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Fajar Arianto
Laboratorium Fisika Radiasi Dan Fisika Medik, Departemen Fisika Universitas Diponegoro, Jl. Prof. Soedarto SH Tembalang Semarang
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Journal : Physics Communication

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Determination of Neutron Flux in Brain Cancer Boron Neutron Capture Therapy Using Monte Carlo Simulation Arianto, Fajar; Handayani, Liska Tri; Budi, Wahyu Setia; Basuki, Prasetyo
Physics Communication Vol 6, No 2 (2022): August 2022
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/physcomm.v6i2.40277

Abstract

Boron Neutron Capture Therapy (BNCT) is a relatively safer technology for killing cancer cells, one of which is the Glioblastoma multiforme. One of the main components of the BNCT equipment is the collimator which functions as an exit point for epithermal neutron particles that hit cancer cells. In addition to the experimental method, BNCT research can be carried out by modeling, including using the MCNPX software based on the Monte Carlo Method. This research aimed to determine the flux distribution of fast and epithermal neutrons and the dose rate of fast neutrons and gamma that hit the target cancer cells in the phantom head of ORNL MIRD. Modeling using the MCNPX software has three main parts: cell cards, surface cards, and data cards. A tally is used on the data card to calculate the neutron flux. Based on the calculation of the modeling results, the flux of epithermal neutron is 2.87 x 109 n/cm2.s. The dose ratio of the epithermal to the fast neutron flux is 2.29 x 10-14 Gy.cm2/n. Then, the balance of the dose rate of the epithermal to the gamma is 1.64 x 10-14 Gy.cm2/n, and the ratio of epithermal to thermal neutron flux is 0.004. In this study, the epithermal neutron flux hitting the target cancer cells in cell target was moderated at 4 cm so that at a depth of 8 cm, the energy was converted into thermal neutrons. Based on the analysis of the results, it can be concluded that the neutron flux that will interact with cancer tissue is thermal neutrons, not epithermal neutron flux.
Co-Authors ABDUL MANAF Abror, Sirojuddin Achmad Sjaifudin Tayibnapis Ade Ika Susan Agusti, Fiqrie Restia Agustina, Sheila ALFINA RAHMAWATI, DIAN Ali Khumaeni ALIM SUMARNO AMALIA WAHYUNINGTYAS, ISTI Andi Kristanto Andi Mariono Andi Wibowo Kinandana Anitasari, Emi Anwar Usman Armilah, Mila Siti Asep Yoyo Wardaya Auliyani, Chaeriyatun Nissa Azizul Khakim, Azizul Bachri, Bachtiar S. Bachri, Bachtiar Sjaiful Chrisdian, Viddo Citra Fitri Kholidya Dahurandi, Keristian Darliawati, Herli Darmanto Darmanto Dewantari, Aditya Dewantoro, Muhammad Dhiaulhaq, Shifiyan Ahmad Dhyan Prastiwi Emi Anitasari Erma Prihastanti Fatah Yasin FAUZI ADHIM, MUHAMMAD Febry Fitriani FITRIA, ZOIMATUL Fuad Anwar, Fuad Gunawan Gunawan Hadi Prasetyo Utomo Hamdiyah, Heni Handayani, Liska Tri Handayani, Nita Hariyati, Mutty Hasan, Siti Nurjannah Hasnawati, Lina Hayati, Widia Herli Darliawati Hisyam, Hisyam Husni Mubarok Iis Nurhasanah Isa Ansori Islami, Jundu Muhammad Mufakkirul Istiqomah Istiqomah Juari, S K Sofjan Firdausi khusnul khotimah Kusumandari, Kusumandari Liska Tri Handayani M.A. Muazar Habibi Maharani, Rosy Puspa Martadi, Martadi Maureen, Irena Y. Medina, Alfiarani Meisa Diningrat, Syaiputra Wahyuda Moh Jazuli, Moh Muhammad Adrian Lathif Muhammad Nur Muhammad Nur Muhammad Nur Muhammad Nur Mustaji Mustaji, Mustaji Ngurah Ayu Ketut Umiati Novan Prawira, Dyon Nufus, Asyifa’un Nur, Muhammad Nurhasanah Nurhasanah Nurul Azmi, Nurul Nuryati, Dwi Wahyu Nurzanah, Salsabilla Choerunnisa Pandji Triadyaksa Prasetyo Basuki Prastiwi, Dhyan Pratama Jujur Wibawa PUSPITA WIRASARI, ENGGAL Putra, Riko Putri, Weni Antari Ramadhan, Avinda Zakcy Rayhani, Fauziah Rety, Dahniarti Cahyani Riyatun, Riyatun RR. Ella Evrita Hestiandari Rusjiono Rusjiono sahamudin, Sahamudin Saraslifah Saraslifah Setyaedhi, Hari Sugiharto Shofiana, Fahlulia Rahma Sholehah Aisyah Siti Khodijah Siti Masitoh Suharyana Suharyana Sumariyah Sumariyah Susarno, Lamijan Hadi SYAIPUTRA WAHYUDA MEISA DINING Tayibnapis, Achmad Sjaifudin Terananda, Nabila Zuhroh Ukhti Nurohma Rizki Utari Dewi Utari Utari Very Richardina Wahyu Setia Budi Waode Hamsia, Waode Wienda Intan Permatasari YATIM RIYANTO Yudha Arman Zaenul Muhlisin Zahroh, Mihnatuz