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All Journal International Journal of Public Health Science (IJPHS) Farmasains : Jurnal Farmasi dan Ilmu Kesehatan BALI MEDICAL JOURNAL (BMJ) Media Penelitian dan Pengembangan Kesehatan Jurnal Tumbuhan Obat Indonesia Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education Majalah Obat Tradisional JURNAL PENGABDIAN KEPADA MASYARAKAT UNEJ e-Proceeding Journal of Islamic Pharmacy The Indonesian Biomedical Journal Jurnal Farmasi Sains dan Komunitas Journal Of Vocational Health Studies FITOFARMAKA: Jurnal Ilmiah Farmasi PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Madaniya Humanism : Jurnal Pengabdian Masyarakat Farmasis: Jurnal Sains Farmasi Pharmaceutical Sciences and Research (PSR) Borneo Journal of Pharmacy Journal of Tropical Pharmacy and Chemistry Jurnal Sains dan Kesehatan
Mangestuti Agil
Faculty Of Pharmacy, Universitas Airlangga
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Public Health Social Sciences

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Journal : Majalah Obat Tradisional

 1 
ANALISIS FITOKIMIA EKSTRAK N-HEKSANA DAN FRAKSI DAUN Marsilea crenata Presl. DENGAN GC-MS Burhan Ma'arif; Mangestuti Agil; Hening Laswati
Majalah Obat Tradisional Vol 21, No 2 (2016)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (989.301 KB) | DOI: 10.22146/tradmedj.12821

Abstract

Estrogen deficiency causes various health problems in postmenopausal women, including osteoporosis. Phytoestrogen emerged as a potential alternative of estrogen with minimum side effects. Green clover (Marsilea crenata Presl.) is a typical plant in East Java which suspected contains estrogen-like substances. The aim of this research was to report the phytochemical properties of M. crenata using GC-MS as a preliminary study. M. crenata leaves were dried and extracted with n-hexane, then separated using vacuum column chromatography to get four fractions, after that the n-hexane extract and four fractions were identified with GC-MS. The results of GC-MS analysis showed some compounds contained in M. crenata leaves like monoterpenoid, diterpenoid, fatty acid compounds, and other unknown compounds. The results obtained in this research indicated a promising potential of M. crenata as medicinal plants, especially as antiosteoporotic agent.
AKTIVITAS ANTIOSTEOPOROSIS EKSTRAK ETANOL 96 % DAUN Abelmoschus manihot L. MEDIK SECARA IN VITRO MENGGUNAKAN SEL PREOSTEOBLAS MC3T3-E1 Agnis Pondinekaria Aditama; Mangestuti Agil; Hening Laswati
Majalah Obat Tradisional Vol 21, No 3 (2016)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (571.975 KB) | DOI: 10.22146/tradmedj.17297

Abstract

Osteoporosis is a disease characterized by low bone mass and structural deterioration of bone tissue. Estrogen deficiency causes loss of bone mineral density which causes osteoporosis. Phytoestrogen is a potential alternative of estrogen that can be used as Hormone Replacement Therapy on osteoporosis with minimum side effects. Many edible plants contain phytoestrogens that are believed to promote bone health. Abelmoschus manihot (L.) Medik has been known as a plant that is empirically used in the traditional medicine and has potency to prevent osteoporosis. The aim of this research is to determine whether the Abelmoschus manihot (L.) Medik leaves have the potential to increase bone formation in an in vitro assays using preosteoblast cell line MC3T3-E1. The results showed an increasing activity of Alkaline phosphatase using confocal laser scanning microscopy technique.
Co-Authors Abdul Hafid B Agnis Pondineka Ria Aditama Ahmaniyah Almay Abidzar Elpasha Amalia, Dilla Anisah Mahardiani Anita Joeliantina Arief Suryadinata Arijanto Jonosewojo Artabah Atik Kurniawati Bambang Wirjatmadi Begum Fauziyah Besin, Valentinus Burhan Ma'arif Burhan Ma'arif Burhan Ma'arif Burhan Ma'arif Burhan Ma'arif Burhan Ma'arif Burhan Ma’arif Burhan Ma’arif Burhan Ma’arif Burhan Ma’arif Burhan Ma’arif Damaranie Dipahayu Damaranie Dipahayu Damaranie Dipahayu Damaranie Dipahayu, Damaranie Denis Denis Mery Mirza Destiya Argo Pamuji Fihuda Dewi Isadiartuti Dilla Amalia Djoko Agus Purwanto Edith Frederika Puruhito, Edith Frederika Eko Pujiono, Feri Elkania Putri, Safira Esti Hendradi Fadlilah, Nazilatul Faisal Akhmal Muslikh Fatah, Mohammad Zainal Fathia Faza Rahmadanita Fihuda, Destiya A. P. Fihuda, Destiya Argo Pamuji Firdausy, Alif Firman Guhir, Abdul Malik Hajar Sugihantoro Heni Pujiastuti Hening Laswati Hening Laswati Putra Herra Studiawan Husnul Khotimah Imam Subadi, Imam J. A. Pangkahila Jatmiko, Ricky Arie Juni Ekowati Jusak Nugraha Kusnanto Kusnanto Luthfi Achmad Muchlasi M. Artabah Muchlisin M. Bagus Qomaruddin M. Bagus Qomaruddin Ma'arif, Burhan Marta Ika Riyana Maximus M Taek Meilina Ratna Dianti Melanny Ika Sulistyowaty Merryana Adriyani Mohammad Hasan Machfoed Muslikh, Faisal A. Muslim, Menara Nabila Rosa Naesilla Naesilla Ni Made Mertaniasih Ninis Yuliati, Ninis Notopuro, Paulus Budiono Novia Maulina Nyimas Yusma Aemi Oedojo Soedirham Poernomo, A.Toto Pramudita Riwanti Purbosari, Ira Purwitasari, Neny Qurnianingsih, Ema Rahmi Annisa Rakhmawati Rakhmawati Resti Perslami, Resti Retno Widyowati Reyhan Rahma Samudra Ria Ramadhani Dwi Atmaja Riyanti, Anisa Eka S.Pd. M Kes I Ketut Sudiana . Sadli Syarifuddin Saidah, Nisfatul L. Saidah, Nisfatul Lailatus Sari, Dewi Perwito Setyo Wiyono, Anang Shrimarti Rukmini Devy Siswandono Siti Maimunah Suko Hardjono Supriyadi Supriyadi Suwarno Putra, Adryansyah Taek, Maximus M. Tanaya Jati Dharma Dewi Tri Widiandani Tutik Sri Wahyuni Widji Soeratri Wirda Anggraini Yunita Satya Pratiwi Yusniasari, Putri Antika Zulvikar Syambani Ulhaq