6000 Dan Poloxamer 188 Dibuat Dengan Menggunakan Metode Peleburan Najih, Yuli Ainun; Nailufa, Yuyun; Rakhma, Dita Nurlita; Widjaja, Bambang; Silviyah, Lailatul; Mujahida, Choirun
Journal of Islamic Pharmacy Vol 6, No 1 (2021): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v6i1.11284

Abstract

Meloxicam is included in the class II Biopharmaceutical Classification System (BCS). This drug has low solubility and high permeability. The solubility is one of the factors that affect in the dissolution rate of drug. One of the effort to increase dissolution of meloxicam is by forming a solid dispersion system made using melting method. The addition of PEG 6000 and poloxamer 188 carriers determine in the solid dispersion system aims to increase the dissolution rate of meloxicam. The purpose of this study is to characterize the meloxicam solid dispersion system with PEG 6000 and poloxamer 188 matrices at a ratio of 99:1 and 98:2 made by the melting method when compared with the physical mixture and its pure compound using Powder X-Ray Diffaction, DSC and FTIR. The results of meloxicam solid dispersion with a ratio 99:1 and 98:2 showed the disappearance of the typical peak of meloxicam at an angel of 2θ 6.5° and 11.2°. The thermogram data using DSC shows a decrease in melting point of solid dispersion system with a ratio of 99:1 and 98:2 namely 64.33°C and 64.21°C. The result of the characterization of meloxicam solid dispersion with FTIR showed that the identified spectrum were in the spectrum range of meloxicam, PEG 6000, poloxamer 188 indicating there was no incteraction in the meloxicam solid dispersion system.Keywords: Meloxicam, PEG 6000, Poloxamer 188, Solid Dispersion, Melting Method, Characterization

Page 6 of 16 | Total Record : 156

 4   5   6   7   8 

Filter by Year

2015 2025


Reset
Filter By Issues
All Issue Vol 10, No 1 (2025): J. Islamic Pharm. Vol 9, No 2 (2024): J. Islamic Pharm. Vol 9, No 1 (2024): J. Islamic Pharm. Vol 8, No 2 (2023): J. Islamic Pharm. Vol 8, No 1 (2023): J. Islamic Pharm. Vol 7, No 2 (2022): J. Islamic. Pharm. Vol 7, No 1 (2022): J. Islamic Pharm. Vol 6, No 2 (2021): J. Islamic Pharm. Vol 6, No 1 (2021): J. Islamic Pharm. Vol 5, No 2 (2020): J. Islamic Pharm. Vol 5, No 1 (2020): J. Islamic Pharm. Vol 4, No 2 (2019): J. Islamic Pharm. Vol 4, No 1 (2019): J. Islamic Pharm. Vol 3, No 2 (2018): J. Islamic Pharm. Vol 3, No 1 (2018): J. Islamic Pharm. Vol 2, No 2 (2017): J. Islamic Pharm. Vol 2, No 1 (2017): J. Islamic Pharm. Vol 1, No 1 (2016): J. Islamic Pharm. Vol 1, No 1 (2015): Jurnal Farmasains More Issue