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All Journal JBIO: jurnal biosains (the journal of biosciences) Best Journal (Biology Education, Sains and Technology) JURNAL PENELITIAN KESMASY JURNAL PENELITIAN KEBIDANAN & KESPRO Jurnal Penelitian Farmasi dan Herbal JURNAL PENELITIAN KEPERAWATAN MEDIK International Journal Of Science, Technology & Management (IJSTM) Jurnal Pengabdian Masyarakat Putri Hijau
Syafitri, Anggun
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HUBUNGAN PERSONAL HYGIENE DAN PENGGUNAAN ALAT PELINDUNG DIRI (APD) DENGAN KEJADIAN DERMATITIS KONTAK PADA PETUGAS PENGANGKUT SAMPAH DI TEMPAT PEMBUANGAN AKHIR (TPA) TADUKAN RAG MARBUN, VIKTOR EDYWARD; Sembiring, Johannes; syafitri, anggun
Jurnal Penelitian Keperawatan Medik Vol 6 No 1 (2023): JURNAL PENELITIAN KEPERAWATAN MEDIK
Publisher : Fakultas Keperawatan Institut Kesehatan Deli Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpkm.v6i1.1597

Abstract

Contact dermatitis is dermatitis caused by the presence of irritants or allergens attached to the skin. Epidemiological data in Indonesia shows that 97% of 389 cases of skin disease are contact dermatitis, 66.3% of these cases are irritant contact dermatitis and 33.7% are allergic contact dermatitis. This study aims to determine the relationship between personal hygiene and the use of personal protective equipment (PPE) with the incidence of contact dermatitis in waste collectors at the Tadukan Raga Deli Serdang final disposal site (TPA) in 2023. This study used a quantitative approach with a cross sectional study design. The research was conducted in March 2023 – June 2023 at the Tadukan Raga landfill in Tanjung Morawa. The population of this study were all garbage collectors at the Tadukan Raga TPA. The number of samples in this study were 43 people with the sampling technique being total sampling. Data was collected using a questionnaire with interviews. Data analysis was performed univariately and bivariately with the chi-Square test. The results showed that the variables associated with the incidence of contact dermatitis were: personal hygiene (pvalue=0.004), personal protective equipment (pvalue=0.013). There is a relationship between personal hygiene and the use of personal protective equipment (PPE) with the incidence of contact dermatitis.
FORMULASI DAN UJI EFEKTIVITAS SEDIAAN EKSTRAK ETANOL KULIT PEPAYA (Carica papaya L) SEBAGAI BRIGHTENING GEL SERUM Syafitri, Anggun; Sianipar, Masria Phetheresia; Fantika, Ardhana
Jurnal Penelitian Farmasi Dan Herbal Vol 7 No 1 (2024): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v7i1.1998

Abstract

Facial skin problems that often occur in women and adolescents are dull skin and dark looking skin. Papaya peel (carica papaya L) contains flavonoid compounds which function as antioxidants to brighten the skin. This study aims to formulate papaya peel extract into a serum gel dosage form and observe its effectiveness on the skin of volunteers for 4 weeks of treatment. The research was started by making papaya peel extract which was obtained by maceration method. Then the extract was formulated into serum gel preparations with varying concentrations of gelling agent Carbomer 940 4%, 5%, 6%. The preparations were eval_uated for their physical characteristics, namely organoleptic test, pH test, spreadability test, viscosity test, homogeneity test, irritation test, and test volunteer. The results showed that papaya peel extract could be formulated into a serum gel preparation that was homogeneous, light brown in color, had a spreadability of <5 cm, with a pH <6, and had a viscosity of >2000 cps. Serum gel formula containing Carbomer 940 with a concentration of 6% which has the best effectiveness.
UJI EFEKTIVITAS HIPERKOLESTEROLEMIA EKSTRAK ETANOL DAUN KECIPIR (Psophocarpus tetragonolobus L) PADA TIKUS PUTIH JANTAN (Rattus norvegicus) YANG DIINDUKSI KUNING TELUR BEBEK sianipar, masria phetheresia; Syafitri, Anggun; Sembiring, Pintata
Jurnal Penelitian Farmasi Dan Herbal Vol 7 No 1 (2024): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v7i1.2074

