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All Journal Farmaka Jurnal Kreativitas PKM Jurnal Farmamedika (Pharmamedica Journal) Abdi Laksana : Jurnal Pengabdian Kepada Masyarakat Edu Masda Journal Edu Dharma Journal: Jurnal penelitian dan pengabdian masyarakat Jurnal Farmasi dan Sains Indonesia (JFSI) Indonesian Journal of Health Science JURNAL PENDIDIKAN INDONESIA: Teori, Penelitian, dan Inovasi Jurnal Pengabdian Kolaborasi dan Inovasi IPTEKS Pharmaceutical Science Journal Jurnal Kefarmasian Indonesia JOURNAL OF Pharmacy and Tropical Issues
Aulia, Gina
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Formulation and Evaluation of Gummy Candy from the Extract of Jathropa Leaf (Jatropha curcas L.) Aulia, Gina; Sayyidah, Sayyidah; Fadhilah, Humaira; Ismaya, Nurwulan Adi; Indah, Fenita Purnama Sari
Jurnal Kefarmasian Indonesia VOLUME 13, NUMBER 2, AUGUST 2023
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v13i2.6429

Abstract

People are becoming more interested in nutraceutical preparations to maintain health as the world's health problems worsen. Jatropha curcas leaves (Jatropha curcas L.) have anthelmintic properties due to tannin compounds that act as anti-worms. This study aims to produce jelly candy preparations from Jatropha curcas leaves and evaluate these preparations. There are two stages of research: raw material preparation and verification, and jelly candy formulation. This study showed that the best concentration of Jatropha leaf extract was Formula 2. Based on the phytochemical test, there were alkaloids in the Jatropha leaf extract.  The pH value of gummy candies preparations of castor leaf extract, weight uniformity test, passed the moisture content test because they met the requirements for a wide range of dosage values. Meanwhile, the Hedonic Test results show that Formula 2 is the most preferred by children. So, based on the evaluation and hedonic test results, Formula 2 is the best preparation for jelly candy from jatropha leaves.
STROKE EMERGENCY HEALTH EDUCATION IN THE COMMUNITY OF PULO NYAMUK VILLAGE Sasmito, Priyo; Royani, Royani; Rustini, Ira; Aulia, Gina; Novena Simanjutak, Shania; Shinta Dewi, Yasmin; Robertus, Sumardi; Mutohharoh, Hopipah
Jurnal Pengabdian Kolaborasi dan Inovasi IPTEKS Vol. 1 No. 6 (2023): Desember
Publisher : CV. Alina

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59407/jpki2.v1i6.195

Abstract

The prevalence of stroke every year has increased significantly, and has become the third leading cause of disability and also the third cause of death in the world. In 2015, the World Health Organization (WHO) stated that every year there are 15 million people affected by stroke and become the leading cause of death after ischemic heart Stroke is a functional brain disorder disease in the form of paralysis of the nerves (neurological deficit) Stroke is the third cause of disability in the world due to impaired nerve function that occurs such as visual impairment, pelo speech, impaired mobility, as well as paralysis of the face and extremities. Conditions like this that cause stroke sufferers to have a high dependence on carrying out daily activities on others. (Oktarina &; Mulyani, 2020)Service activities will be carried out on October 22, 2023 in Pulo Mosquito Village Stroke health education activities are carried out at the homes of residents of Pulo Mosquito Village. The number of participants who attended was 22 people, this form of activity was carried out by the lecture method. Before starting health education activities, the community is given pre-test questions to find out the knowledge of the community about stroke. The material is delivered by lecture method using Leaflet media. Stroke health education activities are carried out at the homes of residents of Pulo Mosquito Village. The results of the post test given regarding knowledge about stroke found that the knowledge of the people of Kampung Pulo Nyamuk increased after being given counseling materials with the results of the post test value greater than the pre-test value. But it does not rule out the possibility that there are some people who have post-test values
Pengenalan Tanaman Obat yang Ada di Desa Gunungsari Kecamatan Cikatomas Kabupaten Tasikmalaya sebagai Solusi Pengobatan Alternatif Rahmawati, Rahmawati; Safitri, Putri Purnama; Zihan, Nindya Rahmi; Aafanisa, Farena; Pamungkas, Abi Rafdi Putra; Aulia, Gina
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 8, No 1 (2025): Volume 8 No 1 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v8i1.16557

