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Perbandingan Aktivitas Antibakteri Ekstrak Bawang Tiwai (Eleutherine palmifolia (L.) Merr) dengan Pelarut Etil Asetat dan Etanol terhadap Pertumbuhan Bakteri Enterococcus faecalis Penyebab Infeksi Saluran Akar: Comparison of Antibacterial Activity of Tiwai Onion Extract (Eleutherine palmifolia (L.) Merr) with Ethyl Acetate and Ethanol Solvents Against the Growth of Enterococcus faecalis Bacteria Causing Root Canal Infection Samiaji, Airvin Wika; Yani, Sinar; Astuti, Lilies Anggarwati; Anitasari, Silvia; Yadi, Yadi
Jurnal Sains dan Kesehatan Vol. 7 No. 1 (2025): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v7i1.2363

Abstract

Pulp infection is capable of causing pulpitis, an inflammatory condition. Tiwai onion is known for its antibacterial properties. Compare the antibacterial activity of tiwai onion (Eleutherine palmifolia (L.) Merr) extract using ethyl acetate and ethanol solvents against Enterococcus faecalis bacteria causing root canal infection. Onion tiwai extract was prepared by maceration method using ethyl acetate and ethanol solvents. Activity test was determined by liquid and solid dilution method. In liquid dilution, there was no bacterial growth in ethyl acetate and ethanol extracts with a concentration of 20mg/ml. In the solid dilution test, the extract with ethyl acetate solvent showed a value of 20mg/ml, which means bactericidal. However, the ethanol solvent extract showed bacterial growth at a concentration of 20mg/ml, meaning it was not bactericidal. Onion tiwai  extracts with ethyl acetate and ethanol solvents showed different antibacterial activities against Enterococcus faecalis. Only extracts with ethyl acetate solvent showed bactericidal properties Keywords:          Eleutherine palmifolia (L) Merr, Enterococcus faecalis, ethanol, ethyl acetate, Pulpitis   Abstrak Infeksi pulpa mampu menyebabkan pulpitis, suatu kondisi peradangan. Bawang tiwai dikenal karena sifat antibakterinya. Tujuan penelitian ini adalah untuk membandingkan aktivitas antibakteri ekstrak bawang tiwai (Eleutherine palmifolia (L.) Merr) memakai pelarut etil asetat dan etanol terhadap bakteri Enterococcus faecalis penyebab infeksi saluran akar. Ekstrak bawang tiwai dibuat melewati metode maserasi dengan memakai pelarut etil asetat dan etanol. Uji aktivitas ditentukan dengan metode pengenceran cair dan metode pengenceran padat. Penelitian ini diperoleh hasil bahwa pada pengenceran cair, tak ada pertumbuhan bakteri pada ekstrak etil asetat dan etanol dengan konsentrasi 20mg/ml. Dalam uji pengenceran padat, ekstrak dengan pelarut etil asetat memperlihatkan nilai 20mg/ml, yang artinya bersifat bakterisidal. Namun, ekstrak dengan pelarut etanol memperlihatkan pertumbuhan bakteri pada konsentrasi 20mg/ml, artinya tidak bersifat bakterisidal. Ekstrak bawang tiwai (Eleutherine palmifolia (L.) Merr) dengan pelarut etil asetat dan etanol memperlihatkan aktivitas antibakteri yang berbeda terhadap Enterococcus faecalis. Hanya ekstrak dengan pelarut etil asetat yang memperlihatkan sifat bakterisidal. Kata Kunci:         Eleutherine palmifolia (L) Merr, Enterococcus faecalis, Etanol, Etil asetat, Pulpitis
Aktivitas Ekstrak Bawang Tiwai (Eleutherine palmifolia (L.) Merr) Dengan Pelarut Etil Asetat Sebagai Alternatif Antibakteri Terhadap Pertumbuhan Bakteri Enterococcus faecalis Penyebab Infeksi Saluran Akar Samiaji, Airvin Wika; Sinar, Yani; Astuti, Lilies Anggarwati; Silvia, Anitasari; Yadi, Yadi
Sinnun Maxillofacial Journal Vol. 7 No. 01 (2025): April 2025
Publisher : Fakultas Kedokteran Gigi Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/smj.v7i01.144

