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Kadar radikal superoksid (O2-), nitric oxide (NO) dan asupan lemak pada pasien hipertensi dan tidak hipertensi Astutik, Pudji; Adriani, Merryana; Wirjatmadi, Bambang
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 1 (2014)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (452.1 KB) | DOI: 10.14710/jgi.3.1.90-95

Abstract

Background: Hypertension closely related to impaired endothelial dependent vasodilation due to a decline in theavailability of nitric oksid (NO) and high fat intake, decreased Nitric Oksid caused due to increased levels ofsuperoksid.Objective: to analyze the differences in the levels of Superoksid Radical (O2-), Nitric oxide (N0) and fat intake inpatients with hypertension and not hypertension .Methods: this research is cross sectional, research amount sampelnya taken at random. 24 respondent patientsconsisting of 12 cases control, and 12 the age of 65 40- tahun.pengambilan samples conducted in outpatient installationregional general hospital Sidoarjo. Done bseline superoksid levels, nitric oxide and recall fat intake.Results: the average rate of Superoksid respondents not hypertension 0.250± 0, 034U/mL, 0,314± 056U/mLhypertension, Average levels of Nitric oksid respondents not hypertension 116,083± 46,962μ M, of which hypertension72,333± 40,51μ M, average consumption of fat respondents not hypertension 41,65± 8, 32gram, 51,52± 6,74gramhypertension . Based on the test results the difference against Superoksid levels of both research groups using a t-testtwo samples are free retrieved the value p < 0,05 (p = 0,004), NO content retrieved the value p < 0,05 (p = 0,023), fatintake obtained the value of p < 0,05 (p = 0,004) which means that there is a meaningful difference in the levels ofSuperoksid, Nitric oxide and the level of fat intake among respondents with no hypertension and hypertension.Conclusion: there is a radical difference in the levels of Superoksid, NO (Nitric Oxide) and fat intake in patients withhypertension and not hypertension.
Antibacterial Activity of Extract Ethanol Bidara Leaves (Ziziphus spina-Christi L) on Enteropathogenic coli Sri Mulyani1 , Merryana Adriani 2, Bambang Wirjatmadi2
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13638

Abstract

Prokaryotic bacteria are microorganisms can beneficial as normal flora, but also can have health due todisease pathogens and is for the host. The purpose of this study is to find compounds in extract ethanolbidara leaves those compounds and activities against bacteria Enteropathogenic coli. This study shows theflavonoid compounds and tannin in extract ethanol bidara leaves (Ziziphus spina-Christi L) to minimuminhibitory zone at concentrations 50% and minimum bactericidal at concentrations 75%. The higherconcentration extract ethanol Bidara leaves the larger the drag zone produced. The research is experimentalstudy looking the extract ethanol antibacterial activity Bidara leaves with the methods in vitro test diffusion.This study found a chemical compound which is found in extract ethanol Bidara leaves (Ziziphus spinaChristi L) is flavonoid and tannin have antibacterial activity106 CFU/ml against bacteria Enteropathogeniccoli to minimum inhibitory zone at concentrations 50% and minimum bactericidal at concentrations 75%.
Nurses’ Spirituality Improves Caring Behavior Abu Bakar; Nursalam Nursalam; Merryana Adriani; Kusnanto Kusnanto; Siti Nur Qomariah; Laily Hidayati; Ika Nur Pratiwi; Lailatun Ni&#039;mah
International Journal of Evaluation and Research in Education (IJERE) Vol 6, No 1: March 2017
Publisher : Institute of Advanced Engineering and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (426.332 KB) | DOI: 10.11591/ijere.v6i1.6343

