Article Per Year (5 Year)
p-Index From 2020 - 2025
2.062
P-Index
This Author published in this journals
All Journal HAYATI Journal of Biosciences Jurnal Agronomi Indonesia (Indonesian Journal of Agronomy) Jurnal Gizi dan Pangan Jurnal Fitopatologi Indonesia Jurnal Teknologi Dan Industri Pangan Jurnal Akuakultur Indonesia Jurnal Farmasi Udayana CHEMISTRY PROGRESS Jurnal Pendidikan Bahasa dan Sastra Indonesia Undiksha Microbiology Indonesia BIOTROPIA - The Southeast Asian Journal of Tropical Biology Current Biochemistry The Journal of Pure and Applied Chemistry Research Indonesian Journal of Biotechnology BERITA BIOLOGI ANNALES BOGORIENSES FITOFARMAKA: Jurnal Ilmiah Farmasi Menara Perkebunan Jurnal Jamu Indonesia Sainstek : Jurnal Sains dan Teknologi Jurnal Pusat Inovasi Masyarakat Jurnal Ilmu Kehutanan Molekul: Jurnal Ilmiah Kimia Journal of The Indonesian Society of Integrated Chemistry Indonesian Journal of Jamu
I MADE ARTIKA
Department Of Biochemistry, Faculty Of Mathematics And Natural Sciences, Darmaga Campus, IPB University, Bogor, 16680, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Social Sciences Veterinary Other

Published : 61 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : CHEMISTRY PROGRESS

 1 
PROPOLIS SEBAGAI ALTERNATIF BAHAN ANTIKARIES GIGI Hasan, A. E. Zainal; Artika, I Made; K, Popi A; Lasmiyanti, Metty
CHEMISTRY PROGRESS Vol 4, No 1 (2011)
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/cp.4.1.2011.26504

Abstract

ABSTRACTZainal Hasan A. E. et al., 2011. Propolis as alternative additive anti-cariesPeriodontal disease included dental caries still the major problem in the world. Usually commercial tooth pastecontains fluoride which has an important role to prevent tooth from damage. Contain fluoride overdose causedfluorosis, bone damage and anemia. Therefore, the propolis was being tested as alternative additive anti cariesto prevent the growth of cariogenics bacteria (Streptococcus mutans). This research studied propolis activityantibacterial and the minimum inhibitory concentration (MIC) of propolis against S. mutans.Ethanolic extract of propolis (EEP) contained various bioactive compound such as flavonoid, tannine, alkaloid,triterpenoid and saponin based on phytochemistry analyses. The extract effectivities are 96.5% relative to thepropolis X, 41.04% relative to amphicillin 10 mg/ml and 240.57% relative to NaF 3000 ppm. The MIC of theextract is 3.13%. Therefore, propolis extract can be used asa additive anti caries element in tooth paste.Statistical analyses showed that 100% EEP, X propolis and amphicillin 10 mg/ml had the ability to decrease S.mutans colonyKeywords : propolis, anti-caries, ethanolic extract
PENERAPAN TEKNOLOGI NANOPARTIKEL UNTUK SEDIAAN OBAT (ANTIBIOTIK BERBASIS BAHAN ALAM, PROPOLIS TRIGONA SPP) Hasan, H. A. E. Zainal; Artika, I Made; Fahri, Vita Rosaline; Sari, Nurmala
CHEMISTRY PROGRESS Vol 5, No 1 (2012)
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/cp.5.1.2012.655