Abstract

ABSTRAK Tanaman obat merupakan tanaman yang berguna sebagai obat dan digunakan untuk mencegah dan menyembuhkan. Berkhasiat obat sendiri berarti mengandung zat aktif yang dapat mengobati penyakit tertentu atau jika tidak memiliki zat aktif tertentu, tetapi memiliki efek resultan atau sinergi dari berbagai zat yang dapat mengobati penyakit. Untuk meningkatkan pemahaman masyarakat tentang manfaat dan cara pemanfaatan Tanaman Obat serta untuk membudidaya dan pengolahan tanaman obat, penyuluhan, dan dapat memanfaatkan kekayaan alam sekitar mereka untuk menyediakan pengobatan alternatif yang aman, efisien, dan murah. Observasi, wawancara, dokumentasi, serta sosialisasi penyuluhan. Menggunakan uji statistik T yang menunjukkan signifikan diperoleh nilai p-value sebesar (0.000) yang memperlihatkan bahwa terdapat perbedaan nilai rata-rata yang signifikan sebelum dan sesudah penyuluhan. Hal ini membuktikan bahwa kegiatan sosialisasi pengenalan tanaman obat yang ada di Desa Gunungsari dapat meningkatkan pengetahuan dan manfaat dari tanaman obat sebagai pengobatan alternatif. Kata Kunci: Sosialisai, Manfaat, Tanaman Obat, Obat Tradisional ABSTRACT Medicinal plants are plants that are useful as medicine and are used to prevent and cure. Medicinal efficacy itself means that it contains active substances that can treat certain diseases or if it does not have certain active substances, but has a resultant or synergistic effect from various substances that can treat diseases. To increase people's understanding of the benefits and ways of using medicinal plants as well as to cultivate and process medicinal plants, provide counseling, and be able to utilize the natural wealth around them to provide safe, efficient and cheap alternative medicine. Observation, interviews, documentation, and outreach. Using the T statistical test which shows significance, a p-value of (0.000) is obtained, which shows that there is a significant difference in average values before and after counseling. This proves that outreach activities regarding the introduction of medicinal plants in Gunungsari Village can increase knowledge and benefits of medicinal plants as alternative medicine. Keywords: Socialization, Stead, Medicinal Plants, Traditional Medicine
EFEKTIVITAS TERAPI INSULIN TERHADAP GLUKOSA DARAH DAN HbA1c PASIEN DIABETES MELITUS DI RUMAH SAKIT UMUM X JAKARTA SELATAN Aulia, Gina; Azzahra, Aristi; Purwaningsih, Neneng Sri; Ismaya, Nurwulan Adi; Hasanah, Nur; Putri, Annisa Septyana; Kurniawati, Dewi Indah; Werawati, Ayu; Sayyidah, Sayyidah
Jurnal Farmasi & Sains Indonesia Vol 7 No 2 (2024)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol7no2p167-172

Abstract

Diabetes mellitus is a serious and chronic condition. Diabetes mellitus patients often experience serious acute and chronic complications, even causing death. South Jakarta has the 4th highest prevalence of diabetes mellitus, namely 2.83%. The aim of this study was to analyze the effectiveness of insulin therapy by examining differences in blood glucose and HbA1c after 4 months and 8 months of therapy in diabetes mellitus patients. The research method in this research is quantitative descriptive analysis with a cohort retrospective approach. The sample in this study was 92 diabetes mellitus patients on insulin therapy who had their HbA1c checked with blood glucose routinely in 2023 taken using the purposive sampling method. The results showed that most patients were in the 56-65 years age group (45.7%), the most common gender was female (57.6%), and 76.1% of patients had comorbidities. The most widely used insulin therapy is a combination of Rapid acting and Long acting insulin (63%). The conclusion in this study was that there was no significant difference in either blood glucose levels after 4 months of therapy (P=0.442) or blood glucose levels after 8 months of therapy (P=0.148), compared with 1st month blood glucose, and there was a difference significant both HbA1c levels after 4 months of therapy (P=0.000) and HbA1c levels after 8 months of therapy (P=0.000), compared with HbA1c in the 1 month
PENGARUH SENYAWA FITOKIMIA DALAM REBUSAN DAUN KELOR (MORINGA OLEIFRA) DAN SELEDRI (APIUM GRAVEOLENS) TERHADAP PENURUNAN TEKANAN DARAH Hasanah, Nur; Ismaya, Nurwulan Adi; Satria, Beny Maulana; Aulia, Gina; Sitorus, Ratna
Edu Masda Journal Vol 9, No 1 (2025): EDU MASDA JOURNAL
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v9i1.264

