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All Journal Bioeducation Journal Jurnal Pelita Pendidikan Jurnal Prestasi Olahraga Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Biosfer: Jurnal Tadris Biologi Indonesian Journal of Cancer Chemoprevention Jurnal Penelitian Pendidikan IPA (JPPIPA) JPBIO (Jurnal Pendidikan Biologi) IJoASER (International Journal on Advanced Science, Education, and Religion) Bioedusiana: Jurnal Pendidikan Biologi Sainstek : Jurnal Sains dan Teknologi Journal of Law and Policy Transformation Spizaetus: Jurnal Biologi dan Pendidikan Biologi LOSARI: Jurnal Pengabdian Kepada Masyarakat Jurnal Ilmiah Wahana Pendidikan Sinar Sang Surya: Jurnal Pusat Pengabdian kepada Masyarakat El-Mujtama: Jurnal Pengabdian Masyarakat EduInovasi: Journal of Basic Educational Studies Jurnal Pengabdian Masyarakat Aufa (JPMA) Jurnal Pengabdian Masyarakat : Pemberdayaan, Inovasi dan Perubahan Jurnal Al-Qiyam Jurnal Tana Mana Journal of Engineering and Information Technology for Community Service International Journal of Advanced Multidisciplinary Biocaster : Jurnal Kajian Biologi Journal of Food and Agricultural Product Communication and Information Journal El-Mujtama: Jurnal Pengabdian Masyarakat EduInovasi: Journal of Basic Educational Studies
HARTONO, ADI
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In Silico Study of Chemical Compounds in Plantago major L. as Anti-Androgen Baihaqi, Achmad Al; Isman, Hasna Siti Munifah; Fauziyyah, Ganis Fitria; Hutabarat, Rismauli Ruth Natasari; Hartono, Adi; Megantara, Sandra
Indonesian Journal of Cancer Chemoprevention Vol 13, No 1 (2022)
Publisher : Indonesian Society for Cancer Chemoprevention

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14499/indonesianjcanchemoprev13iss1pp33-45

Abstract

Prostate cancer is the most common type of cancer diagnosed in men worldwide and the second leading cause of death after lung cancer. Testosterone and dihydrotestosterone (DHT) have been known to play an essential role in prostate cancer. Androgen receptor (AR) binding to the ligand allows homodimerization and translocation to the nucleus, which acts as a transcription factor for androgen-responsive genes such as PSA (Prostate-specific antigen). Although many anti-androgens have been established, including Bicalutamide, Flutamide, and Abiraterone, the problem of non-specific cytotoxicity effects and cancer recurrence due to potential drug resistance remains a significant obstacle to establishing effective therapy. Plantago major L. is one of the plants that can choose anticancer therapy because, based on reports, it has anticancer activity through DNA damage in cancer cells. This study focused on the search for the potential phytochemical activity of Plantago major L. as an anti-androgen, non-cytotoxic, and had significant AR inhibitory activity. This study uses Lipinski prediction (RO5), ADMET prediction, and a structure-based approach with molecular docking techniques using the PDB ID 2AM9 receptor structure and 13 compounds from Plantago major L. as test ligands compared to known AR antagonists. From the research results, Hispidulin has the highest potential as an anti-androgen with binding energy (-9.43 kcal/mol) that is closest to natural ligands and is smaller than Flutamide as a comparison drug. This anti-androgen activity was hypothesized from the similarity of hydrogen bonds with amino acid residues 705-Asn and 711-Gln as key AR residues present in Hispidulin.Keywords: Prostate cancer, Androgen Receptor, Plantago major L., ADMET, In Silico.
Identifikasi Keanekaragaman Tumbuhan Poaceae di Kampus II UIN Sumatra Utara Hartono, Adi; Tanjung, Indayana Febriani; S., Irwan
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 9, No 1 (2024): February 2024
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v9i1.4811