Abstract

This study explored the effectiveness of winged leaf ethanol extract (Psophocarpus tetragonolobus L) in lowering cholesterol levels in male white rats (Rattus norvegicus) induced with duck egg yolk. An experimental method was used to eval__uate the impact of the extract on cholesterol levels, with the aim of providing an alternative treatment of hyperglycoleemia based on natural ingredients. The results show the significant potential of the extract. This research method uses an experimental approach with laboratory design. Male white rats (Rattus norvegicus) were divided into treatment and control groups. Winged leaf ethanol extract was administered to the treatment group, while the control group did not receive the treatment. Cholesterol level measurements were carried out after induction with duck egg yolk, to eval__uate the effectiveness of the extract in lowering cholesterol levels. The results showed that the administration of winged leaf ethanol extract significantly reduced total cholesterol, LDL, and triglyceride levels in induced male white rats. The group that received the highest dose of the extract showed the most favorable reduction in cholesterol levels, close to the effects of simvastatin. These findings indicate the potential of winged leaves as an alternative in the management of hypercholesterolemia. The conclusion of this study showed that winged leaf ethanol extract (Psophocarpus tetragonolobus L) was effective in lowering cholesterol levels in induced male white rats. A dose of 300 mg/kgBB has been shown to be the most effective. Recommendations for further research are to explore different dosage forms and extract concentrations, as well as conduct toxicity studies to ensure their safe use as a hypercholesterolemia therapy.
PENGENALAN PROFESI APOTEKER DAN PENYULUHAN PEMANFAATAN TANAMAN OBAT DAUN SALAM UNTUK PENCEGAHAN DAN PENANGGULANGAN PENYAKIT ASAM URAT PADA MASYARAKAT DI PANCUR BATU KABUPATEN DELI SERDANG Syafitri, Anggun; Rahmi, Sofia; Harahap, Nurul Dahlia; Amar, Ageng AZ; Hayati, Silmi
Jurnal Pengabdian Masyarakat Putri Hijau Vol 5 No 1 (2024): Jurnal Pengabdian Masyarakat Putri Hijau (JPMPH)
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpmph.v5i1.2125

Abstract

Gout is a disease that affects the joints caused by the accumulation of uric acid crystals. High uric acid levels in the body can be caused by high protein levels. The increasing number of elderly people in Indonesia has prompted the government to formulate health policies aimed at improving their quality of life. Uric acid disease, especially gouty arthritis, is one of the common health conditions faced by the elderly, with a high preval_ence in various regions. The accumulation of uric acid crystals, caused by excessive purine consumption and lack of public awareness, is the main trigger for this condition. Frequently used pharmacological therapies have the risk of side effects, so safer alternatives are needed. One of them is the use of salam leaves (Syzygium polyanthum Wight) which contains flavonoids, functions as an antioxidant and inhibitor of the enzyme xanthine oxidase, which is proven to be able to reduce uric acid levels. Through community service activities in Salam Tani Village, Pancur Batu, education about gout and the utilization of salam leaves was carried out. The results showed an increase in community knowledge regarding the benefits of salam leaves in reducing uric acid levels and the role of pharmacists in health services. This education is expected to affect to reducing the preval_ence of gouty arthritis in the elderly.
PELATIHAN MEDIA LEAFLET SECARA HYBRID DAPATi MENINGKATKAN i PENGETAHUAN PENCEGAHAN KOMPLIKASI DIABETIKi DI KECAMATAN TANJUNG MORAWA KABUPATEN DELI SERDANG MARBUN, VIKTOR EDYWARD; sembiring, Johannes; syafitri, anggun
Jurnal Pengabdian Masyarakat Putri Hijau Vol 5 No 2 (2025): Jurnal Pengabdian Masyarakat Putri Hijau (JPMPH)
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpmph.v5i2.2238