Abstract

                                                        ABSTRACTBackground: Hypertension is a condition characterized by elevated blood pressure, which can lead to persistent damage in target organs, such as stroke and cardiovascular disease. Purpose: This study aimed to evaluate the effect of moringa and celery leaf decoction on reducing blood pressure in individuals with hypertension. Methods: A pre-experimental one-group pretest-posttest design was employed, involving 40 respondents diagnosed with hypertension. The independent variable was the administration of moringa and celery leaf decoction, while the dependent variable was blood pressure levels. Data were analyzed using the Wilcoxon signed-rank test. Results: The results demonstrated that consuming moringa and celery leaf decoction effectively reduced blood pressure. The Wilcoxon test showed a significant reduction in blood pressure, with a p-value of 0.05. Conclusion: The study concluded that moringa and celery leaf decoction have a significant effect in lowering blood pressure among hypertensive patients in Buaran, Serpong sub-district, South Tangerang City. This finding highlights the potential of herbal medicine as an alternative non-pharmacological treatment for hypertension.                                                                   ABSTRAKLatar Belakang: Hipertensi adalah masalah kesehatan global yang berkontribusi besar terhadap morbiditas dan mortalitas, menyebabkan penyakit jantung, stroke, dan gagal ginjal. Meskipun sering tanpa gejala, hipertensi dapat merusak organ secara bertahap, menjadikannya salah satu penyebab utama kematian. Oleh karena itu, penelitian hipertensi sangat penting untuk menemukan solusi pengobatan yang efektif. Salah satu alternatif yang menjanjikan adalah daun kelor (Moringa oleifera), yang terbukti memiliki sifat antihipertensi dan dapat menjadi pilihan pengobatan alami untuk membantu mengelola kondisi ini.. Tujuan: Penelitian ini bertujuan untuk mengevaluasi efek air rebusan daun kelor dan seledri dalam menurunkan tekanan darah pada penderita hipertensi. Metode: Penelitian ini menggunakan desain pra-eksperimen dengan pendekatan pretest-posttest satu kelompok, melibatkan 40 responden yang didiagnosis hipertensi. Variabel independen adalah pemberian rebusan daun kelor dan seledri, sedangkan variabel dependen adalah tingkat tekanan darah. Data dianalisis menggunakan uji Wilcoxon. Hasil: Hasil penelitian menunjukkan bahwa konsumsi rebusan daun kelor dan seledri efektif menurunkan tekanan darah. Uji Wilcoxon menunjukkan penurunan tekanan darah yang signifikan dengan nilai p = 0,05. Kesimpulan: Rebusan daun kelor dan seledri memiliki efek signifikan dalam menurunkan tekanan darah pada penderita hipertensi di Kelurahan Buaran, Kecamatan Serpong, Kota Tangerang Selatan, sehingga rebusan daun kelor dan seledri berpotensi sebagai minuma herbal sebagai alternatif non-farmakologis untuk hipertensi. 
Pola peresepan obat pada pasien gagal ginjal kronis rawat inap rumah sakit x Tangerang Selatan Aulia, Gina; Holidah, Holidah; Pratiwi, Rita Dwi; Rini, Wahyu Sulistyo
JOURNAL OF Pharmacy and Tropical Issues Vol. 4 No. 2 (2024): December Edition 2024
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR) Kerjasama dengan Ikatan Sarjana Farmasi Indonesia (ISFI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/pti.v4i2.533

