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The Lungs: Anatomy, Function, Disorders, and Care Akram, Muhammad; Ahmed, Misbah; Umaru, Isaac John
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 2 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i2.5277

Abstract

The lungs play a crucial role in the respiratory system, facilitating oxygen intake and carbon dioxide removal. This article explores lung anatomy, including the differences between the right and left lungs, and details their function in gas exchange. It also highlights common lung disorders such as asthma, COPD, and lung cancer, along with their symptoms, diagnostic tests, and treatments. Additionally, it provides essential tips for maintaining lung health, such as quitting smoking, exercising, and staying hydrated. Understanding lung function and care is vital for overall well-being and disease prevention.
Psychological Framework of Early Emotional Bonds Akram, Muhammad; Abbas, Sabahat; Umaru, Isaac John
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 2 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i2.5304

Abstract

The attachment theory suggests that the parental-child relationship is the building block for future relationship patterns and immediate security and comfort. A securely attached child will likely have healthy relationships as an adult, with better emotional awareness, empathy, and capacity to create long-term love relationships. On the other hand, insecurely attached children may go on to experience issues with attachment into adulthood, leading to relationship difficulties, emotional dysregulation, and greater risk of mental health difficulties such as personality disorders, anxiety, and depression. Additionally, it has been proven that the attachment system itself is also dynamic and changes depending on a wide range of relational and environmental circumstances. The type of attachment relationships can be influenced by a variety of factors, such as parenting style, societal context, cultural expectations, and even the occurrence of outside stressors like trauma or divorce. For instance, therapies that foster secure attachment can effectively decrease the negative impacts of early trauma and adversity and allow children to be resilient.
Advancements in Epilepsy Treatment: Challenges, Innovations, and Social Impacts on Patients Akram, Muhammad; Aslam, Muhammad Tayyab; Umaru, Isaac John
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 2 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i2.5327

Abstract

Epilepsy-related seizures can range greatly, from focal seizures that can impact certain brain areas to widespread tonic-clonic seizures. Although the exact origin of epilepsy is sometimes unknown, the underlying reasons are many and include genetic factors, brain damage, infections, stroke, tumors, and developmental abnormalities. The goal of both pharmaceutical and non-pharmacological treatments for epilepsy is to avoid seizures. With the aim of controlling seizures, antiepileptic medications (AEDs) are the first line of treatment for the majority of patients. However, about one-third of individuals with epilepsy suffer from drug-resistant seizures, which can cause cognitive, psychological, and social issues and have a significant impact on their quality of life. In these cases, alternative treatments like deep brain stimulation, vagus nerve stimulation, ketogenic diets, and surgery may be considered. New insights into the genetic and molecular mechanisms underlying epilepsy have created opportunities for personalized medicine, allowing for more focused therapeutic approaches. New treatment approaches have been made possible by the discovery of certain genetic mutations, changed ion channel function, and neuroinflammation in some forms of epilepsy. Even with these developments, there are still obstacles in the way of attaining ideal seizure control and raising epileptic patients' quality of life. Because individuals with epilepsy may experience stigmatization, discrimination, and obstacles to social integration, work, and education, the illness also has significant social ramifications. To improve outcomes for individuals with epilepsy, comprehensive care models, enhanced diagnostic technologies, and public awareness campaigns are essential. Additionally, the burden that epilepsy causes on people and society may be lessened with continued study into the neurobiological processes of seizures and the creation of more potent therapies.
The Growing Impact of Telemedicine in Modern Healthcare Akram, Muhammad; Khan, Alam Afroz Urooj; Umaru, Isaac John; Shahid, Isbah
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 2 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i2.5422

Abstract

Telemedicine employs technology to facilitate remote consultations and treatments, fundamentally changing healthcare practices. Its application increased significantly during the COVID-19 pandemic, enhancing healthcare access, reducing costs, and facilitating the management of chronic diseases and mental health issues. While offering distinct benefits, such as greater efficiency and enhanced accessibility, telemedicine also poses challenges, including technological hurdles, privacy issues, and legal restrictions. Emerging innovations such as artificial intelligence, smart gadgets, and interconnected health systems position telemedicine to become an essential element of contemporary healthcare. Targeted policy and infrastructure initiatives are crucial to promote equitable and effective use.
Persistent Threat of Lassa Fever in Nigeria: Epidemiology, Challenges, and Strategies for Effective Management Akafa, Tensaba Andes; John, Artu Ishishen; Oladele, Gloria Omonefe; Umaru, Isaac John
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 2 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i2.5517

