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All Journal Best Journal (Biology Education, Sains and Technology) Jurnal Penelitian Farmasi dan Herbal JURNAL PENELITIAN KEPERAWATAN MEDIK International Journal Of Science, Technology & Management (IJSTM) Jurnal Pengabdian Masyarakat Putri Hijau
Syafitri, Anggun
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PENGENALAN PROFESI APOTEKER DAN PENYULUHAN PEMANFAATAN TANAMAN OBAT DAUN SALAM UNTUK PENCEGAHAN DAN PENANGGULANGAN PENYAKIT ASAM URAT PADA MASYARAKAT DI PANCUR BATU KABUPATEN DELI SERDANG Syafitri, Anggun; Rahmi, Sofia; Harahap, Nurul Dahlia; Amar, Ageng AZ; Hayati, Silmi
Jurnal Pengabdian Masyarakat Putri Hijau Vol 5 No 1 (2024): Jurnal Pengabdian Masyarakat Putri Hijau (JPMPH)
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpmph.v5i1.2125

Abstract

Gout is a disease that affects the joints caused by the accumulation of uric acid crystals. High uric acid levels in the body can be caused by high protein levels. The increasing number of elderly people in Indonesia has prompted the government to formulate health policies aimed at improving their quality of life. Uric acid disease, especially gouty arthritis, is one of the common health conditions faced by the elderly, with a high preval_ence in various regions. The accumulation of uric acid crystals, caused by excessive purine consumption and lack of public awareness, is the main trigger for this condition. Frequently used pharmacological therapies have the risk of side effects, so safer alternatives are needed. One of them is the use of salam leaves (Syzygium polyanthum Wight) which contains flavonoids, functions as an antioxidant and inhibitor of the enzyme xanthine oxidase, which is proven to be able to reduce uric acid levels. Through community service activities in Salam Tani Village, Pancur Batu, education about gout and the utilization of salam leaves was carried out. The results showed an increase in community knowledge regarding the benefits of salam leaves in reducing uric acid levels and the role of pharmacists in health services. This education is expected to affect to reducing the preval_ence of gouty arthritis in the elderly.
PELATIHAN MEDIA LEAFLET SECARA HYBRID DAPATi MENINGKATKAN i PENGETAHUAN PENCEGAHAN KOMPLIKASI DIABETIKi DI KECAMATAN TANJUNG MORAWA KABUPATEN DELI SERDANG MARBUN, VIKTOR EDYWARD; sembiring, Johannes; syafitri, anggun
Jurnal Pengabdian Masyarakat Putri Hijau Vol 5 No 2 (2025): Jurnal Pengabdian Masyarakat Putri Hijau (JPMPH)
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpmph.v5i2.2238

Abstract

Diabetes mellitusi (DM) is a chronic disease that can be caused by genetic factors, lack of insulin production by the pancreas, or because the insulin produced does not work optimally. DM can cause various complications, such as disorders of the heart and blood vessels, nervous system, kidneys, and increase the risk of infection. Most DM sufferers already have a fairly good level of knowledge. This activity aims to increase understanding regarding the prevention of diabetes complications in Type 2 DM sufferers in the Tanjung Morawa Health Center work area. Education was provided using leaflet media through a hybrid method, namely directly (offline) and online, to 63 people with Type 2 DM at the Tanjung Morawa Health Center. Before being given education through leaflets and e-leaflets, most respondents had a level of knowledge in the moderate category, namely 28 peoplei (44.44%). After being given educationii, well-knowni majority is 48 people (76.19%). p = 0.000, which means that there is a significanti difference in the level iof knowledgei of the DM in the Tanjung Morawa regency
PENGENALAN TUMBUHAN LOKAL UNTUK KOSMETIK KEPADA GEN Z: EDUKASI FORMULASI SEDIAAN MOISTURIZER EKSTRAK DAUN BENALU DUKU SEBAGAI AGENT PROTECTOR SKIN BARRIER DI SMKS GALANG INSAN MANDIRI Syafitri, Anggun; harnis, zola efa; amar, ageng azhar; tamba, agnes clara; Mardatillah, Hazimah Fithryyah
Jurnal Pengabdian Masyarakat Putri Hijau Vol 5 No 2 (2025): Jurnal Pengabdian Masyarakat Putri Hijau (JPMPH)
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpmph.v5i2.2253

