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All Journal JIMKesmas (Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) The Indonesian Biomedical Journal Syntax Literate: Jurnal Ilmiah Indonesia Poltekita : Jurnal Ilmu Kesehatan Jurnal Kesmas Prima Indonesia Jurnal Prima Medika Sains Science Midwifery Jurnal Promotif Preventif Jurnal Kesehatan Tambusai Jurnal Penelitian Inovatif Action Research Literate (ARL) Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Buletin Kedokteran dan Kesehatan Prima
Lina, Juliana
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Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Histopathological characteristics of soft tissue tumors at Madani General Hospital Nasution, Prenan Dito Perdana; Lina, Juliana; Wardhani, Fiska Maya; Loren, Jeff; Muchtar, Muhammad Arafat; Iskandar, Ari Rahman
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 2 (2024): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i2.5677

Abstract

Benign tumors were more common than malignant tumors, with a ratio of 1:100. However, in 2019, approximately 13,000 cases of malignant tumors were reported in the United States. Based on data from Cancer Referral Hospitals in Indonesia, soft tissue sarcomas were among the ten most common cancers in 2013, with approximately 75% of cases occurring in the extremity region. This study aimed to describe the histopathological examination results of patients with soft tissue tumors at the Madani General Hospital, Medan City. This study used a retrospective descriptive design by collecting data from the medical records of patients who underwent histopathological examination at the Anatomical Pathology Laboratory of Madani General Hospital (period 2018-2022). Data were analyzed based on the distribution of cases according to age, sex, and tumor type. The results showed that soft tissue tumors were most prevalent in the 41-50 age group with 30 patients (20.3%), the majority were female with 85 patients (57.4%), and based on histopathological diagnosis, lipoma was the most common type of tumor found in 70 patients (47.3%). All cases studied were benign tumors, with a total of 148 patients (100%).
Genetic factor, short-distance activity, and myopia among medical students Tiswan, Jiad Hanan; Pratama, Irza Haicha; Lina, Juliana; Ivonne, Ivonne; Purwoko, Heri; Yumardika, Deza
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 2 (2024): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i2.6160

Abstract

Myopia, a common refractive error, has seen a significant global increase, particularly among young adults. This study aims to investigate the association between genetic factors, short-distance activity, and the incidence of myopia among medical students. A cross-sectional survey design was employed to collect data from medical students in batches 2022 and 2023. Chi-square tests were used to analyze the relationship between the variables. Demographic data revealed a predominantly young female population, with a high proportion of students enrolled in the 2023 academic year. A significant number of students were diagnosed with myopia, ranging from low to high degrees. Risk factor analysis indicated a strong association between reduced short-distance activity and increased myopia risk. Additionally, a family history of myopia emerged as a significant genetic predisposition to the condition. These findings highlight the importance of addressing both environmental and genetic factors to prevent and manage myopia among medical students. Future longitudinal studies with larger sample sizes are needed to further explore the temporal relationship between risk factors and myopia progression.
Squamous cell carcinoma of the kidney: A case report Lina, Juliana; Karo, Reh Malem br; Theresia, Yohani; Fadillah, Qori
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6544

Abstract

Primary renal squamous cell carcinoma (SCC) is a rare neoplasm strongly associated with a history of nephrolithiasis. Renal SCC is reported to have high morbidity and mortality rates, especially in the elderly population. Clinical manifestations of renal SCC are generally characterized by hematuria, flank pain, and a palpable mass in the retroperitoneal area. Histopathological examination reveals the infiltration of squamous cell nests that destroy the stroma. These cells show nuclear pleomorphism, an increased nuclear/cytoplasmic ratio, irregular nuclear membranes, coarse chromatin, prominent and dense basophilic nucleoli, and eosinophilic cytoplasm. These histopathological findings confirm the diagnosis of squamous cell carcinoma. The uniqueness of this case lies in the diagnosis of renal SCC in a relatively young age group, making it a distinct clinical concern. Further immunohistochemical examination, including CK5/6, p63, p40, and CK14 panels, is needed to determine the prognosis and appropriate treatment strategy. This case report emphasizes the importance of understanding kidney stone disease as a preventive measure against the development of renal SCC.
Karakteristik Penderita Kanker Sistem Reproduksi Dan Payudara Di Laboratorium Rumah Sakit Umum Madani Periode 2019-2024 Sintya, Inda Dhea; Lina, Juliana; Lister , Clarissa
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i10.62380