Abstract

Lassa fever is a viral hemorrhagic disease that poses a significant public health threat in Nigeria and West Africa. This review assesses the epidemiological trends, health impacts, and socioeconomic consequences of Lassa fever in Nigeria while proposing strategies for effective management and prevention. The natural reservoir of the Lassa virus, the multimammate rat (Mastomys natalensis), is prevalent in Nigerian households, facilitating transmission through direct contact with the rodents or their excreta, which often contaminates food. Consumption of these rats as a delicacy further exacerbates the risk. Current epidemiological data reveal that Lassa fever is endemic in Nigeria, with seasonal outbreaks primarily occurring in the dry season. The Nigeria Centre for Disease Control and Prevention (NCDC) reported 80 deaths and 413 confirmed cases across 11 states during Epidemiological Week 6 of 2025, with Taraba, Ondo, Bauchi, and Edo states accounting for over 73% of these cases. The Case Fatality Rate (CFR) for Lassa fever has risen to 19.4% in 2025, compared to 17.5% in 2024, likely due to factors such as underreporting and limited healthcare access. Notably, the CFR can range from 1% to 50%, influenced by healthcare access and early detection. The urgent nature of Lassa fever necessitates enhanced public health interventions, community education, and effective surveillance systems to mitigate its incidence and socioeconomic impact in Nigeria, thereby contributing to the achievement of Sustainable Development Goal target 3.3 to eliminate epidemics of Lassa fever and other neglected tropical diseases by 2030.
Restoring, Repairing, and Regenerating Tissues through Biomaterials, Cells, Scaffolds, and Innovative Technologies Akram, Muhammad; Umaru, Isaac John; Mahmood, Abid; Hasan, Mohammed Khudhair; Abdulghafoor, Hind A.; Khan, Fahad Said; Ozdemir, Fethi Ahmet; Sołowski, Gaweł; Ali, Jaouher Ben
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 2 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i2.5578

Abstract

Tissue engineering and regenerative medicine (TERM) is an innovative area of research and development that includes biomaterials, cells, scaffolds, scaffolding structures, and even bioactive substances to restore, repair or regenerate damaged tissues along with organs. The scope of synthetic skin expansion has now progressed to engineering kidneys, hearts, and lungs. Use of stem cell therapies or extracellular matrices for organ healing and regeneration are other; notable shifts toward tissue engineering paradigm are towards healing adn regeneration rather than the development of reconstructive surgery. While research has shown promise, there are still concerns regarding its clinical use citing complications such as immune system rejection of newly implanted tissues, ethical issues and the economical creation of engineered tissues. The efforts being made in Asia demonstrate emerging potential in TERM. Enhanced collaboration across disciplines is essential to pave new ways towards realizing current restrictions and bold influencing ideas alongside breakthroughs.
Understanding Gastritis: Causes, Symptoms, Diagnosis, and Management Akram, Muhammad; Mahmood, Abid; Umaru, Isaac John; Hasan, Mohammed Khudhair; Abdulghafoor, Hind A.; Khan, Fahad Said; Ozdemir, Fethi Ahmet; Sołowski, Gaweł; Ali, Jaouher Ben; Al-Musawi, Jehan Mohammad
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 2 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i2.5580

Abstract

One such common disorder is gastritis, that is bound to cause acute or chronic inflammation of the stomach lining. It is primarily caused due to the long duration use of NSAIDs, Helicobacter pylori infection or many other reasons. Alcohol consumption, stress, bile reflux and some immunological processes also play a role in causing gastritis. While some relatives remain asymptomatic, most relatives experience symptoms such as epigastric discomfort, vomiting, and, in some cases, gastrointestinal bleeding. H. Pylori detection, endoscopic examination, and histopathology are the primary techniques for diagnosing gastritis. Another method of treatment is the use of proton pump inhibitors along with lifestyle changes, or antibiotics. Gastritis and its symptoms can be mitigated by employing primary prevention strategies like proactively treating H. Pylori infections or reducing NSAIDs consumption.
Marburg Virus Disease: Epidemiology, Transmission, and Global Health Implications Akram, Muhammad; Mahmood, Abid; Umaru, Isaac John; Hasan, Mohammed Khudhair; Abdulghafoor, Hind A.; Khan, Fahad Said; Ozdemir, Fethi Ahmet; Sołowski, Gaweł; Ali, Jaouher Ben; Al-Musawi, Jehan Mohammad
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 2 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i2.5816