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Caring was the behavior provide assistance holistically to individuals. In fact, nurses Caring behaviors made only modest, yet an art in nursing care which should always be a nurse. The good personality and spiritual be one of the factors that affect the formation of nurses Caring behaviors. Spiritual was the passion or impulse that comes out from within themselves to do the noble. The research objective was explained a spiritual relationship nurses with nurses caring behaviors. The research design was used cross sectional. The population in this researchs were associate nurses in the ward. A sample were taken of 88 nurses with consecutive sampling technique. Data collection was done at the General Hospital of Haji Surabaya, Al Irsyad General Hospital Surabaya and Muhammadiyah Gresik Hospital. Data collection was used questionnaire, with multivariate data analysis Structural Equation Modeling- Partial Least Square (PLS-SEM). The results showed no significant relationship between demographic with spiritual nurses. Demographic indicators for the hypothesis test was psychological, length of work, education, and wards. Demographics nurses with nurse caring no significant relationship. Spiritual nurses significant relationship with the caring nurses at 7.061. These results indicated that modeling should be done was draw line from the spiritual to the caring nurses and the others deleted. The conclusion of the research was the spiritual nurses significant relationship with the nurses caring behaviors. Suggestions have to do is always give spiritual training to nurses as one of supporting the implementation of nursing care.
The Effect of Black Cumin (Nigella sativa) Oil Supplementation on Hematotoxicity Induced by Benzene in Gasoline Vapors from Gas Stations in Male Wistar Rats Ikhram Hardi S; Merryana Adriani; Tri Martiana
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15810

Abstract

This study aimed to prove the effect of black cumin oil supplementation through analysis of levels of CYP2E1, MDA, GSH, and hematological profiles in experimental animals, Wistar rats, which were exposed to benzene in gasoline vapors from gas stations. Sixty-four experimental Wistar rats were divided into eight groups with eight rats each, two control groups (C1 and C2), and six experimental groups (T1, T2, T3, T4, T5, and T6). Blood samples of experimental rats were taken through intracardiac with ketamine-xylazineacepromazine anesthesia on day 15 for group C1, C2, T1, T3, and T5; and day 29 for group T2, T4, and T6. The ELISA method measured the levels of CYP2E1, GSH, and MDA in this study, while the hematological profile used a hematology analyzer. This study indicates that benzene in gasoline vapors exposure caused significant hematotoxicity (P <0.05). Supplementation of black cumin seed oil at a dose of 2.5 ml/kg, 5 ml/kg, and 10 ml/kg, all of which have the potential to provide a protective effect against the hematotoxicity of benzene in gasoline vapors through increased internal antioxidants (GSH). The GSH can play a role in the mechanism of vapor metabolism of substances in gasoline vapors in the body through decreased CYP2E1 levels and decreased MDA levels. Further research is still needed with a more extended treatment duration to ascertain the chronic effects of benzene hematotoxicity on the genomic pathway to assess black cumin’s role, whether in the form of oil, powder, or other forms of extraction.
Analysis of the Effect of Potassium of Young Coconut Water Consumed by Pregnant Women in the Third Trimester on the Levels of Potassium Saliva of Mothers and the Newborn as well as Meconium Levels of Amniotic Fluid as an Indicator of Meconium Staining Tri Ratna Ariestini; Merryana Adriani; Windhu Purnomo; Shrimarti Rukmini Devy
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16018

Abstract

Background: Meconium staining of amniotic fluid harms newborns. Pregnant women in Palangka Raya City have the habit of consuming young coconut water to prevent the meconium staining of amniotic fluid. Young coconut water contains the highest mineral potassium. Potassium can affect the intestinal peristaltic.Objective: Analyzing the effect of potassium of young coconut water consumed by pregnant women in the third trimester on the levels of potassium saliva of mothers and the newborn and meconium levels of amniotic fluid.Methods: This study was a prospective cohort study of third-trimester pregnant women. The study sample was taken randomly, 24 pregnant women who consumed young coconut water and 24 who did not consume young coconut water.Results: Potassium levels of young coconut water had a positive correlation with levels of maternal salivary potassium (b = 0,414, p = 0,000). Maternal salivary potassium levels had a negative correlation with meconium levels of amniotic fluid (b = -0,603, p = 0,000). Maternal salivary potassium levels through infant salivary potassium levels had a negative correlation with meconium levels of amniotic fluid (b= -0,205, p = 0,000).Conclusion: Young coconut water consumed by pregnant women during the third trimester can prevent the meconium staining of amniotic fluid
Pengaruh Terapi Kognitif Spiritual Terhadap Penurunan Depresi pada Lansia di panti Werdha Ratna Sari Rumakey; Merryana Adriani; Retno Indarwati
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 11, No 1 (2020): Januari 2020
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf11122

