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All Journal Folia Medica Indonesiana Indonesian Journal of Tropical and Infectious Disease Dental Journal (Majalah Kedokteran Gigi) Jurnal Ilmu Kedokteran dan Kesehatan JPPM (Jurnal Pengabdian dan Pemberdayaan Masyarakat) Biomolecular and Health Science Journal Conservative Dentistry Journal Indonesian Journal of Dental Medicine Indian Journal of Forensic Medicine & Toxicology

Agung Sosiawan

Faculty Of Dental Medicine Universitas Airlangga Surabaya – Indonesia

Author-ID : 2019258

Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Dentistry Earth & Planetary Sciences Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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The Use of Artificial Intelligence in New Normal Era Against Pandemic COVID-19 in the Field of Health Services Dian Agustin Wahjuningrum; Fery Setiawan; Setyabudi; Heni Puspitasari; Ahmad Yudianto; Agung Sosiawan; Arif Rahman Nurdianto; Swadheena Patro
Conservative Dentistry Journal Vol. 12 No. 1 (2022): January-June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v12i1.2022.12-19

Background: Indonesia is currently experiencing Coronavirus Disease-19 (COVID-19) pandemic which affects all sectors of life, therefore Indonesia is starting to prepare for New Normal era, including in health care sector. COVID-19 was previously known as novel Coronavirus Disease-19 (nCoV-19), where World Health Organization (WHO) declared it as a global pandemic in March 2020. New Normal era is an era of coexistence with COVID-19, resulting in new habits that were rarely or never practiced before. One practice that can be applied in health care sector is to use Artificial Intelligence (AI) to treat COVID-19 patients to prevent casualties for health workers. Health care providers are prone to contract aerosol and droplet transmission while treating patients, resulting in cytokine storm, acute respiratory distress syndrome (ARDS), and acute lung injury (ALI), which leads to death. Purpose: This mini review study used to explain the using of artificial intelligence in the new normal era against pandemic COVID-19 in the field of health services. Reviews: This pandemic COVID-19 restricts all of the communication between person to person. It also challenged the health service sector because the health service sector is the first line to combat the COVID-19. It is now popular to use artificial intelligence. This using can be used to help the health service sector in combating the COVID-19 pandemic especially in this new normal era. Conclusion: COVID-19 pandemic affects all aspects of life, especially health care sector, therefore AI use is important to prevent the deaths of health workers because of this pandemic.

Estimation of children’s age based on dentition via panoramic radiography in Surabaya, Indonesia Agung Sosiawan; An'nisaa Chusida; Beshlina Fitri Widayanti Roosyanto Prakoeswa; Arofi Kurniawan; Maria Istiqomah Marini; Beta Novia Rizky; Tito Krisna Gianosa; Najminoor Ramadhani Ridlo; Mumtaz Ramadhani Putra Pesat Gatra; Aspalilah Alias
Dental Journal Vol. 55 No. 3 (2022): September 2022
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v55.i3.p161-164

Background: Age may be estimated using tooth eruption sequence and/or calcification stage. Because many factors may affect the time of eruption, the tooth calcification stage shows higher accuracy than the time of tooth eruption. Demirjian’s and Willems’ methods have been most commonly used for dental age estimation. Both Willems and Demirjian use the calcification stage as an indicator. Studies comparing these methods have shown varied results, as they have been performed on different populations. Purpose: This paper aims to analyse the estimation of children's age based on dentition via panoramic radiography in Surabaya, Indonesia. Methods: This is a cross-sectional study using a purposive sampling method. One hundred digital panoramic radiographs of children between 6 and 15 years that match the inclusion criteria from the Airlangga University dental hospital in Surabaya, Indonesia were evaluated. One researcher analysed estimated dental age (EDA) three times in a one-week time-lapse using Demirjian’s and Willems’ methods. Statistical analysis was carried out using a Paired t-test and Wilcoxon signed-rank test. EDA was calculated using both Demirjian’s and Willems’ methods. Results: The mean chronological age (CA) was 10.57 ± 2.70 for males and 10.73 ± 2.84 for females. The mean difference between CA and EDA using the Demirjian and Willems methods was -0.57 ± 1.17 and 0.10 ± 0.96 for males and 0.58 ± 1.40 and 0.44 ± 0.94 for females. Conclusion: The results suggest that Willems’ method is more precise than Demirjian’s method in males and females and more suitable for children in Surabaya, Indonesia.