Abstract

This activity aims to introduce local plants, especially duku mistletoe leaves (Dendrophthoe pentandra), as a natural ingredient in the formulation of cosmetic preparations, especially moisturizers, to generation Z. This activity was carried out at Galang Insan Mandiri Vocational School and aims to provide education about the benefits of duku mistletoe leaves as a skin barrier protective agent. With increasing awareness of the importance of sustainability and the use of natural ingredients, it is hoped that this education can encourage the younger generation to prefer local products that are not only safe for skin health but also support the local economy. The outreach methods used include seminars and interactive discussions, which are expected to increase students' knowledge about natural ingredient-based skin care. It is hoped that the results of this activity can make a positive contribution to the development of the natural ingredient-based cosmetics industry in Indonesia.
UJI EFEKTIVITAS EKSTRAK ETANOL DAUN GAGATAN HARIMAU (Vitis gracilisWall) TERHADAP PENAMBAH STAMINA PADA MENCIT JANTAN Syafitri, Anggun; Sianipar, Masria Phetheresia; Agustina, Putri
Jurnal Penelitian Farmasi Dan Herbal Vol 7 No 2 (2025): Jurnal Penelitian Farmasi Dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v7i2.2202

Abstract

Stamina is the ability of human endurance to withstand fatigue within a certain time limit, where activities are carried out with high intensity and always use energy that can be treated with traditional medicine derived from plants. One example of plants that can increase stamina is tiger gagatan leaves which contain flavonoids that can increase the motor activity of mice by inhibiting the absorption of calcium ions entering the sarcoplasmic reticulum after that with the obstacle causing high calcium ion levels in sarcoplasm and containing tonic effects. The purpose of the study was to determine the effect of giving tiger gagatan leaf extract in increasing stamina compared to caffeine. This research was conducted by experimental method, samples were extracted maceration using 96% ethanol solvent and concentrated with a rotary evaporator. Using 25 mice and divided into 5 groups. The control group was negative CMC-Na 0.5%, the control group positive for caffeine 0.13mg/kgBB, EDGH with a dose of 50mg/kgBB, EDGH with a dose of 100mg/kgBB, EDGH with a dose of 200mg/kgBB. Then observed the endurance time of mouse stamina and calculated the average physical endurance time of mice by swimming method. From the results of the study that the EDGH dose of 200mg/kgBB had optimal effectiveness close to the positive control group with swimming endurance time of 52.18 minutes, while EDGH with a dose of 100mg / kggBB showed a physical endurance time of mice of 49.07 minutes, and EDGH 50mg / kg BB showed a physical endurance time of mice of 48.24 minutes. So it can be concluded that tiger gagatan leaf extract at a dose of 200mg/kgBB has an effectiveness equivalent to caffeine in increasing stamina against male white mice.
PENGEMBANGAN FACEMIST KOMBINASI EKSTRAK DAUN BIDARA (Ziziphus spina cristi (L.) Desf) DAN DAUN BENALU DUKU (Dendrophthoe pentandra (L.) Miq ) SEBAGAI ANTIOKSIDAN PADA KULIT WAJAH anggara, Elysa; syafitri, anggun; sari, tio ranti
Jurnal Penelitian Farmasi Dan Herbal Vol 7 No 2 (2025): Jurnal Penelitian Farmasi Dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v7i2.2257