Abstract

Objective: To determine the general characteristics of reproductive and breast cancer patients at the Madani General Hospital Laboratory from 2019 to 2024. Method: This study used a descriptive correlational approach. The research began in December 2024 with proposal writing, followed by research in February 2025 until data collection, which was then followed by a results seminar. The accessible population consisted of all medical records of reproductive and breast cancer patients at the Madani General Hospital Laboratory, a sample size of 32, using a purposive sampling technique. Univariate data analysis was presented in the form of frequency distributions, while bivariate analysis used the chi-square test. Data processing was performed using the computerized IBM SPSS version 25.0. Results: The highest number was in the age group of 52-56 years, totaling 8 people (25%), almost half of the respondents had an origin organ of endometrium and breast, totaling 12 people (41.4%), and almost half of the respondents had of the respodents had a diagnosis of endometrial adenocarcinoma. There was a correlation between organ origin and diagnosis in patients with reproductive system and breast cancer at the Madani General Hospital Laboratory during the 2019-2024 period (p=0.000). There was no correlation between age and diagnosis in patients with reproductive system and breast cancer at the Madani General Hospital Laboratory during the 2019-2024 period (p=0.097). Conclusion: There was a correlation between origin organ and diagnosis, but no correlation between age and diagnosis in patients with reproductive system and breast cancer at the Madani General Hospital Laboratory during the 2019-2024 period.
Examining the Impact of Candlenut Fruit Extract Cream on Hair Growth in Male Wistar Rats (Rattus norvegicus) Fitriani, Anche Pratiwi; Wijaya, Johana Fransiska; Lina, Juliana; Fibrini, Dewi
Poltekita : Jurnal Ilmu Kesehatan Vol. 17 No. 4 (2024): February
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v17i4.3613

Abstract

Hair loss can affect mental health. Natural compound-based hair treatments like candlenut fruit are becoming more popular due to their low side effects and growing scientific research on hair loss. This study aims to prove the effectiveness of candlenut fruit extract cream on the hair growth of male Wistar strain rats (Rattus norvegicus). Research method Laboratory experiment, Principle 3R (Replacement, Reduction, and Refinement): Reducing Rattus norvegicus Wistar male strain samples The 20 male rats in this study will be divided into four groups. Hair growth is examined with 5%, 10%, and 15% candlenut fruit extract cream. Research data was analyzed using SPSS. The results of testing hair growth in rats with 5%, 10%, and 15% doses of candlenut fruit extract cream were normally distributed. The control group had a significant value of 0.928 > 0.05, treatment group 1 had a value of 0.579 > 0.05, treatment group 2 of 0.829 > 0.05, and treatment group 3 of 0.451 > 0.05. Candlenut fruit extract cream is effective for increasing hair growth in Rattus norvegicus. This study concludes that candlenut fruit extract cream can accelerate the development of hair follicles in Wistar strain male white rats. Due to the heated manufacturing process, candlenut extract is safe to use.
Hypoglycemic Activity and Safety Assessment of Pediococcus acidilactici Strain DNH16 in Experimental Type 2 Diabetes Mellitus Rats Induced with Streptozotocin Fachrial, Edy; Lina, Juliana; Harmileni, Harmileni; Anggraini, Sari; Sihotang, Widya Yanti
The Indonesian Biomedical Journal Vol 16, No 1 (2024)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v16i1.2781

Abstract

BACKGROUND: Type 2 diabetes mellitus (T2DM) cases tend to rise throughout the year in all parts of the world. The α-glucosidase inhibitors are frequently used to both prevent and treat T2DM. This α-glucosidase inhibitor activity is seen in some probiotic species, and a certain strain of Pediococcus acidilactici exhibits promising characteristics as an α-glucosidase inhibitor. This study was conducted to assess the hypoglycemic activity and safety of P. acidilactici strain DNH16 (PADNH16) in experimental rats with T2DM induced by streptozotocin.METHODS: The experiment was conducted in vivo using Wistar rats. Acarbose was employed as a positive control, and Lactobacillus casei was used as a comparative. For 24 days, post-prandial blood glucose levels were assessed every 3 days, followed by serum biochemical levels measurement of liver, kidney, and lipid profiles. The pancreas was histopathologically examined utilizing the Hematoxyline-Eosin staining procedure.RESULTS: Administration of PADNH16 to T2DM rats lowered post-prandial blood glucose levels and gave hypoglycemic benefits comparable to acarbose and commercial probiotics. PADNH16 dosing did not affect serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT), urea, or creatinine levels, showing that PADNH16 was not hazardous to liver or kidney function. The lipid profile assessment revealed that the values, including high-density lipoprotein (HDL), low-density lipoprotein (LDL), and triglycerides, were comparable to the control group. The pancreatic histopathology revealed that injection of PADNH16 caused no alterations to pancreatic β cells.CONCLUSION: P. acidilactici isolate DNH16 has a hypoglycemic effect on T2DM rats, but does not affect liver function enzymes, kidneys, lipid profiles and does not provide significant changes in pancreatic β cells.KEYWORDS: diabetes mellitus, inhibitor α-glucosidase, Pediococcus acidilactici strain DNH16
KARAKTERISTIK PENDERITA TUMOR SISTEM REPRODUKSI WANITA DENGAN PEMERIKSAAN HISTOPATOLOGI DI RUMAH SAKIT UMUM MADANI MEDAN PERIODE TAHUN 2018 – 2022 Amanda, Carissa; Lina, Juliana; Wardhani, Fiska Maya
Jurnal Kesehatan Tambusai Vol. 5 No. 3 (2024): SEPTEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i3.32745

