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All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Berkala Ilmu Kesehatan Kulit dan Kelamin The Indonesian Biomedical Journal Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Herb-Medicine Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Health and Medical Journal Jurnal Health Sains JOURNAL LA MEDIHEALTICO Journal Research of Social Science, Economics, and Management
Triasari Oktavriana
Department Of Dermatology & Venereology, Faculty Of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Profile of Skin Diseases in The Ederley at Nursing House Surakarta Mawardi, Prasetyadi; Oktavriana, Triasari; Murastami, Ammarilis; Murasmita, Alamanda; Pradestine, Sesia; Esa Putri, Osdatilla Esa; Lidjaja, Lifesia Natali; Alia, Vrenda; Kusumasari, Nila
Health and Medical Journal Vol 7, No 1 (2025): HEME January 2025
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v7i1.1640

Abstract

Background: The elderly population has been rapidly increasing over the past few decades. In Indonesia, the percentage of elderly residents is 8.75% of the total population. Aging is an unavoidable process, but it requires care to ensure a good quality of life for the elderly. One of the issues affecting the quality of life in the elderly is skin aging. Skin aging causes various complaints, especially itching or pruritus, which can reduce the quality of life for the elderly. Knowledge of the pathophysiology of skin diseases and skin aging, as well as the factors that affect them, particularly skin hydration, is necessary. This research is expected to be beneficial for medical professionals as well as family members of the elderly. The elderly residents at Wreda Griya PMI Peduli and Aisyiyah Nursing Home come from various regions and economic backgrounds. Therefore, the researchers consider the nursing home to be an appropriate place to conduct this study, as it can represent the elderly population from diverse backgrounds across Indonesia.Objective: This study aims to analyze the various skin disease profiles at the Griya PMI Peduli and Aisyiyah nursing homes in the city of Surakarta. Methods: This type of research is a survey using an observational study method with a descriptive design. Results: There were a total of 45 subjects at the Wreda PMI Peduli and Aisyiyah Nursing Home in Surakarta. Among them, 34 subjects had skin complaints, while 11 subjects were excluded because they did not have any skin complaints (7 subjects) or were uncooperative (4 subjects). The most common diagnosis was xerosis cutis (53%). The majority of patients did not have comorbidities (65%), with the most common comorbidity being hypertension (26%). Conclusion: The results of this study indicate that all the main skin complaints among the elderly at Panti Wreda in Kota Surakarta were dominated by itching or pruritus, with xerosis cutis being the primary etiology of pruritus in the elderly subjects of the study, accounting for 53%.
Phototherapy for Treating Chronic Spontaneous Urticaria Widyastuti, Zilpa; Oktavriana, Triasari
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 2 (2025): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikkk.V37.2.2025.147-152

Abstract

Background: Chronic spontaneous urticaria (CSU) is a disease characterized by the onset of wheals, angioedema and/or both for more than 6 weeks. The clinical characteristics of CSU include wheals and flares that are erythematous or skin- colored. The most frequently used medical therapy is second-generation H1 antihistamines followed by first-generation H1 antihistamines. CSU is currently treated with phototherapy utilizing narrowband ultraviolet B (NB-UVB). Case: A 36-year-old woman presented to the Dermatology and Venereology Outpatient Clinic of DR. Moewardi Hospital, Surakarta, with itchy reddish bumps all over her body since 6 months ago. A dermatology examination obtained multiple erythematous-based urticaria varying in size on her anterior and posterior trunks. We treated this patient with a combination of antihistamines and NB-UVB phototherapy at 200 mJ/cm2 weekly for a month. Significant clinical improvement was observed at week 4 of therapy. Discussion: In the treatment of chronic spontaneous urticaria, NB-UVB phototherapy serves as an adjuvant therapy. It acts as a suppressor of the systemic immune response which reduces the release of histamines and pro-inflammatory mediators, prevents mast cell apoptosis in the dermis, and regulates Th1 as well as Th2. The dose may start at 200 mJ/cm2 then increase by 10-20% for each visit. Conclusion: The combination of antihistamines and NB-UVB has a significant effect on treating chronic spontaneous urticaria. 
Clinical Manifestations and Prognosis Factors in Severe Cutaneous Adverse Drug Reaction (Scadr) Oktavriana, Triasari; Lauda, Benedikta; Putri, Osdatilla Esa
Jurnal Health Sains Vol. 6 No. 8 (2025): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v6i8.2674