Abstract

Poaceae atau rumput-rumputan merupakan famili dari ordo Poales yang memiliki banyak manfaat dan pola penyebaran yang cukup luas di negara tropis, termasuk Indonesia. Hal ini dapat diamati melalui banyaknya tumbuhan dari famili Poaceae yang terdapat di lingkungan kampus II UIN Sumatra Utara. Namun, keberadaan tumbuhan tersebut belum diidentifikasi sehingga belum diketahui potensinya. Oleh sebab itu, penelitian ini bertujuan untuk mengidentifikasi keanekaragaman tumbuhan Poaceae yang ditemukan di kampus II UIN Sumatra Utara sekaligus menelaah potensi yang dimiliki oleh masing-masing ragam spesies tumbuhan tersebut. Metode penelitian yang digunakan dalam penelitian ini adalah survei eksploratif dan deskriptif, yaitu dengan melakukan pendataan tumbuhan serta mengamati morfologi dan deskripsi tumbuhan tersebut. Sampel tumbuhan dikoleksi dalam bentuk segar dan diidentifikasi di laboratorium Tadris Biologi FITK UINSU. Identifikasi tumbuhan menggunakan prosedur pendataan ciri morfologi tumbuhan dan kunci identifikasi yang bersumber dari buku karangan Gembong Tjitrosoepomo (2011). Hasil penelitian menunjukkan bahwa terdapat 11 genus dengan 12 spesies yang ditemukan di kampus II UIN Sumatra Utara.
Analisis Kemampuan Belajar Siswa dengan Penerapan Inkuiri pada Materi Sistem Ekskresi Halimatussa'diyah, enni; Hartono, Adi; Wahyu , Eka; Yanti , Depi; Marshelli, Melvi
Comit: Communication, Information and Technology Journal Vol. 2 No. 1 (2024): Comit: Communication and Information Journal
Publisher : IAI Nasional Laa Roiba Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47467/comit.v2i1.122

Abstract

Education plays an important role in improving the quality of human resources to create general welfare and educate the nation by forming a superior, quality, and competitive generation. This study aims to describe student learning outcomes in the biology learning process by using an inquiry learning model on the material of the human excretory system. This study uses the method of library research (library research), where the study is based on expert opinions about business ethics and its role in the company. In addition, this journal also uses the comparative study research method which aims to compare two or more variables to get answers or facts whether the comparison or not of the object under study. Based on the results of the discussion, it can be concluded that the inquiry learning model can improve students' critical thinking skills in biology subjects on excretion material. The use of inquiry learning models makes students able to understand the material well, plays an active role during the learning process, and improves students' critical thinking skills. Keywords: Inquiry, Excretion, Students
Students' Pedagogic Literacy Skills Based on Textbook Development Teaching Strategies in Biology Hasruddin, Hasruddin; Aryeni, Aryeni; Rezeqi, Salwa; Hartono, Adi
Jurnal Penelitian Pendidikan IPA Vol 10 No 3 (2024): March
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i3.7168

Abstract

The purpose of this study was to evaluate the pedagogical literacy skills of biology education students after studying lecture material from textbooks on biology teaching and learning strategies that have been developed based on the ADDIE model. This development research used 92 students of the Biology Education Study Program, FMIPA, State University of Medan as subjects, who were determined by random sampling technique. Pedagogic literacy is measured using an essay test to determine the ability of prospective teacher students according to developments in technology and communication. The data were analyzed by percentage technique. The results of the study found that students' pedagogic literacy abilities in preparing themselves for e-learning were included in the good category (82.45%), the use of digital learning in the very good category (91.84%), the learning components involved in online learning is included in the very good category (92.67%), and the use of authentic assessment is included in the good category (84.78%).
Science Learning Media for Elementary School Students Anas, Nirwana; Hartono, Adi
Jurnal Penelitian Pendidikan IPA Vol 10 No 11 (2024): November
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i11.9227