Abstract

Marburg virus disease (MVD), a severe viral hemorrhagic fever, was first identified in 1967 following simultaneous outbreaks in Marburg and Frankfurt, Germany, and Belgrade, Serbia. The initial cases were linked to laboratory exposure to African green monkeys (Chlorocebus aethiops) imported from Uganda for scientific research. Since then, sporadic cases and outbreaks have been reported across sub-Saharan Africa, particularly in Angola, Uganda, the Democratic Republic of the Congo, and, more recently, in West African countries such as Ghana. Human-to-human transmission occurs through direct contact with the blood, secretions, organs, or other bodily fluids of infected individuals, as well as via contaminated materials like bedding and medical equipment. The incubation period ranges from 2 to 21 days, after which patients typically present with hemorrhagic manifestations, shock, and multiorgan failure. Currently, there is no approved antiviral treatment, and management is limited to supportive care, including fluid resuscitation, electrolyte balance, oxygen therapy, and treatment of secondary infections. Early diagnosis, case isolation, contact tracing, and stringent infection control measures are essential to containing outbreaks. Due to its high case-fatality rate, potential for epidemic spread, and lack of licensed therapeutics or vaccines, MVD is designated a priority pathogen by the World Health Organization (WHO). In the context of increasing global attention to emerging and re-emerging infectious diseases, this review emphasizes the urgent need for investment in health system strengthening, improved diagnostic infrastructure, and the acceleration of vaccine and therapeutic development to mitigate future outbreaks.
The Psychology of Loneliness: Understanding Its Causes, Effects, and Paths to Healing Akram, Muhammad; Umaru, Isaac John; Aslam, Nosheen; Rashid, Abid; Hasan, Mohammed Khudhair; Abdulghafoor, Hind A.; Khan, Fahad Said; Ozdemir, Fethi Ahmet; Sołowski, Gaweł; Al-Musawi, Jehan Mohammed; Mahmood, Abid
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 3 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i3.6349

Abstract

Loneliness is a deeply personal and multifaceted emotional state that affects millions of individuals across all ages, genders, and cultural backgrounds. Often misunderstood as a temporary feeling, loneliness can have serious implications for both mental and physical health, contributing to conditions such as depression, anxiety, and cognitive decline. This article explores the psychological underpinnings of loneliness, examining how it influences emotional well-being, thought processes, and behavior. It also analyzes the broader social and cultural dynamics, such as digital disconnection, urbanization, and changing family structures that have contributed to its growing prevalence in the modern world. In response, the article discusses a range of evidence-based approaches to addressing loneliness, including public awareness initiatives, therapeutic interventions focused on social reengagement, and lifestyle adjustments aimed at fostering meaningful connections. By highlighting these strategies, the article seeks not only to demystify the experience of loneliness but also to promote resilience and recovery, offering a hopeful perspective on overcoming this often-invisible emotional struggle.
Effect of Methanol Stem Bark Extract of Annona senegalensis as an Antibacterial Agent and on Liver Enzyme Markers in Diethyl Nitrosamine-Induced Hepatocellular Carcinoma in Rats Umaru, Isaac John; Efongwa, Emmanuel; Omolara, Mosugu Ovayoza; Okang, Ogar Fonne; Akem, Ingwu Joseph; Tansaba, Akafa Andes; Philip, Shadrach; Frank, Otashu Kenneth
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 3 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i3.7361