Abstract

Depression in the elderly can cause dysfunction in daily life. This study aims to analyze the impact of spiritual cognitive therapy on decreasing depression in the elderly in nursing homes. This type of research was quasy experimental, with 61 elderly subjects with depression. The statistical test used was the Wilcoxon Signed Ranks Test. The results showed that spiritual cognitive therapy influenced the reduction in depression, marked p-value = 0,000. Keywords: spiritual cognitive therapy; depression; elderly ABSTRAK Depresi pada lanjut usia dapat menyebabkan gangguan fungsi dalam kehidupan sehari-hari. Penelitian ini bertujuan untuk menganalisis dampak terapi kognitif spiritual terhadap penurunan depresi pada lansia di panti werdha. Jenis penelitian ini adalah quasy experimental, dengan subyek yaitu 61 lansia dengan depresi. Uji statistik yang digunakan adalah Wilcoxon Signed Ranks Test. Hasil penelitian menunjukkan bahwa terapi kognitif spiritual berpengaruh terhadap penurunan depresi, ditandai p-value = 0,000. Kata kunci: terapi kognitif spiritual; depresi; lansia
The Role of Addition of Vitamin C in Iron Supplementation on Ferritin Serum Levels in Anemia Adolescent Females Nanik Dwi Astuti; Bambang Wirjatmadi; Merryana Adriani
Health Notions Vol 2, No 3 (2018): March
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (273.691 KB) | DOI: 10.33846/hn.v2i3.147

Abstract

Prevention of iron deficiency anemia in Indonesia using ferrous sulfas blood-added tablets started since 1997. But iron deficiency anemia is still high, also in young women. Young women are vulnerable because of rapid growth and unhealthy their consumption patterns, which rarely consume fruits and vegetables that are a source of vitamin C. The purpose of this study was to analyze the addition of vitamin C in iron supplementation + folic acid to serum ferritin levels in adolescents females anemia. This research was an experimental quasi research. Design of research was Randomized Pre Post Test Control Group Design, with Double Blind treatment. This study had one treatment group and one control group, each group of 11 samples. The samples were chosen randomly with inclusion and exclusion. The collected data was processed using SPSS program with the analysis of paired t-test and independent t-test to test the difference of serum ferritin level. The results was showed the characteristics of respondents: age (p = 0.430), education of mother (p = 0.942) and nutritional knowledge of respondents (p = 0.928) in the same condition or both groups were had homogeneous characteristics. The pattern and level of food consumption were showed no different between control and traetment groups (p> 0.05). Serum ferritin levels showed difference between the two groups after treatment (p = 0.004). The study was showed vitamin C had role in increasing iron absorption and fill in storage of ferritin formation. Keywords: Anemia, Vitamin C, Iron supplement, Ferritin
Green Tea (EGCG) Decreases Malondialdehide in Oxidative Stress Exposure to Psychological Stress M. Dodi F Priaminda; Bambang Wirjatmadi; Bambang Purwanto; Merryana Adriani
Health Notions Vol 2, No 7 (2018): July
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn20707