A case study of informed consent in Indonesian Law Number 29, 2004 Agung Sosiawan; Vera Rimbawani Sushanty; Dian Agustin Wahjuningrum; Fery Setiawan
Dental Journal Vol. 56 No. 1 (2023): March 2023
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i1.p1-6

Background: Informed consent is an agreement between the doctor/the provider of medical services and the patient/the recipient of medical services. This relationship between these parties has changed from a paternalistic to a contractual relationship due to technological shifts. Doctors are obliged to notify the patient of all the risks and benefits of a procedure while respecting their autonomy by not intervening the decision-making process. This article will look at three government and academic hospitals in Surabaya, as informed consent has to be practiced in all medical settings. Purpose: This study aims to review the role of informed consent according to Law Number 29, 2004. Review: This study aims to discuss the characteristics of informed consent under Law Number 29, 2004, because there are too few articles addressing this issue. It also explains the roles of the patient and the doctor/dentist in informed consent according to this piece of legislation. Conclusion: According to Article 184, informed consent provides vital evidence that can be used to hold doctors and dentists legally accountable because it contains information about standard operating procedures (SOPs) that medical professionals are legally required to follow. Guidelines for informed consent are given in Law Number 29, 2004, Article 45, paragraph 2.

Pola Kombinasi Genotip Gen BMP2 Rs235768 A>T Pada Kejadian Celah Bibir Dan Atau Palatum Non Sindromik Agung Sosiawan; Mala Kurniati; RM Coen Pramono
Jurnal Ilmu Kedokteran dan Kesehatan Vol 9, No 4 (2022): Volume 9 Nomor 4
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v9i4.8586

Celah bibir dengan atau tanpa palatum (CB/P) adalah suatu kondisi deformitas orofasial yaitu terbentuknya pembukaan atau celah yang tidak wajar pada bibir atau palatum. Sekitar 70% CB/P yang terjadi di populasi adalah non sindromik (NS). Tujuan penelitian ini yaitu mengetahui pola kombinasi genotip gen BMP2 rs235768 A>T pada keluarga pasien CB/P. Sampel DNA yang berhasil diamplifikasi dan direstriksi sebanyak 5 sampel keluarga yang terdiri dari ayah, ibu dan anak dengan kelainan CB/P. Berdasarkan analisis dengan menggunakan enzim restriksi dan software program Finch TV dan Bioedit, penelitian ini mengidentifikasi adanya perubahan basa A menjadi basa T yang merupakan missense mutasi (Serin – Arginin/TCA-TCT). Dari hasil pemetaan pada gen BMP2 rs235768 A>T menunjukkan kelima keluarga memiliki kombinasi yang berbeda-beda. Hal yang menarik pada keluarga ke - 3, kombinasi ayah bergenotip AA (Homozigot/common) dan ibu bergenotip TT (Homozigot/uncommon), memiliki anak ke -3 bergenotip AA (Homozigot/common) dengan kelainan CP (Palatoschizis incomplete). Kombinasi genotip yang mungkin dapat terjadi pada anak dari keluarga 4 yaitu 50 % bergenotip AT (Heterozigot), 50% bergenotip TT (Homozigot/uncommon). Kejadian CB/P tidak hanya melibatkan satu faktor keturunan yang berasal dari satu atau kedua orang tua, tetapi suatu kondisi yang bersamaan. Kelainan CB/P yang terjadi pada anak perempuan, diprediksi risiko kekambuhan pada anak berikutnya jauh lebih tinggi.

The role of purple leaves extract (Graptophyllum Pictum (L.) Griff) on the number of fibroblasts and blood vessels in the socket after tooth extraction Atik Kurniawati; Yuli Dwi Kristanti; Naila Azifatur Rahmat; Yani Corvianindya Rahayu; Zainul Cholid; Agung Sosiawan
Dental Journal Vol. 57 No. 1 (2024): March
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i1.p56-61