Abstract

Zainal Hasan dkk., 2012. Penerapan teknologi nanopartikel untuk sediaan obat (antibiotik berbasis bahanalam, Propolis Trigona spp.). Propolis Trigona spp telah diteliti dapat menghambat pertumbuhan bakteri patogen seperti Escherichia coli.Senyawa Flavonoid yang terkandung dalam propolis diduga berperan sebagai antibakteri. Jika ukuran partikelmakin kecil maka luas permukaan partikel makin besar sehingga laju dari larutan semakin meningkat danmempercepat penyerapan obat melalui peredaran darah sehingga efek terapeutiknya lebih cepat tercapai.Salah satu cara yang dapat dilakukan untuk memperkecil ukuran partikel guna meningkatkan kelarutan danpenyerapan suatu sediaan farmasi adalah dengan menggunakan nanoteknologi.Pada penelitian ini telah dirancang sediaan propolis dalam bentuk nanopartikel. Tujuan penelitian ini adalahmembuat nanopartikel dari propolis Trigona spp. Proses pembuatan nanopropolis yaitu dengan cara penyalutandan homogenizer pada kecepatan tinggi. Telah dilakukan uji aktivitas dari nanopartikel propolis sebagaiantibakteri dan menentukan konsentrasi hambat tumbuh minimum propolis nanopartikel terhadap bakteriEscherichia coli secara in vitro. Dari hasil penelitian ini menunjukkan bahwa propolis Trigona spp dapat dibuatdalam bentuk nanopartikel. Hasil Scanning Electron Microscopy menunjukkan adanya ukuran diameternanopropolis sebesar 100 ? 322 nm. Hasil uji aktivitas antibakteri menunjukkan pada konsentrasi 10% - 0,02%nanopropolis aktif terhadap E. coli sedangkan propolis bukan nanopartikel aktif sampai konsentrasi 0,15%.Dengan demikian KHTM ?propolis bukan nanopartikel? dicapai pada konsentrasi 0,15%, sedangkannanopropolis KHTM nya lebih rendah dari 0,02%. Propolis nanopartikel lebih efektif dibandingkan ?propolisbukan nanopartikel? dalam menghambat pertumbuhan E. coli.Kata kunci : propolis, nanopartikel, E.coli, KHTMZainal Hasan et al., 2011. Application of nanoparticle technology for medicine preparate (Antibiotic base onnatural product, Propolis Trigona spp.). Trigona spp propolis has been evaluated can inhibit Escherichia coli. Flavonoid in propolis suggested act asantibacterial. If particle size smaller, then its surface area is bigger, so the rate of drugs absorption wereincreased trough blood circulation and its therapy effect can be achieved faster. One of resize way to reduceparticle size to increase its solubility dan absorption pharmaceutical is using nanotechnology.This research has been designed propolis in nanoparticle size. The aims of this research is to makenanoparticle propolis from Trigona spp. The process to make nanopropolis was covered it and homogenize inhigh speed. Nanopropolis activity evaluation has been done as antibacterial and determined its minimuminhibition concentration on Escherichia coli (in vitro). Trigona spp propolis can be made to nanoparticle. ElectronMicroscopy scanning shows nanopropolis diameter was 100 ? 322 nm. Antibacterial activity evaluation showson nanoproposis concentration 10% - 0,02% active on E. Coli, although nonnanopropolis active onconcentration 0,15%. Nanopropolis is more effective than non nanopropolis to inhibit E. coli.Keywords : propolis, nanopartikel, E.coli, KHTM
Co-Authors . SURYANI A. E. Zainal Hasan AA Sudharmawan, AA Abdul Choliq ADINDA VIRGINIA DWI SETYO Agung Eru Wibowo AHMAD ENDANG ZAINAL HASAN AHMAD ENDANG ZAINAL HASAN Ahmad Sulaeman Akhmad Endang Zainal Hasan Amanda, Nisa Widya AMIN FATONI Andani, Gita Putri Andita Fitri Mutiara Rizki, Andita Fitri Mutiara Antonius Padua Ratu Apipah Aprianti Apon Zaenal Mustopa APON ZAENAL MUSTOPA Arya Arendra Asri Sulfianti Azmi Azhari Azmi Azhari, Azmi Azmi, Wihda Aisarul BUGI RATNO BUDIARTO DEDI JUSADI Denny Irawati Desi Purwaningsih Dewi Sukma Dhani Luthfi Ramadhani DIMAS ANDRIANTO Djarot Sasongko Hami Seno Dodi Safari Dodi Safari Dodi Safari Dodi Safari Dwi N. Susilowati Dzihan Dinar Rabani Eliza Halim Erismar Amri Erlank Bagjavicenna Erna Puspasari Evi Nur Qolbaini Fatriani, Rizka Fina Febrianti Firda DIMAWARNITA Fri Rahmawati Gusnia Meilin Gholam Gusnia Meilin Gholam Gusnia Meilin Gholam H. A. E. Zainal Hasan Hafizh Zahra Hani 'Athiyya Rafi Hardinsyah Harsana, Ngurah HARTUTIK EKA SUSANTI HARYANTO SUSILO Hasim - HASIM DANURI Hayatul Rahmi Herti Sugiarti Herti Sugiarti, Herti Hyakansa HANIF Ifa Manzila Iman Akhyar Firdausy Iman Rusmana Inawati Inawati Jajang Suhyana K, Popi A Kurnia Agustini Laita Nurjanah Laita Nurjanah, Laita LAKSMI AMBARSARI Lasmiyanti, Metty Lusiana Kresnawati Hartono Luzicoiij, Michael Edison M. Zairin Junior M.Pd Prof. Dr. I Nyoman Sudiana . Mala Nurilmala MARIA BINTANG Meilisza, Nina Melva Louisa Mirza Dikari Kusrini MS, Yulia Atika Muhaimin Muhaimin MUHAMMAD AGUS SUPRAYUDI Muhammad Dailami, Muhammad Muhammad Nafiz Nisa Widya Amanda Noorwati Sutandyo Norman Razief Azwar Norman Razief Azwar Novik Nurhidayat Novik Nurhidayat Nuke Annisa Nasution NUNUK WIDHYASTUTI Nur Bambang Priyo Utomo Nur Hasanah Nurmala Sari Nurul Khumaida Perkasa Arian Puji Lestari Rahadian Pratama Rahmawati, Fri Ramadhani Malik Abdillah Rava Raisha Putra Resti Rahmawati Putri Ridwan Putra Firmansyah Rini Kurniasih, Rini Riyan Alifbi Putera Irsal Rizka Fatriani Roedhy Poerwanto Septiany C. Palilingan Sheryn Sunni Albani Siagian, Putri Junita Siregar, Josephine Elizabeth Siti Nurjanah Siti Nurjanah Soekarno Mismana Putra Soekarno Mismana Putra, Soekarno Mismana Sogandi Sogandi Sogandi Sogandi Sudarsono Suharyanto Suharyanto Sulistiani sulistiani Suryani Suryani Suryani Suryani Suryani Suryo Wiyono Sutoro Sutoro Syaeful Abidin Syamsul Falah Tatik Khusniati Tetty Chaidamsari Tetty Chaidamsari, Tetty Tri Panji Trini Suryani Kadir Vita Rosaline Fahri Waras Nurcholis Wasrin Syafii Wijiastuti Wijiastuti Yadi Suryadi Yahdiana Harahap Yulianto YUNITA ARIAN SANI ANWAR