Abstract

Pendahuluan: Infeksi pulpa dapat mengakibatkan pulpitis, jika tidak ditangani, kondisi ini dapat mengarah pada penyakit nekrosis pulpa. Masyarakat indonesia mengenal tradisi penggunaan tanaman sebagai pengobatan tradisional, contohnya seperti bawang tiwai. Bawang tiwai memiliki kelebihan dengan aktivitas kandungannya sebagai antiinflamasi, antikanker, antidiabetes, antivirus antihipertensi dan antibakteri. Tujuan: untuk mengetahui aktivitas ekstrak bawang tiwai (Eleutherine palmifolia (L.) Merr) dengan pelarut etil asetat sebagai alternatif antibakteri terhadap pertumbuhan bakteri Enterococcus faecalis penyebab infeksi saluran akar. Metode: Ekstrak bawang tiwai dibuat dengan pelarut etil asetat menggunakan metode maserasi lalu dilakukan serial dilusi hingga diperoleh berbagai konsentrasi. Uji aktivitas diukur menggunakan metode mikrodilusi cair dan metode mikrodilusi padat lalu diinkubasi. Hasil: Pada dilusi cair menunjukkan nilai 20 mg/ml dan pada uji dilusi padat yaitu 20 mg/ml. Kesimpulan: Ekstrak bawang tiwai (Eleutherine palmifolia) (L) Merr) dengan pelarut etil asetat pada konsentrasi 20 mg/ml dapat digunakan sebagai alternatif antibakteri karena memiliki sifat membunuh bakteri (bakterisidal).
Pemanfaatan dan Pelestarian Hutan Mangrove di Desa Koepisino Kecamatan Bonegunu Kabupaten Buton Utara Yadi, Yadi; Marhadi, Akhmad; Rahman, Abdul
JURNAL KABANTI: Kerabat Antropologi Vol 9 No 1 (2025): Volume 9, Nomor 1, Juni 2025
Publisher : Jurusan Antropologi Fakultas Ilmu Budaya Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33772/s75rhm50

Abstract

This research aims to find out and describe the benefits of mangrove forests in Koepisino Village, Bonegunu District, North Buton Regency and the efforts of the community and government in preserving mangrove forests in Koepisino Village, Bonegunu District, North Buton Regency. This research method uses a qualitative descriptive research method. The data collection techniques used in this research are observation, interviews and documentation methods. The theory used is Cultural Ecology Theory by Julian H Steward. The results of this research show that mangrove wood is very useful for the people of Koepisino village, one of which is as a tool for building houses, such as house frames, rafters and boards, apart from being useful for building houses, it is also used as firewood, slanted poles and para-para for drying jelly. . The Koepisino Village community also conserves mangrove forests together with the local government, the community looks for mangrove wood seeds, plants and controls the growth of the mangrove plants that have been planted, while the government only provides a budget for preservation and supervises the community who carry out the planting.
Analysis of Factors Related to the Incidence of Ventilator-Associated Pneumonia (VAP) in the Intensive Care Unit Cahyana, Yudi Jaya; Pakki, Irfansyah Baharuddin; Lestari, Ida Ayu Indira Dwika; Adrianto, Ratno; Yadi, Yadi; Azmiardi, Akhmad
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.6628

Abstract

Ventilator-associated pneumonia (VAP) occurs in patients who have been on mechanical ventilation with an endotracheal tube (ETT) for at least 48 hours. This type of pneumonia typically arises as a result of nosocomial infections or Healthcare-Associated Infections (HAIs) and is commonly linked to the use of ventilators in hospital settings. This study was to identify the factors associated with the incidence of VAP among patients admitted to the Intensive Care Unit of Abdoel Wahab Sjahranie Hospital, Samarinda. Method: A cross-sectional study was conducted. The study population consisted of all patients who had undergone mechanical ventilation in the ICU without a prior history of pneumonia, totaling 118 respondents, using the HAIs bundle observation tool and direct observation. Chi-square and multiple logistic regression were used for statistical analysis, along with a predictive model. The results showed that the prevalence of VAP among respondents in the ICU was 5.9%. Factors significantly associated with the incidence of VAP included duration of ventilator use (p = 0.000), oral hygiene procedures (p = 0.000), head-of-bed elevation to 30–45° (p = 0.007), hand hygiene compliance (p = 0.015), and aseptic suctioning procedures (p = 0.043). The multivariate analysis identified duration of ventilator use ≥96 hours as the most dominant factor, with the highest Odds Ratio (OR = 13.975; 95% CI: 0.753–227.435). Duration of ventilator use was the most significant factor associated with an increased risk of VAP, with patients ventilated for ≥96 hours being 13 times more likely to develop VAP compared to those ventilated for <96 hours. Proper oral hygiene, appropriate head-of-bed elevation (30–45°), compliance with hand hygiene, and aseptic suctioning procedures were also found to be significantly associated with VAP incidence among ICU patients at Abdoel Wahab Sjahranie Hospital
The Relationship Between Lipid Profile and HBA1C Levels in Type 2 Diabetes Melitus Patients Pasinggi, Miako; Pakki, Irfansyah Baharuddin; Yadi, Yadi
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.6629