Abstract

Tumor sistem reproduksi wanita merupakan jenis sel tumor yang dapat tumbuh di berbagai organ sistem reproduksi wanita. Berdasarkan data Rikesdas, pravelensi tumor di Indonesia tahun 2018 terdapat 1.017.290 (1,79%) dari 278,8 juta penduduk. Tujuan penelitian untuk mengetahui karakteristik penderita tumor sistem reproduksi wanita dengan pemeriksaan histopatologi di Rumah Sakit Umum Madani Medan Periode Tahun 2018–2022. Jenis penelitian menggunakan pendekatan deskriptif retrospektif, sumber data yang diambil data sekunder yaitu rekam medik dengan metode total sampling sebanyak 234 orang. Analisis hasil penelitian dilakukan dengan analisis statistik frekuensi menggunakan SPSS. Berdasarkan kelompok usia terbanyak yang mengalami tumor sistem reproduksi wanita adalah usia 36-45 tahun sebanyak 103 orang (44,0%), berdasarkan diagnosa histopatologi terbanyak adalah Leiomyoma Uteri sebanyak 129 orang (55,1%), berdasarkan jenis tumor terbanyak adalah tumor jinak sebanyak 234 orang (100%), berdasarkan lokasi tumor terbanyak adalah tumor uterus sebanyak 131 orang (56,0%). Penderita Endometriosis mayoritas berada pada kelompok usia 26–35 tahun sebanyak 16 orang (14,6%), penderita Leiomyoma Uteri mayoritas berusia 36-45 tahun sebanyak 64 orang (62,1%), penderita Mucinous Cystadenoma Ovarii mayoritas berusia 36–45 tahun sebanyak 13 orang (12,6%), penderita Serous Cystadenoma Ovarii mayoritas berusia 36–45 tahun sebanyak 8 orang (7,8%), dan penderita Mature Teratoma mayoritas berusia 26–35 tahun sebanyak 9 orang (2,9%). Mayoritas penderita yang mengalami tumor jinak berada pada kelompok usia 36–45 tahun sebanyak 103 orang (100%). Mayoritas penderita yang mengalami tumor jinak adalah tumor Leiomyoma Uteri sebanyak 129 orang (100%).
PENGARUH CURCUMA ZEDOARIA TERHADAP GAMBARAN HISTOPATOLOGI HEPAR TIKUS WISTAR DIABETIK Putri, Nabila dwi; Lina, Juliana; Wardhani, Fiska Maya; Hyachinta, Izdihar Putri; Hasibuan, Selly Rahmadiah
Jurnal Kesehatan Tambusai Vol. 5 No. 3 (2024): SEPTEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i3.32848

Abstract

Diabetes melitus merupakan penyakit yang menyerang banyak orang di seluruh dunia dan memerlukan pengobatan jangka panjang, bahkan seumur hidup, sehingga menimbulkan biaya pengobatan yang tinggi dan efek samping jangka panjang dari obat antidiabetes. Banyak orang yang memanfaatkan kunyit putih sebagai obat alternatif yang dinilai memiliki efek antidiabetes dan efek samping yang minim. Tujuan penelitian ini adalah untuk mengetahui pengaruh ekstrak kunyit putih terhadap kadar gula darah dan gambaran histopatologi hati. Penelitian ini merupakan penelitian eksperimental dengan metode the post only group design yang melibatkan 30 ekor Rattus norvegicus jantan meliputi berat badan 180-220 gram dan berusia 6-8 minggu. Tikus putih dibagi menjadi kelompok normal, kelompok negatif, dan kelompok perlakuan dengan dosis 250 mg/KgBB, 500 mg/KgBB, 750 mg/KgBB. Hasil yang diperoleh menunjukkan bahwa ekstrak kunyit putih (Curcuma zedoaria) dengan dosis 250 mg/KgBB , 500 mg/KgBB dan 750 mg/KgBB dapat menurunkan kadar gula darah tetapi pada gambaran histopatologi hati dengan dosis 250 mg/KgBB menunjukkan adanya degenerasi, ini dikarenakan sampel sudah memiliki riwayat penyakit dan efek pemberian aloksan. Namun pada dosis 500 mg/KgBB dan 750 mg/KgBB menunjukkan perbaikan sel yaitu berkurangnya degenerasi. Hal ini menunjukkan bahwa ekstrak kunyit putih tidak hanya mampu menurunkan kadar gula darah tetapi juga memperbaiki sel-sel yang rusak akibat dari diabetes.
Pengaruh faktor risiko pekerja pemanen kelapa sawit terhadap terjadinya keluhan musculoskeletal disorders (MSDS) di PT. Perkebunan Nusantara IV unit Kebun Meranti Paham -, Hartono; Simatupang, Mega Riama Sawitri Br; Lina, Juliana; Bukit, Rosmeri br; Muharraran, Firdha
Jurnal Kesmas Prima Indonesia Vol. 7 No. 2 (2023): Edisi Juli
Publisher : Program Studi Sarjana Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jkpi.v7i2.4161