Abstract

Diabetes mellitusi (DM) is a chronic disease that can be caused by genetic factors, lack of insulin production by the pancreas, or because the insulin produced does not work optimally. DM can cause various complications, such as disorders of the heart and blood vessels, nervous system, kidneys, and increase the risk of infection. Most DM sufferers already have a fairly good level of knowledge. This activity aims to increase understanding regarding the prevention of diabetes complications in Type 2 DM sufferers in the Tanjung Morawa Health Center work area. Education was provided using leaflet media through a hybrid method, namely directly (offline) and online, to 63 people with Type 2 DM at the Tanjung Morawa Health Center. Before being given education through leaflets and e-leaflets, most respondents had a level of knowledge in the moderate category, namely 28 peoplei (44.44%). After being given educationii, well-knowni majority is 48 people (76.19%). p = 0.000, which means that there is a significanti difference in the level iof knowledgei of the DM in the Tanjung Morawa regency
PENGENALAN TUMBUHAN LOKAL UNTUK KOSMETIK KEPADA GEN Z: EDUKASI FORMULASI SEDIAAN MOISTURIZER EKSTRAK DAUN BENALU DUKU SEBAGAI AGENT PROTECTOR SKIN BARRIER DI SMKS GALANG INSAN MANDIRI Syafitri, Anggun; harnis, zola efa; amar, ageng azhar; tamba, agnes clara; Mardatillah, Hazimah Fithryyah
Jurnal Pengabdian Masyarakat Putri Hijau Vol 5 No 2 (2025): Jurnal Pengabdian Masyarakat Putri Hijau (JPMPH)
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpmph.v5i2.2253

Abstract

This activity aims to introduce local plants, especially duku mistletoe leaves (Dendrophthoe pentandra), as a natural ingredient in the formulation of cosmetic preparations, especially moisturizers, to generation Z. This activity was carried out at Galang Insan Mandiri Vocational School and aims to provide education about the benefits of duku mistletoe leaves as a skin barrier protective agent. With increasing awareness of the importance of sustainability and the use of natural ingredients, it is hoped that this education can encourage the younger generation to prefer local products that are not only safe for skin health but also support the local economy. The outreach methods used include seminars and interactive discussions, which are expected to increase students' knowledge about natural ingredient-based skin care. It is hoped that the results of this activity can make a positive contribution to the development of the natural ingredient-based cosmetics industry in Indonesia.
UJI EFEKTIVITAS EKSTRAK ETANOL DAUN GAGATAN HARIMAU (Vitis gracilisWall) TERHADAP PENAMBAH STAMINA PADA MENCIT JANTAN Syafitri, Anggun; Sianipar, Masria Phetheresia; Agustina, Putri
Jurnal Penelitian Farmasi Dan Herbal Vol 7 No 2 (2025): Jurnal Penelitian Farmasi Dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v7i2.2202