Abstract

Background: Kidney failure is a condition in which kidney function decreases or even disappears in several stages. Chronic renal failure was defined as kidney damage and/or decreased Glomerular Filtration Rate of less than 60ml/min/1.73 m2 for at least three months. Prescribing the right disease treatment is an important factor in the healing process, especially chronic kidney failure. Purpose: To determine the pattern of prescribing chronic kidney drugs inpatients at RS X Tangerang Selatan in 2019. Methods: Descriptive with secondary data random sampling technique, from medical records and doctor's prescriptions. Patient characteristics include age and gender, indicators of prescription patterns including drug class, drug form, amount and dose. The population obtained was 264 patients with 159 patients used as samples. Results: Patients aged over 65 years (41.51%), male (57.23%), antacid drug group (31.63%), tablet form (65.06%), the most widely used was Bicnatric (16.87) dose of 500 mg (22.40%). ). Conclusion: Patients diagnosed with chronic kidney failure who were hospitalized at RS X Tangerang Selatan in 2019 were mostly men aged over 65 years and the most widely used drug was Bicnatric tablet 500 mg (Antasida). Keywords: Recipe Pattern; Patient; Kidney Failure; Chronic; Inpatient Pendahuluan: Gagal ginjal merupakan suatu kondisi dimana fungsi ginjal telah menurun atau bahkan menghilang dalam beberapa tahap. Gagal ginjal kronis didefinisikan sebagai kerusakan ginjal dan atau penurunan Laju Filtrasi Glomerulus kurang dari 60ml / menit / 1,73 m2 selama setidaknya tiga bulan. Peresepan pengobatan penyakit yang tepat merupakan faktor penting dalam proses penyembuhan, terutama gagal ginjal kronis. Tujuan: Untuk mengetahui pola peresepan obat rawat inap ginjal kronik di Rumah Sakit X Tangerang Selatan pada tahun 2019. Metode: Deskriptif dengan teknik sekunder data random sampling, dari rekam medis dan resep dokter. Bentuk karakteristik pasien termasuk usia dan jenis kelamin, indikator pola resep termasuk golongan obat, bentuk obat, jumlah dan dosis. Populasi yang diperoleh adalah 264 pasien dengan 159 pasien telah digunakan sebagai sampel. Hasil: Usia pasien di atas 65 tahun (41,51%), laki-laki (57,23%), kelas obat antasid (31,63%), bentuk tablet (65,06%), yang paling banyak digunakan adalah Bicnatric ( 16,87) dosis 500 mg (22,40%). Simpulan: Pasien yang didiagnosis dengan gagal ginjal kronis rawat inap di rumah sakit X Tangerang Selatan pada tahun 2019 sebagian besar terjadi pada pria berusia di atas 65 tahun dan obat yang paling banyak digunakan adalah tablet Bicnatric 500 mg (Antasida). Kata Kunci: Pola Resep; Pasien; Gagal Ginjal Kronis; Rawat Inap
Rational use of NSAIDs and the incidence of potential drug interactions in inpatients with osteoarthritis at the Tangerang City General Hospital Fauziah, Siva; Aulia, Gina; Nasar, Nur Afni Syariah; Putri, Annisa Septyana; Komarudin, Dede
Indonesian Journal of Health Science Vol 5 No 4 (2025)
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/ijhs.v5i4.1621