Abstract

Exposure to psychological stress can cause oxidative stress. Provision of exogenous antioxidants is expected to reduce the occurrence of oxidative stress. Green tea with its active ingredient Epigalocatechin Galat is considered to reduce the occurrence of oxidative stress. The purpose of this study was to examine the administration of green tea (EGCG) on the effect decreasing MDA levels against Wistar Strain (Rattus norvegicus) white rats exposed to psychological stress; with Randomized Post Test design of only group design by grouping into 5 groups, with control group and treatment group. Administration of steeping green tea (EGCG) with a single dose. To find out the significant influence of the independent variable on a set of variable group tested Manova. Post hoc testing using LSD (Least Significance Different) was performed to see significant differences between groups. In this study, obtained MDA data with significant decrease at the 6th hours after consum EGCG. Keywords: oxidative stress; green tea, EGCG, malondialdehide
Robusta Coffee Decreased Malondialdehyde Levels in Wistar Mice Experiencing Oxidative Stress Rahmi Syarifatun Abidah; Bambang Wirjatmadi; Bambang Purwanto; Merryana Adriani
Health Notions Vol 1, No 4 (2017): October-December
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (607.78 KB) | DOI: 10.33846/hn.v1i4.68

Abstract

Coffee drinking is a habit that still doubtful for it’s benefits. Many active ingredients in robusta coffee (Coffea canephora) are very useful for health, especially the antioxidant content that can ward off free radicals that absorbed in the body. Free radicals can be caused by psychological stress exposure. Excessive amounts of radicals in the body cause oxidative stress. This study aimed to see the robusta coffee effect on decreasing levels of Malondialdehyde (MDA) with “randomized post test only control group” design with 25 samples of white male rat strain wistar (Rattus norvegicus). Samples were divided into 5 groups: control groups and randomized treatment groups. Treatment given in psychological stress and giving robusta coffee drink with single dose. This study used “one way anova” test and followed by “pos hoc tukey HSD” test for statistics. Robusta coffee had an effect in MDA levels changing. There was a MDA levels decreasing in 1 hour after robusta coffee drinking in experimental rats with oxidative stress conditions that were exposed by psychological stress. Keywords: Robusta coffee, Malondialdehyde, Oxidative stress
Young khalaal dates (Phoenix dactylifera) effect on blood glucose in alloxan-induced wistar male rats Desty Muzarofatus Sholikhah; Bambang Wirjatmadi; Merryana Adriani
Health Notions Vol 2, No 1 (2018): January
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (467.658 KB) | DOI: 10.33846/hn.v2i1.102