Abstract

Stamina is the ability of human endurance to withstand fatigue within a certain time limit, where activities are carried out with high intensity and always use energy that can be treated with traditional medicine derived from plants. One example of plants that can increase stamina is tiger gagatan leaves which contain flavonoids that can increase the motor activity of mice by inhibiting the absorption of calcium ions entering the sarcoplasmic reticulum after that with the obstacle causing high calcium ion levels in sarcoplasm and containing tonic effects. The purpose of the study was to determine the effect of giving tiger gagatan leaf extract in increasing stamina compared to caffeine. This research was conducted by experimental method, samples were extracted maceration using 96% ethanol solvent and concentrated with a rotary evaporator. Using 25 mice and divided into 5 groups. The control group was negative CMC-Na 0.5%, the control group positive for caffeine 0.13mg/kgBB, EDGH with a dose of 50mg/kgBB, EDGH with a dose of 100mg/kgBB, EDGH with a dose of 200mg/kgBB. Then observed the endurance time of mouse stamina and calculated the average physical endurance time of mice by swimming method. From the results of the study that the EDGH dose of 200mg/kgBB had optimal effectiveness close to the positive control group with swimming endurance time of 52.18 minutes, while EDGH with a dose of 100mg / kggBB showed a physical endurance time of mice of 49.07 minutes, and EDGH 50mg / kg BB showed a physical endurance time of mice of 48.24 minutes. So it can be concluded that tiger gagatan leaf extract at a dose of 200mg/kgBB has an effectiveness equivalent to caffeine in increasing stamina against male white mice.
PENGEMBANGAN FACEMIST KOMBINASI EKSTRAK DAUN BIDARA (Ziziphus spina cristi (L.) Desf) DAN DAUN BENALU DUKU (Dendrophthoe pentandra (L.) Miq ) SEBAGAI ANTIOKSIDAN PADA KULIT WAJAH anggara, Elysa; syafitri, anggun; sari, tio ranti
Jurnal Penelitian Farmasi Dan Herbal Vol 7 No 2 (2025): Jurnal Penelitian Farmasi Dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v7i2.2257

Abstract

The skin needs antioxidant compounds that can ward off free radicals caused by several factors, one of which is air pollution. Bidara leaves (Zizipus spina Cristi (L) Desf) and benalu duku leaves (Dendrophthoe pentandra (L.) Miq) contain flavonoid compounds that function as antioxidants that can ward off free radicals. This study aims to formulate bidara leaf extract and benalu duku leaf into the form of Facemist preparation and determine the best Facemist product formula with the addition of bidara leaf extract, benalu leaf, and a combination of two extracts through antioxidant activity parameters. The antioxidant activity test was carried out using the DPPH (1,1-dipenyl-2-picrylhydrazyl) method. The Facemist sample was formulated into a Facemist with concentration variations: F1 : EEDB 5%, F2 : EEDBD : 5%, F3 : EEDB : 2.5% EEDBD 2.5%, F4 : EEDB : 5% EEDBD : 5%, F5 : EEDB : 10% EEDBD : 10%. Facemist preparations are eval_uated for their physical characteristics, namely organoleptic test, homogeneity test, pH test, viscosity test, dry time test, irritation test. The results showed that Facemist was a combination of bidara leaf extract and benalu duku leaf homogeneous, pH <7, had a viscosity value of <500 cps, a good drying time of <5 minutes and did not cause irritation to the skin. The formulation of Facemist preparation that has the best antioxidant activity value is F5 with antioxidant activity (IC50) of 58.33 ppm in the strong category.
The Effect of Dendrophthoe pentandra (L.) Miq Ethanol Extract on Malondialdehyde (MDA) in Hyperglycemic Rats Syafitri, Anggun; Yuandani, Yuandani; Widyawati, Tri
International Journal of Science, Technology & Management Vol. 4 No. 2 (2023): March 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i2.758

Abstract

Dendrophthoe pentandra (L.) Miq is a parasitic plant with medicinal potential found in 3000 other plant species. The duku parasite is usually considered a parasite on the duku plant and is often discarded because it is thought to interfere with the growth of the duku plant. The purpose of this study was to see the effect of the duku parasite leaf extract on the reduction of malondialdehyde (MDA) in hyperglycemic rats. MDA levels were measured by thiobarbituric acid-reactive substance (TBARS) assay with doses of duku mistletoe leaf ethanol extract of 400, 200, and 100 mg/kg BW. MDA levels were analysed using rat blood plasma, which was measured using a spectrophotometer at a wavelength of 532 nm. Oral administration of EEDBD 400, 200, and 100 mg/kg BW reduced MDA levels in hyperglycemic rats. However, only EEDBD 400 mg/kg BW showed a significant difference between the negative control (CMC-Na), but with glibenclamide and the normal groups, there was no significant difference.
Uji Efektivitas Anti Diabetes Ekstrak Etanol Daun Ulam Raja (Cosmos caudatus K.) Pada Tikus Jantan Putih (Galur wistar) Yang Diinduksi Streptozotocin Dan Nicotinamide Syafitri, Anggun; Rahmah, Siti
BEST Journal (Biology Education, Sains and Technology) Vol 8, No 2 (2025): September 2025
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v8i2.13054