Abstract

The use of media in learning will provide a learning experience for students because it can involve more senses and give them the freedom to interpret. This study aims to: develop android-based science learning media for elementary school students, obtain android-based science learning media suitable for elementary school students, and determine the response of elementary school students to android-based science learning media. This research is a Research and Development (R&D) study. The development procedure consists of six steps, namely: analysis of potential problems, data collection, product design, design validation, design revision, and product testing. The assessment instrument used is a questionnaire sheet to test the quality of Android-based science learning media products. The assessment of the quality of Android-based science learning media products is conducted by reviewers, peer reviewers, elementary school (SD/MI) teachers, and the response of sixth-grade students. The results of this development research are as follows: 1) Android-based science learning media products on the topic of living organism reproduction for sixth-grade students of SD/MI have been developed, 2) the Android-based science learning media for sixth-grade students of SD/MI on the topic of living organism reproduction has been assessed by reviewers, peer reviewers, and SD/MI teachers with a rating of "Very Good" (SB) with a score of 631 and a percentage rating of 86.85%, and 3) the response of sixth grade students of SD/MI to the Android-based science learning media falls within the "Agree and Strongly Agree" interval, resulting in a score of 635 with a rating percentage of 88.23%.
Analysis of Student Learning Problems in Entomology Lectures Hartono, Adi
Bioeducation Journal Vol 9 No 1 (2025): Bioeducation Journal
Publisher : Universitas Negeri Padang Address: Biology Education Study Program Faculty Mathematics and Natural Science (FMIPA) Jl. Prof. Dr. Hamka Air Tawar Barat, Padang-West Sumatera-Indonesia Telp. +62751-7057420 - Fax.+62751-7058772 - Ph. +6281363229286

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/bioedu.v9i1.489

Abstract

This research aims to analyze various problems and difficulties of students in studying Entomology. The research was conducted using a survey method. The data collection technique uses a questionnaire containing 20 validated questions regarding aspects of students' learning difficulties in studying Entomology. The research data were analyzed descriptively using the Miles and Huberman approach which consists of three steps, namely: data reduction, data display, and data conclusion. The results of the research show that the dominant factor that causes problems for students in studying Entomology is material that they feel is confusing due to the many terms that must be mastered, the learning mechanism is not interactive, and the minimal use of media and reference sources that are interesting and relevant to the topic of the material being studied. Thus, it can be concluded that students' problems in taking Entomology courses lie in three main aspects, namely material, learning mechanisms, and references that are relevant to the topic being studied.
Sosialisasi Penerapan Video Interaktif pada Materi Proses Transpor dan Pertukaran Zat pada Manusia untuk Meningkatkan Kemampuan Kognitif Siswa Kelas XI di SMA Negeri 3 Langsa Hartono, Adi; Abdi, Egy
LOSARI: Jurnal Pengabdian Kepada Masyarakat Vol. 7 No. 2 (2025): Desember 2025
Publisher : LOSARI DIGITAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53860/losari.v7i2.512

Abstract

The community service activity is motivated by the low utilization of interactive technology in Biology education in schools, particularly in the topic of the processes of transport and exchange of substances in humans. The main focus of this activity is to enhance students' cognitive abilities through the implementation of interactive videos in Biology instruction. The aim of this service is to promote the use of interactive video media to teachers and 11th grade students at State High School 3 Langsa as an effort to transform learning in the digital era. The activity is carried out with a participatory approach through stages of socialization, demonstration of media usage, and evaluation of student understanding. The results of the activity demonstrate an increase in students' enthusiasm for learning, as well as an improvement in the average cognitive test scores following the use of interactive videos. This activity demonstrates that the integration of educational technology in Biology instruction can enhance the effectiveness of learning and reinforce students' understanding of concepts.
The implementation of quantum learning strategies in ecology materials to enhance students' creative thinking skills Hartono, Adi; Sarjani, Tri Mustika; Fitria, Dini; Sulaiman, Nanda Fahira
JPBIO (Jurnal Pendidikan Biologi) Vol 10, No 2 (2025): November 2025
Publisher : STKIP Persada Khatulistiwa Sintang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31932/jpbio.v10i2.5254