Abstract

The skin needs antioxidant compounds that can ward off free radicals caused by several factors, one of which is air pollution. Bidara leaves (Zizipus spina Cristi (L) Desf) and benalu duku leaves (Dendrophthoe pentandra (L.) Miq) contain flavonoid compounds that function as antioxidants that can ward off free radicals. This study aims to formulate bidara leaf extract and benalu duku leaf into the form of Facemist preparation and determine the best Facemist product formula with the addition of bidara leaf extract, benalu leaf, and a combination of two extracts through antioxidant activity parameters. The antioxidant activity test was carried out using the DPPH (1,1-dipenyl-2-picrylhydrazyl) method. The Facemist sample was formulated into a Facemist with concentration variations: F1 : EEDB 5%, F2 : EEDBD : 5%, F3 : EEDB : 2.5% EEDBD 2.5%, F4 : EEDB : 5% EEDBD : 5%, F5 : EEDB : 10% EEDBD : 10%. Facemist preparations are eval_uated for their physical characteristics, namely organoleptic test, homogeneity test, pH test, viscosity test, dry time test, irritation test. The results showed that Facemist was a combination of bidara leaf extract and benalu duku leaf homogeneous, pH <7, had a viscosity value of <500 cps, a good drying time of <5 minutes and did not cause irritation to the skin. The formulation of Facemist preparation that has the best antioxidant activity value is F5 with antioxidant activity (IC50) of 58.33 ppm in the strong category.
The Effect of Dendrophthoe pentandra (L.) Miq Ethanol Extract on Malondialdehyde (MDA) in Hyperglycemic Rats Syafitri, Anggun; Yuandani, Yuandani; Widyawati, Tri
International Journal of Science, Technology & Management Vol. 4 No. 2 (2023): March 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i2.758

Abstract

Dendrophthoe pentandra (L.) Miq is a parasitic plant with medicinal potential found in 3000 other plant species. The duku parasite is usually considered a parasite on the duku plant and is often discarded because it is thought to interfere with the growth of the duku plant. The purpose of this study was to see the effect of the duku parasite leaf extract on the reduction of malondialdehyde (MDA) in hyperglycemic rats. MDA levels were measured by thiobarbituric acid-reactive substance (TBARS) assay with doses of duku mistletoe leaf ethanol extract of 400, 200, and 100 mg/kg BW. MDA levels were analysed using rat blood plasma, which was measured using a spectrophotometer at a wavelength of 532 nm. Oral administration of EEDBD 400, 200, and 100 mg/kg BW reduced MDA levels in hyperglycemic rats. However, only EEDBD 400 mg/kg BW showed a significant difference between the negative control (CMC-Na), but with glibenclamide and the normal groups, there was no significant difference.
Uji Efektivitas Anti Diabetes Ekstrak Etanol Daun Ulam Raja (Cosmos caudatus K.) Pada Tikus Jantan Putih (Galur wistar) Yang Diinduksi Streptozotocin Dan Nicotinamide Syafitri, Anggun; Rahmah, Siti
BEST Journal (Biology Education, Sains and Technology) Vol 8, No 2 (2025): September 2025
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v8i2.13054