Abstract

Background: Osteoarthritis (OA) is a disease that affects articular cartilage, subchondral bone, synovium, capsule, and ligaments. This disease is an overlapping disorder with different etiologies but similar biological, morphological, and clinical outcomes. The rationality of drug use in osteoarthritis must be optimized to achieve optimal therapeutic outcomes. The potential for drug interactions must also be understood to prevent unwanted effects from therapy. Objective: To determine the rationality of drug use and the potential for drug interactions in osteoarthritis patients at Tangerang City General Hospital, focusing on the four principles of appropriate drug use: appropriate patient, appropriate drug, appropriate indication, and appropriate dose. This study is a descriptive observational study with a cross-sectional design and uses retrospective data. Method: The study sample was selected using purposive sampling, considering inclusion and exclusion criteria. The study sample meeting the inclusion criteria consisted of 31 medical records (patients). The data obtained were then compared with the reference standards of the Indonesian Rheumatology Association (IRA). Results: Patient characteristics based on age showed the highest proportion in early elderly (46–55 years) at 41.9%, female gender at 71%, with joint pain location in the feet at 65%, other joints at 23%, and hands at 12.9%. The profile of prescribed osteoarthritis medications was as follows: sodium diclofenac 41.9%, meloxicam 38.7%, ketorolac 12.9%, and mefenamic acid 6.5%. The rationality of patient accuracy, medication, indications, and dosage yielded 100% data related to NSAID use in osteoarthritis patients, with the highest potential for drug interactions occurring in the combination of sodium diclofenac and bisoprolol at 18.2% at a moderate severity level. The mechanism of interaction involves NSAIDs potentially weakening the antihypertensive effects of beta-blockers. The mechanism of NSAID-induced inhibition of renal prostaglandin synthesis results in uninhibited pressor activity, leading to hypertension. Additionally, NSAIDs can cause fluid retention, which also affects blood pressure. Conclusion: The rational use of NSAIDs in terms of the right patient, right drug, right indication, and right dose was 100%, and the total number of PIAO cases found was 11 (28.2%). Of all the cases identified, 8 cases were moderate in severity and 3 cases were minor. The most common drug interactions were between Sodium Diclofenac and Bisoprolol, accounting for 18.2%. Keywords: Drug rationality NSAIDs, Osteoarthritis, Potential drug interactions.
Efektivitas ekstrak Etanol Rosemary (Rosemarinus officinalis L.) pada tikus jantan putih (Rattus Norvegicus L.) sebagai agen Hepatoprotektor Komarudin, Dede; Adriana, Yulis; Ruslihagi, Farid; Fauziah, Siva; Putri, Annisa Septyana; Aulia, Gina; Nasar, Nur Afni Syariah
Indonesian Journal of Health Science Vol 5 No 4 (2025)
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/ijhs.v5i4.1622

Abstract

Latar Belakang: Hati adalah organ penting dalam tubuh manusia.kerusakan pada hati disebabkan oleh banyak faktor termasuk obat-obatan tertentu, paparan polutan, dan bahan kimia lingkungan seperti parasetamol, karbon tetraklorida, dan lain-lain. triklorometil membentuk radikal triklorometilperoksi Peroksidasi lipid, gangguan homeostasis Ca2, dan N-acetylcysteine Tanaman Rosmarinus officinalis L. kadang-kadang dikenal sebagai rosemary atau rosmarin, merupakan anggota famili Lamiaceae dan rosemary memiliki efek antioksidan serta hepatoprotektif. Tujuan: Studi ini untuk menguji efektivitas antioxidant ekstrak Rosemary dan sebagai agen hepatoprotektor pada tikus jantan putih. Metode: Penelitian ini dilakukakan secara eksperimental dengan melakukan  ekstraksi etanol 80% Rosemary untuk menguji efektivitas antioksidan yang diujikan kepada hewan tikus 30 ekor terbagi menjadi 6 kelompok dan terdiri dari 5 ekor tikus yang masing-masing hanya di induksi karbon tertaklorida (CCL4): induksi CCL4 & obat pembanding; induksi CCL4  dan ekstrak rosemary dosis 80%, 100% dan 120% serta tikus yang hanya di beri makan dan minum kemudian untuk mengetahui penurunan dan dosis optimalnya berdasarkan kadar AST (Aspartate Aminotransferase) dan ALT (Alanine Aminotransferase). Hasil : Pengukuran setelah diinduksi CCL4 didapatkan kadar rata-rata AST & ALT masing-masing kelompok 1-6 yaitu 60 & 25,6; 155,8 & 154,6; 165 & 153,2; 149,8 & 139,4; 150,6  &147,2; 168,8 & 151 U/L. Pengukuran kadar AST dan ALT setelah dilakukan pemantauan dan perlakuan pada hari ke 1 berturut-turut yaitu 60 & 25,6; 155,8 & 154,6; 165 & 153,2; 149,8 & 139,4; 150,6 & 147,2; 168,8 & 151 U/L. Pada hari ke 7 yaitu 57,6 & 23; 113,4 & 92,4; 160,2 & 149; 114,4 & 102,8; 118.6 & 88,4; 96 & 84,6 U/L.  Pada hari ke 14 yaitu 57 & 22,4; 60 & 27; 128,2 & 123,4; 103,2 & 56,6; 70 & 38,8; 58,2 23,4 U/L. Kesimpulan: Ekstrak Rosemary berpotensi sebagai Hepatoprotektor karena dapat menurunkan aktivitas kadar ALT dan AST pada tikus putih jantan yang telah diinduksikan CCl4 dengan dosis optimum yang dapat digunakan sebagai hepatoprotektor pada dosis 100-120%.
TINGKAT KEPUASAN PASIEN TERHADAP PELAYANAN KEFARMASIAN OLEH APOTEKER DI PUSKESMAS X TANGERANG SELATAN Susanti, Debi; Mutiasih , Pipit; Aulia, Gina; Rahmah Fahriati, Andriyani
Jurnal Farmamedika (Pharmamedika Journal) Vol 10 No 2 (2025): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47219/ath.v10i2.498