Background: Tooth extraction is the process of removing teeth from the alveolus. It will leave a mark on the socket and surrounding soft tissue. One of the cells that plays an important role in the wound healing process after tooth extraction is fibroblasts. When an injury occurs, some blood vessels are damaged; therefore, new blood vessels need to form. Purple leaves extract could be an alternative treatment for wound healing after tooth extraction as it contains flavonoids, saponins, alkaloids, steroids, and tannins. Purpose: The study aimed to analyze the role of purple leaves extract on the increase in fibroblasts and blood vessels in the socket after tooth extraction in Wistar rats. Methods: The method used was a laboratory experiment with a post-test-only control group design. The samples used were 24 rats divided into two groups: the control group, which was given aquadest, and the treatment group, which was given 1.5 mL of purple leaves extract with 10% concentration by sondage. Tissue preparations were used to count fibroblasts, and blood vessels were counted and observed on the 3rd, 5th, and 7th days. Results: Statistical tests showed a significant difference in the number of fibroblasts and blood vessels between the control and treatment groups on days 3, 5, and 7. Conclusion: Purple leaves extract could increase the number of fibroblasts and blood vessels in the tooth socket after tooth extraction of Wistar rats.

ROLE OF BREAK CLUSTER REGION (BCR) - ABELSON MURINE LEUKIMIA (ABL) EXAMINATION IN CHRONIC MYELOGENOUS LEUKEMIA (CML) Sosiawan, Agung
Indonesian Journal of Tropical and Infectious Disease Vol. 5 No. 2 (2014)
Publisher : Institute of Topical Disease Universitas Airlangga

Chronic myelogenous leukemia (CML) is a clonal bone marrow stem cell disorder associated with a characteristic chromosomal translocation called the Philadelphia chromosome which caused a proliferation of mature granulocytes (neutrophils, eosinophils and basophils) and their precursors, increasing unregulated growth of predominantly myeloid cells in the bone marrow and its accumulation in the blood. As myeloproliferative disease, Chronic Myelogenous Leukemia or CML is a malignancy of the sixth-highest, reaching 15% of all blood malignancies in adults with an incidence of 1.1 per 100,000 population (Ugroseno, 2012). The CML diagnosis is made based on a presence of Philadelphia chromosome due to the existence of a reciprocal translocation of chromosomes 9 and chromosome 22 t (9.22), and raises the fusion of Break Cluster Region (BCR) gene of chromosome 22 on band q11 by Abelson Murine Leukemia (ABL). The fused BCR-ABL gene has BCR sequences of different length, so it produces a protein that has a different molecular weight. Despite having different length of BCR sequences, however, the length of fuses ABL gene sequence is constant. Associated with this different BCR sequence length are the three variations of the BCR-ABL gene fusion. The first variation is a Major Break Cluster (M-BCR), the BCR gene break is found in exon 2 in e13-E14 region. This type of CML is the fusion of BCR exon b2 or b3 to ABL exon a2, forming two major transcripts of the b2a2 or b3a2, which has a protein product with 210 kD weight or referred to as p210. The second variation is Minor BCR (m-BCR), which has e1a2 fusion. CML with BCR-ABL gene fusion of this type has a protein product with a molecular weight of 190 kDa or called p190. The third variation is micro-BCR (m-BCR), with BCR gene break between exons E19 and e20b that form mRNA transcripts e19a2, with BCR-ABL protein P230. This fused gene can be detected with qualitative multiplex PCR.

Educational Comic for Dental Caries Prevention in Kalijudan 1 Elementary School, Surabaya Sosiawan, Agung; Bramantoro, Taufan; Putri Gofur, Aisyah Rachmadani; Devina, Dida; Kumala Dewi, Ni Nyoman Astari
Indonesian Journal of Dental Medicine Vol. 2 No. 1 (2019): Indonesian Journal of Dental Medicine
Publisher : Faculty of Dental Medicine Universitas Airlangga

Background: Dental caries is one of the dental and oral diseases, and it is caused by S. mutans. Almost all humans have dental caries, and it is a burden disease in Indonesia. The prevalence of dental caries is 79.1% worldwide, and the prevalence of child dental caries in Indonesia was 92.6% in 2018. Purpose: To promote child dental health awareness in children through an educational comic. Methods: Educational comics were distributed directly to students of Kalijudan Elementary School. Tools and materials of the empowerment program: Stationery, Laptop/computer, Application to layout the comic. There are 13 teachers and 30 students involved in this program. The students were given pre-test before learned about dental health from educational comics. After receiving health education materials from the comics books, they were given post-test to measure the increasement of health knowledge. Pre and post test data were analyzed with Paired-T test. Results: The pre-test and post-test results of the empowerment program at Kalijudan 1 elementary school were 12.3 and 13.6, respectively. There was a 1.3 point increase. The significance value was 0.000 (p-Value < 0.05). This means that there was a significant difference in children's knowledge levels before and after they read the comic. Conclusion: The result showed that children have learned that dental and oral health affects physical activities.