Abstract

Diabetes melitus adalah gangguan metabolik yang ditandai dan diidentifikasi oleh kadar glukosa darah yang tinggi atau dikenal sebagai hiperglikemia. Kondisi ini berkaitan dengan berbagai kelainan dalam metabolisme karbohidrat, lemak, dan protein yang disebabkan oleh gangguan sekresi insulin akibat kerusakan sel beta pankreas, penurunan sensitivitas insulin, atau kombinasi keduanya. Namun, penggunaan obat sintetis secara terus-menerus juga berisiko menyebabkan berbagai efek samping lainnya, seperti gangguan saluran pencernaan dan hati, edema perifer, sakit kepala, batuk, hiperkalemia, gangguan rasa, apnea tidur, disfungsi ereksi, dan angioedema. Oleh karena itu, alternatif terapi yang lebih aman berdasarkan bahan alami sangat dibutuhkan. Salah satu tanaman yang berpotensi sebagai antidiabetes adalah daun king ulam (Cosmos cauvdatus K.), yang mengandung senyawa flavonoid seperti quercetin dan kaemferol. Senyawa ini bersifat antioksidan, mampu melindungi sel beta pankreas, dan meningkatkan penyerapan glukosa ke dalam otot melalui aktivasi jalur AMPK. Studi ini bertujuan untuk menganalisis efektivitas ekstrak etanol daun king ulam (Cosmos cauvdatus K) sebagai antidiabetes pada tikus yang diinduksi streptozotocin dan nikotinamida, membandingkan efektivitasnya dengan glibenklamida, dan menganalisis dosis ekstrak etanol daun king ulam yang paling efektif sebagai antidiabetes. Penelitian ini dilakukan dengan metode eksperimental pada 25 tikus jantan putih (galur Wistar) yang dibagi menjadi 5 kelompok perlakuan, yaitu kontrol negatif (Na-CMC) 0,5%, kontrol positif (Glibenklamida 0,45 mg/kgBB), EEVDUR dosis 100 mg/kgBB, EEVDUR 200 mg/kgBB, dan EEVDUR 400 mg/kgBB. Hasil analisis statistik menunjukkan bahwa EEVDUR mampu menurunkan kadar glukosa darah secara signifikan pada tikus dan memiliki efektivitas yang setara dengan glibenklamida. Dosis EEVDUR 400 mg/kgBB menunjukkan efek paling optimal sebagai antidiabetes. Hasil ini mendukung potensi penggunaan daun king ulam sebagai terapi alternatif yang lebih aman dalam pengelolaan diabetes melitus
UJI EFEKTIVITAS ANTIDIABETES EKSTRAK ETANOL DAUN YAKON (Smallanthus sonchifolius.) PADA TIKUS JANTAN (Galur Wistar) YANG DIINDUKSI NICOTINAMIDE DAN STREPTOZOTOCIN Syafitri, Anggun; Mardatilah, Hazimah Fitriyah; Kurniawan, Nanda
Jurnal Penelitian Farmasi Dan Herbal Vol. 8 No. 2 (2026): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Diabetes mellitus is a chronic metabolic disease characterized by hyperglycemia due to impaired insulin secretion or action. The use of synthetic antidiabetic drugs has a variety of side effects, so the search for alternatives from natural ingredients is constantly being carried out. Yakon leaves (Smallanthus sonchifolius) are known to contain flavonoids such as quercetin which have antidiabetic activity through antioxidant mechanisms and inhibition of glucose-decomposing enzymes. To determine the effectiveness of yakon leaf ethanol extract (EEDY) in lowering blood glucose levels (KGD) in male rats of the Wistar strain induced by nicotinamide and streptozotocin, and to compare it with the positive control of glibenclamide. The experimental study used 25 mice divided into 5 groups: negative control (Na-CMC), positive control (glycenchalamide 0.45 mg/kgBB). and three treatment groups with EEDY doses of 100, 200, and 400 mg/kgBB. Induction of diabetes is carried out with streptozotocin and nicotinamide. KGD was measured before and after treatment and was performed on days 4, 8, 12, 16, 20, 24, and 28. The administration of EEDY showed a significant reduction in KGD (p<0.05) compared to negative controls. The dose of 400 mg/kgBB provides the greatest decreasing effect, approaching the effectiveness of glibenclamide. Statistical analysis showed that there was a significant difference between the negative control group and the treatment.
Co-Authors Amar, Ageng AZ amar, ageng azhar Anggara, Elysa Atika Patnisuri Br Barus, Lidia Klorida Delisma Simorangkir Fantika, Ardhana Harahap, Nurul Dahlia Harnis, Zola Efa Hayati, Silmi Laia, Sardamai Linta Meliala MARBUN, VIKTOR EDYWARD Mardatilah, Hazimah Fitriyah Mardatillah, Hazimah Fithryyah Masria Phetheresia Sianipar Nanda Kurniawan Pintata Sembiring PUJI LESTARI Putri Agustina Rahmi, Sofia sari, tio ranti Sembiring, Johannes Sianipar, Masria Phetheresia Siti Rahmah Sofia Eliasari Br Bangun Tamba, Agnes Clara Tri Widyawati, Tri Yuandani