Abstract

Severe Cutaneous adverse drug reaction (SCADR) is a severe skin reaction due to the use of drugs that can be life-threatening. This article describes the clinical manifestations and prognosis factors that affect SCADR patients. The most common types of SCADR were Stevens-Johnson Syndrome (SSJ) and Toxic Epidermal Necrolysis (TEN). The drugs that most often trigger are antibiotics and anticonvulsants. The main clinical manifestations include erythematosa skin lesions, epidermal necrolysis, and mucosal involvement. Significant prognosis factors include the extent of the affected skin area, internal organ involvement, and SCORTEN score. Patients with high SCORTEN scores have a greater risk of mortality. Early treatment and discontinuation of trigger drugs are key factors in improving clinical outcomes. The conclusion is early recognition of clinical manifestations of SCADR as well as assessment of prognosis factors can be helpful in patient management and reduce the risk of serious complications. The study also highlights the importance of educating medical personnel in detecting and managing severe drug reactions.
Profile And Risk Factors of Stevens Johnson Syndrome–Toxic Epidermal Necrolysis on Adult Patients in Dr. Moewardi General Hospital Surakarta from January 2019 – December 2022 Putri, Osdatilla Esa; Oktavriana, Triasari; Octarica, Stella Gracia; Anandita, Benedikta Lauda; Pradestine, Sesia; Oktaviani, Trya
Health and Medical Journal Vol 6, No 2 (2024): HEME May 2024
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v6i2.1517

Abstract

Background: Steven Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are acute and life-threatening skin diseases, commonly induced by medications. Study on SJS/TEN in Indonesia was still limited, hence knowledge about the profile and risk factors of SJS/TEN patients is still required to provide appropriate management and reduce patient mortality rate. This study aimed to determine the profile and risk factors of adult SJS/TEN patients in the inpatient installation of RSDM Surakarta. Methods: We conducted a cross sectional study using secondary data from medical records of SJS/TEN patients at the inpatient installation of Dr. Moewardi hospital, Surakarta from 2019 – 2022. Correlation tests on characteristics, comorbidity with length of stay (LoS) and discharge status were analyzed. Results: Of the total 147,531 inpatients, 35 (0.02%) of them were diagnosed with SJS/TEN, dominated by females (57.14%) with the mean  of 45.74 years old.  Most subjects were diagnosed with SJS (48.57%), followed by SJS/TEN (40.0%) and TEN (11.43%). The mean LoS was  ± 8 days. Most subjects were discharged alive (85.71%). Paracetamol was the most common causative drug (25.71%), followed by cefadroxil (11.43%). Acute kidney injury (AKI) was the most common comorbidity (14.29%, p = 0.040). Spearman Rank test obtained no correlation between comorbidities and LoS (r = 0.028 ; p = 0.842) as well as discharge status (r = 0.063 ; p = 0.651). Conclusion: SJS/TEN is rare case with high mortality rate. Patients’ comorbidities have a very weak correlation with LoS and discharge status. Initial knowledge of the patient’s profile and risk factors including comorbidity and causative drugs can optimise comprehensive therapy for SJS/TEN patients.
Co-Authors Achmad Satya Negara Agnes Sri Siswati Alia, Vrenda Ambar Mudigdo Ambar Mudigdo Ambar Mudigdo Anandita, Benedikta Lauda Arie Kusumawardani Ayu Kusuma Dewi Bobby Febrianto Budi Eko Prasetyorini Dharmawan, Nugrohoaji Dita Eka Novriana Dita Eka Novriana Ellistasari, Endra Yustin Ervina Rosmarwati Esa Putri, Osdatilla Esa Fatimah Fitriani Fiska Rosita Fitranto Arjadi Irawanto, Muhammad Eko Irene Jessica Pinarsinta Harahap Ismiralda Oke Putranti Ivani, Ivani Kariosentono, Harijono Kristiana Etnawati Kusumawardani, Arie Lauda, Benedikta Lidjaja, Lifesia Natali Murasmita, Alamanda Murastami, Ammarilis Nathania Amelinda Nila Kusumasari Niluh Wijayanti Noviani, Laura Octarica, Stella Gracia Octavia Permata Sari Oktaviani, Trya Pradestine, Sesia Prasetyadi Mawardi Putri Oktriana Rachman Putri, Osdatilla Esa Putti Fatiharani Dewi Rahma, Alfina Rosmarwati, Ervina Suci Widhiati Thianti Sylviningrum Widhiati, Suci Widyastuti, Zilpa