Abstract

This study analyzed young dates (Phoenix dactylifera) effect on blood glucose in alloxan-induced male wistar rats. It used a completely randomized design with pre-post test and control group design. The research samples were 25 male white wistar rats that divided into 5 groups: (1) negative control group with no treatment (K1); positive control group with alloxan induction only (K2); treatment group 1 with alloxan induction and 0.25 g/day of young dates treatment (P1); treatment group 2 with alloxan induction and 0.5 g/day of young dates treatment (P2); and treatment group 3 with alloxan induction and 1 g/day of young dates treatment (P3). The result were tested by Kolmogorov-Smirnov normality test (p>0.05), Levene's homogeneity test (p>0.05), followed by General Multivariate Manova test by Wilks' Lambda, between-subject effect test, and LSD (p<0.05). The results indicated that young dates could effectively reduced the blood glucose levels (p = 0.000). The fasting blood glucose level in positive control group (K2) was different from negative control group (K1, p = 0.000) and all treatment groups (P1, p = 0.000, P2, p = 0.000 and P3, p = 0.000). 0.25 g/day of young dates treatment could effectively reduced the fasting blood glucose level in alloxan-induced male wistar rats. Keywords: young dates, blood glucose levels, alloxan
Co-Authors Abdillah, Bagus Ahmad Nur Abu Bakar Achmad Ali Basri Ade Saputra Nasution Aditia Rida Purnamasari Agus Sulistyono Ajeng Putri Rahmandita Amanda Nurqisthy Anindya Mar’atus Sholikhah Anisatun Azizah Annis Catur Adi Annisa Rachma Firdausi Darmawan Aprilia Nurcahyaning Rahayu Arinda Lironika Suryana Arwati, Niluh Arwati, Niluh Arya Ulilalbab Astuti, Nanik Dwi Aulia, Kharina B Wirjatmadi Bambang Purwanto Bambang Purwanto Bambang Purwanto Bambang Wiratmadi Bambang Wirjadmadi Bambang Wirjatmadi BAMBANG WIRJATMADI Bambang Wirjatmadi Bambang Wirjatmadi Bambang Wirjatmadi Bambang Wirjatmadi Bambang Wirjatmadi Bambang Wirjatmadi Brigita Rainy Oktiva Candra Panji Asmoro, Candra Panji Cici Damayanti D.A. Liona Dewi Denna Rahinda Yulia Fanni Desy Prasetya Desy Prasetya, Desy Dewi Retno Suminar Dini Ririn Andrias Dini Setiarsih Dwi Putra, Kartika Wahyu Dwi Winarni Elida Ulfiana Fajar Afrindo Fara Disa Durry Farapti Farapti Fatifa Asmarani Fatifa Asmarani, Fatifa Fika Mayrlina Anggrayni Haryana, Nila Reswari Hermadani, Candraningtyas Ika Nur Pratiwi Ikhram Hardi S Indarwati , Retno Intan Galih Cornia Jayanthi Petronela Janggu Jayanthi Petronela Janggu Jujuk Proboningsih, Jujuk Junaida Astina Kartika Wahyu Dwi Putra Kharina Aulia Kuntoro Kuntoro Kuntoro Kuntoro Kusnanto Kusnanto Kusnanto Kusnanto Laila Nurayati Lailatul Muniroh Lailatun Ni&#039;mah Laily Hidayati Lestari, Annisa Arifiana Lury Novita Yustianingrum M. Dodi F Priaminda M., Soenarnatalina Mahmud Aditya Rifqi Maria Widijanti Sugeng Meirna Dewita Sari Muhammad Dimas Bimantara Mustika Putri Kustiyoasih Nanik Dwi Astuti Nathania Helsa F. Losong Ni Putu Wahyuningsih Nina Agustina Novera Herdiani, Novera Nur Nashriana Jufri Nursalam Nursalam Nursalam, Nursalam Oktovina Rizky Oktovina Rizky, Oktovina Pei-Lun Hsieh Priaminda, M Dodi F Pudji Astutik Pudji Astutik, Pudji Puspita Ayu Ramadhani Rachmah, Qonita Rachmat Hargono Raharja, Kristian Triatmaja Rahayu, Aprilia Nurcahyaning Rahmi Syarifatun Abidah Rahmi Syarifatun Abidah, Rahmi Syarifatun Ratna Sari Rumakey Reineldis Trisnawati Rifka Laily Mafaza Rina Wasesa Aprilia Lazulfa Rista Fauziningtyas, Rista Rivan Virlando Suryadinata Rivan Virlando Suryadinata Rivan Virlando Suryadinata Rizka Amalia Habiba Rosita Andriani Santi Kusumastuti Setho Hadisuyatmana Setiarsih, Dini Sheila Monica Kelly Amalia Sheryll Deby Regyna Sholikhah, Anindya Maratus` Sholikhah, Desty Muzarofatus Shrimarti Rukmini Devy Silviana Putri Siti Nur Qomariah Siti Rahayu Nadhiroh Soenarnatalina M. Soenarnatalina Meilanani Soenarnatalina Meilanani, Soenarnatalina Sri Hartiningsih Sri Hartiningsih Sri Hartiningsih Stefani Cornelia Sardjono Susanti, Yuyun Erlina Susanti, Yuyun Erlina Susila Rusdiana Dewi Tia Eka Novianti Tri Martiana Tri Ratna Ariestini Triharini, Mira Triska Susila Nindya Wijatmadi, Bambang Windhu Purnomo Wiratmadi, Bambang Yayuk Estuningsih Yeni Susanti