Dental Health Physical Exercise (SKG) for Elderly Khotimah, Fridaniyanti Khusnul; Sosiawan, Agung; Santosa, Lintang Maudina; Sudiartha, Nancy Cynthia; Pande, I Ketut Brahma; Romadhona, Widya Rizky; Pangestika, Elvira Widya; Rachmaningayu, Ulyasari; Saputra, Benny; Amarilda, Faila Shofa; Priyanridania, Erika; Bramantoro, Taufan
Indonesian Journal of Dental Medicine Vol. 2 No. 1 (2019): Indonesian Journal of Dental Medicine
Publisher : Faculty of Dental Medicine Universitas Airlangga

Background: Late adulthood is an aging process characterized by a decrease in some bodily functions. Physical changes associated with late adulthood are musculoskeletal disorders, changes in the cardiovascular system, changes in the immune system, and changes in physical activity. Physical exercise is one of the ways to improve elderly' physical activities. An epidemiological study on elderly under Jagir Public Health Center coverage area reported that periodontitis and dental caries could lower physical performance in the elderly, lowering physical activity. Purpose: In consideration of theproblem in question, a promotive and preventive program is needed. The Dental Health Physical Exercise (SKG) program was expected to improve the overall physical condition of the elderly. Methods: The "Senam Kesehatan Gigi dan Mulut” took place on 19 July 2019 at Integrated Health Service Post for Elderly. Results: There were 26 elderly participated in physical exercise. 7.7% of them were not able to follow the exercise, and the remaining 92.3% were able to follow the exercise. Conclusion: 92.3% of 26 elderly were able to follow the exercise properly and correctly. However, the remaining 7.7% of them were not able to catch up with the physical exercise. In addition, most participants were able to perform 4 out of 5 movements criteria.

Preventing Dental Cavities with Mouth Rinsing Song for Elementary School Students, Sawahan District, Surabaya City Hutapea, Yohana Vita Melodi; Andiyani, Intan; Nuradiyah, Fanny; Yusticia, Ica; Hidayanto, Agung Ridwan; Pramita, Anggi; Fadila, Vivin Dwi; Syarifah, Indi Mazaya; Fatah, Rizki Amelia; Halim, Muhammad; Susanti, Dwi; Sosiawan, Agung
Indonesian Journal of Dental Medicine Vol. 2 No. 1 (2019): Indonesian Journal of Dental Medicine
Publisher : Faculty of Dental Medicine Universitas Airlangga

Background: Dental and oral health is one of the public health indicators. Dental and oral health problems decrease individual health function. A lack of mouth rinsing causes dental and oral health problems in children after consuming sweet food. Dental health promotion can help the children learn about mouth rinsing and encourage them to have it regularly. MisDent is an educational program about dental health designed for children. We demonstrated and promoted mouth rinsing to the students, especially after they confused sweet food. Purpose: To promote correct tooth brushing to children and help monitoring student's dental health partnering with the local public health center. Methods: The program used dental health promotion strategies Patemon 2 Elementary School. We evaluated the program as well. Results: About 60% of students at Petemon 2 Elementary School were able to answer the questions correctly, have mouth rinsing correctly, memorize the "REK KUMUR REK” song. Conclusion: "MisDent” involved the first and second-grade students of Patemon 2 Elementary School. The program was expected to help to educate the students about dental and oral health.

Strengthening Maternal Social Support and Promoting Child Dental and Oral Health Through SIKATIN (Tooth Brushing Reminder App) Sosiawan, Agung; Mahiswari, Diyang; Wardi, Ully Nafisah; Hadinata, Daniel; Anjani, Nindya Rizki; Roselle, Veronica Regina; Nugroho, Sepdhyo Wahyu; Ramadhani, Maya Eka; Rumokoi, Rauhansen Bosafino; Sholihah, Naimatus; Afidati, Yasinta Izzah
Indonesian Journal of Dental Medicine Vol. 3 No. 1 (2020): Indonesian Journal of Dental Medicine
Publisher : Faculty of Dental Medicine Universitas Airlangga

