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All Journal Jurnal Kesehatan Andalas Berkala Ilmu Kesehatan Kulit dan Kelamin Biomedical Journal of Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Review Pendidikan dan Pengajaran (JRPP) Health and Medical Journal JURNAL PENELITIAN PERAWAT PROFESIONAL Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks JOURNAL LA MEDIHEALTICO Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Indonesia Sosial Sains Detector: Jurnal Inovasi Riset Ilmu Kesehatan Prosiding Seminar Nasional Unimus Seroja Husada: Jurnal Kesehatan Masyarakat Proceeding International Conference Of Innovation Science, Technology, Education, Children And Health Proceeding International Conference Of Innovation Science, Technology, Education, Children And Health
Gardenia Akhyar
Andalas University
Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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A Challenge In Establishing The Etiologic Of Toxic Epidermal Necrolysis In Children Jefrizal Wirman; Gardenia Akhyar; Irdawaty Izrul; Qaira Anum
Proceeding International Conference Of Innovation Science, Technology, Education, Children And Health Vol. 2 No. 1 (2022): Proceeding of The International Conference of Inovation, Science, Technology, E
Publisher : Program Studi DIII Rekam Medis dan Informasi Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/icistech.v2i1.33

Abstract

Background: Toxic epidermal necrolysis (TEN) is a rare especially in children, acute and potentially lifethreatening. The etiology of the higher incidence of TEN in various pediatric age groups than in adults is unclear, the cause is multifactorial. TEN have known triggering events, including infections (commonly viral or mycoplasma) drugs/herbs, malignancy, vaccines, and idiopathic. Case report: We reported a case TEN of a 5 years old boy. There was a history of fever and red rash on the patient's hands 5 days ago and taken paracetamol, amoxicilin, chlorpeniramin maleat(CTM), and vitamin C, then a red patch and blisters appears 12 hours later. Physical examination: composmentis, temperature 38,80C. Dermatological state: erythemathous macules, vesicles, bulla, erosions, excoriations, crusts on the most of body. Hyperemic conjunctiva, on oral mucosa there were erythematous oedem, erosion, excoriation and reddish-blackish crust, and erosion of the genitalia. Epidermolysis was about ± 40%. Laboratory examination :leucocyte 5300/mm3 with lymphocytosis. Serum urea increases, serum bicarbonate decreases. The patient was treated dexamethasone intra venous and decreased dose with prednisone oral, patient improved and healed on day 13. Discussion: The diagnosis of TEN in patients is made based on history and physical examination. We can establish a typical diagnosis of TEN from clinical symptoms and physical examination, but to find the etiology is sometimes difficult and requires a deep history and other investigations. The etiology in this case cannot be established because of drugs or infection. To find out, it is necessary to do further tests such as serology or PCR
Co-Authors Abdiana Abdiana, Abdiana Adissa Benanda Afdal Afdal, Afdal Afdhila , Irhamni Nur Afriani, Nita Agustin Vira Agustin Vira Alimuddin Tofrizal Alvarino Alvarino Amelin, Fitrisia Andani Eka Putra Andrini Ariesti Andrini Ariesti Anum, Qaira Ashal, Taufik Asri, Ennesta Astria Rima Rara Yuswir Astria Rima Rara Yuswir Benanda, Adissa Cimi Ilmiawati, Cimi Dedy Kurnia Endrinaldi Ennesta Asri Ennesta Asri Erlina Rustam Fathiyyatul Khaira, Fathiyyatul Fauzana Nazifah Fikri Fadhil Fortuna, Fory Gusti Revilla Hendriati, Hendriati Husna, Annisa Tamara I. Izrul Ida Rahmah Burhan Indah Indria Sari Indah Indria Sari Irdawati Izrul Irdawaty Izrul Irhamni Nur Afdhila Izrul, Irdawaty Jefrizal Wirman Julita Julita Julita Julita Julizar Julizar Kemala Sayuti Kurnia, Dedy Lestari, Rahmi M. Ashar Maimi, Afaf Aqil Mardhiati Mardhiati Meligasari L Gaya Mutia Sari Nagara, Adianto Jaya Nailatul Fadhila Netti Suharti, Netti Novian Novian Novian Novian Nur, Fauziah Nurul Izzah Rahma Ledika Veroci Raveinal Rendra Darma Satria Rendra Darma Satria Rika Desviorita Rika Desviorita Rina Gustia Rina Gustia Riri Prima Yolanda Rizki Dwayana Rizki Dwayana Rizkia Chairani Asri Salwa Azzahra Satya Wydya Yenny Syamel Muhammad Tiffany, Begum Tofrizal Tutty Ariani Tutty Ariani Vesri Yossy Vitresia, Havriza Yenni Raflis Yola Fadilla Yosse Rizal Yusticia Katar Zafira, Qory