Abstract

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide, frequently linked to exposure to chemical carcinogens such as diethylnitrosamine (DEN). Medicinal plants have emerged as promising sources of bioactive compounds with potential anticancer and antimicrobial properties. This study evaluated the therapeutic potential of methanol stem-bark extract of Annona senegalensis against DEN-induced hepatocellular carcinoma and selected bacterial pathogens. Fifty-four male albino rats were allocated into six groups, with hepatocarcinogenesis induced by DEN, followed by a 14-day treatment with varying doses of the extract. Hepatoprotective effects were assessed using liver enzyme markers and serum protein levels, while antibacterial activity was determined via disc diffusion assays against Staphylococcus aureus and Escherichia coli. Results demonstrated that the extract significantly reduced liver enzyme levels (ALT, AST, ALP) and improved serum proteins (total protein and albumin) at higher doses (400 and 600 mg/kg), indicating hepatoprotective potential. Bilirubin levels also improved, suggesting reduced liver stress. Antibacterial evaluation revealed dose-dependent activity, with strong inhibition against S. aureus comparable to tetracycline at 200 µg/mL, and moderate efficacy against E. coli. These findings highlight the dual therapeutic potential of A. senegalensis stem-bark extract as both a hepatoprotective and antibacterial agent. Future studies are recommended to isolate and characterize the bioactive compounds responsible for these effects and to expand antibacterial evaluation to a wider spectrum of pathogens.
Co-Authors A, Ajala-Lawal R. A, Arowora K. A., Arowora K. Abah, Moses Adondua Abbas, Khalid Yahuza Abbas, Sabahat Abdulghafoor, Hind A. Abdulkadir, Nurudeen Umar Abdulrasheed, Lubabatu Abershi, Ajiduku Leyoa Absalom, Augustine Abu, Michael S. Abu, Michael Sunday Acha, Ozzioma Praise Adam, Habiba Idris Adam, Idris Habiba Adams, Idris Habiba Adamu, Usman Lukman Adebisi, Arowora Kayode Adeseye, Abdullahi Sa’adu Adi, Godwin Baaku Agaba, Eric Agim Agwu, James Eneji Ahmed, Fasihuddin Badruddin Ahmed, Maryam Usman Ahmed, Misbah Aisami, Abubakar Akafa, Andes Tensaba Akafa, Tensaba Andes Akafa, Vika Tensaba Akam, Odok Endurance Akem, Ingwu Joseph Akem3, Ingwu Joseph Al-Musawi, Jehan Mohammad Al-Musawi, Jehan Mohammed Ale, Ebenezer Morayo Ali, , Jaouher Ben Ali, Jaouher Ben Aliyu, Sulaiman Abubakar Alooma, Emmanuel Amen, Ananias Ametefe, Mathias Mawuli Amofa, Gift Amuda, A. J. Andeuka, Useni Ajiya Asare, Solomon O. Asare, Solomon Ossom Aslam, Muhammad Tayyab Aslam, Nosheen Asuelimen, Steve Osagie Audu, Anthony Mishara Audu, Jankada Patience Ayara, Charles Ayi, Atsu Ayo, Victoria Ifeoluwa Bafai, Favour Joel Baig, Muhammad Haris Bando, David Christopher Bappa, Lipana Dorcas Benjamin, Wisdom L. Bobie, Shelter Agbeko Brown, Samuel Tamunoiyowuna Cockeye C, Ugwuoke Kenneth Chikata, Ezugwu Hilary Chinedu, Imo Chinonso, Anih David Chishti, Abdul Wadood Chisom, Gabriel Favour Chuanu, Solomon Chukwudi, Emmanuel Eluu Dambazau, Zainab Bello Daniel, Benjamin Nanisi Danjuma, Janya Danjuma, Tyem Lawal Dauda, Mai-anguwa Abdulrashid Dauda, Maianguwa Abdulrashid Dauda, Maianguwa Abdulrsashid David, Bando Christopher David, Izam Emmanuel Dooshima, Arowora Mercy Efongwa, Emmanuel Efoseh, Danlami Ejeh, Yakubu Ojochenemi Ekpo, Fidelis Okii