Article Per Year (5 Year)
p-Index From 2020 - 2025
2.617
P-Index
This Author published in this journals
All Journal Indonesian Journal of Pharmaceutical Science and Technology Biology, Medicine, & Natural Product Chemistry Jurnal Kedokteran Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Biologi Tropis JSFK (Jurnal Sains Farmasi & Klinis) JURNAL PENDIDIKAN TAMBUSAI Jurnal Gema Ngabdi Jurnal Pengabdian Masyarakat Sains Indonesia (Indonesian Journal Of Science Community Services) Jurnal Abdi Insani Jurnal Kesehatan Tambusai Sasambo Journal of Pharmacy Jurnal Pepadu Innovative: Journal Of Social Science Research Jurnal Sains dan Kesehatan
Aini, Siti Rahmatul
Unknown Affiliation
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

Published : 21 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : Biology, Medicine,

 1 
In Vitro Mucolytic Activity of Cardamom Fruit (Amomum compactum) Decoction on Duck Egg Albumens Vitri, Desy Aryanti Pardilla; Aini, Siti Rahmatul; Saputri, Legis Ocktaviana
Biology, Medicine, & Natural Product Chemistry Vol 13, No 2 (2024)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2024.132.541-547

Abstract

Cardamom (Amomum compactum) is empirically used as a cough medicine by using its seeds and fruits. Cardamom seeds have been shown to have mucolytic activity at a concentration of 0.8%, while cardamom fruit has not been studied. This study aimed to determine the mucolytic activity of cardamom fruit decoction at variation concentrations. Mucolytic activity tests were carried out in vitro on duck egg albumens at 3%, 6%, and 12% variation concentrations of cardamom fruit decoction. N-acetylcysteine 0.1% was positive control, while phosphate buffer and Tween 80 were negative controls. The mucolytic activity was determined based on the viscosity value measured by flow time using an Ostwald viscometer and density measurement using a pycnometer. Data from each group were analyzed using SPSS with parametric One-Way ANOVA and Post Hoc tests. The results showed that cardamom fruit decoction at concentrations of 3%, 6%, and 12% had values that were not significantly different from N-acetylcysteine (p>0.05) and there was no significant difference (p>0.05) between each concentration group. Accordingly, the research concludes that cardamom fruit decoction at concentrations of 3%, 6%, and 12% has mucolytic activity comparable to N-acetylcysteine.
Anti –Inflammatory Activity of Propolis Trigona sp. Water Extract from North Lombok with Red Blood Cell Membrane Stability Method Humaira, Ani Fatin; Aini, Siti Rahmatul; Hasina, Raisya
Biology, Medicine, & Natural Product Chemistry Vol 13, No 2 (2024)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2024.132.555-558

Abstract

Propolis is a bee product that can be used as an anti-inflammatory. Cultivation of propolis-producing bees is also carried out in North Lombok. However, propolis has not been utilized optimally by the people of North Lombok. Apart from that, testing of North Lombok propolis is still limited to the chemical content and antioxidant activity of propolis extracted with ethanol solvent. Therefore, this study aims to determine the activity and effective concentration of North Lombok propolis water extract as an anti-inflammatory using the red blood cell membrane stability method. Groups include control groups such as positive control (diclofenac sodium), negative control (distilled water), and test groups (propolis water extract concentrations of 10%, 12.5%, 15%, 17.5%, 20%, 22.5%, 25%, 27.5%, and 30%). In The first step human blood was centrifuged of human blood, and then part of the red blood cells (sediment) was taken and saline was added to obtain a red blood cell suspension. Next, mixing the test solution was carried out in the order of 0.5 ml of red blood cell suspension, then 0.5 ml of extract was added (0.1% w/v Na-diclofenac solution in the positive control, distilled water in the negative control), 1 mL of buffer solution and 2 mL of hyposaline solution, then homogenized. Each group was incubated at 37°C for 30 minutes, then centrifuged for 10 minutes at 3000 rpm. The supernatant was taken, and the absorbance was read with a UV-Vis spectrophotometer at 560 nm. Next, the percentage value of red blood cell hemolysis protection was calculated. The data obtained were tested statistically using One-way ANOVA and post-hoc (LSD) tests SPSS version 29. The results showed that propolis water extract concentrations were 10%, 12.5%, 15%, 17.5%, 20%, 22.5%, 25%, 27.5%, and 30% have anti-inflammatory activity because they can increase the stability of the red blood cell membrane with a percentage of hemolysis protection of respectively 57.92%, 59.99%, 60.99%, 61.99%, 64.31%, 69.59%, 75.07%, 79.77% and 84.45%. Propolis water extract concentrations of 10%, 12.5%, 15%, 17.5%, 20%, 22.5%, and 25% had anti-inflammatory effects that were not significantly different from the positive control (p>0.05). The 27.5 % and 30% concentrations had a higher percent hemolysis protection value than the positive control (p<0.05).
Co-Authors Adinda, Putri Adira, Nindia Oktaviani Agustini, Nur Indah Ain, Nisrina Huurul Alamanda, Baiq Irzana Putri Alfiyandhini, Elya Nanda Ananta, Muhammad Naufal Farras Apriliani, Baiq Dian Ariani, Fitri Arzaqi, Yazid Maula Ashri, Julita Mizwaratussyifaul aurelia, laili Candra Eka Puspitasari Doo, Viona Febyola Refana Fardiaz, Muhammad Abdurrahman Fitri, Baiq Anisa Fitriana, Nur Fadila Hamdin, Candra Dwipayana Hasina, Raisya Hidayat, Lalu Husnul Hidayati, Agriana Rosmalina Humaira, Ani Fatin Inggit, Baiq Putri Maharani Bine Khalil, Luthfi Riza Lestari, Dian Fathita Dwi Lisnasari, Baiq Risky Wahyu Loga, Sakdiana Maghfirahandini, Reivirly Khairadaty Mahacita Andanalusia Mardiyah, Raudatul Ni Made Amelia Ratnata Dewi Nirmala, Annisa Rizka Nugrahani, Baiq Dwiyan Nuralyza, Imasayu Nurhidayah, Afifah Nurhidayati Nurhidayati Ocktaviana Saputri, Legis Praditama, Lalu Denendra Pratama, Iman Surya Pujiarohman, Pujiarohman Putri, Dhea Rizma Demula Putri, Dheden Nurhani Bija Rahim, Adelia Riezka Rahmatullah, Lalu Mas’ud RISMIYATI RISMIYATI Salsabiella, Baiq Rani Saputra, Yoga Dwi Sari, Meutia Yusnita Sausan, Salwa Setiawan, Wahyu Aldi Siti Fatmah, Siti Solehah, Kurnia Sunarwidhi, Anggit Listyacahyani Ulya, Tuhfatul Utari, Weny Syafitri Utari, Widi Gustita Vitri, Desy Aryanti Pardilla Yayuk Andayani Yazid Maula