Abstract

Diabetes melitus adalah gangguan metabolik yang ditandai dan diidentifikasi oleh kadar glukosa darah yang tinggi atau dikenal sebagai hiperglikemia. Kondisi ini berkaitan dengan berbagai kelainan dalam metabolisme karbohidrat, lemak, dan protein yang disebabkan oleh gangguan sekresi insulin akibat kerusakan sel beta pankreas, penurunan sensitivitas insulin, atau kombinasi keduanya. Namun, penggunaan obat sintetis secara terus-menerus juga berisiko menyebabkan berbagai efek samping lainnya, seperti gangguan saluran pencernaan dan hati, edema perifer, sakit kepala, batuk, hiperkalemia, gangguan rasa, apnea tidur, disfungsi ereksi, dan angioedema. Oleh karena itu, alternatif terapi yang lebih aman berdasarkan bahan alami sangat dibutuhkan. Salah satu tanaman yang berpotensi sebagai antidiabetes adalah daun king ulam (Cosmos cauvdatus K.), yang mengandung senyawa flavonoid seperti quercetin dan kaemferol. Senyawa ini bersifat antioksidan, mampu melindungi sel beta pankreas, dan meningkatkan penyerapan glukosa ke dalam otot melalui aktivasi jalur AMPK. Studi ini bertujuan untuk menganalisis efektivitas ekstrak etanol daun king ulam (Cosmos cauvdatus K) sebagai antidiabetes pada tikus yang diinduksi streptozotocin dan nikotinamida, membandingkan efektivitasnya dengan glibenklamida, dan menganalisis dosis ekstrak etanol daun king ulam yang paling efektif sebagai antidiabetes. Penelitian ini dilakukan dengan metode eksperimental pada 25 tikus jantan putih (galur Wistar) yang dibagi menjadi 5 kelompok perlakuan, yaitu kontrol negatif (Na-CMC) 0,5%, kontrol positif (Glibenklamida 0,45 mg/kgBB), EEVDUR dosis 100 mg/kgBB, EEVDUR 200 mg/kgBB, dan EEVDUR 400 mg/kgBB. Hasil analisis statistik menunjukkan bahwa EEVDUR mampu menurunkan kadar glukosa darah secara signifikan pada tikus dan memiliki efektivitas yang setara dengan glibenklamida. Dosis EEVDUR 400 mg/kgBB menunjukkan efek paling optimal sebagai antidiabetes. Hasil ini mendukung potensi penggunaan daun king ulam sebagai terapi alternatif yang lebih aman dalam pengelolaan diabetes melitus
Co-Authors Amar, Ageng AZ amar, ageng azhar Anggara, Elysa Atika Patnisuri Bintang Lubis Br Barus, Lidia Klorida Bunga Rimta Barus Delisma Marsauli Simorangkir Delisma Simorangkir Efrata Sembiring Elysa Elysa Fantika, Ardhana Harahap, Nurul Dahlia Harnis, Zola Efa Hayati, Silmi Jhan Saberlan Purba JOHANNES SEMBIRING Laia, Sardamai Linta Meliala MARBUN, VIKTOR EDYWARD Mardatillah, Hazimah Fithryyah Masria Phetheresia Sianipar Maulida Rahma Pintata Sembiring PUJI LESTARI Putri Agustina Rahmi, Sofia sari, tio ranti Sembiring, Johannes Sianipar, Masria Phetheresia Silmi Hayati Siti Rahmah Sitio, Sri Sudewi Pratiwi Sofia Eliasari Br Bangun Sofia Rahmi Tambusai sulasmi sulasmi Tamba, Agnes Clara Tri Widyawati, Tri Wahyudi Wahyudi Yuandani Yunita Syaputri Damanik