Abstract

Creative thinking is a key 21st-century skill that must be fostered in science education, particularly in ecology, which demands conceptual understanding and contextual problem solving. However, classroom learning often relies on conventional methods that limit student engagement and creativity. This study examines the effect of quantum learning strategies on improving students’ creative thinking skills in ecology. Quantum learning was selected for its holistic approach that integrates emotional, intellectual, and social dimensions, potentially optimizing creative stimulation. The research employed a quasi-experimental design with a pretest–posttest control group. Participants were 10th-grade students at SMA Negeri 11 Medan, divided into experimental and control groups. Data were collected using ecology-based creative thinking tests. The findings revealed a significant improvement in the creative thinking abilities of students in the experimental group compared to those in the control group. These results demonstrate that quantum learning effectively enhances students’ creativity in ecological learning contexts. The study suggests that adopting quantum learning strategies can help educators design more engaging and innovative learning environments aligned with 21st-century educational demands.
Keanekaragaman Tumbuhan Pewarna Alami dan Pola Pemanfaatannya oleh Masyarakat Suku Aceh Hartono, Adi; Sulaiman, Nanda Fahira; Arifah, Annisyah; Fauziani, Fauziani
Spizaetus: Jurnal Biologi dan Pendidikan Biologi Vol 7 No 1 (2026): Spizaetus: Jurnal Biologi dan Pendidikan Biologi
Publisher : Program Studi Pendidikan Biologi, FKIP, Universitas Nusa Nipa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55241/spibio.v7i1.703

Abstract

The use of plants as natural dyes represents important traditional knowledge of the Acehnese people, closely linked to cultural practices, crafts, and the use of local natural resources. However, modernization and synthetic dyes threaten the continuity of these traditions. This study aimed to examine the diversity of natural dye plants and their utilization patterns within Acehnese communities. A qualitative ethnobotanical approach was applied through field observations, semi-structured interviews with key informants, and documentation of dye-producing plant species. Data were analyzed descriptively by grouping plants based on parts used, colors produced, and forms of utilization. The findings show that various local plant species are used as natural dye sources, with leaves, bark, and fruits being the most commonly utilized parts. Utilization patterns are strongly connected to cultural needs and local wisdom in maintaining environmental balance. The study concludes that ethnobotanical knowledge of natural dyes persists despite modernization, highlighting its importance for preserving local knowledge and promoting environmentally friendly dye alternatives in cultural and applied science contexts.
Co-Authors Abdi, Egy Adisti, Yuda Adisti,  Yuda Agustina, Rezeki Sri Anas, Nirwana Anggara, Rizki Bob Arifah, Annisyah Armiati , Rika Armiati, Rika Artika, Dewi Nurul Aryeni Aryeni, Aryeni Ashar Hasairin Ayundari, Sella Baihaqi, Achmad Al Camara, Jun S. Dalimunthe, Rizka Ramadani Dalimunthe, Rizka Ramadhani Efrillia, Celline Fahira, Nanda Fauziani, Fauziani Fauziyyah, Ganis Fitria Febriyani, Emiliya Fitria, Dini Ginting, Fitri Febrianti Gunawan, Resta Halimatussa'diyah, enni Halimatussa’diyah, Enni Harahap, Mahfuza Delila Hariyadi, Itra Hasim, Hasrina Hasruddin HELMIWATI, HELMIWATI Hutabarat, Rismauli Ruth Natasari Indayana Febriani Tanjung, Indayana Febriani Isman, Hasna Siti Munifah KHAIRANI, MIFTAHUL Khairuna Khairuna Leo Pardon Sipayung, Leo Pardon Marshelli, Melvi MEGANTARA, SANDRA Milala, Rega Armanda Rastanutra Sembiring Miza Nina Adlini Munthe, Dea Wahdania Nirwana Anas Nurand, Amelia Putri Nurandi, Amelia Putri Pakpahan, Enni Halimatussa’diyah Pakpahan, Enny Halimatussa’diyah Purba, Rismaidah PUSPA SARI, TENGKU LUSI Putri, Amelisa Putri, Delia Putri, Eka Wahyu Rahma, Nur Izzaty Rezeqi, Salwa Ritonga, Eka Wahyu Putri M S., Irwan Saputri, Soraya Sarjani, Tri Mustika Shinta, Dewi Yudiana Silviani, Ninne Zahara Sonata MS3, Herix SOPIANA, ANA Sulaiman, Nanda Fahira Tampubolon, Sarah Witri Wahyu , Eka Yanti , Depi Yudiana, Dewi