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Etha Rambung
Universitas Ciputra
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : Human Care Journal

 1 
ELECTRIC CIGARETTES’S EFFECT TO THE MDA LEVELS IN BLOOD OF WISTAR RAT Etha Rambung
HUMAN CARE JOURNAL Vol 5, No 1 (2020): Human Care Journal
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v5i1.636

Abstract

The use of electronic cigarettes (e-cigarettes) has spread widely and increased dramatically among young people aroud the world. Variations in product design, taste, and marketing patterns increase the young people's interest in electronic cigarettes. Even many electric cigarettes are sold in shoppinng cebters and online, so they are easy to reach by teenagers. This study aims to analyze oxidative stress due to exposure to e-cigarettes by assessing the difference in blood MDA levels in the control and treatment groups. The method used is the Posttest Only Control Group Design. Thirty two male wistar rats divided into four treatments goups: K1 (SC (-), EE (-)), K2 (SC (-), EE(-)), P1 (SC(-),  EE (+) 15 times), and P2 (SC (-), EE (+) 30 times). The treatment is given for 5 minutes/ day for 50 days. Termination was carried out on the 50th day using ketamine. Intracardial blood sampling for examination of MDA levels by the TBARS method. The data obtained were tested by Kruskal Wallis with a significance of p <0.05. MDA blood levels in P2 were significantly higher than P1 (p =0,035), K2 (p =0,001) and K1 (p =0,001). This study shows that e-cigarettes can cause oxidative stress in experimental animals.
Co-Authors Abednego Nugraha Agnes Atmajaya Ang, Samantha Debora Angelarita Djami Raga Atalya Riawani Iring Aurelius, Vincent Azka Nadya Mifta Bambang Wirjatmadi Banjarnahor, Dharma Putra P. Binti, Carlos Gracia Supriantono Budi, Stephanie Laurensia Cempaka Harsa Sekarputri Christiani, Natalia Christine, Catarina Lilian Cindy Clara Sari Denys Putra Alim Dyah Kusuma Wardhani Elizabeth Sulastri Nugraheni Erik Jaya Gunawan Exantie Megaputri Jezua Ferdinand Aprianto Tannus Ferdinandus, David Fransisca Romana Titis Suniati Glory Ta’bi Palloan Gusto B. Yakobus Messakh Gusto Benyamin Messakh Hanna Tabita Hasianna Silitonga Hebert Adrianto Hudi Winarso I Made Irham Muhammad Imelda Ritunga Irene Sisilia Filipin Nggebu Janice Valencia Jemima Lewi Santoso Kaka, Wilhelmus Alvin Karmila Ayu Wardani Keith Justine Thiotansen Lindarto, Wira Widjaya Lukas, Dwi Lily Melania Rahadiyanti Mellyanawati Mellyanawati Mesakh, Billy Daniel Minarni Wartiningsih Najmul Laila Natalia Yuwono Ni Njoman Juliasih Novian Budi Santoso Nurul Illahi Muhammad Risha Oki Krisbianto Pangemanan, Fransisca Suyanto Panggabean, Ronald Torang Marsahala Priangga Adi Wiratama Rio Ferdinand, Gede Romauli Nainggolan Ronald Torang Marsahala Panggabean Salmon Charles P. T Siahaan Santosa, Rahajoe Imam Sheyoputri, Rytney Electra Siahaan, Salmon Charles Siahaan, Salmon Charles P.T. Siusanto Hadi Stefani Nurhadi Tannus, Ferdinand Aprianto Ulhaq, Aura Dhiya Wardani, Karmila Ayu Xena, Leora Esther