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Journal : PROFESSIONAL HEALTH JOURNAL

Reducing blood uric acid levels after drinking Annona muricata linn (soursop leaf) extract: study in elderly with hyperuricemia Muhammad Al Amin; Ainun Najib; Ali Syahbana; Efina Amanda
PROFESSIONAL HEALTH JOURNAL Vol. 6 No. 1 (2024): December
Publisher : Pusat Penelitian dan Pengabdian Masyarakat (PPPM) STIKES Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54832/phj.v6i1.788

Abstract

Introduction: Gout is a degenerative disease that often attacks joints, especially in older adults. This disease is caused by the buildup of uric acid crystals in the joints, which causes inflammation and severe pain. One of the main indications that someone suffers from gout is if the results of measuring the uric acid level in the blood are more than 7.0 (mg/dL), whereas in women, it is more than 5.7 mg/dL. Objectives: Research to determine the effectiveness of A. Muricata leaf extract in reducing uric acid levels in older adults with hyperuricemia. Methods: Quantitative research, using a quasi-experimental type with Pre-test, Post-test design with control group design, with a sample size of 30 older adults, sampling technique using random sampling carried out for one week consuming one day three times. Results: The paired t-test showed a p-value of 0.0001, indicating a significant difference between the average uric acid levels before and after Annona muricata leaf extract administration. Soursop leaves contain flavonoid and tannin compounds, where flavonoids can inhibit the production of the enzyme xanthine oxidase. By inhibiting this enzyme, the process of forming hypoxanthine into xanthine is also hampered, thereby reducing excess uric acid production. Apart from reducing uric acid levels in the blood, soursop leaves can also reduce pain in people with gouty arthritis thanks to the tannin, resin and Agostini content, which can relieve pain and reduce swelling and pain. Conclusions: Administration of A. Muricata leaf extract has proven effective in reducing uric acid levels in older adults with hyperuricemia
Efektifitas Pembinaan Kader Kesehatan Remaja (KKR) tentang TRIAS UKS terhadap Upaya Pencegahan Kenakalan Remaja pada Siswa Tingkat SMA/MA Muhammad Al Amin; Achmad efendi; Pipit Hariyono; Akhmad Yanuar Fahmi Pamungkas
PROFESSIONAL HEALTH JOURNAL Vol. 1 No. 1 (2019)
Publisher : Pusat Penelitian dan Pengabdian Masyarakat (PPPM) STIKES Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54832/phj.v1i1.95

Abstract

UKS is an education and health effort that is carried out in an integrated, conscious, planned, directed, and responsible manner in instilling, growing, developing, and guiding to live, enjoy, and implement the principles of healthy life in the lives of everyday students (Ahmad Selvia, 2009: 1). Based on the problems and research objectives to be achieved, this type of research is preexperimental research in the form of a "one-group pre-post test" design. The target population in this study were all students and high school / MA students in the working area of Srono District, Banyuwangi Regency, amounting to 1,841 people. The sample in this study were some students and high school / MA students in the working area of Srono District, Banyuwangi District who met the inclusion criteria as many as 1,248 respondents. The sampling technique used in this study was Purposive sampling. From the results of the bivariate statistical test using the Wilcoxon Test analysis obtained p value <0.05 which is equal to 0,000. From the results of these calculations, it can be concluded that there is an influence between the formation of adolescent health cadres (KKR) on prevention efforts for juvenile delinquency in high school / MA / SMK level students in the Srono District work area in Banyuwangi Regency in 2016. Providing a good environment early on, along with an understanding of the development of our children well, will help reduce juvenile delinquency, so families, parents and the community are expected to be able to find a good strategy to protect their children from juvenile delinquency can damage their future.
Efektivitas Ekstrak Daun Annona Muricata Terhadap Penurunan Kolesterol Total Pada Lansia Dengan Hiperkolesterolemia Di Panti Werdha Mojopahit Mojokerto Muhammad Al Amin; Ainun Najib; Ali Syahbana
PROFESSIONAL HEALTH JOURNAL Vol. 5 No. 1 (2023): Desember
Publisher : Pusat Penelitian dan Pengabdian Masyarakat (PPPM) STIKES Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54832/phj.v5i1.405

Abstract

The elderly experience a decrease in function, especially in the function of blood circulation. Blood circulation diseases and hormonal metabolism disorders experienced by the elderly include hypercholesterolemia. Hypercholesterolemia is a disorder of fat metabolism that triggers an increase in total blood cholesterol levels, namely> 200 mg/dl. The study aimed to determine the effectiveness of A. muricata leaf extract in decreasing total cholesterol levels in the elderly with hypercholesterolemia. Quantitative research method, using a quasi-experimental type with a group pretest-posttest design, with a sample size of 20 elderly. The sampling technique used purposive sampling, was carried out for a week consuming three times a day. The paired t-test showed a value of 8.73 and a p-value of 0.001. This study's results indicated a significant difference between the average cholesterol levels in the pre-test and post-test administration of Annona Muricata leaf extract. Compounds contained in soursop leaves, namely flavonoids, by reducing the activity of HMG-koa reductase (enzyme β-Hydroxy β-methylglutaryl-CoA) can reduce the activity of ACAT (enzyme acyl-Coa cholesterol acyltransferase), and reduce the absorption activity of cholesterol in the liver. Digestive tract. Saponin compounds in soursop leave lower cholesterol by binding to cholesterol in the intestinal lumen, thereby preventing the reabsorption of cholesterol. Saponins can bind with bile acids, which in turn will reduce the enterohepatic circulation of bile acids and cause an increase in the process of excretion of cholesterol.
Reducing blood uric acid levels after drinking Annona muricata linn (soursop leaf) extract: study in elderly with hyperuricemia Muhammad Al Amin; Ainun Najib; Ali Syahbana; Efina Amanda
PROFESSIONAL HEALTH JOURNAL Vol. 6 No. 1 (2024): December
Publisher : Pusat Penelitian dan Pengabdian Masyarakat (PPPM) STIKES Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54832/phj.v6i1.788