Abstract

Pelayanan kefarmasian merupakan serangkaian kegiatan yang bertujuan untuk mengidentifikasi, mencegah, serta mengatasi masalah terkait obat dan kesehatan. Dalam upaya meningkatkan mutu pelayanan, pendekatan pelayanan kefarmasian perlu bergeser dari yang berfokus pada obat (drug oriented) menjadi berorientasi pada pasien (patient oriented). Oleh karena itu, apoteker dituntut untuk terus meningkatkan kompetensinya agar mampu memberikan pelayanan yang menyeluruh dan berkesinambungan. Kualitas layanan kesehatan, khususnya dalam bidang kefarmasian, sangat menentukan kepuasan pasien, yang didefinisikan sebagai tingkat kepuasan yang dirasakan setelah membandingkan harapan dengan kenyataan layanan yang diterima. Tujuan dari penelitian ini adalah untuk mengetahui tingkat kepuasan pasien terhadap pelayanan kefarmasian oleh apoteker di Puskesmas X Tangerang Selatan. Penelitian ini bersifat observasional analitik dengan desain potong lintang (cross-sectional), dilakukan pada tanggal 27 Mei hingga 29 Juni 2024, menggunakan kuesioner terhadap 334 responden yang dipilih melalui teknik accidental sampling. Tingkat kepuasan diukur berdasarkan lima dimensi, yaitu kehandalan, ketanggapan, jaminan, empati, dan bukti fisik. Data dianalisis menggunakan Microsoft Excel dan SPSS. Hasil menunjukkan tingkat kepuasan pada kehandalan sebesar 78,81%, ketanggapan 80,67%, jaminan 82,91%, empati 81,90%, dan bukti fisik 78,71%. Secara keseluruhan, tingkat kepuasan terhadap pelayanan kefarmasian oleh apoteker mencapai 80,35% dan termasuk dalam kategori sangat puas. Sementara itu, hasil uji hubungan antara karakteristik pasien dan tingkat kepuasan menunjukkan nilai P > 0,05, yang berarti tidak terdapat hubungan yang signifikan. Kesimpulannya, pasien merasa sangat puas dengan pelayanan kefarmasian yang diberikan oleh apoteker di Puskesmas X Tangerang Selatan
UJI AKTIVITAS ANTELMINTIK SIRUP EKSTRAK ETANOL UMBI BATANG ROTAN (CALAMUS ROTANG L.) TERHADAP CACING GELANG (ASCARIDIA GALLI) SECARA IN VITRO Herdaningsih, Sulastri; Inderiyani, Inderiyani; Fauzan, Suhaimi; Aulia, Gina
Edu Masda Journal Vol 9, No 1 (2025): EDU MASDA JOURNAL
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v9i1.278