Abstract

Diabetes Mellitus is a chronic disease with high morbidity and mortality rates, requiring comprehensive and integrated management. Dyslipidemia is an important risk factor contributing to the occurrence of both microvascular and macrovascular complications in individuals with Diabetes Mellitus. Optimal control of HbA1c levels and lipid profiles is considered essential in reducing the risk of complications and improving patient outcomes. Therefore, monitoring and managing these parameters is a critical component of diabetes care to prevent further complications. This study aims to analyze relationship between lipid profile with HbA1c levels in Type 2 Diabetes Mellitus (T2DM) patients at Puskesmas in Samarinda. A cross-sectional study was conducted involving 1,482 patients with T2DM, selected through a total sampling technique. Data were obtained from secondary sources, specifically medical records. Bivariat analysis using the Chi-Square test was performed to evaluate the relationship between lipid profile and HbA1c levels. The analysis identified significant relationship between TG (p = <0,001 ; OR = 3,350; 95% CI:2,701-4,157), TC (p = <0,001; OR = 1,862; 95% CI: 1,486-2,334), HDL-C (p = 0,003; OR = 1,567; 95% CI: 1,169-2,100), and LDL-C (p = 0,013; OR = 1,310; 95% CI: 1,063-1,614). This study found a significant association between all components of the lipid profile and HbA1c levels among patients with type 2 diabetes mellitus (T2DM) in Samarinda. Levels of triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were all significantly related to poor glycemic control. .
Analysis of Factors Affecting Antiretroviral Adherence in HIV/AIDS Patients Makin, Mochamad; Pakki, Irfansyah Baharuddin; Azmiardi, Akhmad; Adrianto, Ratno; Yadi, Yadi; Lestari, Ida Ayu Indira Dwika
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.6944