Abstract

Introduction: Gout is a degenerative disease that often attacks joints, especially in older adults. This disease is caused by the buildup of uric acid crystals in the joints, which causes inflammation and severe pain. One of the main indications that someone suffers from gout is if the results of measuring the uric acid level in the blood are more than 7.0 (mg/dL), whereas in women, it is more than 5.7 mg/dL. Objectives: Research to determine the effectiveness of A. Muricata leaf extract in reducing uric acid levels in older adults with hyperuricemia. Methods: Quantitative research, using a quasi-experimental type with Pre-test, Post-test design with control group design, with a sample size of 30 older adults, sampling technique using random sampling carried out for one week consuming one day three times. Results: The paired t-test showed a p-value of 0.0001, indicating a significant difference between the average uric acid levels before and after Annona muricata leaf extract administration. Soursop leaves contain flavonoid and tannin compounds, where flavonoids can inhibit the production of the enzyme xanthine oxidase. By inhibiting this enzyme, the process of forming hypoxanthine into xanthine is also hampered, thereby reducing excess uric acid production. Apart from reducing uric acid levels in the blood, soursop leaves can also reduce pain in people with gouty arthritis thanks to the tannin, resin and Agostini content, which can relieve pain and reduce swelling and pain. Conclusions: Administration of A. Muricata leaf extract has proven effective in reducing uric acid levels in older adults with hyperuricemia
Co-Authors Achmad Efendi Aditya Wicaksono Afiati, Nila Ahmadi, Mujibur Rahman Ainun Najib Akhmad Yanuar Fahmi Pamungkas Ali Syahbana Alimuddin Hassan Palawa Alvi Nur Khoirun Nikmah Amin, Ahmad Faiz Makinun Anatasya Wenita Putri Anggraeni, Aulia Anka Luffi Ramdani Annaufal, Azhar Nadhif Ar Rachman, Muhammad Aqil Musthafa Arosyid, Aisyah Putri Arya Dimas Wicaksana Aulia Anggraeni Balqis, Rani Diana Bambang Hermanto Bhuiyan, Nayem Mahmud Budi, Yulifah Salistia Capriandika Putra Susanto Danti, Renita Rizkya Dian Roshanti Efina Amanda Endang Purnama Giri Erik Toga Fami, Amata Gema Parasti Mindara Haidan Angga Kusumah Hanifah, Nurrizkyta Aulia Hidayatin, Nur Husaini, Rizki Ramadhan Husnul Hotimah, Husnul Ida Hayu D Ina Aulia Irma Rasita Gloria Barus Islam , Md. Nasirul Ivan Rachmawan Jayawarsa, A.A. Ketut Jonathan Cristiano Rabika Juliansyah, Rizki Kuntari, Wien Kustanti Nurfitri Laila Sari Masyhur Laili, Roudlotun Nurul Lana Sari Rkt M. Iqbal Ishsani Mahendar, Ibnu Aqil Mala, Said Mannan, Sayed Sajib Mindara, Gema Parasti Mir, MD Atikur Rahman Muhammad Ansor Muhammad Galuh Gumelar Muhammad Nashir Muhammad Yazid Mukhopadhyay, Sudipta Munif, Badrul Nadhifah, Jauza Najla Amelia Putri Nath , Subroto Deb Neneng Aisyah Nia Kurniati Bachtiar Ninis Indriani Nurul Fitriyah Pamungkas , Akhmad Yanuar Fahmi Pipit Hariyono Prasetyawan, Riyan Dwi Priyadi, Budi Puspo Pudji Rahmawati Putri, Anatasya Wenita Putri, Najla Amelia R, Prince Charles Heston Rabika, Jonathan Cristiano Rahman, Md Mehdi Rahmawan, Fajri Andi Rasendriya, Achmad Syahmi Renita Rizkya Danti Rizki Juliansyah Rosuli, Ahmad Rozi, Mohammad Fakhrul Saefudin Zuhri Saidatul Akida Setiady Ibrahim Anwar Sholihin Sholihin Sholihin Sholihin Sholihin Susi Sulandari Tanha, Moutusi Tyanafisya, Aisya Wahyu Hidayat Winda Kustiawan Wulan Agustin, Sindi Candra Yuanto, Hirdes Harlan Yuanto, Rudiyanto