Abstract

                                                   ABSTRACTAnthelmintics are drugs used to eradicate worms from the human or animal body. This study aims to determine whether ethanol extract of rattan stem tubers can be formulated as a syrup preparation and to determine how the physical evaluation of ethanol extract syrup preparation of rattan stem tubers. The research method used was laboratory experimental design. The test animals used were 75 heads, which were divided into 5 groups with 3 replications. The research was conducted with activity tests using Ascaridia galli worms soaked in rattan stem tuber extract syrup (Calamus rotang L.) with concentrations of 0.5%; 0.75%; and 1%. Piperazine citrate 0.9% was used as positive control and NaC1 0.9% physiological solution as negative control. Observations were made every 15 minutes by looking at whether lysis occurred in the worms. The results of testing the activity of rattan stem tuber extract showed that all concentrations of rattan stem tuber extract syrup (0.5%; 0.75%; and 1%) had a mortality percentage of 100%. Statistical results at concentrations of 0.75% and 1% are not significantly different from the positive control (> 0.05). This shows that rattan stem tuber extract syrup (Calamus rotang L.) has anthelmintic activity.                                       ABSTRAKABSTRAKAntelmintik merupakan obat yang digunakan untuk memberantas cacing dari dalam tubuh manusia atau hewan. Penelitian ini bertujuan untuk mengetahui apakah ekstrak etanol umbi batang rotan dapat diformulasikan sebagai sediaan sirup dan untuk mengetahui bagaimana evaluasi fisik sediaan sirup ekstrak etanol umbi batang rotan. Metode penelitian yang digunakan adalah desain eksperimental laboratorium. Hewan uji yang digunakan sebanyak 75 ekor, yang dibagi menjadi 5 kelompok dengan 3 replikasi. Penelitian dilakukan dengan uji aktivitas menggunakan cacing Ascaridia galli yang direndam dalam sirup ekstrak umbi batang rotan (Calamus rotang L.) dengan konsentrasi 0,5%; 0,75%; dan 1%. Pada kontrol positif digunakan Piperazine sitrat 0,9 % dan larutan fisiologis NaC1 0,9 % sebagai kontrol negatif. Pengamatan diakukan tiap 15 menit dengan cara melihat apakah terjadi lisis pada cacing. Hasil pengujian aktivitas ekstrak umbi batang rotan menunjukkan bahwa semua konsentrasi sirup ekstrak umbi batang rotan (0,5%; 0,75%; dan 1%) memiliki persentase mortalitas sebesar 100%. Hasil statistik pada kosentrasi 0,75% dan 1% tidak berbeda makna dengan kontrol positif (> 0,05). Hal ini menunjukan bahwa sirup ekstrak umbi batang rotan (Calamus rotang L.) memiliki aktivitas sebagai antelmintik.
Co-Authors Aafanisa, Farena Agung Dewantoro Al-Hafiz, Mohammad Alexandre, Nahla Dany Andriyani Rahmah Fahriati Arief, Ilham Asmara, Ratna Dewi Lintang Ayu Werawati Azzahra, Aristi Beny Maulana Satria Bheta Sari Dewi Dede Komarudin Desy Darmayanti Fauzan, Suhaimi Fenita Purnama Sari Indah Fitriani, Reka Gita Ayuningtyas Hairunnisa Hairunnisa Herdaningsih, Sulastri Herdaningsih, Sulatri Holidah Holidah, Holidah Humaira Fadhilah Inderiyani, Inderiyani Kristiyowati, Anis Dwi Kurniawati, Dewi Indah Luciana Luciana Mutiasih , Pipit Mutohharoh, Hopipah Nasar, Nur Afni Syariah Neneng Sri Purwaningsih Novena Simanjutak, Shania Nur Hasanah Nurhaetami, Cut Intan Nurihardiyanti Nurihardiyanti, Nurihardiyanti Nurwulan Adi Ismaya Pamungkas, Abi Rafdi Putra Puji Rahayu Putra, Rifqi Sonia Putrajaya, Fadly Putri, Annisa Septyana Rahmawati, Rahmawati Ratna Sitorus Rini, Wahyu Sulistyo RIRIS ANDRIATI Rita Dwi Pratiwi Robertus, Sumardi ROYANI ROYANI Ruslihagi, Farid Rustini, Ira Safitri, Putri Purnama Saputri, Laras Tri Sasmito, Priyo Sayyidah, Sayyidah Setiawan, Usep Shinta Dewi, Yasmin Siti Novy Romlah Siva Fauziah, Siva SORAYA RATNAWULAN MITA, SORAYA RATNAWULAN Sulistyo Rini, Wahyu Sumarwati Susanti, Debi Tania Rizki Amalia Taniawati Supali Uswatun Hasanah Yenny Djuardi Yulis Adriana Zahra, Annisa Fairuz Zihan, Nindya Rahmi