Abstract

Human Immunodeficiency Virus (HIV) remains a major global public health issue, with antiretroviral (ARV) therapy playing a critical role in its management. Adherence to ARV therapy is essential to suppress viral load, prevent drug resistance, and improve the quality of life of people living with HIV/AIDS (PLWHA). However, cases of non-adherence persist. At RSUD A. Wahab Sjahranie, a referral hospital in East Kalimantan, 16% of patients have been found to be non-adherent to their ARV medication. Ensuring adherence is vital to avoid complications and prevent HIV transmission. This study aims to identify and analyze the factors influencing ARV adherence among HIV/AIDS patients at the Anyelir Outpatient Clinic, RSUD A.W. Sjahranie, Samarinda. This study employed a quantitative analytical approach with a cross-sectional design. It involved 106 HIV/AIDS patients who were actively receiving antiretroviral therapy (ART). The independent variables included knowledge, self-efficacy, duration of therapy, side effects, family support, social support, and healthcare staff attitude. Data were collected using a structured questionnaire administered directly to respondents and supported by secondary data from medical records. A total sampling technique was applied, and data were analyzed using chi-square tests and logistic regression at a 95% significance level. A total of 85.8% of respondents were classified as adherent to ARV treatment. Bivariate analysis showed that knowledge (p = 0.019), family support (p = 0.018), social support (p = 0.011), healthcare staff attitude (p = 0.006), and self-efficacy (p = 0.002) were significantly associated with ARV adherence. Multivariate analysis identified family support (OR = 4.275), healthcare staff attitude (OR = 6.834), and self-efficacy (OR = 20.241) as the most influential factors. Knowledge, side effects, family support, social support, healthcare staff attitude, and self-efficacy are significant determinants of ARV adherence among PLWHA. Among these, self-efficacy emerged as the most dominant factor.
Effect of Eleutherine bulbosa Tiwai Onion Oil as an antimicrobial hastati, Sri; Yuniati, Yuniati; Yadi, Yadi; ismail , Sjarief
Mulawarman International Conference on Tropical Public Health Vol. 1 No. 1 (2025): The 3rd MICTOPH
Publisher : Faculty of Public Health Mulawarman University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background : East Kalimantan as a tropical rain forest area has biodiversity. One of them that has been used by the traditional community is Dayak onion or Tiwai onion (Eleutherine bulbosa Mill Urb). Tiwai onion has many proven properties for traditional medicine in the treatment of diseases such as diabetes, heart disease, dysentery, colitis, laxative for urination and defecation, anti-vomiting, anti-inflammatory, anti-bleeding, anti-fertility, ulcer or skin diseases, Dayak onions have phytochemical components such as flavonoids, phenols and alkaloids as well as terpenes-steroids. Terpenoids have soluble properties in organic solvents such as alcohol and ether. Objective : The aim of this study was to determine the effect of tiwai onion oil as an antimicrobial in vitro. Tiwai Onion Oil is made by mixing Tiwai Onion Extract with Virgin Coconut Oil (VCO). Research Methods/ Implementation Methods : The research method used is true experimental with a posttest-only control group design. Antimicrobial test with microdilution method. Results : The results of this study showed that Eleutherine bulbosa (Mill) Urb Tiwai Onion Oil had an antimicrobial effect on Staphylococcus aureus ( konsentration 50 μL) and Escherichia coli konsentration (25 μL and 50 μL) Conclusion/Lesson Learned : Eleutherine bulbosa (Mill) Urb Tiwai Onion Oil had an antimicrobial effect on Staphylococcus aureus ) and Escherichia coli
Tren dan Tantangan Transformasi Digital pada UMKM: Systematic Literatur Review Masitoh, Gustina; Yadi, Yadi; Rohmah, Miftakhur; Carolina, Debi; Azmiyati, Afifah
Kompak :Jurnal Ilmiah Komputerisasi Akuntansi Vol. 18 No. 2 (2025): Kompak : Jurnal Ilmiah Komputerisasi Akuntansi
Publisher : Universitas Sains dan Teknologi Komputer

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51903/kompak.v18i2.2872

Abstract

Digital transformation has become a crucial requirement for Micro, Small, and Medium Enterprises (MSMEs) to enhance their competitiveness in the technological era. This study aims to examine the trends and challenges faced by MSMEs in the digitalization process through a systematic literature review (SLR) approach. A total of 35 scholarly articles published within the last five years were analyzed using specific inclusion and exclusion criteria. The findings indicate that the digitalization trends among MSMEs encompass the adoption of cloud-based technologies, the use of social media for marketing, the utilization of e-commerce platforms, and the integration of digital financial systems. However, the main challenges identified include low digital literacy, limited infrastructure, relatively high implementation costs, resistance to change, and insufficient policy support. This study not only provides a comprehensive understanding of the current state of MSME digital transformation but also identifies research gaps that have been rarely discussed. Furthermore, it offers strategic directions for researchers, MSME practitioners, and policymakers to develop more targeted strategies in accelerating and expanding digital transformation within Indonesia’s MSME sector.
Uji Aktivitas Antibakteri Ekstrak Tiga Tumbuhan Obat Indonesia Terhadap Pertumbuhan Streptococcus mutans: Antibacterial Activity Testing From The of Extract of Three Indonesian Medicinal Plants on Streptococcus mutans Growth Dewi, Asri Puspita; Pramasari, Cristiani Nadya; Ismail, Sjarif; Yani, Sinar; Yadi, Yadi
Jurnal Sains dan Kesehatan Vol. 6 No. 4 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i4.2361