Ekubnse, Nkiri Annasthesia Ekunyi, Agbo Chibuike Ekup, Ogholo Ogholo Emmanuel, Okoli Emochone, Roy Yohanna Enang, Kingsley Bassey Enyojo, Lawal Favour Esseyi, Chabunda Endashi Essien, Inemesit Samuel Ezeonu, Chukuma Stephen Frank, Otashu Kenneth Galam, Nanyak Zingfa Gbadebo, Adetoyi Moses Ghazwani, Eisa Yazeed Goje, Lazaru Joseph Grace, Onwubiko N. Gyasi, Prince Kwadwo Habibu, Bilyaminu Hasan, Mohammed Khudhair Hassan, Okrah George Henry, Onwubiko A. Iftikhar, Momina Iheanacho, Chinedu Christian Ijeomah, Nkechi Gift Ikira, Usman Innocent, Nwofor Ipav, Selumun Solomon Iseko, Kingsley Iyoko Ismail, Muhammad Zuhairah Istifanus, Dafup Kadel Istifanus, Dafup Katdel Jabir, Abdulmumin Jack, Precious Chioma Jacob, Mathew Janya, Danjuma Javed, Amna Jehan Mohammed Al-Musawi, Jehan Mohammed Joel, Emmanuel Askeb-nde Joel, Emmanuel Askebnde John, Artu Ishishen John, Omachi Blessing John, Tongle Nanle Johnson, Joanna Afariba Joseph, Ikwebe Joseph, Iornenge Terungwa Kayode, Arowora Khan, Alam Afroz Urooj Khan, Fahad Said Kingsly, Iseko Iyoko Konka, Daniel Laila, Umme Madaki, Kanati Mafe, Alice Njolke Mahmood, Abid Maianguwa, dulrashid Dauda Makanjuola, Victor Malantso, Jackson Soyinka Maqbool, Tahmina Marvelous, Solomon Godiya Matilda, Manasseh Ilumunter Mchibuma, Jibaniya Grace Melvin, Ugwuala Chimaobi Mijinyawa, Aboki Nwunuji Mijinyawa, Ibrahim Jamilat Mohammed, Ikrimah Usman Mohammed, Rashida Ismail Mona, Etah Hope Morayo, Ale Ebenezer Morgan, Akpan Usenobong Morolake, Olabanji Martina Moses, Iyekekpolor Osamudiame Muhammad Abdullah Muhammad Akram Muhammad, Muhammad Bashir Mustapha, Musa Azegya Najeeb, Aliyu Olamilekan Namuma, Shitta Nasisi Nanmar, Chakfa Ngabea, Nasiru Audu Ngbede, Ocheifa Mathew Ngbede, Ocheifa Matthew O, Mosugu O. Odufa, Egbeadumah Maryanne Ogochukwu, Edom Favour Okang, Ogar Fonne Oko, John Odiba Okoli, Emmanuel Chikodiri Okwori, Ameh Godwin Oladele, Gloria Omonefe Oladimeji, Oluwasegun M. Olawale, Otitoju Olawale, Otitujo Olayemi, Abimbola Gbenga Olayeni, Abimbola Gbenga Oluwabunmi, Adeseye Helen Oluwabunmi, Helen Oluwale, Otitoju Omanchi, Emmanuel Omolara, Mosugu Ovayoza Onyindia, Agbo Christiana Onyinyechi, Nwachukwu Favour Oteng, Joseph Otitoju, Olawale Oyibo, Okpanachi Nuhu Ozdemi, Fethi Ahmet Ozdemir, Fethi Ahmet Peter, Danladi Mbosire Peter, Prosper Uneju Philemon, Panah Philip, Shadrach Rashid, Abid Rebecca, Tsokwa Punarimam Rehman, Urooj S, Ezeonu C. Sadia, Haleema Salman, Julius Ishaya Shadrach, Katchim Evelyn Shadrach, Philip Shahid, Isbah Shaibu, Isaac Eleojo Sheneni, Victor Duniya Shenia, Zephaniah Hananiah Siddan, Ahmad Alhassan Sirina, Bakari Genevieve Sołowski, Gaweł Sule, Josephine Maina Sunday, Abu Michael Sunday, James Agbu Talent, Akoh Miracle Tansaba, Akafa Andes Tensaba, Akafa Andes Tiimob, Gideon Likida Timothy, Mgbede Tyem, Lawal Danjuma Uchechukwu, Ukoh Daniel Udoh, Mary Athanasius Uduak, Peter Ise Ugbedeojo, Sule John Ugoeze, Egeonu Stephen Ujah, Oche Williams Ujah, Williams Oche Umahi, David Umar, Kerenhappuch Isaac Umaru, Hauwa A. Umaru, Kerenhappuch Isaac Umaru, Kerenhapucch Isaac Umogbai, Debora Akinola Utioukpan, Ashaka Fidelis Williams, Queen Uyo Wilson, Ubur Terzulum Yahaya, Musbau Adekunle Yakubu, Kaka Garpiya Yakubu, Ojochenemi E. Yakubu, Ojochenemi Ejeh Yeboah, Genevieve A. Yeboah, Genevieve Akpah Yemisi, Adeyanju Kate Yuguda, Ismail Yunusa Yusuf, Obadiah Saveni Yusufu, Dawoye Zinas, Simon Teza