Abstract

Musculoskeletal Disorders (MSDs) are the most common occupational diseases that occur in the working population. The purpose of this study was to determine the effect of risk factors between age, workload, smoking habits and years of service of oil palm harvesters on the occurrence of musculoskeletal disorders. This study used an analytical survey method using a cross sectional design. The research sample is the entire population studied, namely 50 respondents at PT. Perkebunan Nusantara IV Meranti Paham Plantation Unit. The sampling technique used in this study is a total sampling technique where the number of samples is the same as the population. Data was collected using a Nordic Body Map (NBM) questionnaire. The analysis used was univariate, bivariate (Chi-square test) and multivariate analysis. The results of the bivariate analysis showed that there was a strong relationship between age and complaints of musculoskeletal disorders and the results also showed that there was a strong relationship between years of service and complaints of musculoskeletal disorders. The results of the multivariate analysis of the most dominant variable affecting musculoskeletal complaints were years of service after controlling for the age variable. So it was concluded that there was an influence between age and tenure with complaints of musculoskeletal disorders in oil palm harvesters. The most dominant factor for musculoskeletal complaints is years of service.
Profil Klinis Tonsilitis Pada Anak di Rumah Sakit Royal Prima Tahun 2023-2025 Praysela, Praysela; Lister, Clarissa; Lina, Juliana
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i11.62412

Abstract

Tonsillitis is one of the most common ENT disorders in children and may affect growth and overall quality of life. This study aimed to describe the clinical profile of pediatric tonsillitis patients at Royal Prima Hospital during 2023–2025. A retrospective descriptive observational design was used, involving 60 medical records that met the inclusion criteria. The results showed that the highest proportion of patients was aged 13–18 years (63.3%), with males being slightly more dominant (51.7%). Most patients had a normal nutritional status (70%), and the most frequent chief complaint was painful swallowing (58.3%). Physical examination revealed tonsillar enlargement predominantly at grade T3-T3 (55%). Chronic tonsillitis was more prevalent (66.7%) than acute tonsillitis (33.3%). Operative treatment was more commonly performed (55%) compared to medical therapy (45%). In conclusion, chronic tonsillitis remains a significant health issue in children, emphasizing the need for appropriate management to prevent complications and improve patient well-being.
Co-Authors Adek Amansyah Amanda, Carissa Anggraini, Sari Ayub, Edwar Br Sembiring, Emelia Putri Bukit, Rosmeri Br Dewi, Tani Sindy Safira Dwi Putri, Nabila Edlin, Edlin Edy Fachrial Fadillah, Qori Fernando Fernando, Fernando Fibrini, Dewi Fiska Maya Wardhani Fitriani, Anche Pratiwi Harmileni Hartono Hasibuan, Ahmad Hasanuddin Hasibuan, Selly Rahmadiah Hutapea, Jhonson Hutapea, Risma Ronauli Hyachinta, Izdihar Putri irza Haicha Pratama Iskandar, Ari Rahman Ivonne, Ivonne Johnson Hutapea lister , Clarissa Lister, Clarissa Loren, Jeff Masdalena, Masdalena Muchtar, Muhammad Arafat Muharraran, Firdha Mukti, Ade Indra Mutia, Maya Sari Nadapdap, Marshall Jeremia Nasution, Masdalena Nasution, Prenan Dito Perdana Nasution, Tamimi Badzlina Nazara, Novita Mirna Sari Novita, Cut Elvira Pasaribu, Rigal Arizki Praysela, Praysela Purwoko, Heri Putri Hyachinta, Izdihar Putri, Nabila Dwi Rahmadiah Hasibuan, Selly Reh Malem br Karo Rosari, Carolina Yosita Cahya Simatupang, Mega Riama Sawitri Br Sintya, Inda Dhea Sitorus, Teresya Nova Stefenie, Stefenie Surbakti, Betharia Lorenza Br Theresia, Yohani Thirza, Repi Ivena Tiswan, Jiad Hanan Wardhani, Fiska Maya Widya Yanti Sihotang Wijaya, Johana Fransiska Yumardika, Deza Yunata, Kianie Engaline Zahira, Niza Zaluchu, Sarah Oculi