Abstract

Three common plant species in Indonesia, particularly on the island of Kalimantan, are Mahang leaves (Macaranga motleyana), dahu leaves (Dracontomelon dao), and Dayak onion tuber (Eleuthrine palmifolia Merr). These plants exhibit antibacterial effects on both aerobic and anaerobic bacteria, but their impact on the growth of Streptococcus mutans, the bacteria responsible for causing dental cavities, is currently unknown. The aim of this research is to assess the antibacterial properties of extracts from three plants on the growth of Streptococcus mutans bacteria. This study is a true experimental research with a post-test only control group design. The three samples were immersed in ethanol to extract their components, and the testing of the extracts was done using the microdilution method. The Minimum Inhibitory Concentration (MIC) of Mahang leaf extract (Macaranga motleyana) was 6.25 mg/mL, and for dahu leaf extract (Dracontomelon dao), it was 12.5 mg/mL. The Dayak onion tuber extract (Eleuthrine palmifolia Merr) did not exhibit any antibacterial activity at concentrations ranging from 25 mg/mL to 1.5625 mg/mL. The ethanol extract of Macaranga motleyana exhibits greater inhibition of Streptococcus mutans growth compared to another plants. Keywords:          Macaranga motleyana, Dracontomelon dao, Eleuthrine palmifolia Merr, Streptococcus mutans, Antibacterial   Abstrak Daun mahang (Macaranga motleyana), daun dahu (Dracontomelon dao), dan umbi bawang dayak (Eleuthrine palmifolia Merr) merupakan tanaman yang banyak ditemui di Indonesia khususnya di pulau Kalimantan. Ketiga tumbuhan tersebut telah diketahui memiliki aktivitas antibakteri yang bersifat aerob dan anaerob, tetapi belum diketahui aktivitas terhadap pertumbuhan bakteri Streptococcus mutans penyebab karies gigi. Tujuan penelitian ini adalah untuk mengetahui aktivitas antibakteri pada ekstrak ketiga tumbuhan tersebut terhadap Streptococcus mutans. Penelitian ini merupakan jenis penelitian eksperimental murni dengan desain penelitian post test only control group. Ketiga ekstrak dimaserasi menggunakan etanol dan diuji dengan metode mikrodilusi. Pada penelitian didapatkan minimum inhibitory concentration dari ekstrak mahang (Macaranga motleyana) 6,25 mg/mL dan 12,5 mg/mL untuk ekstrak dahu (Dracontomelon dao). Ekstrak umbi bawang dayak (Eleuthrine palmifolia Merr) tidak memperlihatkan hambatan pertumbuhan bakteri pada berbagai konsentrasi yang diujikan. Ekstrak daun mahang (Macaranga motleyana) memiliki kemampuan menghambat pertumbuhan bakteri Streptococcus mutans lebih kuat dibandingkan dengan ekstrak tumbuhan yang lain. Kata Kunci:         Macaranga motleyana, Dracontomelon dao, Eleuthrine palmifolia Merr, Streptococcus mutans, Antibakteri
Optimization of Interactive Multimedia to Enhance Students’ Cognitive Development through Islamic Religious Education Liana, Disti; Novianty, Melisa; Efan, Efan; Yadi, Yadi
FINGER : Jurnal Ilmiah Teknologi Pendidikan Vol. 4 No. 3 (2025): Finger : Jurnal Ilmiah Teknologi Pendidikan November 2025
Publisher : CV. Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/finger.v4i3.535

Abstract

Background: Islamic Religious Education (IRE) plays a crucial role in shaping students’ character at the elementary level. However, traditional learning methods often limit student engagement and independent learning.Aims: This study aims to develop and validate interactive multimedia for IRE aligned with the Merdeka Curriculum, focusing on cognitive enhancement and Islamic character formation.Method: The study employed a Research and Development (R&D) approach using the ADDIE model (Analysis, Design, Development, Implementation, and Evaluation). Participants included 30 upper-grade elementary students and 5 IRE teachers. Instruments consisted of expert validation rubrics (content, usability, benefit, and technical aspects) and practicality questionnaires. Content validity was analyzed using Aiken’s V, while reliability was measured with Cronbach’s alpha. Ethical clearance and consent from participants were obtained.Results: The multimedia was validated by experts with an average Aiken’s V of 0.87 (valid) and practicality rated by teachers and students with a Cronbach’s α of 0.89 (good reliability). The average practicality percentage reached 85.75%, categorized as very practical. Annotated screenshots show labeled UI features such as transliteration toggles, audio controls, and navigation bars, supporting accessibility and engagement.Conclusion: The developed multimedia has been validated and proven practical for classroom use. While findings confirm feasibility and usability, its effectiveness in improving learning outcomes requires further experimental testing.