Background: Downloadable health applications are nothing new for the public. Smartphone use has been steadily increased in years, including increased smartphone use in mothers of kindergarten students in Made Urban Village, Surabaya. Therefore, smartphone applications can be effective media in promoting child dental and oral health. The prevalence of caries in Made Kindergarten was 95%, and it was concerning. Therefore, the SIKATIN app works byreminding mothers about tooth brushing schedules for their children and motivating them to pay extra care for children's dental and oral health. Purpose: Mothers are motivated to maintain their children's dental and oral health. Method: The empowerment program helped to promote the SIKATIN app use, and the evaluation was based on the total download.Results: 100% of mothers of kindergartners achieved all indicators of success. Conclusion: 100% of the mothers of kindergartners in Made Urban Village has downloaded the SIKATIN application.

Co-Authors Adla, Karina Awanis Afidati, Yasinta Izzah Ahmad Yudianto Ahmad Yudianto Alexander Patera Nugraha Amalia, Rovilla Amarilda, Faila Shofa Amit Bhardwaj An'nisaa Chusida Andiyani, Intan Andra Rizqiawan Andry Sentosa Anjani, Nindya Rizki Anjani, Nindya Rizqi Anuj Bhardwaj Ardyni Febri K Arif Rahman Nurdianto Arofi Kurniawan Aryo Dwipo Kusumo Aspalilah Alias Atik Kurniawati Aulia Ramadhani Azhar, Imam Safari Beshlina Fitri Widayanti Roosyanto Prakoeswa Beta Novia Rizky David Sontani Perdanakusuma Detalicia, Callista Gladys Fionna Devina, Dida Dhywinanda, Devin Elysia Dian Agustin Wahjuningrum Dini Parasila Dwi Susanti Fadila, Vivin Dwi Fajariana Fitriani Fatah, Rizki Amelia Fauzan Fauzan Fery Setiawan Fissando Yanuar Muhammad Giftania Nuri Susilo Gilang Rasuna Sabdho Wening Hadinata, Daniel Hari Basuki Notobroto Heni Puspitasari Hidayanto, Agung Ridwan Hutapea, Yohana Vita Melodi Imelda Kristina Sutrisno Ira Arundina Jordana, Jesslyn Kamilah, Tsaniya Karimah, Zalfa Khotimah, Fridaniyanti Khusnul Kratika Mishra Krissanti, Theresa Dian Kumala Dewi, Ni Nyoman Astari Kurniati, Mala Kuswanda, Crisna Tri Laisyaina, Defita Ayu Lutfi Malia Rossa Maharani, Gita Alethea Kristi Mahiswari, Diyang Mala Kurniati Mala Kurniati Margaret, Nola Maria Istiqomah Marini Muhammad Halim, Muhammad Mumtaz Ramadhani Putra Pesat Gatra Naila Azifatur Rahmat Najminoor Ramadhani Ridlo Ni Wayan Tirtaningsih Ninuk Hariyani Nugroho, Sepdhyo Wahyu Nuradiyah, Fanny Nurrezeki, Andi Adani Pande, I Ketut Brahma Pangestika, Elvira Widya Pramita, Anggi Pratama, Innocencio Kresna Priyanridania, Erika Putri Gofur, Aisyah Rachmadani R. Darmawan Setijanto Rachmaningayu, Ulyasari Rachmawati, Almira Ramadhani, Maya Eka Regina, Veronica Retno Palupi Retno Pudji Rahayu RM Coen Pramono RM Coen Pramono D Romadhona, Widya Rizky Roselle, Veronica Regina Rumokoi, Rauhansen Bosafino Salim, Jennifer Fiona Salsabila Maghfirani Santosa, Lintang Maudina Saputra, Benny Sembadani, Yuliana Merlindika Sengupta, Kaushik Setiyowati, Dini Setyabudi Setyabudi Sheetal Khandelwal Shivani Bhardwaj Sholihah, Naimatus Sholihah, Nimatus Sudiartha, Nancy Cynthia Swadheena Patro Syahdryani, Zhafira Putri Syarifah, Indi Mazaya Taufan Bramantoro Thomas Reynaldi Winanto Titiek Berniyanti Tito Krisna Gianosa Vera Rimbawani Sushanty Vita Ariesta Angesti Wardi, Ully Nafisah Widodo Widodo Yani Corvianindya Rahayu Yuli Dwi Kristanti Yusticia, Ica Zainul Cholid Zuhdi, Nadya Adina

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